PLEKHA6

General Information

Gene Name       : PLEKHA6
Gene ID             : ENSG00000143850.14
Essential Gene : No

Functions

Localization

Domains (AlphaFold: PLEKHA6)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878PLEKHA6ENSG00000143850.140.040.030.04ENCSR000AEF
HepG2PLEKHA6ENSG00000143850.148.768.768.76ENCSR985KAT
K562PLEKHA6ENSG00000143850.140.000.010.01ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for PLEKHA6 is not avaliable on ENCORE database.



Proteins bound to RNA
  • PLEKHA6 RNA is bound by 15 proteins.  







eCLIP assay for PLEKHA6 is not avaliable on ENCORE database.





15 proteins are bound to PLEKHA6 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr1204191746204191866-3'-UTR,intron-Distal4.691535.14974HepG2UPF1
chr1204234012204234075-CDS,intron-Distal,intron-Proximal4.285358.17589HepG2PRPF8
chr1204197889204197964-CDS,intron-Distal3.761603.31827HepG2GRWD1
chr1204210502204210511-CDS,intron-Distal,intron-Proximal4.380853.37645HepG2PRPF8
chr1204242710204242799-CDS,intron-Distal,intron-Proximal3.861788.96944HepG2PRPF8
chr1204197775204197869-CDS,intron-Distal,intron-Proximal4.9115510.42975HepG2PRPF8
chr1204230586204230636-CDS,intron-Distal,intron-Proximal3.412705.58370HepG2PPIG
chr1204330931204330973-intron-Distal4.359443.44037HepG2DDX59
chr1204336938204336983-intron-Distal4.919605.56813HepG2PPIG
chr1204329052204329103-intron-Distal,intron-Proximal4.346453.23168HepG2DDX59
chr1204210450204210502-intron-Distal,intron-Proximal4.218904.45914HepG2PRPF8
chr1204329464204329517-intron-Distal3.571814.45183HepG2CSTF2T
chr1204335451204335537-intron-Distal5.4100617.52908HepG2PTBP1
chr1204340691204340734-intron-Distal4.195874.96634HepG2PPIG
chr1204231001204231055-intron-Distal4.715416.36553HepG2RBFOX2
chr1204336622204336694-intron-Distal3.817733.25786HepG2FAM120A
chr1204340655204340691-intron-Distal,intron-Proximal5.195875.56813HepG2PPIG
chr1204335451204335530-intron-Distal4.724214.66737HepG2MATR3
chr1204331260204331344-intron-Distal3.709663.67675HepG2DDX59
chr1204288877204289005-intron-Distal6.0139012.05379HepG2PCBP2
chr1204240450204240524-intron-Distal4.455414.64001HepG2U2AF2
chr1204334219204334310-intron-Distal3.828803.17235HepG2HNRNPK
chr1204306290204306350-intron-Distal3.905603.29248HepG2SUGP2
chr1204329420204329487-intron-Distal3.224483.70770HepG2DDX59
chr1204300756204300834-intron-Distal4.425554.40847HepG2PTBP1
chr1204300926204301022-intron-Distal3.424593.48223HepG2RBFOX2
chr1204331517204331611-intron-Distal3.247833.69530HepG2CSTF2T
chr1204324859204324927-intron-Distal4.272315.39633HepG2CSTF2
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for PLEKHA6 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for PLEKHA6 is not available on ENCORE database.

  • 89 RBPs can affect the levels of PLEKHA6.  








The Knockdown/knockout RNA-Seq assay for PLEKHA6 is not available on ENCORE database.





