SIL1

General Information

Gene Name       : SIL1
Gene ID             : ENSG00000120725.12
Essential Gene : No

Functions

Localization

Domains (AlphaFold: SIL1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878SIL1ENSG00000120725.1217.4817.7717.62ENCSR000AEF
HepG2SIL1ENSG00000120725.1221.5224.2022.86ENCSR985KAT
K562SIL1ENSG00000120725.1210.3212.2011.26ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for SIL1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • SIL1 RNA is bound by 19 proteins.  







eCLIP assay for SIL1 is not avaliable on ENCORE database.





19 proteins are bound to SIL1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr5138282521138282662-3'-UTR,intron-Distal,intron-Proximal4.311263.64119HepG2UPF1
chr5138282542138282683-3'-UTR,intron-Distal,intron-Proximal3.806393.08342HepG2AKAP1
chr5138282538138282657-3'-UTR,intron-Distal,intron-Proximal3.671144.50550K562UPF1
chr5138533956138533996-5'-UTR,intron-Distal,intron-Proximal4.3591710.28334HepG2DDX3X
chr5138533996138534038-5'-UTR,intron-Distal,intron-Proximal4.7164611.01276HepG2DDX3X
chr5138362609138362678-CDS,intron-Distal,intron-Proximal3.559403.90826K562ZNF622
chr5138463427138463462-CDS,intron-Distal,intron-Proximal4.038303.65750K562YBX3
chr5138283038138283135-CDS,intron-Distal4.275114.97391HepG2RPS3
chr5138378368138378404-CDS,intron-Distal,intron-Proximal3.978373.11168K562ZNF622
chr5138356889138356967-CDS,intron-Distal4.171453.24875K562SND1
chr5138378310138378368-CDS,intron-Distal,intron-Proximal3.522403.90826K562ZNF622
chr5138283056138283180-CDS,intron-Distal4.783954.67689HepG2PPIG
chr5138282999138283105-CDS,intron-Distal4.6910711.52585HepG2SND1
chr5138456719138456802-CDS,intron-Distal,intron-Proximal4.278324.07072K562UCHL5
chr5138283113138283161-CDS,intron-Distal3.544044.50521HepG2SND1
chr5138463429138463529-CDS,intron-Distal4.493767.63030HepG2DDX3X
chr5138287491138287568-CDS,intron-Distal,intron-Proximal4.093393.54264K562SND1
chr5138286877138287013-CDS,intron-Distal3.9743810.09138HepG2SND1
chr5138282817138282904-CDS,intron-Distal4.458174.95361HepG2SND1
chr5138356822138356887-CDS,intron-Distal,intron-Proximal6.057589.75034HepG2PRPF8
chr5138282978138283103-CDS,intron-Distal3.391204.50206K562SND1
chr5138282910138282999-CDS,intron-Distal4.741325.79199HepG2SND1
chr5138530014138530119-intron-Distal4.572816.10726HepG2SUGP2
chr5138287579138287674-intron-Distal,intron-Proximal5.200714.69961K562SF3B4
chr5138482004138482078-intron-Distal4.144516.22491K562AGGF1
chr5138533828138533914-intron-Distal5.815508.29453HepG2XPO5
chr5138288119138288194-intron-Distal3.189934.23271HepG2HNRNPM
chr5138340994138341103-intron-Distal3.822713.08967K562KHDRBS1
chr5138325208138325269-intron-Distal4.609563.91475K562PTBP1
chr5138288108138288199-intron-Distal4.732235.58025K562HNRNPM
chr5138511104138511201-intron-Distal4.096463.27946HepG2HNRNPM
chr5138481544138481588-intron-Distal4.297867.29348K562AGGF1
chr5138494098138494186-intron-Distal4.091593.84389HepG2SUGP2
chr5138325203138325279-intron-Distal3.184123.30286HepG2PTBP1
chr5138395699138395779-intron-Distal4.253574.05848HepG2QKI
chr5138335522138335582-intron-Distal3.989963.53509HepG2HLTF
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for SIL1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for SIL1 is not available on ENCORE database.

