PARP12

General Information

Gene Name       : PARP12
Gene ID             : ENSG00000059378.12
Essential Gene : No

Functions

Localization

Domains (AlphaFold: PARP12)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878PARP12ENSG00000059378.1212.4213.2712.84ENCSR000AEF
HepG2PARP12ENSG00000059378.128.939.018.97ENCSR985KAT
K562PARP12ENSG00000059378.1217.8118.6118.21ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  
  GeneName    Cell_Line    Method    Exp_ID    Control_ID    Sample_reps    Control_reps    KD%    Status    Project    Note  
PARP12Ribo-STAMP-293TshRNABGRSLV10-19,BGRSLV10-20BGRSLV10-1,BGRSLV10-2NotSatisfiedENCORE2


  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for PARP12 is not avaliable on ENCORE database.



Proteins bound to RNA
  • PARP12 RNA is bound by 10 proteins.  







eCLIP assay for PARP12 is not avaliable on ENCORE database.





10 proteins are bound to PARP12 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr7139724629139724715-3'-UTR,CDS,intron-Distal3.860594.00320K562AQR
chr7139725919139726003-3'-UTR,CDS,intron-Distal,intron-Proximal5.622379.23760K562AQR
chr7139728362139728477-3'-UTR,CDS,intron-Distal,intron-Proximal4.9889513.44390HepG2PRPF8
chr7139754545139754614-CDS,intron-Distal,intron-Proximal4.089945.16342K562SF3B4
chr7139730373139730476-intron-Distal3.085443.20028K562TARDBP
chr7139740079139740191-intron-Distal4.659983.96879HepG2MATR3
chr7139728769139728838-intron-Distal3.514575.38829K562KHSRP
chr7139735621139735761-intron-Distal4.8823813.25687HepG2PCBP2
chr7139734144139734223-intron-Distal,intron-Proximal3.433435.14864K562KHSRP
chr7139752612139752822-intron-Distal3.051784.61304K562KHSRP
chr7139735590139735694-intron-Distal3.245824.22071K562ILF3
chr7139739597139739663-intron-Distal3.261064.61989HepG2SUGP2
chr7139738715139738778-intron-Distal4.477534.78128HepG2SUGP2
chr7139739399139739485-intron-Distal3.843516.51675HepG2SUGP2
chr7139728495139728605-intron-Distal,intron-Proximal4.514576.28383K562KHSRP
chr7139729631139729756-intron-Distal3.091274.89694K562MATR3
chr7139738985139739048-intron-Distal3.870513.47525K562MATR3
chr7139732393139732448-intron-Distal3.242493.93901K562KHSRP
chr7139739846139739904-intron-Distal4.516544.78128HepG2SUGP2
chr7139735625139735739-intron-Distal4.705338.54663K562PTBP1
chr7139753585139753674-intron-Distal3.607853.06150K562KHSRP
chr7139728838139728912-intron-Distal3.562555.83959K562KHSRP
chr7139740308139740364-intron-Distal4.375465.04879HepG2SUGP2
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for PARP12 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for PARP12 is not available on ENCORE database.

  • 85 RBPs can affect the levels of PARP12.  








The Knockdown/knockout RNA-Seq assay for PARP12 is not available on ENCORE database.





