AP3S1

General Information

Gene Name       : AP3S1
Gene ID             : ENSG00000177879.15
Essential Gene : No

Functions

Localization

Domains (AlphaFold: AP3S1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878AP3S1ENSG00000177879.1581.0953.3867.23ENCSR000AEF
HepG2AP3S1ENSG00000177879.1554.07129.0591.56ENCSR985KAT
K562AP3S1ENSG00000177879.1560.7667.6364.19ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for AP3S1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • AP3S1 RNA is bound by 14 proteins.  







eCLIP assay for AP3S1 is not avaliable on ENCORE database.





14 proteins are bound to AP3S1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr5115249317115249375+3'-UTR4.869727.36168HepG2SUB1
chr5115249133115249195+3'-UTR,CDS3.230298.37630K562YBX3
chr5115249496115249621+3'-UTR3.087826.80128K562IGF2BP1
chr5115249415115249463+3'-UTR3.958823.78849HepG2TIAL1
chr5115249375115249451+3'-UTR3.898735.31144HepG2SUB1
chr5115249057115249078+3'-UTR,CDS,intron-Proximal3.356949.27085K562YBX3
chr5115249038115249100+3'-UTR,CDS,intron-Proximal3.952066.58004HepG2U2AF2
chr5115249408115249463+3'-UTR3.204933.85266K562NOLC1
chr5115177636115177743+5'-UTR,CDS,intron-Distal3.522817.31899HepG2DDX3X
chr5115177653115177714+5'-UTR,intron-Distal4.059513.98636K562LIN28B
chr5115177654115177712+5'-UTR,intron-Distal3.764656.19204K562YBX3
chr5115177645115177745+5'-UTR,CDS,intron-Distal4.7944313.05315K562DDX3X
chr5115205772115205823+CDS,intron-Distal3.078763.67697K562YBX3
chr5115238676115238884+CDS,intron-Distal,intron-Proximal3.391654.06432HepG2KHSRP
chr5115238655115238690+CDS,intron-Distal,intron-Proximal3.220238.20394K562YBX3
chr5115205713115205775+CDS,intron-Distal,intron-Proximal3.635513.04123K562LIN28B
chr5115215979115216039+intron-Distal4.466924.87593HepG2MATR3
chr5115215988115216053+intron-Distal4.807476.08869K562EXOSC5
chr5115212208115212323+intron-Distal4.794806.23638HepG2QKI
chr5115206082115206156+intron-Distal3.221023.06005HepG2QKI
chr5115215328115215418+intron-Distal3.211294.40773HepG2SUGP2
chr5115215980115216053+intron-Distal3.114964.40773HepG2SUGP2
chr5115216739115216836+intron-Distal3.696967.56595K562EXOSC5
chr5115236819115236898+intron-Distal3.674114.36528HepG2U2AF2
chr5115214213115214288+intron-Distal4.439704.31720HepG2MATR3
chr5115215333115215397+intron-Distal4.522015.37222HepG2MATR3
chr5115214169115214271+intron-Distal4.307476.71166K562EXOSC5
chr5115220588115220673+intron-Distal4.025976.06017HepG2QKI
chr5115215348115215414+intron-Distal4.7160410.29529K562EXOSC5
chr5115246988115247098+intron-Distal4.058934.21977HepG2HNRNPL
chr5115215309115215412+intron-Distal3.222783.56409K562MATR3
chr5115216762115216820+intron-Distal3.959253.27829HepG2MATR3
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for AP3S1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for AP3S1 is not available on ENCORE database.

  • 87 RBPs can affect the levels of AP3S1.  








The Knockdown/knockout RNA-Seq assay for AP3S1 is not available on ENCORE database.