  • 94 RBPs can affect the levels of SIL1.  








The Knockdown/knockout RNA-Seq assay for SIL1 is not available on ENCORE database.





94 RBPs can affect the gene expression of SIL1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
SIL1ENSG00000120725.8772.18970473.104100.7067011.1226010.07490HepG2ACO1
SIL1ENSG00000120725.82195.09840559.161001.9728044.4195042.67000HepG2AKAP1
SIL1ENSG00000120725.8638.77560475.274400.426403.905303.00630HepG2AKAP8L
SIL1ENSG00000120725.8686.76910522.083900.395402.573501.99350HepG2BOP1
SIL1ENSG00000120725.8610.77450387.930500.654704.394203.44890HepG2CALR
SIL1ENSG00000120725.8479.33510308.336500.636402.995702.19610HepG2CNOT7
SIL1ENSG00000120725.8835.94550479.299800.802408.620407.46550HepG2CPSF6
SIL1ENSG00000120725.8645.99460486.323700.409502.777001.67060HepG2CPSF7
SIL1ENSG00000120725.81008.42920442.861401.1871029.4926027.86200HepG2CELF1
SIL1ENSG00000120725.8875.76820476.106700.8792019.1652017.54010HepG2DAZAP1
SIL1ENSG00000120725.8311.41890437.52450-0.490504.390903.37100HepG2DDX19B
SIL1ENSG00000120725.81217.59650535.631301.1846017.6221016.18820HepG2DDX3X
SIL1ENSG00000120725.8588.25680392.336200.584302.882102.09440HepG2DDX55
SIL1ENSG00000120725.8640.35590480.490200.414302.665501.67030HepG2DDX5
SIL1ENSG00000120725.8959.41110460.124701.0600012.1723010.98490HepG2DDX6
SIL1ENSG00000120725.8447.41140267.368400.742707.290006.19180HepG2DNAJC21
SIL1ENSG00000120725.8336.63060265.012300.345001.987601.41820HepG2DNAJC2
SIL1ENSG00000120725.8592.38850403.846200.552603.561702.52360HepG2EEF2
SIL1ENSG00000120725.8773.91520442.322700.807007.743206.78730HepG2EIF2S1
SIL1ENSG00000120725.8458.98370327.833200.485402.599101.71960HepG2EIF3D
SIL1ENSG00000120725.8675.36530488.815600.466302.726102.09140HepG2EIF4A3
SIL1ENSG00000120725.8602.79320450.003000.421602.846002.01980HepG2EIF4G2
SIL1ENSG00000120725.8372.02430511.56650-0.459502.749901.65940HepG2ESF1
SIL1ENSG00000120725.8484.26600864.52900-0.836109.652008.63850HepG2ETF1
SIL1ENSG00000120725.8440.31710293.001300.587504.572503.03660HepG2FAM120A
SIL1ENSG00000120725.8529.31150330.077000.681204.037002.69670HepG2FUS
SIL1ENSG00000120725.8447.39520306.077300.547602.975501.91830HepG2GNB2L1
SIL1ENSG00000120725.8570.83950437.593300.383403.040402.06700HepG2HNRNPA2B1
SIL1ENSG00000120725.8652.71800463.285600.494503.373002.60470HepG2HNRNPK
SIL1ENSG00000120725.8604.33450433.673100.478605.270404.36560HepG2HNRNPL
SIL1ENSG00000120725.8448.49090298.263600.588405.531104.69670HepG2HNRNPU
SIL1ENSG00000120725.8609.33850465.051100.389802.149901.54570HepG2IGF2BP2
SIL1ENSG00000120725.8436.77970293.978000.571103.100801.82350HepG2KHDRBS1
SIL1ENSG00000120725.8504.51450299.935500.750105.929904.28820HepG2LARP7
SIL1ENSG00000120725.8721.74260493.375900.548703.898103.12040HepG2MAGOH
SIL1ENSG00000120725.8379.07400253.893700.578203.185501.45040HepG2MARK2
SIL1ENSG00000120725.8680.94680496.135700.456702.569001.95890HepG2MATR3
