USP3

General Information

Gene Name       : USP3
Gene ID             : ENSG00000140455.16
Essential Gene : No

Functions

Localization

Domains (AlphaFold: USP3)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878USP3ENSG00000140455.1637.0835.7836.43ENCSR000AEF
HepG2USP3ENSG00000140455.1623.9530.1727.06ENCSR985KAT
K562USP3ENSG00000140455.1627.9828.8128.39ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for USP3 is not avaliable on ENCORE database.



Proteins bound to RNA
  • USP3 RNA is bound by 34 proteins.  







eCLIP assay for USP3 is not avaliable on ENCORE database.





34 proteins are bound to USP3 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr156385205663852144+3'-UTR,5'-UTR,CDS,intron-Distal3.069333.26789K562YBX3
chr156384886563848942+3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal3.376634.26492HepG2BCLAF1
chr156386263163862724+3'-UTR,CDS,intron-Proximal3.460244.11795K562YBX3
chr156382487463824908+3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal4.822954.97342HepG2PPIG
chr156388364963883753+3'-UTR,intron-Distal,intron-Proximal3.663403.11181HepG2CSTF2
chr156386272463862776+3'-UTR,CDS4.076884.31428K562YBX3
chr156385205563852165+3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal3.450888.16183HepG2BCLAF1
chr156388053863880614+3'-UTR,CDS3.611845.63425HepG2BCLAF1
chr156388120063881249+3'-UTR,CDS,intron-Proximal4.6232312.15723HepG2PRPF8
chr156385503863855126+3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal4.637954.69961K562SF3B4
chr156388301663883108+3'-UTR,5'-UTR,CDS5.7061712.55471K562IGF2BP1
chr156386622663866272+3'-UTR,CDS,intron-Proximal5.018164.80701K562GPKOW
chr156388282263882913+3'-UTR,CDS,intron-Proximal3.401125.79202HepG2U2AF2
chr156384591063846001+3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal3.198868.02162HepG2BCLAF1
chr156385209463852164+3'-UTR,5'-UTR,CDS,intron-Distal3.335203.50696K562BUD13
chr156382933563829445+3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal3.303964.48980K562PRPF8
chr156388114063881221+3'-UTR,CDS,intron-Proximal3.426996.93667HepG2PPIG
chr156385038463850410+3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal4.895795.26064K562AQR
chr156384591263846001+3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal3.676894.52024HepG2PPIG
chr156386277363862830+3'-UTR,CDS,intron-Proximal3.515953.76553K562PRPF8
chr156388095363881016+3'-UTR,CDS,intron-Proximal3.865157.65975HepG2BCLAF1
chr156388344963883514+3'-UTR,5'-UTR4.451984.24698K562IGF2BP1
chr156386649763866563+3'-UTR,CDS,intron-Proximal3.590473.02321K562U2AF2
chr156384586663845934+3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal4.1357614.51197K562SF3B4
chr156385509663855144+3'-UTR,5'-UTR,CDS,intron-Distal3.775873.00996K562BUD13
chr156382933163829440+3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal4.574515.60100HepG2PRPF8
chr156386266863862752+3'-UTR,CDS3.483994.27261HepG2GRWD1
chr156388283063882926+3'-UTR,CDS,intron-Proximal3.420636.12893K562BUD13
chr156385025463850362+3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal3.405826.71503K562SF3B4
chr156379685563796939+5'-UTR4.612905.85636HepG2NCBP2
chr156379701463797075+5'-UTR,CDS,intron-Proximal4.227844.75655HepG2PRPF8
chr156383423163834292+5'-UTR,intron-Distal,intron-Proximal3.088935.01844HepG2U2AF2
chr156387755163877715+intron-Distal3.393187.19702K562KHSRP
chr156381277763812844+intron-Distal3.031213.64839HepG2HNRNPC
chr156380278963802904+intron-Distal5.4039910.41051HepG2HNRNPM
chr156386285663862946+intron-Distal,intron-Proximal3.607805.03897K562PRPF8
chr156380461663804701+intron-Distal5.4472622.20475HepG2PTBP1
chr156383225963832314+intron-Distal3.620295.56048K562KHSRP