87 RBPs can affect the gene expression of AP3S1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
AP3S1ENSG00000177879.10974.741801269.57040-0.381205.356304.56520HepG2ACO1
AP3S1ENSG00000177879.10587.47890904.36920-0.622405.886004.50300HepG2ADAR
AP3S1ENSG00000177879.101192.904402141.85590-0.844409.865308.92770HepG2AKAP1
AP3S1ENSG00000177879.101014.516601275.41810-0.330203.839702.94940HepG2AKAP8L
AP3S1ENSG00000177879.101500.968601171.682300.357203.046901.57210HepG2ATP5C1
AP3S1ENSG00000177879.10720.903201082.94250-0.587104.267203.10200HepG2BCCIP
AP3S1ENSG00000177879.101127.397901603.46060-0.508205.391004.59030HepG2BOP1
AP3S1ENSG00000177879.10988.049501731.30020-0.809203.514402.40250HepG2CCAR1
AP3S1ENSG00000177879.10969.685301269.15370-0.388305.868504.96540HepG2CKAP4
AP3S1ENSG00000177879.10636.168901178.27080-0.889206.838005.63490HepG2CNOT7
AP3S1ENSG00000177879.101124.466601762.33770-0.648206.084205.19730HepG2DDX6
AP3S1ENSG00000177879.10997.291701214.59840-0.284402.453701.80930HepG2DKC1
AP3S1ENSG00000177879.10732.89680902.58440-0.300503.215702.52150HepG2DNAJC2
AP3S1ENSG00000177879.101334.819401694.40600-0.344102.342501.79440HepG2EIF2S1
AP3S1ENSG00000177879.10787.20800984.92220-0.323302.392201.30610HepG2EIF2S2
AP3S1ENSG00000177879.101303.816701872.62800-0.522304.265003.47520HepG2EIF4A3
AP3S1ENSG00000177879.101922.081301666.539900.205702.057601.31750HepG2EIF4G1
AP3S1ENSG00000177879.101088.896601996.00580-0.8742024.6120023.12770HepG2ETF1
AP3S1ENSG00000177879.10999.559301240.47210-0.311502.442701.65820HepG2EWSR1
AP3S1ENSG00000177879.101421.746901889.06960-0.410003.235302.48870HepG2FXR1
AP3S1ENSG00000177879.10992.253101752.56450-0.820709.931408.70890HepG2G3BP1
AP3S1ENSG00000177879.10759.86980992.89890-0.385902.235401.32410HepG2GNB2L1
AP3S1ENSG00000177879.101090.385301668.72970-0.613905.622204.73100HepG2GPKOW
AP3S1ENSG00000177879.10956.750801211.99090-0.341204.087302.91460HepG2HDGF
AP3S1ENSG00000177879.10664.78710919.40330-0.467803.974203.21960HepG2HNRNPA1
AP3S1ENSG00000177879.10675.677101022.64850-0.597906.065005.06700HepG2HNRNPC
AP3S1ENSG00000177879.10907.361801128.34960-0.314502.936802.19900HepG2HNRNPF
AP3S1ENSG00000177879.101246.976701774.22060-0.508805.207104.27240HepG2HNRNPK
AP3S1ENSG00000177879.10731.703901015.88870-0.473406.442505.54960HepG2HNRNPU
AP3S1ENSG00000177879.101447.829101781.50600-0.299201.927001.35400HepG2IGF2BP2
AP3S1ENSG00000177879.101059.699701671.61500-0.657602.688701.71980HepG2IGF2BP3
AP3S1ENSG00000177879.101092.544701791.77380-0.713706.316404.74150HepG2KHSRP
AP3S1ENSG00000177879.10939.278101160.45890-0.305103.770902.58190HepG2KIF1C
AP3S1ENSG00000177879.101368.312201889.72760-0.465803.898703.12090HepG2MAGOH
AP3S1ENSG00000177879.101037.947501900.35840-0.8725010.683609.50400HepG2MATR3
AP3S1ENSG00000177879.101340.058301945.16660-0.537604.871404.04330HepG2NCBP2
AP3S1ENSG00000177879.101226.160501675.03400-0.450005.963204.84620HepG2NOL12
AP3S1ENSG00000177879.101714.657301412.038100.280002.003601.36240HepG2NSUN2
AP3S1ENSG00000177879.101233.012201732.50040-0.490704.207803.32900HepG2PABPC4
AP3S1ENSG00000177879.101057.780701697.37310-0.6823015.7021014.44740HepG2PCBP1
AP3S1ENSG00000177879.101204.707001727.16350-0.519708.918108.04960HepG2PTBP1
AP3S1ENSG00000177879.101247.519301697.38400-0.444309.131808.18700HepG2PUM1
AP3S1ENSG00000177879.101126.496701293.11920-0.199001.861501.33510HepG2PUS1
AP3S1ENSG00000177879.101234.322701870.51190-0.5997010.233209.13910HepG2QKI
AP3S1ENSG00000177879.101041.605601922.14810-0.8839024.9431023.64450HepG2NELFE
AP3S1ENSG00000177879.101282.030501790.25430-0.481708.510507.51820HepG2RECQL
AP3S1ENSG00000177879.10574.99160720.61080-0.325702.059201.52220HepG2RPS19
AP3S1ENSG00000177879.101211.06210904.704200.420706.245305.33710HepG2SAFB2
AP3S1ENSG00000177879.10871.962701576.27040-0.8542012.4353011.04170HepG2SF3B1
AP3S1ENSG00000177879.101163.249301798.15910-0.6284013.4546012.30520HepG2SF3B4
AP3S1ENSG00000177879.10778.203701055.05550-0.439106.656605.72560HepG2SMN1