SIL1ENSG00000120725.8536.39870343.107100.644502.745801.69810HepG2METAP2
SIL1ENSG00000120725.8647.50420482.607300.423902.931402.09940HepG2MSI2
SIL1ENSG00000120725.8770.92860507.821300.602204.516403.71650HepG2NCBP2
SIL1ENSG00000120725.8629.26290472.110600.414403.532702.67110HepG2NOL12
SIL1ENSG00000120725.8592.45700360.413700.717002.900901.78020HepG2NONO
SIL1ENSG00000120725.8476.03800304.759800.643303.826701.46830HepG2NUSAP1
SIL1ENSG00000120725.8527.72100281.875000.904605.285504.02970HepG2PABPC1
SIL1ENSG00000120725.8738.46970452.242400.707306.120505.05890HepG2PABPC4
SIL1ENSG00000120725.8461.65200295.227900.644906.116304.93460HepG2PARN
SIL1ENSG00000120725.8661.47080475.341000.476604.805404.04070HepG2PCBP1
SIL1ENSG00000120725.8354.02670266.027000.412202.431901.73670HepG2PPIL4
SIL1ENSG00000120725.8630.70340483.686700.382803.031202.46410HepG2PTBP1
SIL1ENSG00000120725.8852.71370478.455300.8336010.452209.45550HepG2PUM1
SIL1ENSG00000120725.8830.08010478.090100.795909.562508.35400HepG2PUM2
SIL1ENSG00000120725.8390.44490501.35730-0.360702.351101.77660HepG2RECQL
SIL1ENSG00000120725.8412.94580318.997300.372301.914901.39520HepG2RPS19
SIL1ENSG00000120725.8514.81910340.504000.596303.695802.44480HepG2RPS5
SIL1ENSG00000120725.8386.31620265.615900.540304.242403.47440HepG2SAFB2
SIL1ENSG00000120725.8374.80150513.20960-0.453402.717002.01670HepG2SF3B1
SIL1ENSG00000120725.8403.86960503.56340-0.318301.931901.42290HepG2SF3B4
SIL1ENSG00000120725.8601.92210432.195800.477805.206604.29330HepG2SLBP
SIL1ENSG00000120725.8458.85760309.751500.566805.373704.52770HepG2SMN1
SIL1ENSG00000120725.8592.09080308.008300.942707.776306.12970HepG2SMNDC1
SIL1ENSG00000120725.81064.88190571.036700.898903.506402.62190HepG2SNRNP70
SIL1ENSG00000120725.8606.19750816.08380-0.428903.685903.13310HepG2SRFBP1
SIL1ENSG00000120725.8395.54310525.61800-0.410202.996702.50940HepG2SRSF1
SIL1ENSG00000120725.8615.36240445.023500.467504.734803.95270HepG2SRSF5
SIL1ENSG00000120725.8693.99780506.088400.455405.179904.37440HepG2SUCLG1
SIL1ENSG00000120725.8694.74380402.650700.786909.114707.49000HepG2SUPT6H
SIL1ENSG00000120725.8341.19420472.46520-0.469603.287902.68430HepG2TAF15
SIL1ENSG00000120725.8661.26580505.389100.387702.357201.68100HepG2TARDBP
SIL1ENSG00000120725.8662.09800292.409901.1790023.0506021.62160HepG2TRIM56
SIL1ENSG00000120725.8636.01040440.348800.530303.040302.12010HepG2TUFM
SIL1ENSG00000120725.8886.21460466.129500.926808.883207.34980HepG2UBE2L3
SIL1ENSG00000120725.8619.64350450.547700.459704.519803.66310HepG2UPF1
SIL1ENSG00000120725.8273.59150384.42470-0.490702.805702.07640HepG2XRN2
SIL1ENSG00000120725.8881.42230495.515700.8308017.4754016.39520HepG2ZNF622
SIL1ENSG00000120725.8871.45200698.203000.319703.121402.52440K562AGGF1
SIL1ENSG00000120725.8463.54980314.757000.558405.008602.92730K562AKAP1
SIL1ENSG00000120725.8241.45450403.41870-0.740504.648703.92320K562AQR
