SRBD1

General Information

Gene Name       : SRBD1
Gene ID             : ENSG00000068784.12
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: SRBD1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878SRBD1ENSG00000068784.1221.7315.2418.48ENCSR000AEF
HepG2SRBD1ENSG00000068784.129.4516.2212.83ENCSR985KAT
K562SRBD1ENSG00000068784.129.0010.459.72ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  
  GeneName    Cell_Line    Method    Exp_ID    Control_ID    Sample_reps    Control_reps    KD%    Status    Project    Note  
SRBD1K562CRISPRBGKcLV33-71,BGKcLV33-72BGKcLV33-1,BGKcLV33-2band unclear,NotSatisfiedENCODE4
SRBD1K562CRISPRBGKcLV33-75,BGKcLV33-76BGKcLV33-1,BGKcLV33-20.0,0.0NotSatisfiedENCODE4
SRBD1K562CRISPRBGKcLV35-73,BGKcLV35-74BGKcLV35-1,BGKcLV35-2too many bands,NotSatisfiedENCORE2
SRBD1HepG2CRISPRBGHcLV31-71,BGHcLV31-72BGHcLV31-1,BGHcLV31-20.0,0.0NotSatisfiedENCODE4
SRBD1HepG2CRISPRBGHcLV34-59,BGHcLV34-60BGHcLV34-1,BGHcLV34-2too many bands ,NotSatisfiedENCORE2


  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for SRBD1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • SRBD1 RNA is bound by 20 proteins.  







eCLIP assay for SRBD1 is not avaliable on ENCORE database.





