SMYD5

General Information

Gene Name       : SMYD5
Gene ID             : ENSG00000135632.11
Essential Gene : No

Functions

Localization

Domains (AlphaFold: SMYD5)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878SMYD5ENSG00000135632.1118.8824.0421.46ENCSR000AEF
HepG2SMYD5ENSG00000135632.1164.2059.0361.62ENCSR985KAT
K562SMYD5ENSG00000135632.1136.0338.2337.13ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for SMYD5 is not avaliable on ENCORE database.



Proteins bound to RNA
  • SMYD5 RNA is bound by 16 proteins.  







eCLIP assay for SMYD5 is not avaliable on ENCORE database.





16 proteins are bound to SMYD5 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr27345371773453768+3'-UTR5.4499612.12236HepG2AKAP1
chr27345337373453442+3'-UTR5.6405012.73103HepG2UPF1
chr27345318973453275+3'-UTR3.692749.58774K562UPF1
chr27345347173453656+3'-UTR7.0722432.64820K562UPF1
chr27345306373453136+3'-UTR,CDS4.114773.18535HepG2LSM11
chr27345426973454309+3'-UTR4.163528.23922HepG2AKAP1
chr27345412173454231+3'-UTR5.168105.84761K562FAM120A
chr27345345573453541+3'-UTR6.6357226.23299HepG2AKAP1
chr27345020273450235+3'-UTR,CDS,intron-Proximal3.268754.51003HepG2PPIG
chr27345316473453222+3'-UTR5.2322717.45285HepG2AKAP1
chr27345338173453448+3'-UTR6.2275717.55229HepG2AKAP1
chr27345415473454208+3'-UTR3.9949910.31199K562UPF1
chr27345317373453293+3'-UTR6.7289430.18006HepG2UPF1
chr27345392173453976+3'-UTR3.096033.51117HepG2LSM11
chr27345394673453977+3'-UTR4.868457.01394HepG2AKAP1
chr27345316673453243+3'-UTR3.590315.35253HepG2LSM11
chr27345307973453144+3'-UTR5.117756.81418HepG2UPF1
chr27345322273453300+3'-UTR5.4922823.35409HepG2AKAP1
chr27345381773453897+3'-UTR6.0081715.10618HepG2AKAP1
chr27345345573453544+3'-UTR6.6483026.85931HepG2UPF1
chr27345384573453895+3'-UTR5.200248.87118HepG2UPF1
chr27345354473453648+3'-UTR6.6934028.67046HepG2UPF1
chr27344988873449932+3'-UTR,CDS3.070593.21309HepG2GRWD1
chr27345404073454076+3'-UTR4.303573.12485K562AKAP1
chr27345340273453422+3'-UTR3.837854.82552K562UPF1
chr27345393273454000+3'-UTR3.913856.84689K562UPF1
chr27345330073453371+3'-UTR5.0481815.57311HepG2AKAP1
chr27345354173453597+3'-UTR5.7771013.42494HepG2AKAP1
chr27345403973454091+3'-UTR3.804447.13820K562UPF1
chr27345383373453873+3'-UTR5.195967.35154K562UPF1
chr27345348173453538+3'-UTR4.485935.14276HepG2NKRF
chr27344990573449944+3'-UTR,CDS3.663954.22917HepG2PPIG
chr27345359773453661+3'-UTR5.8303013.70814HepG2AKAP1
chr27345409673454154+3'-UTR4.6242313.44564K562UPF1
chr27345304673453142+3'-UTR,CDS5.0891014.94017K562UPF1
chr27345370473453791+3'-UTR5.1702414.77591K562UPF1
chr27344139373441460+5'-UTR,CDS4.194923.08493K562DDX3X
chr27344141373441493+CDS,intron-Proximal3.481074.50631HepG2DDX3X
chr27345112273451172+CDS,intron-Proximal3.432395.43815HepG2PRPF8
chr27344146073441491+CDS,intron-Proximal4.802674.11950K562DDX3X
chr27345296373453035+CDS3.596205.14242HepG2G3BP1
chr27345276273452814+CDS3.159623.87559K562YBX3
chr27345064873450712+CDS,intron-Proximal4.065465.90868HepG2PRPF8
chr27344186773441927+CDS,intron-Distal,intron-Proximal3.372686.50485HepG2SUGP2
chr27344147573441537+CDS,intron-Proximal3.5804813.29488HepG2PRPF8
chr27345276673452808+CDS4.229344.25576HepG2PABPN1
chr27345296473452996+CDS5.391178.00788K562UPF1
chr27344244073442527+intron-Distal3.277113.11000HepG2HNRNPM
chr27344276573442853+intron-Distal4.020537.62792HepG2PTBP1
chr27344276273442872+intron-Distal3.689235.33544K562MATR3
chr27344262373442704+intron-Distal3.294017.08373HepG2SUGP2
chr27344202073442062+intron-Distal4.407455.35792HepG2SUGP2
chr27344260373442696+intron-Distal3.408193.04190HepG2MATR3
chr27344610573446186+intron-Proximal4.176913.85435K562PRPF8
chr27344609973446144+intron-Proximal4.100034.16174HepG2PRPF8
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for SMYD5 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for SMYD5 is not available on ENCORE database.

