TMEM43

General Information

Gene Name       : TMEM43
Gene ID             : ENSG00000170876.7
Essential Gene : No

Functions

Localization

Domains (AlphaFold: TMEM43)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878TMEM43ENSG00000170876.710.6511.9211.29ENCSR000AEF
HepG2TMEM43ENSG00000170876.743.8644.7444.30ENCSR985KAT
K562TMEM43ENSG00000170876.730.0030.9830.49ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for TMEM43 is not avaliable on ENCORE database.



Proteins bound to RNA
  • TMEM43 RNA is bound by 18 proteins.  







eCLIP assay for TMEM43 is not avaliable on ENCORE database.





18 proteins are bound to TMEM43 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr31418355214183621+3'-UTR,intron-Distal3.546283.68605HepG2AKAP1
chr31418343914183532+3'-UTR,intron-Distal4.552968.55060HepG2UPF1
chr31418330814183398+3'-UTR,intron-Distal3.270574.09794HepG2IGF2BP1
chr31418438314184519+3'-UTR,intron-Distal3.298986.78524K562YBX3
chr31418335014183521+3'-UTR,intron-Distal4.6987110.54173HepG2AKAP1
chr31418357014183618+3'-UTR,intron-Distal5.028265.17229HepG2UPF1
chr31417094714171047+3'-UTR,CDS4.598499.17911HepG2RPS3
chr31418452714184615+3'-UTR,intron-Distal4.215447.12652K562UPF1
chr31418329614183439+3'-UTR,intron-Distal4.7794512.07264HepG2UPF1
chr31418409214184138+3'-UTR,intron-Distal4.310633.87930K562UPF1
chr31417314614173211+3'-UTR,CDS,intron-Proximal4.3864714.13124HepG2PRPF8
chr31417311514173152+3'-UTR,CDS4.141445.51172HepG2SND1
chr31418480414184848+3'-UTR,intron-Distal3.993333.67607K562YBX3
chr31418473514184805+3'-UTR,intron-Distal4.263557.12652K562UPF1
chr31417230914172356+3'-UTR,CDS,intron-Proximal4.203127.37475HepG2U2AF2
chr31418393814183990+3'-UTR,intron-Distal4.567924.46422K562UPF1
chr31418466114184735+3'-UTR,intron-Distal4.222197.50817K562UPF1
chr31418366814183827+3'-UTR,intron-Distal5.1485218.39943HepG2UPF1
chr31418392714184034+3'-UTR,intron-Distal4.844806.92572HepG2AKAP1
chr31418367914183753+3'-UTR,intron-Distal3.276016.61971K562YBX3
chr31417436614174436+3'-UTR,CDS,intron-Proximal4.300014.01763HepG2GRWD1
chr31416658514166628+5'-UTR3.912383.48187K562RBM15
chr31416655514166647+5'-UTR3.996254.46401K562DDX3X
chr31416655514166620+5'-UTR5.013238.17272HepG2DDX3X
chr31416662014166699+5'-UTR,CDS3.851797.94128HepG2DDX3X
chr31418309114183133+CDS,intron-Distal,intron-Proximal3.319003.41653K562SND1
chr31417528214175345+CDS,intron-Proximal4.508394.96013K562PRPF8
chr31418060914180683+CDS,intron-Proximal4.496755.32775HepG2SF3B4
chr31417627414176399+CDS,intron-Proximal4.520765.18972HepG2GRWD1
chr31418069414180765+CDS3.8611810.29465HepG2SND1
chr31417529314175345+CDS,intron-Proximal5.230264.68690HepG2PRPF8
chr31418070214180764+CDS3.403224.77467K562SND1
chr31418068314180745+CDS3.693446.13978HepG2PPIG
chr31418074514180793+CDS4.015933.49332HepG2PPIG
chr31418313314183207+CDS,intron-Distal3.878979.24069K562SND1
chr31417638314176437+CDS,intron-Proximal4.827995.68502HepG2PRPF8
chr31417667314176733+CDS,intron-Proximal4.974647.95584K562SND1
chr31417730514177360+CDS,intron-Proximal5.1354420.12489HepG2SND1
chr31417739214177409+CDS,intron-Proximal3.804454.76748HepG2SND1
chr31417737214177392+CDS4.241325.79199HepG2SND1
chr31417528914175339+CDS,intron-Proximal3.698833.12746HepG2GRWD1
chr31417730714177337+CDS4.698685.22159K562SND1
chr31417638214176391+CDS5.042476.43734HepG2SND1
chr31418313114183199+CDS,intron-Distal3.186517.97192HepG2SND1
chr31418319914183284+CDS,intron-Distal4.1646910.75945HepG2SND1
chr31417617614176282+CDS,intron-Proximal4.993205.40008K562SF3B4
chr31417667214176733+CDS,intron-Proximal4.8237022.74441HepG2SND1
chr31418067914180694+CDS,intron-Proximal3.529794.24433HepG2SND1
chr31417665714176672+CDS,intron-Proximal5.235257.03502HepG2SND1
chr31417153414171591+intron-Distal5.057737.11021HepG2PTBP1
chr31417678414176849+intron-Distal,intron-Proximal3.492044.78164HepG2PRPF8
chr31417136714171427+intron-Distal5.461848.50063K562PTBP1
chr31417647114176539+intron-Distal,intron-Proximal3.534014.77128HepG2RBFOX2
chr31417654214176644+intron-Distal,intron-Proximal3.103814.56001HepG2SF3B4
chr31416979414169890+intron-Distal3.828803.41442HepG2HNRNPK
chr31417159114171644+intron-Distal4.373636.90077HepG2PTBP1
chr31417159614171644+intron-Distal5.4730215.04840K562PTBP1
chr31417127014171314+intron-Distal4.887055.81225K562PTBP1
chr31416674414166809+intron-Distal,intron-Proximal4.809935.00814HepG2RBM22
chr31417137014171420+intron-Distal3.297873.00914HepG2PTBP1
chr31418060314180676+intron-Proximal4.889204.90235K562SF3B4
chr31417245614172508+intron-Proximal4.623634.13847K562AQR
chr31417398814174035+intron-Proximal3.893176.32943HepG2SF3B4
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for TMEM43 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for TMEM43 is not available on ENCORE database.