AP3S1ENSG00000177879.101139.682701753.87270-0.621904.202303.23230HepG2SNRNP70
AP3S1ENSG00000177879.101590.174601884.28220-0.244802.907502.39760HepG2SRFBP1
AP3S1ENSG00000177879.101156.808701578.75770-0.448607.231006.28510HepG2SRSF5
AP3S1ENSG00000177879.10873.070601108.53830-0.344503.262302.51410HepG2SRSF7
AP3S1ENSG00000177879.101210.469601526.97710-0.335104.616303.93660HepG2SRSF9
AP3S1ENSG00000177879.101952.075001636.011900.254703.221702.67810HepG2SSB
AP3S1ENSG00000177879.10710.815901028.96800-0.533703.584502.31680HepG2STIP1
AP3S1ENSG00000177879.10322.502801795.47690-2.47700153.68850150.61790HepG2SUCLG1
AP3S1ENSG00000177879.101547.181101062.279600.542403.921202.32950HepG2SUGP2
AP3S1ENSG00000177879.101080.934201687.08240-0.6423012.0915011.04690HepG2TAF15
AP3S1ENSG00000177879.101258.144901562.13610-0.312202.685501.82620HepG2TUFM
AP3S1ENSG00000177879.101473.893001121.498800.394103.081702.42100HepG2U2AF1
AP3S1ENSG00000177879.101307.318201653.50230-0.338902.092301.37050HepG2UBE2L3
AP3S1ENSG00000177879.10438.13480626.16110-0.515203.445202.60210HepG2UCHL5
AP3S1ENSG00000177879.101604.670101289.406100.315504.912704.23660HepG2ZNF622
AP3S1ENSG00000177879.102076.385901373.727800.5959013.5868012.43110K562AGGF1
AP3S1ENSG00000177879.101996.541201509.502000.403304.019102.78740K562AKAP8
AP3S1ENSG00000177879.101904.483701429.421800.413904.155903.35190K562AKAP8L
AP3S1ENSG00000177879.10781.210301854.37410-1.2471025.9805024.38070K562AQR
AP3S1ENSG00000177879.101973.735101499.799600.396105.404304.07790K562ATP5C1
AP3S1ENSG00000177879.10303.65840441.86050-0.541103.075701.95440K562CCAR1
AP3S1ENSG00000177879.101172.048302048.59710-0.805603.232202.06970K562CNOT7
AP3S1ENSG00000177879.101942.405401538.186800.336504.278803.15540K562DKC1
AP3S1ENSG00000177879.10470.07470665.04070-0.500603.511702.47640K562EFTUD2
AP3S1ENSG00000177879.10954.70250712.154100.422802.649501.63800K562EIF3D
AP3S1ENSG00000177879.10610.05200963.79710-0.659807.387906.05380K562EIF4A3
AP3S1ENSG00000177879.101372.30070959.136200.516703.488902.67620K562G3BP2
AP3S1ENSG00000177879.10801.188801270.89740-0.665603.546902.65230K562GPKOW
AP3S1ENSG00000177879.10432.25250831.96730-0.944709.906208.83270K562HNRNPC
AP3S1ENSG00000177879.101141.220601495.23140-0.389803.779402.51690K562HNRNPL
AP3S1ENSG00000177879.10917.544601184.92490-0.368903.870302.80970K562HNRNPU
AP3S1ENSG00000177879.102104.660101516.988600.472305.669504.39460K562KIF1C
AP3S1ENSG00000177879.101898.070501452.119400.386303.732202.41720K562MAK16
AP3S1ENSG00000177879.10960.238201257.47720-0.389103.661902.58720K562MATR3
AP3S1ENSG00000177879.102284.141001699.408400.426504.885503.61160K562MBNL1
AP3S1ENSG00000177879.10656.658001240.50730-0.917705.706504.41980K562METAP2
AP3S1ENSG00000177879.101679.846101191.160900.495903.422202.42010K562NAA15
AP3S1ENSG00000177879.101011.308501205.20190-0.253103.028002.25060K562NSUN2
AP3S1ENSG00000177879.10895.952401121.12410-0.323502.339401.44450K562PCBP2
AP3S1ENSG00000177879.10539.72460812.14590-0.589504.739102.81080K562PHF6
AP3S1ENSG00000177879.10522.98280745.90520-0.512203.875502.77710K562PSIP1
AP3S1ENSG00000177879.101870.976402181.23910-0.221402.254001.38620K562PUM2
AP3S1ENSG00000177879.102459.958401417.624600.7951012.3326011.23250K562PUS1
AP3S1ENSG00000177879.101998.340601381.236400.532708.837607.80460K562RBM15
AP3S1ENSG00000177879.10752.581301173.90820-0.641407.499706.02710K562RBM22
AP3S1ENSG00000177879.10983.85940661.769300.572003.859102.27470K562RRP9
AP3S1ENSG00000177879.10933.190401189.10990-0.349603.710502.77310K562SF3A3
AP3S1ENSG00000177879.10791.75870996.99310-0.332502.863401.99310K562SF3B4
AP3S1ENSG00000177879.10865.374301200.08050-0.471704.912903.97380K562SRSF1
AP3S1ENSG00000177879.10701.250501826.13280-1.3808043.2104039.49800K562SUCLG1
AP3S1ENSG00000177879.10884.527801214.59270-0.457503.919303.07000K562TARDBP
AP3S1ENSG00000177879.101891.012502359.91900-0.319603.213101.69270K562UBE2L3
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for AP3S1 is not available on ENCORE database.