85 RBPs can affect the gene expression of PARP12 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
PARP12ENSG00000059378.8340.23090593.29050-0.802206.131804.79060HepG2ABCF1
PARP12ENSG00000059378.8363.64490502.98590-0.468004.141003.42550HepG2ACO1
PARP12ENSG00000059378.8347.61850604.26640-0.797705.849705.10940HepG2AKAP1
PARP12ENSG00000059378.8635.04660505.350700.329502.559201.81830HepG2AKAP8L
PARP12ENSG00000059378.8349.25300240.580300.537702.359801.53200HepG2BCLAF1
PARP12ENSG00000059378.8395.13420502.87860-0.347902.578301.93190HepG2CKAP4
PARP12ENSG00000059378.8635.81520454.588600.483904.158703.40100HepG2CELF1
PARP12ENSG00000059378.8639.89880488.856200.388303.369402.56600HepG2DAZAP1
PARP12ENSG00000059378.8363.67190465.19080-0.355202.645701.82830HepG2DDX19B
PARP12ENSG00000059378.8144.50150318.70870-1.141209.702008.51330HepG2DDX21
PARP12ENSG00000059378.8959.80660578.810600.729606.898205.95290HepG2DDX3X
PARP12ENSG00000059378.8403.02850272.234400.565902.611001.85720HepG2DDX55
PARP12ENSG00000059378.8338.93790497.28300-0.553003.021002.37830HepG2DDX6
PARP12ENSG00000059378.8519.83060277.671600.904609.391307.70080HepG2DHX30
PARP12ENSG00000059378.8257.68020481.22180-0.9011010.419409.27580HepG2DKC1
PARP12ENSG00000059378.8468.71580287.893200.703106.901805.83130HepG2DNAJC21
PARP12ENSG00000059378.8635.83060477.978000.411602.322701.77580HepG2EIF2S1
PARP12ENSG00000059378.8367.03280528.18700-0.525102.938002.27840HepG2EIF4A3
PARP12ENSG00000059378.8263.00280514.33080-0.967606.675705.63930HepG2EIF4B
PARP12ENSG00000059378.8749.49400482.233400.636108.008306.72150HepG2EIF4G1
PARP12ENSG00000059378.8640.47440461.958300.471303.099102.23960HepG2EIF4G2
PARP12ENSG00000059378.8386.85760513.79180-0.409402.573801.51920HepG2ESF1
PARP12ENSG00000059378.8572.22260744.77470-0.380203.417402.75930HepG2ETF1
PARP12ENSG00000059378.8433.00060599.03300-0.468302.632001.88000HepG2FIP1L1
PARP12ENSG00000059378.8503.03040368.794800.447702.700201.92310HepG2FUBP3
PARP12ENSG00000059378.8101.66660290.65120-1.5154012.9074011.68110HepG2HNRNPA1
PARP12ENSG00000059378.8211.44020323.29410-0.612603.244102.49950HepG2HNRNPC
PARP12ENSG00000059378.8572.56840403.636100.504304.822503.90970HepG2HNRNPF
PARP12ENSG00000059378.8316.24690500.75710-0.663104.746403.85280HepG2HNRNPK
PARP12ENSG00000059378.8425.21300316.695500.425002.020801.47420HepG2HNRNPLL
PARP12ENSG00000059378.8581.30100397.467000.548404.696603.77610HepG2IGF2BP1
PARP12ENSG00000059378.8527.07680730.99160-0.471802.526701.34410HepG2KRR1
PARP12ENSG00000059378.8344.04630533.21080-0.632104.292803.47910HepG2MAGOH
PARP12ENSG00000059378.8336.58570536.17790-0.671704.342803.56940HepG2MATR3
PARP12ENSG00000059378.8236.99640317.89230-0.423702.346101.55920HepG2PARN
PARP12ENSG00000059378.8318.84830549.30820-0.784709.655108.63170HepG2PCBP1
PARP12ENSG00000059378.8340.90300452.06160-0.407202.284501.57360HepG2PRPF4
PARP12ENSG00000059378.8322.29240209.987700.618003.000702.16180HepG2PRPF8
PARP12ENSG00000059378.8368.56880558.94160-0.600805.689704.96180HepG2PTBP1
PARP12ENSG00000059378.8332.31100462.71480-0.477603.135202.50690HepG2PUF60
PARP12ENSG00000059378.8352.17910490.82580-0.478903.499802.74950HepG2PUM2
PARP12ENSG00000059378.8410.96150512.32410-0.318102.252001.68310HepG2PUS1
PARP12ENSG00000059378.8422.76120549.39190-0.378002.337801.71240HepG2RBM25
PARP12ENSG00000059378.8237.24790622.04840-1.3906024.5920023.29900HepG2NELFE
PARP12ENSG00000059378.8312.12360579.35350-0.8923011.7204010.58530HepG2RECQL
PARP12ENSG00000059378.8426.42720286.005300.576205.072804.24820HepG2SAFB2
PARP12ENSG00000059378.8376.97500268.231200.490902.455001.56750HepG2SERBP1
PARP12ENSG00000059378.8325.24900593.70120-0.868206.704405.62420HepG2SF3A3
PARP12ENSG00000059378.8454.72070581.93040-0.355902.542901.97210HepG2SF3B4