  • 80 RBPs can affect the levels of SMYD5.  








The Knockdown/knockout RNA-Seq assay for SMYD5 is not available on ENCORE database.





80 RBPs can affect the gene expression of SMYD5 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
SMYD5ENSG00000135632.7777.182901361.01540-0.808406.791104.19990HepG2AARS
SMYD5ENSG00000135632.71144.933001508.53730-0.397906.371105.52640HepG2ACO1
SMYD5ENSG00000135632.71902.722102724.22480-0.517804.397003.74720HepG2AKAP1
SMYD5ENSG00000135632.71160.237501486.93520-0.357902.423601.44600HepG2AKAP8
SMYD5ENSG00000135632.7888.768401164.24500-0.389503.643602.77500HepG2CALR
SMYD5ENSG00000135632.7825.639301112.67910-0.430501.985601.34240HepG2CNOT7
SMYD5ENSG00000135632.71492.031701905.54080-0.352902.691502.05590HepG2CELF1
SMYD5ENSG00000135632.71629.316601395.119600.223802.672701.85150HepG2DDX19B
SMYD5ENSG00000135632.72074.341902609.51210-0.331102.354901.77280HepG2DDX3X
SMYD5ENSG00000135632.7908.688301365.29880-0.587404.896603.90250HepG2DDX55
SMYD5ENSG00000135632.71436.396602241.83490-0.642206.271505.37120HepG2DDX6
SMYD5ENSG00000135632.71654.169402154.92190-0.381502.880802.27600HepG2EIF2S1
SMYD5ENSG00000135632.7911.319301269.84710-0.478604.196502.76650HepG2EIF2S2
SMYD5ENSG00000135632.7703.88940946.40300-0.427102.689201.79760HepG2EIF3D
SMYD5ENSG00000135632.71550.713602318.76220-0.580404.324503.47650HepG2EIF4B
SMYD5ENSG00000135632.71565.112001936.24010-0.307002.056801.34660HepG2EIF4G2
SMYD5ENSG00000135632.71107.791401690.76100-0.610003.314002.47860HepG2FIP1L1
SMYD5ENSG00000135632.71842.484902402.97850-0.383203.149002.41160HepG2FXR1
SMYD5ENSG00000135632.71160.669302228.95440-0.9414013.5151012.10660HepG2G3BP1
SMYD5ENSG00000135632.71524.977901248.152100.288902.101001.48690HepG2HNRNPC
SMYD5ENSG00000135632.71558.697802257.39290-0.534306.116405.10730HepG2HNRNPK
SMYD5ENSG00000135632.71070.540501239.89850-0.211901.976001.45450HepG2HNRNPU
SMYD5ENSG00000135632.71841.716302265.62640-0.298902.007401.42310HepG2IGF2BP2
SMYD5ENSG00000135632.71282.284702126.42250-0.729702.523701.58940HepG2IGF2BP3
SMYD5ENSG00000135632.71886.575002417.22300-0.357602.420701.82770HepG2MATR3
SMYD5ENSG00000135632.71082.216501367.86270-0.337902.968002.13090HepG2MSI2
SMYD5ENSG00000135632.71778.412402203.18150-0.309002.057801.42740HepG2PABPC4
SMYD5ENSG00000135632.7985.853801227.26210-0.316003.445602.51040HepG2PARN
SMYD5ENSG00000135632.71368.739502262.81830-0.7253020.6139019.20600HepG2PCBP1
SMYD5ENSG00000135632.71640.350701416.514300.211602.148401.45950HepG2PRPF4
SMYD5ENSG00000135632.7674.420201053.15370-0.643005.958204.82280HepG2PRPF8
SMYD5ENSG00000135632.71479.231902302.47080-0.6383015.6760014.57710HepG2PTBP1
SMYD5ENSG00000135632.71796.432301536.523600.225402.637502.03220HepG2PUS1
SMYD5ENSG00000135632.72030.320502493.69980-0.296603.419502.73500HepG2QKI
SMYD5ENSG00000135632.7797.323901283.28740-0.686604.019603.17650HepG2RAVER1
SMYD5ENSG00000135632.71352.176801622.97790-0.263402.373601.57330HepG2RBM15
SMYD5ENSG00000135632.71779.517102288.35630-0.362804.747204.11490HepG2RBM22
SMYD5ENSG00000135632.71591.207402263.16750-0.508206.963205.93320HepG2RBM25
SMYD5ENSG00000135632.71550.216202562.45510-0.7251020.8524019.63720HepG2NELFE
SMYD5ENSG00000135632.71769.556402386.53120-0.431508.237507.25860HepG2RECQL
SMYD5ENSG00000135632.7738.81060920.90450-0.317802.225701.66810HepG2RPS19
SMYD5ENSG00000135632.71309.190701104.172600.245602.647602.01470HepG2SAFB2
SMYD5ENSG00000135632.7632.87870924.25100-0.546404.529403.34170HepG2SERBP1
SMYD5ENSG00000135632.71058.67400822.115300.364702.663701.97160HepG2SF3B1