9 RBPs can affect the splicing of AP3S1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEAP3S1ENSG00000177879.10chr5+1151886751151887111151776931151778031152023661152024580.089000.000000.00002includedHepG2U2AF1
SEAP3S1ENSG00000177879.10chr5+1151886751151887111151776931151778031152023661152024580.134000.000000.00001includedHepG2U2AF2
SEAP3S1ENSG00000177879.10chr5+1151886751151887111151776931151778031152023661152024580.054000.002130.04157includedK562U2AF1
SEAP3S1ENSG00000177879.10chr5+1152023661152024581151776541151778031152307831152308550.059000.000670.06768includedHepG2LARP4
SEAP3S1ENSG00000177879.10chr5+1151886751151887111151776931151778031152023661152024580.059000.000220.02154includedHepG2TIAL1
SEAP3S1ENSG00000177879.10chr5+1151886751151887111151776931151778031152023661152024580.057000.000690.01475includedK562U2AF2
SEAP3S1ENSG00000177879.10chr5+115238581115238689115230783115230855115249058115249708-0.088000.000000.00003excludedK562HNRNPC
MXEAP3S1ENSG00000177879.10chr5+1152023661152024581152057131152058251151771771151778031152307831152308550.110000.002100.066251includedHepG2PTBP1
MXEAP3S1ENSG00000177879.10chr5+1152023661152024581152057131152058251151771771151778031152307831152308550.117000.001230.041401includedHepG2PCBP1
MXEAP3S1ENSG00000177879.10chr5+1152023661152024581152057131152058251151776541151778031152307831152308550.124000.000400.018191includedHepG2SF3B4
MXEAP3S1ENSG00000177879.10chr5+115202366115202458115230783115230855115177654115177803115238581115238689-0.094000.004100.088702includedK562DHX30

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for AP3S1 is not avaliable on ENCORE database.