chr156382945363829519+intron-Distal,intron-Proximal4.168549.48825HepG2U2AF2
chr156381236963812498+intron-Distal3.061794.94498HepG2HNRNPL
chr156386521763865309+intron-Distal3.762053.24593HepG2XPO5
chr156384901563849167+intron-Distal,intron-Proximal4.234657.94395K562PRPF8
chr156379714963797216+intron-Distal4.133443.85108HepG2GTF2F1
chr156382243463822524+intron-Distal5.180006.57498HepG2PCBP2
chr156386667263866758+intron-Distal,intron-Proximal3.437798.33906HepG2KHSRP
chr156382938763829451+intron-Distal,intron-Proximal5.356828.60492HepG2PCBP2
chr156384488163844956+intron-Distal3.586594.75857K562RBFOX2
chr156380416963804211+intron-Distal3.264594.00631HepG2PTBP1
chr156385041063850432+intron-Distal,intron-Proximal3.739113.79442K562AQR
chr156383930263839417+intron-Distal4.3741817.38743K562QKI
chr156379723363797353+intron-Distal3.691194.13821HepG2EXOSC5
chr156379716163797216+intron-Distal4.047503.76710K562NONO
chr156380459263804705+intron-Distal3.786228.14904K562MATR3
chr156383772563837774+intron-Distal5.235318.71243HepG2QKI
chr156380984163809894+intron-Distal4.465754.61447HepG2SUGP2
chr156382939563829453+intron-Distal,intron-Proximal3.105614.18806HepG2U2AF2
chr156387131663871408+intron-Distal5.0709310.39198K562KHDRBS1
chr156383771663837809+intron-Distal4.3973811.25076K562QKI
chr156382938163829506+intron-Distal,intron-Proximal3.900793.39067K562RBM22
chr156384894763849011+intron-Distal,intron-Proximal4.784594.13847K562AQR
chr156384897263849030+intron-Distal,intron-Proximal4.181713.45805K562KHSRP
chr156386278663862895+intron-Distal,intron-Proximal3.847656.80869K562AQR
chr156380984763809887+intron-Distal4.092693.24322HepG2MATR3
chr156379715163797224+intron-Distal3.623365.39783HepG2NKRF
chr156385524463855372+intron-Distal,intron-Proximal3.070196.21868K562KHSRP
chr156382494363825058+intron-Distal,intron-Proximal4.262513.24603K562KHSRP
chr156386669663866712+intron-Distal,intron-Proximal3.099017.02852K562KHSRP
chr156386676363866817+intron-Distal4.0098513.44586K562KHSRP
chr156379736263797446+intron-Distal3.644335.83525K562HNRNPM
chr156380458863804693+intron-Distal3.728793.00614K562U2AF2
chr156383929963839443+intron-Distal4.8609324.68444HepG2QKI
chr156386675863866805+intron-Distal4.114975.59842HepG2KHSRP
chr156386673363866788+intron-Distal3.220673.80334HepG2U2AF2
chr156382954063829623+intron-Distal4.8765910.31463HepG2U2AF2
chr156379713463797216+intron-Distal4.009233.84437HepG2PRPF4
chr156385738263857476+intron-Distal3.778995.13388HepG2HNRNPL
chr156379765363797716+intron-Distal4.632616.08412HepG2HNRNPM
chr156386671263866763+intron-Distal5.3994122.83413K562KHSRP
chr156379738163797461+intron-Distal3.652735.39685HepG2CSTF2T
chr156383174163831836+intron-Distal3.626707.84449K562KHSRP
chr156379764963797738+intron-Distal3.916914.57394K562HNRNPM
chr156382946463829517+intron-Distal3.706923.00221HepG2U2AF1
chr156382074463820850+intron-Distal4.147013.75546HepG2KHSRP
chr156379714763797229+intron-Distal4.226677.67648K562GEMIN5
chr156380841863808517+intron-Distal3.484745.60020HepG2QKI
chr156379734463797450+intron-Distal4.995657.15660HepG2HNRNPM
chr156388071963880758+intron-Distal,intron-Proximal4.777344.64001HepG2U2AF2
chr156383246463832511+intron-Distal3.416833.32861HepG2U2AF2
chr156380462863804708+intron-Distal6.7800424.47947K562PTBP1
chr156380970963809780+intron-Distal3.668695.13840HepG2MATR3
chr156382954963829628+intron-Distal4.491009.36623HepG2PCBP2
chr156388062263880722+intron-Proximal4.895794.65563K562AQR
chr156388121063881282+intron-Proximal4.508394.96013K562PRPF8
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for USP3 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for USP3 is not available on ENCORE database.

