POLB

General Information

Gene Name : POLB
Gene ID : ENSG00000070501.11
Essential Gene : No

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: POLB)

Not Available

Antibody Validation

Not Avaiable

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	POLB	ENSG00000070501.11	33.77	30.78	32.28	ENCSR000AEF
HepG2	POLB	ENSG00000070501.11	18.10	35.70	26.90	ENCSR985KAT
K562	POLB	ENSG00000070501.11	43.17	43.75	43.46	ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.

eCLIP

No eCLIP experiment available

Antibody Validation

No Antibody Primary Validation image or Secondary image available

KD RNA-Seq

No KD RNA-Seq experiment available

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for POLB is not avaliable on ENCORE database.

Proteins bound to RNA

POLB RNA is bound by 6 proteins.

eCLIP assay for POLB is not avaliable on ENCORE database.

6 proteins are bound to POLB RNA:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr8	42220202	42220292	+	3'-UTR,CDS,intron-Distal,intron-Proximal	4.55968	5.17894	K562	PRPF8
chr8	42196006	42196173	+	5'-UTR,CDS,intron-Proximal	3.82938	6.09067	HepG2	NCBP2
chr8	42196022	42196084	+	5'-UTR	4.66002	4.66602	K562	DDX3X
chr8	42196165	42196251	+	5'-UTR,CDS,intron-Distal,intron-Proximal	4.69694	14.13178	HepG2	PRPF8
chr8	42202535	42202662	+	5'-UTR,CDS,intron-Distal,intron-Proximal	3.25291	3.67092	K562	PRPF8
chr8	42198097	42198172	+	intron-Distal	4.42555	4.40847	HepG2	PTBP1
chr8	42209660	42209752	+	intron-Distal	4.03752	3.50357	HepG2	QKI
chr8	42196232	42196290	+	intron-Distal,intron-Proximal	3.70487	5.29694	K562	EFTUD2
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

eCLIP assay for POLB is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for POLB is not available on ENCORE database.
61 RBPs can affect the levels of POLB.

The Knockdown/knockout RNA-Seq assay for POLB is not available on ENCORE database.

