PDS5B

General Information

Gene Name       : PDS5B
Gene ID             : ENSG00000083642.18
Essential Gene : No

Functions

Localization

Domains (AlphaFold: PDS5B)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878PDS5BENSG00000083642.1836.2833.1434.71ENCSR000AEF
HepG2PDS5BENSG00000083642.1810.6520.1915.42ENCSR985KAT
K562PDS5BENSG00000083642.189.0912.9311.01ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for PDS5B is not avaliable on ENCORE database.



Proteins bound to RNA
  • PDS5B RNA is bound by 26 proteins.  







eCLIP assay for PDS5B is not avaliable on ENCORE database.





26 proteins are bound to PDS5B RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr133334924433349343+3'-UTR3.228284.76050HepG2GRWD1
chr133334924633349366+3'-UTR3.330906.45823K562ZNF622
chr133334947333349537+3'-UTR4.708807.89476HepG2FUBP3
chr133334947233349548+3'-UTR5.5033429.37775K562PUM2
chr133334924333349306+3'-UTR3.735556.06436HepG2BCLAF1
chr133334968033349758+3'-UTR4.9364711.82794K562PUM2
chr133334962333349683+3'-UTR5.004726.77531HepG2FUBP3
chr133334948033349548+3'-UTR4.712074.73315K562TIA1
chr133334924833349324+3'-UTR3.996113.45225K562GRWD1
chr133316064933160736+5'-UTR,intron-Proximal4.4977612.21923K562UCHL5
chr133316070833160741+5'-UTR,intron-Proximal4.096493.72434HepG2NCBP2
chr133316064333160732+5'-UTR,intron-Proximal4.3374510.09214K562DDX24
chr133316064833160728+5'-UTR4.8147211.80957HepG2BCLAF1
chr133316059933160718+5'-UTR4.505103.91454K562PUM1
chr133316064733160731+5'-UTR,intron-Proximal3.168497.44115K562ZNF622
chr133316064333160730+5'-UTR3.9141212.94827HepG2PPIG
chr133316064433160708+5'-UTR5.2658910.57527HepG2NCBP2
chr133322594033226009+CDS,intron-Proximal4.7150710.64218HepG2BCLAF1
chr133325000133250061+CDS4.041143.43980K562ZNF622
chr133323257033232628+CDS,intron-Proximal3.845606.97808HepG2BCLAF1
chr133334442033344555+CDS5.392299.91399K562UCHL5
chr133331676633316861+CDS5.533788.86847HepG2BCLAF1
chr133326264633262714+CDS,intron-Proximal3.676665.15500HepG2BCLAF1
chr133334739533347456+CDS,intron-Distal3.831783.01428K562UCHL5
chr133322593733226009+CDS,intron-Proximal4.042723.44423K562BUD13
chr133334463733344697+CDS4.496855.14565K562UCHL5
chr133326131433261368+CDS4.754075.70640HepG2BCLAF1
chr133322609633226139+CDS5.136096.71715HepG2BCLAF1
chr133323245333232462+CDS4.720394.70478HepG2BCLAF1
chr133334433233344445+CDS4.457144.13543HepG2FXR2
chr133326262433262713+CDS,intron-Proximal3.960613.34184HepG2GRWD1
chr133323334433233419+CDS,intron-Proximal3.599416.20035HepG2BCLAF1
chr133326259833262646+CDS3.337624.56058HepG2BCLAF1
chr133334448933344509+CDS4.136093.06595HepG2BCLAF1
chr133324744633247493+CDS3.980334.51739HepG2BCLAF1
chr133322601433226089+CDS3.437466.60490HepG2BCLAF1
chr133323262833232669+CDS,intron-Proximal5.319368.07539HepG2BCLAF1
chr133323329033233334+CDS,intron-Proximal5.200227.05570HepG2BCLAF1
chr133324997933250026+CDS,intron-Proximal3.517574.85828HepG2BCLAF1
chr133322599733226025+CDS4.000333.65750K562YBX3
chr133330626433306349+CDS3.817306.81385HepG2BCLAF1
chr133327395633274009+CDS,intron-Proximal3.732414.52024HepG2PPIG
chr133328107833281162+CDS3.173845.00751HepG2BCLAF1
chr133334432733344395+CDS3.469145.15500HepG2BCLAF1
chr133324735133247409+CDS,intron-Proximal4.695694.90235K562SF3B4
chr133334441833344474+CDS3.920633.20027K562ZNF622
chr133325812433258161+CDS,intron-Proximal3.241304.74886HepG2BCLAF1
chr133325297133253062+CDS,intron-Proximal4.4127212.88094HepG2BCLAF1
chr133326126933261305+CDS,intron-Proximal5.093117.39496HepG2BCLAF1