89 RBPs can affect the gene expression of PLEKHA6 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
PLEKHA6ENSG00000143850.8579.49710391.896100.564203.757602.84740HepG2ASCC1
PLEKHA6ENSG00000143850.8476.78100573.62300-0.266801.883201.32000HepG2CKAP4
PLEKHA6ENSG00000143850.8814.94370558.065800.546206.718705.80020HepG2CELF1
PLEKHA6ENSG00000143850.8582.18630354.187500.716907.749105.95350HepG2DDX1
PLEKHA6ENSG00000143850.8235.12940343.96290-0.548803.156402.17900HepG2DDX24
PLEKHA6ENSG00000143850.8224.62030339.00770-0.593803.432101.87410HepG2DDX28
PLEKHA6ENSG00000143850.8604.57480453.693000.414102.244101.67550HepG2DDX3X
PLEKHA6ENSG00000143850.8275.44040389.81770-0.501102.346401.77360HepG2DDX6
PLEKHA6ENSG00000143850.8444.97490548.96290-0.303001.976501.38900HepG2DKC1
PLEKHA6ENSG00000143850.8897.09360574.253000.643507.305805.51580HepG2EIF2S2
PLEKHA6ENSG00000143850.8576.77580413.997500.478302.606001.98430HepG2EIF4A3
PLEKHA6ENSG00000143850.8547.21580403.163500.440601.892501.31630HepG2EIF4B
PLEKHA6ENSG00000143850.8725.86340591.989700.294002.281701.50920HepG2EIF4G1
PLEKHA6ENSG00000143850.8762.34350567.083100.426803.072902.21650HepG2EIF4G2
PLEKHA6ENSG00000143850.8450.27180655.75940-0.542404.090702.78360HepG2ESF1
PLEKHA6ENSG00000143850.81063.88690764.398200.476803.246002.41840HepG2FIP1L1
PLEKHA6ENSG00000143850.8260.77430372.53850-0.514602.769301.49930HepG2FKBP4
PLEKHA6ENSG00000143850.8580.48690387.533800.582803.850003.07000HepG2G3BP1
PLEKHA6ENSG00000143850.8653.57730376.236600.796606.508604.92780HepG2GNB2L1
PLEKHA6ENSG00000143850.8259.16620407.98400-0.654602.735701.37690HepG2HLTF
PLEKHA6ENSG00000143850.8190.10810350.61840-0.883104.935204.10550HepG2HNRNPA1
PLEKHA6ENSG00000143850.8423.54930551.45580-0.380702.824401.88250HepG2HNRNPA2B1
PLEKHA6ENSG00000143850.8442.88310546.56650-0.303502.180301.57190HepG2HNRNPL
PLEKHA6ENSG00000143850.8527.67080387.434500.445603.866003.16020HepG2HNRNPU
PLEKHA6ENSG00000143850.8486.63990395.748800.298202.133801.48040HepG2ILF2
PLEKHA6ENSG00000143850.8622.46980417.977500.574503.904503.12610HepG2MAGOH
PLEKHA6ENSG00000143850.8869.60610420.296501.0489011.3618010.14610HepG2MATR3
PLEKHA6ENSG00000143850.81008.56260618.647300.705008.499307.15100HepG2MSI2
PLEKHA6ENSG00000143850.8481.56590624.96090-0.376002.126601.46780HepG2NSUN2
PLEKHA6ENSG00000143850.8445.45670259.515200.779403.889402.82420HepG2PABPC1
PLEKHA6ENSG00000143850.8622.37650374.081900.734309.214008.21120HepG2PCBP1
PLEKHA6ENSG00000143850.8260.10500402.39440-0.629503.101002.00530HepG2PCBP2
PLEKHA6ENSG00000143850.8462.23280345.557800.419602.692901.96450HepG2PPIL4
PLEKHA6ENSG00000143850.8551.79270380.619000.535704.397703.74270HepG2PTBP1
PLEKHA6ENSG00000143850.8717.31590388.193400.885705.266404.31080HepG2RAVER1
PLEKHA6ENSG00000143850.8229.33480381.55530-0.734403.344202.30400HepG2RPS10
PLEKHA6ENSG00000143850.8596.10120418.577800.510002.886001.78570HepG2RPS5
PLEKHA6ENSG00000143850.8482.72140345.018100.484404.208003.44230HepG2SAFB2
PLEKHA6ENSG00000143850.8491.23090349.013600.493002.834801.88480HepG2SERBP1
PLEKHA6ENSG00000143850.8498.12080710.70800-0.512803.181902.45760HepG2SF3A3
PLEKHA6ENSG00000143850.8612.47020300.649001.026503.332801.86220HepG2SNRNP200
PLEKHA6ENSG00000143850.81179.81060560.804801.0729028.3276026.61400HepG2SRSF5
PLEKHA6ENSG00000143850.8480.03900690.70230-0.524906.009805.30910HepG2SSB
PLEKHA6ENSG00000143850.8958.43780637.778600.587509.484608.45070HepG2SUCLG1
PLEKHA6ENSG00000143850.8539.50430371.757800.537204.622803.92700HepG2TAF15
PLEKHA6ENSG00000143850.8529.52200687.02620-0.375702.345901.67100HepG2TARDBP
PLEKHA6ENSG00000143850.8887.71500517.118700.779503.530302.33040HepG2TBRG4
PLEKHA6ENSG00000143850.8497.00660376.404500.400902.727302.22970HepG2TIAL1
PLEKHA6ENSG00000143850.8538.35850379.834300.503104.830804.12780HepG2TRIM56
PLEKHA6ENSG00000143850.8890.68620587.369100.600504.534703.44470HepG2UBE2L3
PLEKHA6ENSG00000143850.8791.14490630.290400.327803.101202.37120HepG2UPF1
PLEKHA6ENSG00000143850.8274.12940407.90860-0.573402.957701.91870HepG2UPF2
PLEKHA6ENSG00000143850.81036.45760693.197300.5802010.659309.76030HepG2ZNF622