  • 91 RBPs can affect the levels of TMEM43.  








The Knockdown/knockout RNA-Seq assay for TMEM43 is not available on ENCORE database.





91 RBPs can affect the gene expression of TMEM43 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
TMEM43ENSG00000170876.72013.162601763.695700.190802.121601.57490HepG2ACO1
TMEM43ENSG00000170876.73228.845502482.151800.379302.657702.13610HepG2AKAP1
TMEM43ENSG00000170876.71077.185902053.73240-0.9310014.0764012.43330HepG2ASCC1
TMEM43ENSG00000170876.71328.510001951.20000-0.554605.739404.65120HepG2CIRBP
TMEM43ENSG00000170876.71992.310001763.343100.176001.998301.42120HepG2CKAP4
TMEM43ENSG00000170876.7955.231201523.77030-0.673704.463403.48810HepG2CNOT7
TMEM43ENSG00000170876.7743.137101170.06400-0.654906.522504.52150HepG2DDX28
TMEM43ENSG00000170876.72351.130101544.657100.606005.563304.51150HepG2DDX55
TMEM43ENSG00000170876.71290.967101687.38680-0.386305.576204.67630HepG2DKC1
TMEM43ENSG00000170876.71690.329801382.970100.289403.150302.40400HepG2DNAJC21
TMEM43ENSG00000170876.71573.031302112.71870-0.425602.537701.87730HepG2EIF4B
TMEM43ENSG00000170876.72633.506802090.255100.333202.763901.94920HepG2EIF4G2
TMEM43ENSG00000170876.71107.906301476.84400-0.414704.066703.12120HepG2FUBP3
TMEM43ENSG00000170876.71356.343902030.88820-0.582405.645404.70850HepG2G3BP1
TMEM43ENSG00000170876.71083.902501433.77130-0.403602.796502.15210HepG2GPKOW
TMEM43ENSG00000170876.71490.977102014.85540-0.434409.774008.58350HepG2HNRNPL
TMEM43ENSG00000170876.71065.653301368.27880-0.360602.590501.97770HepG2HNRNPLL
TMEM43ENSG00000170876.71349.446101542.76640-0.193201.803401.30480HepG2HNRNPU
TMEM43ENSG00000170876.71593.735701940.18710-0.283802.643601.93520HepG2IGF2BP1
TMEM43ENSG00000170876.71226.948601575.88510-0.361106.216605.16110HepG2ILF2
TMEM43ENSG00000170876.71771.509102190.22240-0.306102.026201.46100HepG2MAGOH
TMEM43ENSG00000170876.72258.861801605.854300.492205.705904.58240HepG2MSI2
TMEM43ENSG00000170876.71732.871801348.592900.361602.997301.73370HepG2NAA15
TMEM43ENSG00000170876.72663.799302193.254200.280302.973902.18370HepG2NOL12
TMEM43ENSG00000170876.7762.790701213.27650-0.669507.268906.09250HepG2NSUN2
TMEM43ENSG00000170876.7852.237402007.40030-1.2360022.5288020.52220HepG2PABPC4
TMEM43ENSG00000170876.71568.912501971.80670-0.329804.900104.12830HepG2PCBP1
TMEM43ENSG00000170876.71500.128902093.62140-0.480905.928805.10070HepG2PUF60
TMEM43ENSG00000170876.73396.849202222.434400.6120022.7287021.36450HepG2PUM1
TMEM43ENSG00000170876.73028.255602220.834100.447306.565405.54850HepG2PUM2
TMEM43ENSG00000170876.71396.843701796.44290-0.363005.905205.06570HepG2PUS1
TMEM43ENSG00000170876.71332.496402173.00880-0.7056014.7645013.48390HepG2QKI
TMEM43ENSG00000170876.72603.568902120.976200.295703.095502.19320HepG2RBM15
TMEM43ENSG00000170876.73296.670802234.514200.5609012.2872011.35530HepG2RBM22
TMEM43ENSG00000170876.71614.471501972.11280-0.288702.588401.93310HepG2RBM25
TMEM43ENSG00000170876.71673.177402232.90480-0.416307.198206.39640HepG2NELFE
TMEM43ENSG00000170876.71579.857502079.58680-0.396506.695805.79690HepG2RECQL