SMYD5ENSG00000135632.71559.785402397.22570-0.6200015.5964014.36810HepG2SF3B4
SMYD5ENSG00000135632.71746.018202584.63260-0.5659015.2166014.29080HepG2SRFBP1
SMYD5ENSG00000135632.71687.892002502.16160-0.5680014.3779013.47970HepG2SRSF1
SMYD5ENSG00000135632.71119.030101914.82030-0.775008.731807.70100HepG2SRSF5
SMYD5ENSG00000135632.71061.726402035.62190-0.9391032.9413031.44550HepG2SRSF9
SMYD5ENSG00000135632.72617.480102244.105200.221902.916202.39330HepG2SSB
SMYD5ENSG00000135632.7801.727701359.11540-0.761507.808606.76700HepG2SUPV3L1
SMYD5ENSG00000135632.71242.236202248.97650-0.8563022.9944021.59800HepG2TAF15
SMYD5ENSG00000135632.7694.55600910.95610-0.391302.327101.40610HepG2TFIP11
SMYD5ENSG00000135632.71177.207902005.68780-0.768708.451406.95940HepG2UBE2L3
SMYD5ENSG00000135632.7377.11160802.85860-1.0902014.1991012.51270HepG2UCHL5
SMYD5ENSG00000135632.71034.194901378.38200-0.414504.909304.02150HepG2UPF1
SMYD5ENSG00000135632.7961.789901411.45050-0.553403.620502.40750HepG2XRCC6
SMYD5ENSG00000135632.71198.964101397.90320-0.221502.322901.70060HepG2ZC3H8
SMYD5ENSG00000135632.7577.50040777.89860-0.429803.142601.87650K562AARS
SMYD5ENSG00000135632.71103.90700666.581900.7277013.5493012.39590K562AGGF1
SMYD5ENSG00000135632.71145.31800693.613600.723409.445908.15540K562AKAP8L
SMYD5ENSG00000135632.71062.17260727.776900.545307.383905.78740K562ATP5C1
SMYD5ENSG00000135632.7909.81330727.876200.321802.384101.41910K562DDX3X
SMYD5ENSG00000135632.71439.242601199.028100.263302.626701.98990K562DDX47
SMYD5ENSG00000135632.7930.91560737.958000.335002.981101.60670K562DDX6
SMYD5ENSG00000135632.7954.45160746.347000.354703.552802.54300K562DKC1
SMYD5ENSG00000135632.7937.390601384.26070-0.562409.244308.04660K562EIF2S2
SMYD5ENSG00000135632.7804.18700520.783300.626707.804006.47130K562EIF3G
SMYD5ENSG00000135632.71160.87120760.431500.610206.887305.60240K562EIF4A3
SMYD5ENSG00000135632.7512.47900739.03060-0.528103.781802.43500K562FKBP4
SMYD5ENSG00000135632.71010.03670790.813400.352903.404002.74260K562FXR1
SMYD5ENSG00000135632.7289.62640534.61660-0.884303.066902.31620K562G3BP2
SMYD5ENSG00000135632.7728.05730542.042900.425503.082102.24590K562GPKOW
SMYD5ENSG00000135632.71239.44120851.097400.542206.097305.24440K562HNRNPC
SMYD5ENSG00000135632.71357.918501083.537000.325502.718601.67440K562HNRNPL
SMYD5ENSG00000135632.71068.93910798.408400.420902.865001.91580K562HNRNPM
SMYD5ENSG00000135632.7966.50100714.038500.436702.710901.69730K562IGF2BP2
SMYD5ENSG00000135632.71113.47050750.272100.569506.601305.27540K562MAGOH
SMYD5ENSG00000135632.71120.95020748.726500.582106.957705.40930K562MATR3
SMYD5ENSG00000135632.71091.90490824.598000.405003.950002.83200K562MBNL1
SMYD5ENSG00000135632.7734.94400529.102100.474003.755002.72370K562METAP2
SMYD5ENSG00000135632.71177.11980982.607500.260502.540101.76400K562MTPAP
SMYD5ENSG00000135632.7868.29980577.985000.587103.864002.77390K562NAA15
SMYD5ENSG00000135632.7860.685601359.08970-0.659106.572205.28630K562PCBP3
SMYD5ENSG00000135632.7731.379201042.48380-0.511305.547304.41500K562POLR2G
SMYD5ENSG00000135632.71454.729601101.932400.400603.470102.53580K562PPIG
SMYD5ENSG00000135632.71128.70220728.947800.630708.385907.27090K562PTBP1
SMYD5ENSG00000135632.71140.25550687.839100.729107.554006.70280K562PUS1
SMYD5ENSG00000135632.7914.60150670.224800.448404.690303.93890K562RBM15
SMYD5ENSG00000135632.7986.98460527.679700.903303.749302.28240K562SF1
SMYD5ENSG00000135632.71394.224301045.616700.415004.598903.53410K562SYNCRIP
SMYD5ENSG00000135632.7592.00460918.52520-0.633705.958504.40270K562UCHL5
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for SMYD5 is not available on ENCORE database.