chr133324190033241978+CDS,intron-Proximal4.263859.37631HepG2BCLAF1
chr133325006633250096+CDS3.952035.36555HepG2BCLAF1
chr133327552533275578+CDS,intron-Proximal3.448824.85828HepG2BCLAF1
chr133323239933232439+CDS4.530344.34038HepG2BCLAF1
chr133332015633320196+CDS3.239354.29172K562YBX3
chr133334458533344643+CDS3.757893.43526K562GRWD1
chr133327545933275525+CDS,intron-Proximal3.084456.33024HepG2BCLAF1
chr133316926133169362+intron-Distal4.636345.20135HepG2QKI
chr133327493133275007+intron-Distal4.165108.11145K562KHSRP
chr133318565533185704+intron-Distal3.384073.84025HepG2SUGP2
chr133326849833268591+intron-Distal,intron-Proximal4.197404.07352K562KHSRP
chr133316094533161012+intron-Distal4.802135.19274K562XRN2
chr133323074733230791+intron-Distal4.058159.39331K562EXOSC5
chr133327481933274931+intron-Distal3.115345.82594K562KHSRP
chr133318925233189427+intron-Distal4.353694.54401K562KHSRP
chr133316093533161005+intron-Distal4.198965.55608HepG2XRN2
chr133319611433196204+intron-Distal4.422344.07628HepG2PTBP1
chr133318790533187978+intron-Distal3.047214.24752K562KHSRP
chr133325404233254148+intron-Distal4.582344.30178K562PTBP1
chr133326973233269801+intron-Distal3.775063.24603K562KHSRP
chr133318782733187860+intron-Distal4.863006.07567K562KHSRP
chr133320811533208228+intron-Distal4.024605.39628K562PTBP1
chr133316123133161287+intron-Distal4.980684.92816HepG2XRN2
chr133317970333179811+intron-Distal4.025973.86809HepG2SUGP2
chr133323156233231606+intron-Distal4.235283.30687K562EXOSC5
chr133317971833179802+intron-Distal4.389794.80466K562EXOSC5
chr133316159433161672+intron-Distal4.012783.02234K562KHSRP
chr133319873333198812+intron-Distal4.052383.34098HepG2HNRNPM
chr133316109833161159+intron-Distal5.591105.22378HepG2XRN2
chr133317769233177760+intron-Distal4.007023.01445K562EXOSC5
chr133321972633219830+intron-Distal3.128873.73266K562KHSRP
chr133317970533179783+intron-Distal3.931733.24322HepG2MATR3
chr133322983733229879+intron-Distal4.214543.89080K562EXOSC5
chr133327148833271558+intron-Distal3.077973.46866HepG2U2AF2
chr133319624933196340+intron-Distal3.858405.07626HepG2PTBP1
chr133318775033187827+intron-Distal5.085397.17304K562KHSRP
chr133316079633160875+intron-Distal,intron-Proximal4.314889.40513HepG2NKRF
chr133316095833161021+intron-Distal3.865027.01311HepG2NKRF
chr133319615533196202+intron-Distal4.663295.04993HepG2QKI
chr133316300633163064+intron-Distal3.548424.57394K562HNRNPM
chr133330263733302793+intron-Distal4.283254.53347HepG2SUGP2
chr133328004933280105+intron-Distal5.013736.79267HepG2ILF3
chr133316111533161189+intron-Distal3.720544.03838HepG2NKRF
chr133331248033312627+intron-Distal3.966223.71397K562KHSRP
chr133327531633275400+intron-Distal,intron-Proximal4.401584.31512K562KHSRP
chr133317841433178478+intron-Distal5.338509.02315K562EXOSC5
chr133318803333188122+intron-Distal3.039015.34873K562KHSRP
chr133316300833163073+intron-Distal3.832634.87260HepG2HNRNPM
chr133316122433161298+intron-Distal4.113488.45007HepG2NKRF
chr133322953033229576+intron-Distal3.118213.15041K562EXOSC5
chr133316281633162948+intron-Distal3.881263.02234K562KHSRP
chr133323102133231075+intron-Distal3.812745.50914K562EXOSC5
chr133324721233247284+intron-Distal,intron-Proximal3.299513.28806K562KHSRP
chr133323024133230269+intron-Distal3.957253.01456K562EXOSC5
chr133331383333313973+intron-Distal4.090074.76003K562KHSRP
chr133316138033161425+intron-Distal3.319946.37066HepG2NKRF
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for PDS5B is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for PDS5B is not available on ENCORE database.