61 RBPs can affect the gene expression of POLB :

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
POLB	ENSG00000070501.7	609.14540	346.24030	0.81490	6.26370	4.91110	HepG2	ABCF1
POLB	ENSG00000070501.7	353.20830	252.78820	0.48250	2.48750	1.54090	HepG2	ADAR
POLB	ENSG00000070501.7	757.67530	465.47650	0.70280	5.21440	4.51290	HepG2	AKAP1
POLB	ENSG00000070501.7	437.70900	296.97800	0.55950	4.73030	3.74880	HepG2	AKAP8L
POLB	ENSG00000070501.7	585.68600	444.80380	0.39690	3.21800	2.48680	HepG2	AUH
POLB	ENSG00000070501.7	916.57910	365.92310	1.32460	20.41080	18.54390	HepG2	CIRBP
POLB	ENSG00000070501.7	387.55870	295.51850	0.39110	2.60230	1.95290	HepG2	CKAP4
POLB	ENSG00000070501.7	565.70350	469.40750	0.26910	1.91850	1.36440	HepG2	CELF1
POLB	ENSG00000070501.7	373.54310	273.38940	0.45020	3.37050	2.46110	HepG2	DDX19B
POLB	ENSG00000070501.7	557.45750	246.24150	1.17870	14.23560	12.83900	HepG2	DDX21
POLB	ENSG00000070501.7	568.30600	341.18120	0.73600	5.29930	3.58070	HepG2	DDX27
POLB	ENSG00000070501.7	713.57960	445.92890	0.67820	5.43990	4.58910	HepG2	DDX3X
POLB	ENSG00000070501.7	479.63600	321.38450	0.57750	2.92310	1.88570	HepG2	DDX5
POLB	ENSG00000070501.7	600.43250	282.81910	1.08600	16.82610	15.46790	HepG2	DKC1
POLB	ENSG00000070501.7	263.93760	368.24970	-0.48050	2.26750	1.72630	HepG2	EIF2S1
POLB	ENSG00000070501.7	344.68010	232.41460	0.56850	3.40470	2.22460	HepG2	EIF3G
POLB	ENSG00000070501.7	747.58410	407.00160	0.87710	8.14590	7.05350	HepG2	EIF4A3
POLB	ENSG00000070501.7	703.62470	396.19220	0.82850	5.90070	4.92360	HepG2	EIF4B
POLB	ENSG00000070501.7	626.58210	497.93090	0.33150	2.75560	1.92030	HepG2	EIF4G1
POLB	ENSG00000070501.7	739.70390	510.66830	0.53450	6.34410	5.49570	HepG2	ETF1
POLB	ENSG00000070501.7	429.11550	288.84050	0.57100	3.32780	2.41290	HepG2	EWSR1
POLB	ENSG00000070501.7	285.27220	185.07580	0.62410	3.17850	2.21020	HepG2	GEMIN5
POLB	ENSG00000070501.7	329.87080	459.62740	-0.47860	3.69730	2.92560	HepG2	HNRNPL
POLB	ENSG00000070501.7	551.94480	395.28240	0.48150	2.89280	2.25130	HepG2	HNRNPLL
POLB	ENSG00000070501.7	519.18140	387.18450	0.42310	2.31830	1.69450	HepG2	IGF2BP2
POLB	ENSG00000070501.7	545.42920	410.66190	0.40930	2.19260	1.60690	HepG2	MAGOH
POLB	ENSG00000070501.7	381.37500	283.03070	0.43020	2.36920	1.61750	HepG2	MSI2
POLB	ENSG00000070501.7	632.82560	477.68720	0.40560	1.81720	1.32100	HepG2	PUF60
POLB	ENSG00000070501.7	462.50730	301.10340	0.61910	6.11630	5.26450	HepG2	PUS1
POLB	ENSG00000070501.7	1005.82520	426.82960	1.23650	28.22160	26.91160	HepG2	RBM22
POLB	ENSG00000070501.7	255.81950	371.13110	-0.53680	3.14480	2.43080	HepG2	RBM25
POLB	ENSG00000070501.7	622.78530	420.22280	0.56750	5.66290	4.93220	HepG2	NELFE
POLB	ENSG00000070501.7	598.84250	475.62450	0.33230	2.21490	1.59480	HepG2	RPLP0
POLB	ENSG00000070501.7	279.10820	202.24300	0.46460	2.17580	1.62380	HepG2	RPS19
POLB	ENSG00000070501.7	517.01930	312.19790	0.72770	5.25360	4.17100	HepG2	RPS2
POLB	ENSG00000070501.7	420.60700	278.32190	0.59560	3.48310	2.61480	HepG2	RRP9
POLB	ENSG00000070501.7	327.88620	252.88300	0.37460	2.07830	1.50710	HepG2	SAFB2
POLB	ENSG00000070501.7	890.47980	354.07440	1.33040	15.85590	14.16390	HepG2	SF3A3
POLB	ENSG00000070501.7	687.18090	391.25470	0.81250	4.56800	3.67870	HepG2	SF3B1
POLB	ENSG00000070501.7	360.73730	458.10520	-0.34470	2.03930	1.41950	HepG2	SLBP
POLB	ENSG00000070501.7	441.26150	294.91030	0.58130	5.47100	4.61800	HepG2	SMN1
POLB	ENSG00000070501.7	784.21050	482.09790	0.70180	10.51130	9.70480	HepG2	SRFBP1
POLB	ENSG00000070501.7	708.02950	410.32610	0.78690	10.93290	10.12770	HepG2	SRSF1
POLB	ENSG00000070501.7	315.12650	433.86250	-0.46130	2.46110	1.80070	HepG2	SRSF7
POLB	ENSG00000070501.7	846.37600	418.59190	1.01570	21.56520	20.43030	HepG2	SSB
POLB	ENSG00000070501.7	486.89780	275.94340	0.81910	8.38400	7.59910	HepG2	TIAL1
POLB	ENSG00000070501.7	590.92420	299.12290	0.98210	9.68970	8.50010	HepG2	U2AF1
POLB	ENSG00000070501.7	395.34570	314.00920	0.33220	1.97720	1.37080	HepG2	UPF1
POLB	ENSG00000070501.7	481.18910	332.44550	0.53340	2.66990	1.68240	HepG2	UPF2
POLB	ENSG00000070501.7	506.72810	308.70640	0.71490	4.25450	2.95170	HepG2	XRCC6
POLB	ENSG00000070501.7	471.73690	345.35090	0.44980	3.85070	3.23400	HepG2	ZNF622
POLB	ENSG00000070501.7	1160.95790	950.45450	0.28850	2.60510	1.75970	K562	DKC1
POLB	ENSG00000070501.7	639.18150	783.29560	-0.29330	2.22600	1.57030	K562	EIF2S2
POLB	ENSG00000070501.7	646.60450	493.34630	0.39020	3.10480	2.46920	K562	FXR1
POLB	ENSG00000070501.7	1296.22300	1043.85450	0.31230	2.41860	1.70930	K562	GRSF1
POLB	ENSG00000070501.7	494.00350	720.95730	-0.54540	5.13180	3.68410	K562	HNRNPA1
POLB	ENSG00000070501.7	489.67700	611.56000	-0.32070	1.82990	1.33230	K562	HNRNPC
POLB	ENSG00000070501.7	410.86820	546.16400	-0.41070	2.53220	1.44660	K562	HNRNPF
POLB	ENSG00000070501.7	731.65660	511.25280	0.51700	3.49680	2.43830	K562	HNRNPM
POLB	ENSG00000070501.7	1123.57970	842.66770	0.41500	3.25970	2.39730	K562	HSPD1
POLB	ENSG00000070501.7	362.00670	500.34190	-0.46690	3.10290	2.04500	K562	RCC2
POLB	ENSG00000070501.7	703.93110	481.07710	0.54910	3.91200	2.93720	K562	RPS19
POLB	ENSG00000070501.7	436.25490	560.35830	-0.36120	2.12950	1.31500	K562	TRIM56
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for POLB is not available on ENCORE database.