20 proteins are bound to SRBD1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr24561589745615990-3'-UTR,intron-Distal,intron-Proximal,polyA_site3.155633.78871K562IGF2BP1
chr24561608645616148-3'-UTR,intron-Distal,intron-Proximal4.258623.98488K562TIA1
chr24583829245838418-5'-UTR,intron-Distal,intron-Proximal3.744423.07217HepG2NCBP2
chr24582693445826974-CDS,intron-Distal3.593114.09885HepG2BCLAF1
chr24577395745774008-CDS,intron-Distal,intron-Proximal3.038675.62171K562AQR
chr24580713645807153-CDS,intron-Distal,intron-Proximal3.754074.76554HepG2BCLAF1
chr24578076845780805-CDS,intron-Distal3.583553.57857HepG2BCLAF1
chr24582919945829210-CDS,intron-Distal3.067876.34055HepG2PPIG
chr24564553145645595-CDS,intron-Distal,intron-Proximal3.241323.12941K562UCHL5
chr24583249945832520-CDS,intron-Distal,intron-Proximal4.3667512.72422K562ZNF622
chr24577380045773896-CDS,intron-Distal,intron-Proximal4.975045.01842HepG2PRPF8
chr24582920045829224-CDS,intron-Distal,intron-Proximal3.735556.06436HepG2BCLAF1
chr24581287445812911-CDS,intron-Distal4.042326.22576HepG2BCLAF1
chr24582921345829223-CDS,intron-Distal,intron-Proximal3.9964312.57116K562ZNF622
chr24583252045832549-CDS,intron-Distal3.889936.14226K562ZNF622
chr24582659645826721-CDS,intron-Distal4.741285.35719HepG2GRWD1
chr24582658745826714-CDS,intron-Distal,intron-Proximal4.534778.58706K562UCHL5
chr24583249945832513-CDS,intron-Distal,intron-Proximal3.124545.21025HepG2PPIG
chr24582912145829189-CDS,intron-Distal3.863099.74534HepG2BCLAF1
chr24577382145773883-CDS,intron-Distal,intron-Proximal4.281204.22101K562PRPF8
chr24583254945832580-CDS,intron-Distal3.592686.55026K562ZNF622
chr24582664045826715-CDS,intron-Distal5.392079.22532K562ZNF622
chr24580176345801780-CDS,intron-Distal,intron-Proximal4.636094.34038HepG2BCLAF1
chr24582904145829065-CDS,intron-Distal,intron-Proximal3.292393.07653K562ZNF622
chr24582920145829208-CDS,intron-Distal3.587699.00464K562ZNF622
chr24580710445807129-CDS,intron-Distal4.176663.02457HepG2BCLAF1
chr24582661145826717-CDS,intron-Distal3.946775.20093K562DDX24
chr24582660345826800-CDS,intron-Distal4.8035821.21122HepG2BCLAF1
chr24582671445826792-CDS,intron-Distal3.014843.11583K562UCHL5
chr24582903745829090-CDS,intron-Distal,intron-Proximal3.552063.95937K562UCHL5
chr24582918945829225-CDS,intron-Distal,intron-Proximal3.099063.84837K562GRWD1
chr24582659645826640-CDS,intron-Distal4.745185.59615K562ZNF622
chr24580883145808861-CDS,intron-Distal,intron-Proximal4.872826.37937HepG2BCLAF1
chr24577354745773644-intron-Distal3.805263.42844K562KHSRP
chr24575579345755942-intron-Distal3.680775.42643HepG2MATR3
chr24573670845736816-intron-Distal3.840964.00200K562EIF4G2
chr24575113545751183-intron-Distal4.164773.59917K562EXOSC5
chr24579095345790992-intron-Distal3.884933.54147K562HNRNPM
chr24575577245755869-intron-Distal4.875787.45191HepG2PTBP1
chr24563292145633044-intron-Distal3.936825.03657K562PTBP1
chr24573415445734208-intron-Distal4.313545.84425HepG2CSTF2
chr24567036045670460-intron-Distal3.594575.78896K562PTBP1
chr24576852545768626-intron-Distal3.967557.67451HepG2LSM11
chr24563687345636996-intron-Distal3.823163.25538K562KHSRP
chr24575092745750988-intron-Distal3.214543.43875K562EXOSC5
chr24579096245791045-intron-Distal4.961537.71312K562EXOSC5
chr24567035745670454-intron-Distal3.253824.30137HepG2PTBP1
chr24565737045657425-intron-Distal4.155043.30696K562EXOSC5
chr24579066345790732-intron-Distal3.444253.43829K562EXOSC5
chr24575578045755846-intron-Distal3.294513.71597K562MATR3
chr24576850245768637-intron-Distal5.179159.95808K562LSM11
chr24577452745774658-intron-Distal,intron-Proximal5.208595.69951K562AQR
chr24582402045824144-intron-Distal5.751028.04355K562EIF4G2
chr24579095545791000-intron-Distal4.052383.34098HepG2HNRNPM
chr24575578945755901-intron-Distal4.218855.16181K562PTBP1
chr24567053345670637-intron-Distal3.926323.50357HepG2QKI
chr24576497945765047-intron-Distal4.208003.27829HepG2MATR3
chr24567501345675136-intron-Distal3.023835.34873K562KHSRP
chr24573420845734233-intron-Distal4.007494.64911HepG2CSTF2
chr24570571345705848-intron-Distal4.444135.68841K562KHSRP
chr24563293545633038-intron-Distal3.625824.81278HepG2PTBP1
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for SRBD1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for SRBD1 is not available on ENCORE database.

  • 93 RBPs can affect the levels of SRBD1.  








The Knockdown/knockout RNA-Seq assay for SRBD1 is not available on ENCORE database.





