TMEM138

General Information

Gene Name       : TMEM138
Gene ID             : ENSG00000149483.11
Essential Gene : No

Functions

Localization

Domains (AlphaFold: TMEM138)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878TMEM138ENSG00000149483.1145.9356.1951.06ENCSR000AEF
HepG2TMEM138ENSG00000149483.1138.2441.2339.73ENCSR985KAT
K562TMEM138ENSG00000149483.1179.0668.4873.77ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for TMEM138 is not avaliable on ENCORE database.



Proteins bound to RNA
  • TMEM138 RNA is bound by 18 proteins.  







eCLIP assay for TMEM138 is not avaliable on ENCORE database.





18 proteins are bound to TMEM138 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr116113395361134010+3'-UTR,intron-Distal3.289224.02778HepG2HNRNPC
chr116113546161135566+3'-UTR,CDS,intron-Proximal4.856069.23542K562EFTUD2
chr116113546761135520+3'-UTR,CDS,intron-Proximal4.212335.93840HepG2PRPF8
chr116113372761133818+3'-UTR,intron-Distal,intron-Proximal3.399308.81610K562PRPF8
chr116113427861134364+3'-UTR,intron-Distal3.400975.75313HepG2NKRF
chr116113536361135449+3'-UTR,CDS,intron-Proximal3.793557.58883K562AQR
chr116113639361136541+3'-UTR4.254853.72005K562MATR3
chr116113645161136498+3'-UTR3.497344.51666K562RBM15
chr116113395561133964+3'-UTR,intron-Distal3.398974.98422K562PRPF8
chr116113614161136187+3'-UTR,CDS,intron-Distal,intron-Proximal3.090623.04831K562RBM15
chr116113636461136464+3'-UTR4.575519.31157K562PCBP1
chr116113623261136329+3'-UTR,intron-Proximal4.929267.23707K562RBM15
chr116113636361136459+3'-UTR5.0507325.82804HepG2PCBP2
chr116113365461133720+3'-UTR,CDS,intron-Proximal6.262927.70650HepG2PRPF8
chr116113395261134011+3'-UTR,intron-Distal3.972894.36164K562HNRNPC
chr116113396461133996+3'-UTR,intron-Distal3.104244.95232K562PRPF8
chr116113638261136483+3'-UTR3.196884.82148HepG2PTBP1
chr116113539961135503+3'-UTR,CDS,intron-Proximal3.373037.24602HepG2GRWD1
chr116113539461135507+3'-UTR,CDS,intron-Proximal3.208196.07830K562ZNF622
chr116113601061136068+3'-UTR,intron-Distal,intron-Proximal4.744453.91589K562SF3B4
chr116113421061134263+3'-UTR,intron-Distal4.616353.20376K562XRN2
chr116113494061135014+3'-UTR,intron-Distal3.876013.56019HepG2GRWD1
chr116113420061134253+3'-UTR,intron-Distal4.513455.03029HepG2NKRF
chr116113177161131850+5'-UTR,intron-Proximal4.774637.71151HepG2GRWD1
chr116113178261131859+5'-UTR,intron-Proximal4.133983.18234K562BUD13
chr116112985761129934+5'-UTR,intron-Proximal4.346737.46483HepG2PRPF8
chr116113351561133678+5'-UTR,CDS,intron-Proximal3.550954.20072K562IGF2BP1
chr116113177361131850+5'-UTR,intron-Proximal4.349943.82843HepG2PPIG
chr116112986561129932+5'-UTR,intron-Proximal3.433484.07440K562PRPF8
chr116113362661133696+CDS,intron-Proximal3.359803.80299HepG2GRWD1
chr116113605461136101+CDS,intron-Distal,intron-Proximal4.4056415.43672HepG2U2AF2
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for TMEM138 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for TMEM138 is not available on ENCORE database.

  • 78 RBPs can affect the levels of TMEM138.  








The Knockdown/knockout RNA-Seq assay for TMEM138 is not available on ENCORE database.