  • 68 RBPs can affect the levels of USP3.  








The Knockdown/knockout RNA-Seq assay for USP3 is not available on ENCORE database.





68 RBPs can affect the gene expression of USP3 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
USP3ENSG00000140455.12917.21880763.241400.265002.427801.85130HepG2ACO1
USP3ENSG00000140455.12848.024901381.41220-0.704006.398005.62660HepG2AKAP1
USP3ENSG00000140455.121058.986501291.71450-0.286602.852902.15760HepG2AUH
USP3ENSG00000140455.12987.32750668.325400.562904.348603.16980HepG2BCCIP
USP3ENSG00000140455.12965.73410763.019200.339803.909803.14540HepG2CKAP4
USP3ENSG00000140455.12921.202901412.13480-0.616303.792102.88990HepG2CNOT7
USP3ENSG00000140455.12564.29300412.889200.450603.129801.99070HepG2CSTF2
USP3ENSG00000140455.12961.604401293.85940-0.428207.101205.99380HepG2DAZAP1
USP3ENSG00000140455.12832.73960705.863100.238402.046101.31970HepG2DDX19B
USP3ENSG00000140455.12920.30460727.097300.339902.382501.54020HepG2DDX24
USP3ENSG00000140455.12664.008101323.33940-0.9949013.5055012.22390HepG2DDX3X
USP3ENSG00000140455.12993.18280730.200600.443705.306304.42290HepG2DKC1
USP3ENSG00000140455.12585.94040763.70750-0.382304.273203.49580HepG2DNAJC2
USP3ENSG00000140455.12772.913701092.81400-0.499703.839603.14840HepG2EIF2S1
USP3ENSG00000140455.12923.38310701.838100.395703.063701.93170HepG2EIF3G
USP3ENSG00000140455.12634.579201207.74570-0.9284010.515809.29160HepG2EIF4A3
USP3ENSG00000140455.121771.886701276.401900.473107.831506.55630HepG2EIF4G1
USP3ENSG00000140455.12862.015001222.72390-0.504304.783203.72970HepG2EIF4G2
USP3ENSG00000140455.121175.454101483.05690-0.335404.117103.40870HepG2ETF1
USP3ENSG00000140455.12834.49890669.863700.316902.110701.41620HepG2FUBP3
USP3ENSG00000140455.12791.964101130.32740-0.513203.913103.12880HepG2G3BP1
USP3ENSG00000140455.12573.49380746.68520-0.380702.469701.51190HepG2GNB2L1
USP3ENSG00000140455.12550.89740865.27300-0.651406.468805.44450HepG2HNRNPC
USP3ENSG00000140455.12640.49470859.55260-0.424404.934104.14440HepG2HNRNPU
USP3ENSG00000140455.12905.382001148.98580-0.343802.151801.54740HepG2IGF2BP2
USP3ENSG00000140455.12869.797201218.81460-0.486703.814403.04440HepG2MAGOH
USP3ENSG00000140455.12946.518801225.66460-0.372902.215301.64750HepG2MATR3
USP3ENSG00000140455.12744.686101254.55900-0.752507.849406.80780HepG2NCBP2
USP3ENSG00000140455.12706.153401045.65880-0.566403.281801.71460HepG2NKRF
USP3ENSG00000140455.12784.714701117.37280-0.509904.035803.17420HepG2PABPC4
USP3ENSG00000140455.121089.85640837.476400.379904.490103.52980HepG2PRPF4
USP3ENSG00000140455.12665.81820507.019300.393002.456301.69330HepG2PRPF8
USP3ENSG00000140455.12876.803601224.69800-0.482104.972404.20150HepG2PUF60
USP3ENSG00000140455.121119.154001300.04460-0.216202.477201.90910HepG2PUM1
USP3ENSG00000140455.12914.96210777.402700.234902.009401.46590HepG2PUS1