PARP12ENSG00000059378.8434.55040607.40940-0.483104.285103.72820HepG2SRSF1
PARP12ENSG00000059378.8527.12130396.557100.410503.333002.57880HepG2SRSF7
PARP12ENSG00000059378.8372.36490494.15990-0.408303.199702.61540HepG2SRSF9
PARP12ENSG00000059378.8121.43040610.40830-2.3296058.8955057.29220HepG2SSB
PARP12ENSG00000059378.8537.03550728.97240-0.440802.665801.40640HepG2SSRP1
PARP12ENSG00000059378.8451.29500270.999600.735704.247303.43450HepG2SUPV3L1
PARP12ENSG00000059378.8382.66000545.96320-0.512704.196103.52730HepG2TAF15
PARP12ENSG00000059378.8346.96850512.31340-0.562204.050403.29590HepG2U2AF1
PARP12ENSG00000059378.8821.83950526.523400.642309.704008.53210HepG2UPF1
PARP12ENSG00000059378.8634.74850383.876100.725404.955903.47440HepG2XPO5
PARP12ENSG00000059378.8171.61900266.76960-0.636402.859702.12320HepG2XRN2
PARP12ENSG00000059378.8322.59300446.13610-0.467803.746802.98510HepG2ZC3H8
PARP12ENSG00000059378.81369.36920988.130400.470603.250702.54090K562AKAP8L
PARP12ENSG00000059378.8919.65480507.983600.856209.774008.08500K562BOP1
PARP12ENSG00000059378.8931.21610694.571500.422902.793101.36890K562BUD13
PARP12ENSG00000059378.81663.00630954.692500.800605.701804.11940K562CNOT7
PARP12ENSG00000059378.8846.06710540.095000.647507.189505.91710K562CPSF6
PARP12ENSG00000059378.82657.961401698.162500.6462011.611409.69150K562CELF1
PARP12ENSG00000059378.81488.395501066.815200.480306.523704.63040K562DDX21
PARP12ENSG00000059378.81544.498401113.619900.471807.760406.74510K562DDX47
PARP12ENSG00000059378.8902.16830495.402300.864702.247201.35220K562EIF3A
PARP12ENSG00000059378.8703.08350518.009600.440604.137503.17390K562EIF3G
PARP12ENSG00000059378.81765.178401380.941900.354104.285903.12460K562EIF4G2
PARP12ENSG00000059378.81164.00610892.981300.382303.494002.04870K562EXOSC5
PARP12ENSG00000059378.8950.97710716.804600.407702.861101.99730K562FIP1L1
PARP12ENSG00000059378.8713.29980549.606000.376002.335201.54790K562FMR1
PARP12ENSG00000059378.8609.59830465.871900.387802.155801.35380K562FTO
PARP12ENSG00000059378.8772.29660603.092000.356703.131302.49350K562FXR1
PARP12ENSG00000059378.81077.58300805.424700.419904.652403.18060K562GLRX3
PARP12ENSG00000059378.8822.91150515.628100.674306.962905.70030K562GPKOW
PARP12ENSG00000059378.81391.361601120.617800.312102.309901.61550K562GRSF1
PARP12ENSG00000059378.8359.26510615.40590-0.776506.779904.76910K562HNRNPK
PARP12ENSG00000059378.81501.209101067.365600.492003.446901.34800K562IGF2BP1
PARP12ENSG00000059378.8848.00800646.283700.391803.175602.18230K562MATR3
PARP12ENSG00000059378.8672.13260503.323100.417202.885501.98960K562METAP2
PARP12ENSG00000059378.81069.25680846.804100.336403.715602.78950K562MTPAP
PARP12ENSG00000059378.81492.00400940.847300.6651017.6620015.99910K562NSUN2
PARP12ENSG00000059378.8440.65460576.19270-0.386902.302401.41420K562PCBP2
PARP12ENSG00000059378.8473.15410649.26020-0.456503.041802.25430K562PRPF8
PARP12ENSG00000059378.82064.166301602.775700.364903.916402.62720K562PUM1
PARP12ENSG00000059378.81258.65380980.055300.360802.463601.94440K562PUS1
PARP12ENSG00000059378.81138.96250954.832500.254301.907001.39890K562RBM15
PARP12ENSG00000059378.8840.18400618.100700.442803.788002.62510K562RCC2
PARP12ENSG00000059378.8659.28700490.489100.426602.381801.48440K562SF3B1
PARP12ENSG00000059378.8823.83670616.869100.417303.434802.65240K562SRSF1
PARP12ENSG00000059378.81218.71230952.157000.356002.881201.68720K562SRSF7
PARP12ENSG00000059378.81213.64610997.602600.282702.894002.15920K562UPF1
PARP12ENSG00000059378.81369.01630853.613400.6814010.086208.37590K562WDR3
PARP12ENSG00000059378.81199.59960887.683800.434306.578205.32410K562WDR43
PARP12ENSG00000059378.81693.984401332.244100.346503.017602.11110K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for PARP12 is not available on ENCORE database.