  • 88 RBPs can affect the levels of PDS5B.  








The Knockdown/knockout RNA-Seq assay for PDS5B is not available on ENCORE database.





88 RBPs can affect the gene expression of PDS5B :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
PDS5BENSG00000083642.14990.501901434.80430-0.534609.110607.98480HepG2AUH
PDS5BENSG00000083642.14510.48490903.84580-0.824204.811303.57340HepG2BCCIP
PDS5BENSG00000083642.14446.79930785.48110-0.813905.345604.13510HepG2BCLAF1
PDS5BENSG00000083642.141004.475501842.88020-0.8755014.7432013.51420HepG2BOP1
PDS5BENSG00000083642.14601.786101002.49770-0.7363015.2058013.90780HepG2CKAP4
PDS5BENSG00000083642.14946.214301691.87460-0.8384012.2934010.96010HepG2CPSF6
PDS5BENSG00000083642.14716.941401157.71270-0.6914012.3641011.19420HepG2CELF1
PDS5BENSG00000083642.14966.782201244.98560-0.364904.660403.73600HepG2DAZAP1
PDS5BENSG00000083642.14722.58890927.34120-0.359904.043403.05870HepG2DDX19B
PDS5BENSG00000083642.14532.13640831.59110-0.644103.116101.75310HepG2DDX27
PDS5BENSG00000083642.14724.43150992.92130-0.454803.129602.46890HepG2DDX3X
PDS5BENSG00000083642.14571.35210888.61100-0.637203.667802.79100HepG2DDX55
PDS5BENSG00000083642.141029.825201320.09530-0.358202.698701.69810HepG2DDX5
PDS5BENSG00000083642.14556.79620852.77800-0.615004.574203.79660HepG2DDX6
PDS5BENSG00000083642.14593.75650783.15930-0.399402.928901.92480HepG2DHX30
PDS5BENSG00000083642.14509.69430811.98050-0.671809.111807.88960HepG2DNAJC21
PDS5BENSG00000083642.14528.85530804.83060-0.605809.711808.57830HepG2DNAJC2
PDS5BENSG00000083642.14439.80260819.95690-0.898709.382108.32880HepG2EIF2S1
PDS5BENSG00000083642.14833.347001176.48200-0.497504.730403.68370HepG2EIF4G2
PDS5BENSG00000083642.141256.053601647.33960-0.391205.443404.64830HepG2ETF1
PDS5BENSG00000083642.14797.47210979.82710-0.297102.076601.35450HepG2EWSR1
PDS5BENSG00000083642.14724.38930510.591900.504503.034502.21390HepG2FUBP3
PDS5BENSG00000083642.14672.64950908.12020-0.433002.501801.53960HepG2GNB2L1
PDS5BENSG00000083642.141132.746001917.89950-0.759708.850507.74920HepG2GPKOW
PDS5BENSG00000083642.14741.70110957.28610-0.368104.077402.90580HepG2HDGF
PDS5BENSG00000083642.14629.29230819.75970-0.381502.483201.86850HepG2HNRNPA1
PDS5BENSG00000083642.14910.255801144.10010-0.329903.673502.62110HepG2HNRNPA2B1
PDS5BENSG00000083642.14815.416201167.96980-0.518407.661106.54720HepG2HNRNPF
PDS5BENSG00000083642.14803.816801134.13520-0.496708.802407.66550HepG2HNRNPL
PDS5BENSG00000083642.141122.445801830.28430-0.705408.719807.66910HepG2HNRNPLL
PDS5BENSG00000083642.14662.48030905.80880-0.451305.714904.86840HepG2HNRNPU
PDS5BENSG00000083642.14772.990201150.12050-0.573307.220606.10020HepG2IGF2BP1
PDS5BENSG00000083642.14656.73480862.11320-0.392602.470801.82870HepG2IGF2BP2
PDS5BENSG00000083642.14629.68590925.25250-0.555209.416508.14400HepG2ILF2
PDS5BENSG00000083642.141523.611002161.73600-0.504703.339502.42590HepG2LARP4
PDS5BENSG00000083642.14575.14990934.23420-0.699806.596704.77050HepG2LIN28B
PDS5BENSG00000083642.141243.626801622.87690-0.384003.262902.45130HepG2NSUN2
PDS5BENSG00000083642.141020.48840858.536300.249202.051801.56820HepG2PTBP1
PDS5BENSG00000083642.14615.617301178.40960-0.9367015.6191014.35640HepG2PUF60
PDS5BENSG00000083642.14876.581601021.28000-0.220401.925401.39200HepG2PUS1
PDS5BENSG00000083642.141137.58820929.851100.290802.318001.73680HepG2QKI
PDS5BENSG00000083642.141296.520701550.20260-0.257802.087001.32870HepG2RBM15
PDS5BENSG00000083642.14727.293901072.55830-0.560404.411603.13960HepG2RBM27
PDS5BENSG00000083642.141430.34290955.482200.582009.779108.87610HepG2NELFE
PDS5BENSG00000083642.141075.12950889.877000.272702.402201.82270HepG2RECQL