USP3ENSG00000140455.12575.54190886.83400-0.623703.757902.65810HepG2RPS10
USP3ENSG00000140455.12787.230901417.90310-0.848908.047806.70280HepG2RPS3A
USP3ENSG00000140455.12671.52030501.560600.420902.520001.76590HepG2RRP9
USP3ENSG00000140455.12612.48390765.47230-0.321702.968002.30600HepG2SAFB2
USP3ENSG00000140455.121325.671401018.804300.379702.162501.56530HepG2SF3A3
USP3ENSG00000140455.12921.59420693.759500.409602.984502.25200HepG2SF3B1
USP3ENSG00000140455.12747.63580892.67450-0.255802.466701.85450HepG2SMN1
USP3ENSG00000140455.121685.218501400.041200.267403.236202.70780HepG2SRFBP1
USP3ENSG00000140455.12847.270201209.17930-0.513107.999407.00610HepG2SRSF5
USP3ENSG00000140455.121375.867801088.863200.337403.487702.87080HepG2TAF15
USP3ENSG00000140455.12705.890701079.56210-0.612902.394801.40240HepG2TBRG4
USP3ENSG00000140455.12595.13330835.23290-0.489004.851604.22750HepG2TIAL1
USP3ENSG00000140455.12722.41360903.52510-0.322703.208902.46770HepG2UPF1
USP3ENSG00000140455.121064.56480872.315800.287202.917102.30580HepG2UTP3
USP3ENSG00000140455.12946.201401270.01410-0.424602.317701.32230HepG2XPO5
USP3ENSG00000140455.121008.99140643.938000.647806.280705.20320HepG2XRN2
USP3ENSG00000140455.122143.311201757.542000.286203.661003.02470K562AGGF1
USP3ENSG00000140455.121961.834301677.160900.226102.400501.78760K562DDX47
USP3ENSG00000140455.122302.733401968.042200.226502.248001.46930K562DKC1
USP3ENSG00000140455.121546.107901249.779600.306903.413602.62760K562EIF2S2
USP3ENSG00000140455.121758.060302098.34990-0.255302.625801.70820K562EIF4G2
USP3ENSG00000140455.121393.931001018.701400.452302.310101.67180K562G3BP2
USP3ENSG00000140455.12868.306001202.64940-0.469905.788104.16940K562GLRX3
USP3ENSG00000140455.12648.14760860.76170-0.409303.160902.52870K562HNRNPC
USP3ENSG00000140455.122294.341801601.264300.518805.956604.80200K562HSPD1
USP3ENSG00000140455.122387.191301940.872600.298502.528201.74310K562KIF1C
USP3ENSG00000140455.122345.761201857.826900.336302.935401.82050K562MAK16
USP3ENSG00000140455.122056.312701523.989000.432102.756401.87510K562NAA15
USP3ENSG00000140455.121203.586701404.82680-0.223102.554001.83350K562NSUN2
USP3ENSG00000140455.121377.940601043.223800.401403.564202.45670K562PCBP2
USP3ENSG00000140455.123171.695701813.812500.8061013.0992011.96360K562PUS1
USP3ENSG00000140455.122222.542701767.149800.330703.866803.18230K562RBM15
USP3ENSG00000140455.121802.132401140.904100.659402.611401.43190K562SNRNP200
USP3ENSG00000140455.121201.20920860.877100.480503.777002.24850K562SSB
USP3ENSG00000140455.12727.528001130.19270-0.635506.699905.55690K562TARDBP
USP3ENSG00000140455.121297.44170987.178300.394202.585601.53240K562U2AF1
USP3ENSG00000140455.121430.916001019.630100.488806.101004.91410K562U2AF2
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for USP3 is not available on ENCORE database.