SIL1ENSG00000120725.8947.30070762.330500.313302.242301.42820K562ATP5C1
SIL1ENSG00000120725.8377.40360273.222000.465902.552001.32360K562CIRBP
SIL1ENSG00000120725.8285.32500205.726000.471802.244001.53100K562CPSF6
SIL1ENSG00000120725.8192.37780126.902300.600102.499901.50340K562CSTF2
SIL1ENSG00000120725.8235.77690146.681600.684604.288902.62530K562DDX27
SIL1ENSG00000120725.8491.48440318.954200.623705.370503.85250K562DDX3X
SIL1ENSG00000120725.8356.85470168.766001.080203.537402.07440K562EEF2
SIL1ENSG00000120725.8476.83800219.744201.1176014.5969013.14300K562EIF2S2
SIL1ENSG00000120725.8412.46540536.35320-0.378902.853001.90020K562EIF4G2
SIL1ENSG00000120725.8183.48440346.55950-0.917408.083307.11690K562FXR1
SIL1ENSG00000120725.8476.12610292.795500.701405.125904.09370K562GRSF1
SIL1ENSG00000120725.8127.05190205.65280-0.694803.031802.40950K562HNRNPC
SIL1ENSG00000120725.8476.70500293.921500.697605.316404.23110K562HSPD1
SIL1ENSG00000120725.8395.96440254.944200.635103.455002.26220K562IGF2BP2
SIL1ENSG00000120725.8363.61440259.306000.487702.891501.66850K562IGF2BP3
SIL1ENSG00000120725.8918.02800738.054600.314702.322301.36600K562MAK16
SIL1ENSG00000120725.8160.75060238.37890-0.568402.604101.65580K562PCBP2
SIL1ENSG00000120725.8387.57040585.18390-0.594405.223504.10510K562PUF60
SIL1ENSG00000120725.81013.50240720.407000.492403.995203.36040K562PUS1
SIL1ENSG00000120725.8245.83620168.221500.547202.613601.65260K562RCC2
SIL1ENSG00000120725.8390.25480241.007200.695205.076703.57420K562SRSF5
SIL1ENSG00000120725.8180.56370245.61440-0.443902.004101.30580K562SYNCRIP
SIL1ENSG00000120725.8402.26590249.121200.691205.033503.87760K562TIA1
SIL1ENSG00000120725.8343.94590244.471700.492402.501001.47460K562TRA2A
SIL1ENSG00000120725.8298.45910188.403300.663603.554502.45770K562TRIM56
SIL1ENSG00000120725.8450.48690358.745300.328401.949101.33860K562UPF1
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for SIL1 is not available on ENCORE database.





6 RBPs can affect the splicing of SIL1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SESIL1ENSG00000120725.8chr5-138532129138532217138463427138463542138533957138533997-0.106000.000030.00139excludedHepG2HNRNPK
SESIL1ENSG00000120725.8chr5-138532129138532217138463427138463542138533957138534005-0.084000.000050.00636excludedHepG2AKAP1
SESIL1ENSG00000120725.8chr5-138532129138532217138463427138463542138533957138533997-0.092000.000180.01607excludedHepG2NCBP2
SESIL1ENSG00000120725.8chr5-1384636321384637411384634271384635421385339571385339930.652000.000730.01736includedK562U2AF1
SESIL1ENSG00000120725.8chr5-1384636321384637411384634271384635421385339571385339930.663000.000000.00014includedK562U2AF2
SESIL1ENSG00000120725.8chr5-138463632138463741138463427138463542138533957138533993-0.208000.000120.00749excludedK562PTBP1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for SIL1 is not avaliable on ENCORE database.