PDS5BENSG00000083642.14755.086401258.13610-0.736609.790708.63760HepG2RPLP0
PDS5BENSG00000083642.14685.18220989.24150-0.529804.092803.12820HepG2RPS2
PDS5BENSG00000083642.14376.74230678.43010-0.848605.546004.46820HepG2RRP9
PDS5BENSG00000083642.14640.63150806.65880-0.332503.207002.52370HepG2SAFB2
PDS5BENSG00000083642.141979.271901372.049400.528503.451302.69550HepG2SF3A3
PDS5BENSG00000083642.141236.943201811.63600-0.550506.379105.34480HepG2SF3B1
PDS5BENSG00000083642.14912.925801129.80420-0.307503.810403.00740HepG2SLBP
PDS5BENSG00000083642.141348.911402015.75700-0.579503.697002.78870HepG2SNRNP70
PDS5BENSG00000083642.141182.222901555.12990-0.395506.045105.38360HepG2SRFBP1
PDS5BENSG00000083642.141409.57230933.001600.5952010.704509.90670HepG2SRSF1
PDS5BENSG00000083642.14671.704601147.47940-0.7726015.1828013.77710HepG2SRSF7
PDS5BENSG00000083642.14641.25330759.03620-0.243301.912201.43760HepG2SRSF9
PDS5BENSG00000083642.14730.18410949.70110-0.379202.352701.48030HepG2SUPT6H
PDS5BENSG00000083642.14545.28700884.68840-0.698203.985803.19630HepG2SUPV3L1
PDS5BENSG00000083642.141054.69840838.584800.330702.958802.38130HepG2TAF15
PDS5BENSG00000083642.14868.779001783.88660-1.0380018.9400017.35630HepG2TARDBP
PDS5BENSG00000083642.14395.25840593.03040-0.585302.907601.88840HepG2TFIP11
PDS5BENSG00000083642.14428.95990880.13740-1.0369017.8252016.75960HepG2TIAL1
PDS5BENSG00000083642.14609.02760888.03210-0.544107.705606.84180HepG2TRIM56
PDS5BENSG00000083642.14339.55830522.67410-0.622303.476702.62990HepG2UCHL5
PDS5BENSG00000083642.14971.587601216.79720-0.324703.872403.06660HepG2UPF1
PDS5BENSG00000083642.141013.723301250.70380-0.303103.163602.05190HepG2UTP18
PDS5BENSG00000083642.14751.783101174.77120-0.6440011.7865010.68550HepG2UTP3
PDS5BENSG00000083642.14584.22140870.87600-0.576002.868202.13010HepG2XRN2
PDS5BENSG00000083642.14902.150901338.24520-0.5689012.2971011.35050HepG2ZNF622
PDS5BENSG00000083642.141215.229101477.91480-0.282302.875601.74440K562CPEB4
PDS5BENSG00000083642.14519.41470722.57660-0.476302.340801.38540K562DDX3X
PDS5BENSG00000083642.14833.250601242.86120-0.576804.848903.70350K562FIP1L1
PDS5BENSG00000083642.141196.16680801.019800.578403.682002.84060K562G3BP2
PDS5BENSG00000083642.14851.573801063.09510-0.320102.263401.54450K562GPKOW
PDS5BENSG00000083642.14796.527401232.87080-0.630207.746906.46920K562GRSF1
PDS5BENSG00000083642.141159.915701685.16340-0.538904.249203.26860K562HSPD1
PDS5BENSG00000083642.141497.939401114.258000.426802.621801.82100K562KIF1C
PDS5BENSG00000083642.14752.76270928.00310-0.301902.203301.38880K562MATR3
PDS5BENSG00000083642.141567.265201248.247300.328202.618501.73820K562MBNL1
PDS5BENSG00000083642.14815.736101037.70300-0.347202.688501.82810K562METAP2
PDS5BENSG00000083642.141297.54420874.929000.568402.408301.59870K562NAA15
PDS5BENSG00000083642.141299.25380957.062200.440903.252102.34950K562PCBP3
PDS5BENSG00000083642.141007.50480734.097500.456604.485503.46360K562POLR2G
PDS5BENSG00000083642.14862.407901410.78280-0.710104.919103.77590K562PPIG
PDS5BENSG00000083642.141542.810101041.285200.567105.582404.84310K562PUS1
PDS5BENSG00000083642.141402.099701014.538600.466705.985505.13980K562RBM15
PDS5BENSG00000083642.14633.62270870.92340-0.458903.819102.55300K562SRSF4
PDS5BENSG00000083642.14895.40550736.321500.282102.047201.33980K562SYNCRIP
PDS5BENSG00000083642.14683.55960896.35290-0.391002.751702.04580K562TARDBP
PDS5BENSG00000083642.14666.69910864.62580-0.375002.979102.12560K562TIA1
PDS5BENSG00000083642.14983.62630801.660000.295002.230201.50960K562U2AF2
PDS5BENSG00000083642.141238.145901049.823900.237902.390601.59970K562WDR43
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for PDS5B is not available on ENCORE database.