78 RBPs can affect the gene expression of TMEM138 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
TMEM138ENSG00000149483.7424.37100321.218800.401702.828902.21550HepG2ACO1
TMEM138ENSG00000149483.7427.84720314.498600.443901.902801.45190HepG2AKAP1
TMEM138ENSG00000149483.7467.33590328.364600.509102.679001.65680HepG2AKAP8
TMEM138ENSG00000149483.7596.00380361.864600.719806.537605.66370HepG2BOP1
TMEM138ENSG00000149483.7340.26190247.226500.460702.085301.40740HepG2CIRBP
TMEM138ENSG00000149483.7480.57210321.096100.581605.805404.90580HepG2CKAP4
TMEM138ENSG00000149483.7227.40930332.22140-0.546902.612601.94230HepG2CPSF6
TMEM138ENSG00000149483.7459.05280271.028500.760106.211905.24290HepG2DDX21
TMEM138ENSG00000149483.7432.35370301.260600.521102.783502.15590HepG2DDX3X
TMEM138ENSG00000149483.7408.47060307.305700.410502.564101.90920HepG2DKC1
TMEM138ENSG00000149483.7426.42600274.925000.633202.924402.26710HepG2EIF4A3
TMEM138ENSG00000149483.7395.46280267.689400.562902.427801.78190HepG2EIF4B
TMEM138ENSG00000149483.7303.60290506.15670-0.737405.847504.68210HepG2EIF4G2
TMEM138ENSG00000149483.7256.69010159.405100.687203.699502.79850HepG2FUBP3
TMEM138ENSG00000149483.7490.67590277.405800.822706.442705.41070HepG2FXR1
TMEM138ENSG00000149483.7438.61720257.325100.769305.383904.46840HepG2G3BP1
TMEM138ENSG00000149483.7407.01470273.195900.575003.260702.28890HepG2G3BP2
TMEM138ENSG00000149483.7246.22590376.62610-0.613203.190802.50830HepG2GPKOW
TMEM138ENSG00000149483.7374.02040279.670100.419301.977201.41960HepG2HNRNPA1
TMEM138ENSG00000149483.7633.78990260.587001.2821016.2476014.70390HepG2HNRNPK
TMEM138ENSG00000149483.7393.29830487.83500-0.310801.999301.41470HepG2HNRNPL
TMEM138ENSG00000149483.7508.46400261.562000.958905.912604.96230HepG2IGF2BP2
TMEM138ENSG00000149483.7396.57340263.092900.591902.832401.81780HepG2KHSRP
TMEM138ENSG00000149483.7591.94080411.367400.524902.829301.99100HepG2LARP4
TMEM138ENSG00000149483.7565.00370277.502701.025709.862108.64280HepG2MAGOH
TMEM138ENSG00000149483.7643.78120279.053001.2059012.5331011.25810HepG2MATR3
TMEM138ENSG00000149483.7517.50870320.094400.693005.598004.48220HepG2MSI2
TMEM138ENSG00000149483.7623.59630285.623801.1264011.7210010.46000HepG2NCBP2
TMEM138ENSG00000149483.7223.79380318.67370-0.509902.384401.68830HepG2NSUN2
TMEM138ENSG00000149483.7480.45070254.355700.917407.708006.51890HepG2PABPC4
TMEM138ENSG00000149483.7434.90160278.310100.643905.493804.77760HepG2PTBP1
TMEM138ENSG00000149483.7299.13030506.94880-0.761105.941905.11280HepG2PUF60
TMEM138ENSG00000149483.7453.31670327.174500.470403.841303.13890HepG2PUS1
TMEM138ENSG00000149483.7526.10790301.388600.803608.267807.27630HepG2QKI
TMEM138ENSG00000149483.7533.30350309.721400.783908.529807.67620HepG2NELFE
TMEM138ENSG00000149483.7437.40290288.483300.600404.985004.18770HepG2RECQL
TMEM138ENSG00000149483.7307.89600198.388400.634003.689502.98990HepG2RPS19
TMEM138ENSG00000149483.7508.24600320.897900.663304.015103.19700HepG2SF3A3
TMEM138ENSG00000149483.7251.99170355.76930-0.497602.446701.78110HepG2SF3B1
TMEM138ENSG00000149483.7462.23530289.733000.673806.175505.35130HepG2SF3B4
TMEM138ENSG00000149483.7346.14840486.11110-0.489904.090903.26150HepG2SLBP
TMEM138ENSG00000149483.7481.93410302.428200.672106.326605.68290HepG2SRSF1
TMEM138ENSG00000149483.7404.32400500.55340-0.308001.840401.31560HepG2SRSF5
TMEM138ENSG00000149483.7314.29820246.049800.353101.939601.46170HepG2SRSF9
TMEM138ENSG00000149483.7829.15060536.699600.627408.736207.92490HepG2SSB
TMEM138ENSG00000149483.7765.67960569.254100.427604.743303.96800HepG2SUCLG1
TMEM138ENSG00000149483.7547.20970271.861101.0091013.5439012.44190HepG2TAF15
TMEM138ENSG00000149483.7421.93390249.774900.756306.837805.52940HepG2TIA1
TMEM138ENSG00000149483.7400.26930300.293600.414502.428901.95510HepG2TIAL1
TMEM138ENSG00000149483.7313.68660201.631400.637503.534102.67960HepG2UCHL5
TMEM138ENSG00000149483.7481.34710312.537900.622903.018001.96880HepG2UPF2
TMEM138ENSG00000149483.7455.03250274.758700.727707.325806.42800HepG2UTP3
TMEM138ENSG00000149483.7917.31360681.816000.427904.854604.13750K562AGGF1
TMEM138ENSG00000149483.7960.21050709.463300.436503.241302.53250K562AKAP8L
TMEM138ENSG00000149483.71878.502901386.426400.438104.226503.53080K562AQR
TMEM138ENSG00000149483.71160.16500744.403100.640105.665904.30410K562ATP5C1
TMEM138ENSG00000149483.7345.03140516.70790-0.582604.042802.72040K562CCAR1
TMEM138ENSG00000149483.7649.89620822.53240-0.339902.463001.71950K562CPSF6
TMEM138ENSG00000149483.72374.478001924.879200.302702.906201.90710K562CELF1
TMEM138ENSG00000149483.7938.31560763.415600.297502.677401.81950K562DKC1
TMEM138ENSG00000149483.7397.24000555.64440-0.484203.286101.81930K562DNAJC21
TMEM138ENSG00000149483.7562.48420755.37480-0.425402.857301.92890K562EFTUD2
TMEM138ENSG00000149483.7707.189501017.98070-0.525506.929605.86690K562EIF2S2
TMEM138ENSG00000149483.7735.71240548.719200.423003.793902.87180K562EIF3G
TMEM138ENSG00000149483.7422.02210701.29930-0.732707.676506.31030K562EIF4A3
TMEM138ENSG00000149483.7643.69480836.97710-0.378802.609001.77920K562FMR1
TMEM138ENSG00000149483.7516.55340709.44400-0.457803.074202.10490K562FTO
TMEM138ENSG00000149483.7400.82400687.68900-0.778808.401907.41210K562HNRNPC
TMEM138ENSG00000149483.71194.18940746.567500.677607.016304.97220K562HNRNPK
TMEM138ENSG00000149483.7810.148201054.99440-0.381003.860702.80160K562HNRNPU
TMEM138ENSG00000149483.7885.249601202.68000-0.442103.746102.82540K562HSPD1
TMEM138ENSG00000149483.7968.81300752.908000.363602.827901.99280K562KIF1C
TMEM138ENSG00000149483.7496.99380785.49260-0.660407.314505.92070K562MAGOH
TMEM138ENSG00000149483.7883.45010591.197200.579402.782701.89620K562NAA15
TMEM138ENSG00000149483.71135.47360967.934300.230202.338901.64760K562NSUN2
TMEM138ENSG00000149483.7649.65600883.30000-0.443202.988902.12500K562PCBP3
TMEM138ENSG00000149483.7520.96850677.52280-0.379102.813702.00450K562POLR2G
TMEM138ENSG00000149483.7483.15470735.06550-0.605404.787503.80530K562PRPF8
TMEM138ENSG00000149483.71071.758401707.91210-0.672308.345006.92270K562PUF60
TMEM138ENSG00000149483.71431.033201779.93460-0.314803.691502.58110K562PUM2
TMEM138ENSG00000149483.71101.85830703.572800.647107.140606.31410K562PUS1
TMEM138ENSG00000149483.7993.16690685.542400.534706.532905.64750K562RBM15
TMEM138ENSG00000149483.7570.15760748.77960-0.393202.195601.47160K562RPS19
TMEM138ENSG00000149483.7451.61560669.70460-0.568402.848601.83040K562RPS3
TMEM138ENSG00000149483.7528.28710751.60940-0.508702.768201.44220K562RRP9
TMEM138ENSG00000149483.71204.42890955.085900.334503.382102.48490K562SF3A3
TMEM138ENSG00000149483.7515.33160748.08520-0.537704.946304.00360K562SRSF1
TMEM138ENSG00000149483.7494.27070711.76050-0.526103.443002.29640K562SUPV3L1
TMEM138ENSG00000149483.7843.470101026.32030-0.283102.732102.01760K562UPF1
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for TMEM138 is not available on ENCORE database.