TMEM43ENSG00000170876.7913.316601373.90280-0.5891012.0562010.85950HepG2SAFB2
TMEM43ENSG00000170876.71830.804002088.93810-0.190301.957101.44530HepG2SF3B4
TMEM43ENSG00000170876.7660.474401506.90340-1.1900012.5247010.87690HepG2SNRNP70
TMEM43ENSG00000170876.73955.532002523.777300.6482023.0946022.01540HepG2SRFBP1
TMEM43ENSG00000170876.71772.566902180.36970-0.298704.349603.78930HepG2SRSF1
TMEM43ENSG00000170876.72761.796902067.101700.417908.028807.03420HepG2SRSF5
TMEM43ENSG00000170876.71705.385502191.19380-0.361606.154905.44570HepG2SSB
TMEM43ENSG00000170876.72090.430501325.234200.657505.172903.53880HepG2STAU1
TMEM43ENSG00000170876.7813.645001537.64550-0.9183011.6230010.39710HepG2SUPV3L1
TMEM43ENSG00000170876.71568.831101959.71970-0.321003.843503.20130HepG2TAF15
TMEM43ENSG00000170876.7967.560301499.09240-0.631709.920909.07770HepG2TIAL1
TMEM43ENSG00000170876.71818.241101512.486200.265503.409402.79780HepG2TRIM56
TMEM43ENSG00000170876.71260.882201692.27100-0.424507.328906.28310HepG2UPF1
TMEM43ENSG00000170876.72394.633701633.819400.5515013.4074012.23660HepG2UTP3
TMEM43ENSG00000170876.71018.386901455.85680-0.515603.070301.73650HepG2XRCC5
TMEM43ENSG00000170876.71074.890601513.64450-0.493804.423603.51420HepG2XRN2
TMEM43ENSG00000170876.71222.674901486.44170-0.281803.671302.91540HepG2ZC3H8
TMEM43ENSG00000170876.72167.350401718.110800.335002.740501.52530K562ABCF1
TMEM43ENSG00000170876.7615.78020903.36060-0.552907.209206.35650K562AGGF1
TMEM43ENSG00000170876.7773.29100992.60850-0.360202.752101.77410K562AKAP8
TMEM43ENSG00000170876.71198.732301614.42830-0.429504.064203.38000K562AQR
TMEM43ENSG00000170876.71480.666201187.743200.317903.421001.92650K562BCCIP
TMEM43ENSG00000170876.71014.17450721.739900.490704.251602.88580K562CCAR1
TMEM43ENSG00000170876.71386.923201079.604100.361303.438702.10520K562CCDC124
TMEM43ENSG00000170876.72264.302101470.178100.6230013.9595011.55910K562CPEB4
TMEM43ENSG00000170876.71104.31450691.820500.674608.799106.83220K562DDX3X
TMEM43ENSG00000170876.71969.875901521.533100.372505.657104.77580K562DDX47
TMEM43ENSG00000170876.7767.65990978.82330-0.350602.274401.44700K562EFTUD2
TMEM43ENSG00000170876.71130.21420759.758500.572907.095205.11670K562EIF2S1
TMEM43ENSG00000170876.71098.32290798.490500.459905.601104.48440K562EIF3G
TMEM43ENSG00000170876.71209.66670722.726900.743009.678408.13290K562EIF4A3
TMEM43ENSG00000170876.73299.719702017.039000.7100020.5122018.13010K562EIF4G2
TMEM43ENSG00000170876.71203.35700854.246400.494205.398803.07660K562FASTKD2
TMEM43ENSG00000170876.71243.30840751.596200.726108.821007.81400K562FXR1
TMEM43ENSG00000170876.71360.55830981.335800.471303.925402.19050K562GEMIN5
TMEM43ENSG00000170876.7479.70440947.32610-0.981703.215901.87060K562HNRNPA2B1
TMEM43ENSG00000170876.71795.52930971.857600.8855017.0763015.67310K562HNRNPC
TMEM43ENSG00000170876.7656.73020997.59090-0.603106.781305.35410K562KIF1C
TMEM43ENSG00000170876.71363.58530959.601000.506805.910104.66520K562MAGOH
TMEM43ENSG00000170876.7739.82320954.90620-0.368202.516401.50610K562MAK16
TMEM43ENSG00000170876.71177.98230957.624100.298702.320901.48200K562MATR3
TMEM43ENSG00000170876.71339.39500973.285000.460504.713403.55130K562METAP2