7 RBPs can affect the splicing of PDS5B :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEPDS5BENSG00000083642.14chr13+333337653333382833332671333327913333471233334858-0.141000.000010.00025excludedHepG2U2AF1
SEPDS5BENSG00000083642.14chr13+333337653333382833332671333327913333471233334858-0.185000.000050.00115excludedHepG2U2AF2
SEPDS5BENSG00000083642.14chr13+333447913334489933344258333446983334732633347462-0.067000.002660.03183excludedHepG2U2AF2
SEPDS5BENSG00000083642.14chr13+3324874633248882332473323324749333249980332500960.111000.000370.00520includedK562AQR
SEPDS5BENSG00000083642.14chr13+333447913334489933344258333446983334732633347462-0.145000.010120.08202excludedK562AQR
SEPDS5BENSG00000083642.14chr13+333447913334489933344258333446983334732633347462-0.289000.000840.04510excludedK562EFTUD2
SEPDS5BENSG00000083642.14chr13+333447913334489933344258333446983334732633347462-0.184000.000000.00000excludedHepG2SF3A3
SEPDS5BENSG00000083642.14chr13+333447913334489933344258333446983334732633347462-0.135000.003500.07128excludedK562AGGF1
SEPDS5BENSG00000083642.14chr13+333447913334489933344258333446983334732633347462-0.234000.002520.08588excludedHepG2HNRNPU
A3SSPDS5BENSG00000083642.14chr13+3327095333271039332709903327103933268359332684410.124000.006850.03805longerK562AQR
A3SSPDS5BENSG00000083642.14chr13+3333469033334858333347123333485833333765333338280.119000.001620.01067longerK562AQR
A3SSPDS5BENSG00000083642.14chr13+3328102233281176332810703328117633275459332755750.130000.000930.00654longerK562AQR
MXEPDS5BENSG00000083642.14chr13+33316697333168653332011433320238333152173331528633327469333276740.092000.011000.068351includedK562AQR
MXEPDS5BENSG00000083642.14chr13+33281022332811763328408233284243332754593327557533306237333063610.184000.000480.004811includedK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for PDS5B is not avaliable on ENCORE database.