PLEKHA6ENSG00000143850.852.649004.205903.645808.775506.63320K562ABCF1
PLEKHA6ENSG00000143850.825.450202.244503.503103.578501.61190K562ADAR
PLEKHA6ENSG00000143850.8212.754503.963305.7463046.3983044.25510K562AQR
PLEKHA6ENSG00000143850.843.481402.928303.892208.693306.18130K562BUD13
PLEKHA6ENSG00000143850.855.9571011.239802.315605.692203.53840K562CKAP4
PLEKHA6ENSG00000143850.853.227404.953003.425708.013406.15960K562CNOT7
PLEKHA6ENSG00000143850.862.1564010.180002.610103.429802.55390K562CPSF6
PLEKHA6ENSG00000143850.848.908305.451203.165306.286704.82830K562CELF1
PLEKHA6ENSG00000143850.824.621603.528002.802903.901703.14720K562DDX47
PLEKHA6ENSG00000143850.830.227902.010403.910205.549204.23160K562EFTUD2
PLEKHA6ENSG00000143850.826.008504.432202.552803.347002.31650K562EIF4G2
PLEKHA6ENSG00000143850.858.891303.210904.196909.395806.39780K562ESF1
PLEKHA6ENSG00000143850.845.644906.043002.917007.412505.29890K562EXOSC5
PLEKHA6ENSG00000143850.891.9015010.363403.148508.865707.29350K562FMR1
PLEKHA6ENSG00000143850.855.002208.786302.646107.016105.48980K562FTO
PLEKHA6ENSG00000143850.832.470206.219502.384204.293602.87880K562GLRX3
PLEKHA6ENSG00000143850.859.363409.717102.610907.146305.87000K562GPKOW
PLEKHA6ENSG00000143850.850.233808.238502.608104.514203.55180K562GRSF1
PLEKHA6ENSG00000143850.837.003504.636202.996504.933302.83620K562HNRNPAB
PLEKHA6ENSG00000143850.851.739402.542404.3469010.408409.31010K562HNRNPC
PLEKHA6ENSG00000143850.820.631403.187802.694103.297802.13310K562HNRNPL
PLEKHA6ENSG00000143850.856.411508.303202.764206.668605.14970K562KRR1
PLEKHA6ENSG00000143850.848.422109.486002.351705.247004.01690K562METAP2
PLEKHA6ENSG00000143850.834.557706.538602.401904.387203.38950K562MTPAP
PLEKHA6ENSG00000143850.858.485707.267303.008505.256404.27520K562NSUN2
PLEKHA6ENSG00000143850.843.481304.758403.191805.554503.79180K562PABPC1
PLEKHA6ENSG00000143850.821.393701.956503.450703.263702.44830K562PRPF8
PLEKHA6ENSG00000143850.897.019704.835704.3264015.5644013.60470K562PUF60
PLEKHA6ENSG00000143850.826.747105.144902.378102.989401.87550K562PUM1
PLEKHA6ENSG00000143850.829.966805.039602.571903.699902.58720K562PUM2
PLEKHA6ENSG00000143850.829.511003.472103.087304.582003.90610K562PUS1
PLEKHA6ENSG00000143850.832.220004.512102.836004.398002.38620K562SBDS
PLEKHA6ENSG00000143850.830.778707.167402.102303.310902.42230K562SF3A3
PLEKHA6ENSG00000143850.853.195509.249602.523702.680301.72110K562SF3B1
PLEKHA6ENSG00000143850.818.515602.418602.936403.244601.86430K562SLBP
PLEKHA6ENSG00000143850.848.371503.628303.736708.794806.49920K562STAU1
PLEKHA6ENSG00000143850.830.802404.416202.802103.935001.97270K562STIP1
PLEKHA6ENSG00000143850.824.479401.885503.698503.757002.55740K562SUPV3L1
PLEKHA6ENSG00000143850.827.966403.540302.981704.348802.49710K562TRIP6
PLEKHA6ENSG00000143850.817.301502.000003.112702.566901.59140K562UCHL5
PLEKHA6ENSG00000143850.833.200807.705502.107203.537902.73290K562UPF1
PLEKHA6ENSG00000143850.823.225004.594902.337502.950001.70450K562UTP3
PLEKHA6ENSG00000143850.833.011106.593702.323704.194003.10860K562WDR3
PLEKHA6ENSG00000143850.818.977602.043603.215003.041701.75370K562XRN2
PLEKHA6ENSG00000143850.831.575304.461102.823205.237803.98820K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for PLEKHA6 is not available on ENCORE database.





2 RBPs can affect the splicing of PLEKHA6 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEPLEKHA6ENSG00000143850.8chr1-2042259292042260162042196732042197422042264802042269970.508000.000250.00431includedHepG2U2AF2
SEPLEKHA6ENSG00000143850.8chr1-2042139912042141312042108122042109422042147422042148540.133000.010980.09822includedHepG2U2AF2
SEPLEKHA6ENSG00000143850.8chr1-204212241204212391204210812204210942204213991204214131-0.060000.000610.00930excludedHepG2U2AF2
SEPLEKHA6ENSG00000143850.8chr1-2042139912042141312042108122042109422042147422042148540.198000.000490.02698includedHepG2SFPQ
SEPLEKHA6ENSG00000143850.8chr1-204212241204212391204210812204210942204213991204214131-0.054000.001840.07100excludedHepG2SFPQ

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for PLEKHA6 is not avaliable on ENCORE database.