20 RBPs can affect the splicing of POLB :

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	2ndExonStart	2ndExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP
SE	POLB	ENSG00000070501.7	chr8	+	42196529	42196587			42196122	42196203	42202470	42202537	0.25100	0.00000	0.00000	included	K562	SRSF1
SE	POLB	ENSG00000070501.7	chr8	+	42211934	42212039			42210036	42210086	42213033	42213085	-0.11400	0.00013	0.00393	excluded	K562	SRSF1
SE	POLB	ENSG00000070501.7	chr8	+	42206533	42206608			42202470	42202537	42213033	42213085	-0.24600	0.00008	0.00259	excluded	K562	SF3B4
SE	POLB	ENSG00000070501.7	chr8	+	42214837	42214910			42214686	42214741	42218812	42218883	-0.08500	0.00042	0.01030	excluded	K562	SF3B4
SE	POLB	ENSG00000070501.7	chr8	+	42196529	42196587			42196122	42196203	42202470	42202537	-0.31000	0.00000	0.00000	excluded	K562	SF3B4
SE	POLB	ENSG00000070501.7	chr8	+	42211934	42212039			42210036	42210086	42213033	42213085	0.21500	0.00075	0.03016	included	K562	PRPF8
SE	POLB	ENSG00000070501.7	chr8	+	42220129	42220216			42218812	42218883	42229080	42229326	-0.15000	0.00276	0.06764	excluded	K562	AKAP8L
SE	POLB	ENSG00000070501.7	chr8	+	42207524	42207583			42206556	42206608	42210036	42210086	-0.16300	0.00528	0.05543	excluded	HepG2	U2AF2
SE	POLB	ENSG00000070501.7	chr8	+	42196529	42196587			42196122	42196203	42202470	42202537	-0.26300	0.00850	0.08006	excluded	HepG2	U2AF2
SE	POLB	ENSG00000070501.7	chr8	+	42196529	42196587			42196122	42196203	42202470	42202537	0.25500	0.00054	0.03726	included	HepG2	AKAP1
SE	POLB	ENSG00000070501.7	chr8	+	42220129	42220216			42218812	42218883	42226788	42226815	-0.06000	0.01267	0.09783	excluded	K562	AQR
SE	POLB	ENSG00000070501.7	chr8	+	42196529	42196587			42196122	42196203	42202470	42202537	-0.19400	0.00011	0.00686	excluded	K562	FXR1
SE	POLB	ENSG00000070501.7	chr8	+	42196529	42196587			42195972	42196203	42202470	42202537	-0.15900	0.00001	0.00024	excluded	K562	PUS1
SE	POLB	ENSG00000070501.7	chr8	+	42211934	42212039			42210036	42210086	42213033	42213085	0.14000	0.00052	0.02816	included	HepG2	SFPQ
SE	POLB	ENSG00000070501.7	chr8	+	42218613	42218720			42214837	42214910	42218812	42218883	0.14300	0.00005	0.00682	included	HepG2	FTO
SE	POLB	ENSG00000070501.7	chr8	+	42206533	42206608			42202470	42202537	42213033	42213085	-0.25800	0.00007	0.00254	excluded	K562	U2AF1
SE	POLB	ENSG00000070501.7	chr8	+	42196529	42196587			42196122	42196203	42202470	42202537	0.19400	0.00033	0.06532	included	K562	SBDS
SE	POLB	ENSG00000070501.7	chr8	+	42218613	42218720			42214837	42214910	42218812	42218883	0.06500	0.00006	0.00262	included	HepG2	SRSF1
SE	POLB	ENSG00000070501.7	chr8	+	42196529	42196587			42196122	42196203	42202470	42202537	0.20200	0.00023	0.00766	included	HepG2	SRSF1
SE	POLB	ENSG00000070501.7	chr8	+	42211934	42212039			42210036	42210086	42213033	42213085	-0.13400	0.00003	0.00117	excluded	HepG2	SRSF1
SE	POLB	ENSG00000070501.7	chr8	+	42196529	42196587			42196122	42196203	42202470	42202537	-0.30200	0.00000	0.00002	excluded	HepG2	SF3A3
SE	POLB	ENSG00000070501.7	chr8	+	42220129	42220216			42218815	42218883	42226788	42226847	0.15800	0.00023	0.02799	included	HepG2	SUPV3L1