TMEM43ENSG00000170876.7575.20950783.31650-0.445502.367001.56600K562NAA15
TMEM43ENSG00000170876.71031.61530721.761000.515205.300103.60190K562NCBP2
TMEM43ENSG00000170876.7736.59690938.10090-0.348902.840701.47340K562PCBP1
TMEM43ENSG00000170876.7656.96150853.77110-0.378002.699101.73260K562PCBP2
TMEM43ENSG00000170876.71219.55850948.699500.362203.059901.54960K562PHF6
TMEM43ENSG00000170876.71291.09310932.327300.469605.309904.41520K562PTBP1
TMEM43ENSG00000170876.73268.470402340.433400.481708.805306.81620K562PUM1
TMEM43ENSG00000170876.72768.925702293.642600.271603.913002.76820K562PUM2
TMEM43ENSG00000170876.7755.74440908.29900-0.265301.968201.45320K562RBM15
TMEM43ENSG00000170876.71122.93240893.882200.329002.387701.61190K562RBM22
TMEM43ENSG00000170876.7361.98900583.05680-0.687706.480904.36040K562RBM25
TMEM43ENSG00000170876.7740.61540478.267200.630804.704103.35110K562RPS3
TMEM43ENSG00000170876.71324.85480935.474000.502005.409203.89230K562SAFB
TMEM43ENSG00000170876.71640.593501320.980400.312503.511902.59980K562SF3A3
TMEM43ENSG00000170876.7422.26620639.19640-0.598106.107904.80070K562SF3B4
TMEM43ENSG00000170876.71869.075901353.371800.465709.548207.92550K562SRPK2
TMEM43ENSG00000170876.7604.17250823.67320-0.447104.124602.51340K562SSB
TMEM43ENSG00000170876.71905.436101482.104900.362402.753201.50770K562STAU1
TMEM43ENSG00000170876.71662.746301053.004900.6590010.935309.30430K562SYNCRIP
TMEM43ENSG00000170876.71235.84740924.993700.417903.372102.58860K562TARDBP
TMEM43ENSG00000170876.71078.58830838.095800.363902.408301.53900K562TIAL1
TMEM43ENSG00000170876.71161.27540890.105200.383603.241102.19870K562TRIM56
TMEM43ENSG00000170876.7355.69580595.85400-0.744305.867204.14640K562U2AF1
TMEM43ENSG00000170876.7445.29760615.39790-0.466703.836002.88980K562U2AF2
TMEM43ENSG00000170876.71730.669601419.492300.285903.464902.66670K562UPF1
TMEM43ENSG00000170876.71851.401401297.897500.512303.835002.40800K562UTP3
TMEM43ENSG00000170876.71558.589801263.051800.303204.113603.09660K562WDR43
TMEM43ENSG00000170876.72512.082501912.538700.393304.267102.65370K562WRN
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for TMEM43 is not available on ENCORE database.





5 RBPs can affect the splicing of TMEM43 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SETMEM43ENSG00000170876.7chr3+1417035414170585141665141416670514170911141710610.064000.000520.09183includedHepG2UCHL5
SETMEM43ENSG00000170876.7chr3+1417035414170585141665141416670514170911141710610.096000.000000.00089includedHepG2HNRNPL
SETMEM43ENSG00000170876.7chr3+1417035414170585141665141416670514170911141710610.157000.000030.00388includedK562HNRNPL
SETMEM43ENSG00000170876.7chr3+1417035414170585141665141416670514170911141710610.130000.000080.03488includedK562PPIL4
SETMEM43ENSG00000170876.7chr3+1417035414170585141665141416670514170911141709990.053000.000440.05083includedHepG2TAF15
A5SSTMEM43ENSG00000170876.7chr3+1417091114171146141709111417106114172321141724560.206000.000020.00051longerK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for TMEM43 is not avaliable on ENCORE database.