93 RBPs can affect the gene expression of SRBD1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
SRBD1ENSG00000068784.8783.78550533.414700.555103.547602.95480HepG2AKAP1
SRBD1ENSG00000068784.8350.56410824.22460-1.2334026.9665025.21770HepG2AUH
SRBD1ENSG00000068784.8390.83420542.88540-0.474102.137401.31730HepG2BCCIP
SRBD1ENSG00000068784.8266.74040471.75650-0.822605.643904.40760HepG2BCLAF1
SRBD1ENSG00000068784.8398.82220751.73850-0.9145010.870909.78650HepG2BOP1
SRBD1ENSG00000068784.8569.95590715.76980-0.328602.285601.57910HepG2CALR
SRBD1ENSG00000068784.8163.96720438.65690-1.4197023.2623021.75560HepG2CKAP4
SRBD1ENSG00000068784.8331.33850202.896400.707503.092702.28050HepG2CNOT7
SRBD1ENSG00000068784.8517.02680658.67090-0.349302.792802.14760HepG2CELF1
SRBD1ENSG00000068784.8373.59770533.75270-0.514702.461401.72750HepG2DDX55
SRBD1ENSG00000068784.8435.33350783.70100-0.848205.050503.74240HepG2DDX59
SRBD1ENSG00000068784.8344.89700531.86670-0.624904.740503.43840HepG2DDX5
SRBD1ENSG00000068784.8237.01840438.92680-0.889006.229905.33260HepG2DDX6
SRBD1ENSG00000068784.8345.32340506.62470-0.553004.043302.87300HepG2DHX30
SRBD1ENSG00000068784.8332.41580525.27310-0.660106.713305.65460HepG2DNAJC21
SRBD1ENSG00000068784.8367.41060520.63110-0.502905.001304.16550HepG2DNAJC2
SRBD1ENSG00000068784.8504.75760698.72050-0.469104.804503.75130HepG2EIF4G1
SRBD1ENSG00000068784.8507.02250669.33610-0.400702.590601.80140HepG2EIF4G2
SRBD1ENSG00000068784.8605.90190946.33300-0.643309.217008.22600HepG2ETF1
SRBD1ENSG00000068784.8313.91160428.74020-0.449702.738401.90680HepG2EWSR1
SRBD1ENSG00000068784.8384.44290691.31990-0.846603.436602.30060HepG2FTO
SRBD1ENSG00000068784.8617.83980470.484300.393002.112901.50560HepG2FXR1
SRBD1ENSG00000068784.8253.71170436.45260-0.782605.493804.56960HepG2G3BP1
SRBD1ENSG00000068784.8550.30470782.32340-0.507503.340802.64170HepG2GPKOW
SRBD1ENSG00000068784.8313.30170589.86540-0.912809.208708.00300HepG2HNRNPC
SRBD1ENSG00000068784.8368.06770691.36830-0.909509.313408.09520HepG2HNRNPF
SRBD1ENSG00000068784.8427.12910645.19720-0.595107.654006.58260HepG2HNRNPL
SRBD1ENSG00000068784.8409.83280680.81120-0.732205.973904.95170HepG2IGF2BP1
SRBD1ENSG00000068784.8292.73090598.54470-1.0319019.5395017.79530HepG2ILF2
SRBD1ENSG00000068784.8554.53360761.42110-0.457402.277001.40330HepG2MTPAP
SRBD1ENSG00000068784.8469.50100702.32180-0.581006.230305.08920HepG2NOL12
SRBD1ENSG00000068784.8280.95350431.43310-0.618803.834602.99580HepG2PABPC4
SRBD1ENSG00000068784.8510.33900382.545100.415703.266502.61700HepG2PCBP1
SRBD1ENSG00000068784.8422.80180522.63480-0.305801.931101.30710HepG2PPIL4
SRBD1ENSG00000068784.8471.30680606.14050-0.363002.811002.03280HepG2PRPF4
SRBD1ENSG00000068784.8222.05960411.83660-0.891106.120904.97080HepG2PRPF8
SRBD1ENSG00000068784.8293.48460670.41600-1.1918017.1733015.86190HepG2PUF60
SRBD1ENSG00000068784.8272.68520450.27860-0.723603.189202.43590HepG2RAVER1
SRBD1ENSG00000068784.8553.93070790.95660-0.513905.365604.70350HepG2RBM22
SRBD1ENSG00000068784.8724.58330433.204400.742009.617108.71840HepG2NELFE
SRBD1ENSG00000068784.8566.01310403.482800.488204.250803.50880HepG2RECQL
SRBD1ENSG00000068784.8381.11520744.61040-0.966308.218107.13980HepG2RPLP0
SRBD1ENSG00000068784.8164.93150407.40050-1.3046010.802509.40450HepG2RRP9
SRBD1ENSG00000068784.8361.99330738.97210-1.0296012.6830011.28200HepG2SF3B1
SRBD1ENSG00000068784.8512.67780642.79620-0.326302.765202.06370HepG2SLBP
SRBD1ENSG00000068784.8478.73820822.23610-0.780305.070604.00170HepG2SNRNP70
SRBD1ENSG00000068784.8366.65450893.35160-1.2848031.5719030.36010HepG2SRFBP1
SRBD1ENSG00000068784.8979.75890423.007001.2116028.6698027.50070HepG2SRSF1
SRBD1ENSG00000068784.8349.58800679.20890-0.9582010.436609.23440HepG2SRSF7
SRBD1ENSG00000068784.8581.18730775.63240-0.416404.429603.81210HepG2SSB
SRBD1ENSG00000068784.8903.42660752.801400.263002.238601.66810HepG2SUCLG1