SE	POLB	ENSG00000070501.7	chr8	+	42220129	42220216			42218815	42218883	42229080	42229326	-0.16300	0.00102	0.03471	excluded	K562	UTP18
SE	POLB	ENSG00000070501.7	chr8	+	42211934	42212039			42210036	42210086	42213033	42213085	0.38100	0.00000	0.00000	included	K562	TARDBP
SE	POLB	ENSG00000070501.7	chr8	+	42220129	42220216			42218815	42218883	42229080	42229326	-0.20900	0.00006	0.00282	excluded	K562	RBM15
SE	POLB	ENSG00000070501.7	chr8	+	42196529	42196587			42196122	42196203	42202470	42202537	-0.10800	0.00221	0.04945	excluded	K562	RBM15
SE	POLB	ENSG00000070501.7	chr8	+	42220129	42220216			42218815	42218883	42229080	42229326	-0.24100	0.00000	0.00027	excluded	K562	AGGF1
A3SS	POLB	ENSG00000070501.7	chr8	+	42207505	42207583			42207524	42207583	42206533	42206608	0.07500	0.00037	0.00287	longer	K562	AQR
MXE	POLB	ENSG00000070501.7	chr8	+	42202470	42202537	42210036	42210086	42196529	42196587	42213033	42213085	-0.12700	0.00025	0.00693	2included	K562	PUS1
MXE	POLB	ENSG00000070501.7	chr8	+	42196529	42196587	42202470	42202537	42196011	42196203	42229080	42229326	-0.16100	0.00000	0.00007	2included	K562	PUS1
MXE	POLB	ENSG00000070501.7	chr8	+	42210036	42210086	42211934	42212039	42207524	42207583	42213033	42213085	0.11600	0.00067	0.08447	1included	K562	UTP3
MXE	POLB	ENSG00000070501.7	chr8	+	42202470	42202537	42213033	42213085	42195976	42196203	42214686	42214741	0.16000	0.00133	0.01165	1included	K562	AQR
MXE	POLB	ENSG00000070501.7	chr8	+	42202470	42202537	42227366	42227506	42196011	42196203	42229080	42229326	0.12000	0.01189	0.07277	1included	K562	AQR
MXE	POLB	ENSG00000070501.7	chr8	+	42214636	42214741	42214837	42214910	42213033	42213085	42218812	42218879	0.16400	0.00000	0.00000	1included	K562	AQR
MXE	POLB	ENSG00000070501.7	chr8	+	42218694	42218883	42226788	42226853	42214837	42214910	42227366	42227506	0.06000	0.00180	0.01516	1included	K562	AQR
MXE	POLB	ENSG00000070501.7	chr8	+	42218694	42218883	42226740	42226853	42214837	42214910	42227366	42227506	0.07000	0.00180	0.01518	1included	K562	AQR
MXE	POLB	ENSG00000070501.7	chr8	+	42226788	42226853	42227300	42227506	42218689	42218883	42229080	42229326	0.06700	0.00727	0.04893	1included	K562	AQR
MXE	POLB	ENSG00000070501.7	chr8	+	42226788	42226853	42227366	42227506	42218812	42218883	42229080	42229326	0.06400	0.00884	0.05730	1included	K562	AQR
MXE	POLB	ENSG00000070501.7	chr8	+	42218812	42218883	42226788	42226853	42213033	42213085	42227366	42227506	0.05400	0.01040	0.06536	1included	K562	AQR
MXE	POLB	ENSG00000070501.7	chr8	+	42218812	42218883	42227366	42227506	42202470	42202537	42229080	42229283	0.06800	0.00020	0.00222	1included	K562	AQR
MXE	POLB	ENSG00000070501.7	chr8	+	42218812	42218883	42227300	42227506	42202470	42202537	42229080	42229283	0.06900	0.00017	0.00196	1included	K562	AQR
MXE	POLB	ENSG00000070501.7	chr8	+	42218812	42218883	42226788	42226853	42202470	42202537	42227366	42227506	0.09000	0.00017	0.00193	1included	K562	AQR
MXE	POLB	ENSG00000070501.7	chr8	+	42218812	42218883	42227366	42227506	42196011	42196203	42229080	42229326	0.05100	0.00129	0.01137	1included	K562	AQR
MXE	POLB	ENSG00000070501.7	chr8	+	42218812	42218883	42226788	42226853	42214686	42214741	42227366	42227506	0.22400	0.00000	0.00000	1included	K562	AQR