11 RBPs can affect the splicing of TMEM138 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SETMEM138ENSG00000149483.7chr11+6113487861134997611335896113368861135394611354700.108000.001240.02676includedK562U2AF1
SETMEM138ENSG00000149483.7chr11+6113487861134997611335896113368861135394611354700.135000.000810.01684includedK562U2AF2
SETMEM138ENSG00000149483.7chr11+611319046113205061131723611317876113351661134029-0.691000.000320.05693excludedK562EIF3G
A5SSTMEM138ENSG00000149483.7chr11+6113194761132084611319476113199061133516611340290.053000.000020.00051longerK562AQR
RITMEM138ENSG00000149483.7chr11+611317236113199061131723611317876113190461131990-0.262000.001990.01390excludedK562PUS1
RITMEM138ENSG00000149483.7chr11+611317236113199061131723611317876113190461131990-0.285000.000160.00280excludedK562AGGF1
RITMEM138ENSG00000149483.7chr11+611317236113199061131723611317876113190461131990-0.204000.002680.02594excludedK562AKAP8L
RITMEM138ENSG00000149483.7chr11+611317236113199061131723611317876113190461131990-0.312000.000000.00012excludedK562RBM15
RITMEM138ENSG00000149483.7chr11+611317236113199061131723611317876113190461131990-0.294000.000090.00187excludedK562UTP18
RITMEM138ENSG00000149483.7chr11+6113172361131990611317236113178761131904611319900.106000.003220.01935includedK562AQR
RITMEM138ENSG00000149483.7chr11+6113172361131990611317236113178761131904611319900.208000.000020.00107includedK562PTBP1
RITMEM138ENSG00000149483.7chr11+6113172361131990611317236113178761131904611319900.266000.000070.00217includedK562FXR1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for TMEM138 is not avaliable on ENCORE database.