SRBD1ENSG00000068784.8434.25870291.275700.576102.900901.54030HepG2SUGP2
SRBD1ENSG00000068784.8381.77550531.36860-0.477002.144801.53930HepG2SUPV3L1
SRBD1ENSG00000068784.8554.04260380.231100.543004.698303.99870HepG2TAF15
SRBD1ENSG00000068784.8417.38520727.69080-0.801908.246507.08310HepG2TARDBP
SRBD1ENSG00000068784.8253.23600356.17360-0.492102.256901.34910HepG2TFIP11
SRBD1ENSG00000068784.8355.65100569.37960-0.678906.885206.16150HepG2TIAL1
SRBD1ENSG00000068784.8366.55880574.46460-0.648207.913307.03710HepG2TRIM56
SRBD1ENSG00000068784.8188.52850313.91350-0.735604.279103.33430HepG2UCHL5
SRBD1ENSG00000068784.8403.27380512.51290-0.345802.474601.80810HepG2UPF1
SRBD1ENSG00000068784.8319.95970486.63940-0.605002.581601.61480HepG2UPF2
SRBD1ENSG00000068784.8837.08770495.143800.757405.499004.03600HepG2XRCC6
SRBD1ENSG00000068784.8358.22720523.07330-0.546102.954502.20500HepG2XRN2
SRBD1ENSG00000068784.8431.82640598.16220-0.470104.648703.81500HepG2ZC3H8
SRBD1ENSG00000068784.8197.78710563.66490-1.5109032.3285030.98690HepG2ZNF622
SRBD1ENSG00000068784.8586.66710871.92200-0.571707.250206.39500K562AGGF1
SRBD1ENSG00000068784.8703.14340907.27450-0.367702.590001.95710K562AKAP8L
SRBD1ENSG00000068784.8696.42990946.22990-0.442203.301902.67200K562AQR
SRBD1ENSG00000068784.8420.08780544.04200-0.373002.747801.78980K562BCLAF1
SRBD1ENSG00000068784.8526.59680758.40300-0.526303.740302.03440K562BUD13
SRBD1ENSG00000068784.8838.407901041.99410-0.313602.415601.32780K562CCDC124
SRBD1ENSG00000068784.8515.91230649.94370-0.333202.012801.33510K562CPSF6
SRBD1ENSG00000068784.8630.27620458.612800.458602.545601.32390K562EEF2
SRBD1ENSG00000068784.8208.01520443.14260-1.0911010.236008.37090K562EFTUD2
SRBD1ENSG00000068784.8526.97490698.16630-0.405802.868902.13930K562EIF2S2
SRBD1ENSG00000068784.8302.18320474.52640-0.651103.972502.70410K562EIF3D
SRBD1ENSG00000068784.8438.90370621.05050-0.500804.539503.53130K562EIF3G
SRBD1ENSG00000068784.8605.91790782.65770-0.369302.503301.69760K562FIP1L1
SRBD1ENSG00000068784.8408.98350560.54830-0.454802.633201.74310K562FTO
SRBD1ENSG00000068784.8793.01900598.258600.406502.100501.49610K562G3BP2
SRBD1ENSG00000068784.8592.57910930.47190-0.651004.146903.22470K562GRSF1
SRBD1ENSG00000068784.8254.82840521.41070-1.032908.358607.37200K562HNRNPC
SRBD1ENSG00000068784.8531.46090743.63410-0.484602.909501.84970K562IGF2BP2
SRBD1ENSG00000068784.8362.88060529.88050-0.546202.822701.87850K562KRR1
SRBD1ENSG00000068784.8617.42830781.71210-0.340402.315501.54220K562MAGOH
SRBD1ENSG00000068784.8421.21940605.70640-0.524004.227403.13070K562METAP2
SRBD1ENSG00000068784.8960.744301242.49450-0.371002.708501.59230K562MSI2
SRBD1ENSG00000068784.8658.54700791.36110-0.265002.426401.72340K562NSUN2
SRBD1ENSG00000068784.8402.22830695.56340-0.790208.390906.65050K562PCBP2
SRBD1ENSG00000068784.8669.02800888.43580-0.409203.078702.20680K562PPIG
SRBD1ENSG00000068784.8318.78660431.22740-0.435902.081401.42700K562PRPF8
SRBD1ENSG00000068784.8522.53430759.46870-0.539505.355604.45830K562PTBP1
SRBD1ENSG00000068784.8960.610701271.84320-0.404903.682802.74400K562PUF60
SRBD1ENSG00000068784.81084.049601325.47780-0.290102.788101.82580K562PUM2
SRBD1ENSG00000068784.8603.25220899.76620-0.576805.428404.70040K562PUS1
SRBD1ENSG00000068784.8532.08530728.33910-0.453003.454002.50990K562RBM22
SRBD1ENSG00000068784.8432.11250590.18240-0.449802.449301.53810K562SF3B1
SRBD1ENSG00000068784.8411.33690622.06670-0.596705.902904.61930K562SF3B4
SRBD1ENSG00000068784.8600.17780744.51210-0.310901.995601.38410K562SRSF1
SRBD1ENSG00000068784.8693.70630939.28620-0.437203.110701.77160K562STAU1
SRBD1ENSG00000068784.8479.01600753.53880-0.653606.046804.97170K562TARDBP
SRBD1ENSG00000068784.8718.49390960.32500-0.418502.533301.39000K562UTP3
SRBD1ENSG00000068784.8842.022901065.95330-0.340202.563801.73940K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for SRBD1 is not available on ENCORE database.