MXE	POLB	ENSG00000070501.7	chr8	+	42218812	42218883	42227300	42227506	42195999	42196203	42229080	42229283	0.05100	0.00119	0.01064	1included	K562	AQR
MXE	POLB	ENSG00000070501.7	chr8	+	42213033	42213085	42226788	42226853	42202470	42202537	42227366	42227506	0.10000	0.00127	0.01124	1included	K562	AQR
MXE	POLB	ENSG00000070501.7	chr8	+	42213033	42213085	42214686	42214741	42202470	42202537	42214837	42214910	0.10900	0.00006	0.00077	1included	K562	AQR
MXE	POLB	ENSG00000070501.7	chr8	+	42218689	42218883	42226788	42226853	42213033	42213085	42227366	42227506	0.05400	0.00567	0.04000	1included	K562	AQR
MXE	POLB	ENSG00000070501.7	chr8	+	42214552	42214741	42214837	42214910	42213033	42213085	42218812	42218879	0.15500	0.00000	0.00000	1included	K562	AQR
MXE	POLB	ENSG00000070501.7	chr8	+	42207505	42207583	42210036	42210086	42206533	42206608	42211934	42212039	0.30800	0.01158	0.07130	1included	K562	AQR
MXE	POLB	ENSG00000070501.7	chr8	+	42207505	42207583	42210036	42210086	42206533	42206608	42213033	42213085	0.10500	0.00004	0.00049	1included	K562	AQR
MXE	POLB	ENSG00000070501.7	chr8	+	42214837	42214910	42218812	42218883	42214686	42214741	42226788	42226853	-0.26000	0.00000	0.00000	2included	K562	AQR
MXE	POLB	ENSG00000070501.7	chr8	+	42214686	42214741	42218689	42218883	42213033	42213085	42226788	42226853	-0.10400	0.00881	0.05713	2included	K562	AQR
MXE	POLB	ENSG00000070501.7	chr8	+	42214686	42214741	42218812	42218883	42213033	42213085	42226788	42226853	-0.11400	0.00898	0.05803	2included	K562	AQR
MXE	POLB	ENSG00000070501.7	chr8	+	42206533	42206608	42213033	42213125	42202470	42202537	42214686	42214741	-0.09500	0.00009	0.00107	2included	K562	AQR
MXE	POLB	ENSG00000070501.7	chr8	+	42206533	42206608	42213033	42213085	42202470	42202537	42227366	42227506	-0.10700	0.00027	0.00292	2included	K562	AQR
MXE	POLB	ENSG00000070501.7	chr8	+	42206533	42206608	42213033	42213085	42202470	42202537	42226788	42226853	-0.10900	0.00018	0.00200	2included	K562	AQR
MXE	POLB	ENSG00000070501.7	chr8	+	42220129	42220216	42226788	42226853	42218812	42218883	42229080	42229326	-0.09900	0.00015	0.00168	2included	K562	AQR
MXE	POLB	ENSG00000070501.7	chr8	+	42202470	42202537	42206533	42206608	42196529	42196587	42207524	42207583	-0.12000	0.00138	0.06538	2included	K562	UTP18
MXE	POLB	ENSG00000070501.7	chr8	+	42220129	42220216	42226788	42226853	42218812	42218883	42227366	42227506	0.15000	0.00732	0.08756	1included	K562	SF3B4
MXE	POLB	ENSG00000070501.7	chr8	+	42202470	42202537	42206533	42206608	42196529	42196587	42207524	42207583	-0.16300	0.00528	0.06798	2included	K562	SF3B4

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

POLB

General Information

Functions

Localization

Domains (AlphaFold: POLB)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for POLB is not avaliable on ENCORE database.

6 proteins are bound to POLB RNA:

eCLIP assay for POLB is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for POLB is not available on ENCORE database.

61 RBPs can affect the gene expression of POLB :

The Knockdown/knockout RNA-Seq assay for POLB is not available on ENCORE database.

20 RBPs can affect the splicing of POLB :

The Knockdown/knockout RNA-Seq assay for POLB is not avaliable on ENCORE database.