5 RBPs can affect the splicing of SMYD5 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SESMYD5ENSG00000135632.7chr2+734519937345208873450553734506607345275873452829-0.191000.000700.01525excludedHepG2U2AF1
SESMYD5ENSG00000135632.7chr2+734519937345208873451074734511317345275873452829-0.060000.006740.06716excludedHepG2U2AF2
SESMYD5ENSG00000135632.7chr2+7344625673446446734459887344609773447178734473180.121000.005670.07996includedK562U2AF2
A3SSSMYD5ENSG00000135632.7chr2+7344707973447318734471787344731873445988734460970.210000.001240.04522longerK562U2AF2
A3SSSMYD5ENSG00000135632.7chr2+734470797344731873447178734473187344586873446097-0.058000.000020.02407shorterK562PUM1
A5SSSMYD5ENSG00000135632.7chr2+7345016373450289734501637345023473450553734506600.054000.000130.00319longerK562AQR
MXESMYD5ENSG00000135632.7chr2+73451074734511317345199373452088734505537345066073452758734528290.133000.000430.011771includedHepG2SRSF1
MXESMYD5ENSG00000135632.7chr2+7345199373452088734527587345282973451074734511317345292373454365-0.130000.009160.058972includedK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for SMYD5 is not avaliable on ENCORE database.