15 RBPs can affect the splicing of USP3 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEUSP3ENSG00000140455.12chr15+6382600163826117638248456382490663829223638293550.221000.000030.00108includedK562SRSF1
SEUSP3ENSG00000140455.12chr15+6383425363834391638293366382935563845913638459970.091000.000040.00130includedK562SRSF1
SEUSP3ENSG00000140455.12chr15+638490396384912163848865638489476385030463850387-0.057000.006320.09124excludedK562SRSF1
SEUSP3ENSG00000140455.12chr15+638212126382136563796810637970296382484563824906-0.283000.005550.08009excludedK562SF3B4
SEUSP3ENSG00000140455.12chr15+6384903963849121638488656384894763850304638503870.066000.001330.03393includedHepG2HNRNPK
SEUSP3ENSG00000140455.12chr15+6382600163826117638248456382490663829223638293550.131000.005640.05835includedHepG2U2AF2
SEUSP3ENSG00000140455.12chr15+6382600163826117638248456382490663829223638293550.138000.000090.00153includedK562AQR
SEUSP3ENSG00000140455.12chr15+638260016382611763824845638249066382922363829355-0.114000.000380.05924excludedK562DROSHA
SEUSP3ENSG00000140455.12chr15+6382121263821365637968106379702963824845638249060.232000.000390.03727includedHepG2DDX6
SEUSP3ENSG00000140455.12chr15+6382600163826117638248456382490663829223638293550.204000.000030.01215includedHepG2CDC40
SEUSP3ENSG00000140455.12chr15+6383425363834391638293366382935563845913638459970.089000.000070.00293includedHepG2SRSF1
SEUSP3ENSG00000140455.12chr15+638212126382136563796810637970296382484563824906-0.252000.000420.02454excludedHepG2PCBP1
SEUSP3ENSG00000140455.12chr15+6382600163826117638248456382490663829223638293550.139000.000320.05745includedK562UPF1
SEUSP3ENSG00000140455.12chr15+6388073163880775638805036388062263880900638810140.126000.000010.00079includedK562TARDBP
SEUSP3ENSG00000140455.12chr15+6382600163826117638248456382490663829223638293550.307000.006330.08359includedK562HNRNPC
SEUSP3ENSG00000140455.12chr15+6382121263821365637968106379702963824845638249060.215000.005060.06996includedK562HNRNPC
SEUSP3ENSG00000140455.12chr15+6383425363834391638293366382935563845913638459970.080000.000020.00061includedK562HNRNPC
MXEUSP3ENSG00000140455.12chr15+63824845638249066382922363829355637969326379702963845913638459970.190000.001920.053851includedK562PTBP1
MXEUSP3ENSG00000140455.12chr15+6382484563824906638260016382611763796932637970296382922363829355-0.095000.001140.010242includedK562AQR
MXEUSP3ENSG00000140455.12chr15+63824845638249066382922363829355637969326379702963845913638459970.178000.008240.086631includedHepG2HNRNPUL1
MXEUSP3ENSG00000140455.12chr15+6382484563824906638292236382935563796932637970296384591363845997-0.122000.003300.081672includedK562TAF15

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for USP3 is not avaliable on ENCORE database.