4 RBPs can affect the splicing of SRBD1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SESRBD1ENSG00000068784.8chr2-4577345545773515457153784571547045773870457739780.162000.004120.03966includedK562AQR
SESRBD1ENSG00000068784.8chr2-457041314570421445646926456470334571537845715470-0.095000.010560.08489excludedK562AQR
SESRBD1ENSG00000068784.8chr2-458127464581291345808831458089494582658745826974-0.164000.004090.05340excludedK562PUS1
A3SSSRBD1ENSG00000068784.8chr2-4578076145780897457807614578086945789791457899190.103000.004760.02767longerK562AQR
A3SSSRBD1ENSG00000068784.8chr2-4582904145829246458290414582922245832500458325800.138000.000040.00036longerK562AQR
A3SSSRBD1ENSG00000068784.8chr2-4577387045774033457738704577397845774660457747510.214000.000000.00000longerK562AQR
A3SSSRBD1ENSG00000068784.8chr2-4564025245640489456402524564043245645503456456800.051000.000600.00437longerK562AQR
MXESRBD1ENSG00000068784.8chr2-45704131457042144571537845715470456469264564703345773870457739780.108000.009300.083561includedK562DROSHA
MXESRBD1ENSG00000068784.8chr2-45715378457154704577345545773515457041314570421445773870457739780.224000.005740.040451includedK562AQR
MXESRBD1ENSG00000068784.8chr2-45715378457154704577345545773499457041314570421445773870457739780.264000.003500.026691includedK562AQR
MXESRBD1ENSG00000068784.8chr2-45715378457155154577345545773499457041314570421445773870457739780.498000.000230.061561includedK562MTPAP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for SRBD1 is not avaliable on ENCORE database.