10 RBPs can affect the splicing of PARP12 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEPARP12ENSG00000059378.8chr7-1397337741397338811397284121397284881397340341397341310.147000.000100.06041includedK562TAF15
SEPARP12ENSG00000059378.8chr7-1397337741397338811397284121397284881397340341397341310.122000.001300.02583includedK562SF3B4
SEPARP12ENSG00000059378.8chr7-139737514139737656139734034139734131139746683139746807-0.290000.001700.03199excludedHepG2U2AF1
SEPARP12ENSG00000059378.8chr7-1397574101397575731397566551397569531397576981397578500.057000.000360.00508includedK562AQR
SEPARP12ENSG00000059378.8chr7-1397337741397338811397284121397284881397340341397341310.093000.008940.09667includedK562PUS1
SEPARP12ENSG00000059378.8chr7-139737514139737656139734034139734131139741443139741639-0.093000.007700.08609excludedK562PUS1
SEPARP12ENSG00000059378.8chr7-1397337741397338811397284121397284881397340341397341310.088000.002650.05006includedK562U2AF1
SEPARP12ENSG00000059378.8chr7-139737514139737656139734034139734131139741443139741639-0.476000.000360.00858excludedK562U2AF2
SEPARP12ENSG00000059378.8chr7-1397337741397338811397284121397284881397340341397341310.124000.003820.07603includedK562AGGF1
SEPARP12ENSG00000059378.8chr7-139737514139737656139734034139734131139741443139741639-0.123000.005270.09688excludedK562AGGF1
SEPARP12ENSG00000059378.8chr7-1397337741397338811397284121397284881397340341397341310.223000.000000.00516includedK562PABPC4
SEPARP12ENSG00000059378.8chr7-139737514139737656139734034139734131139741443139741639-0.242000.000110.00297excludedK562HNRNPC
A3SSPARP12ENSG00000059378.8chr7-1397375141397377611397375141397376561397414431397416390.382000.000000.00000longerHepG2U2AF2
A3SSPARP12ENSG00000059378.8chr7-1397259961397262091397259961397261481397270751397272060.058000.008220.04465longerK562AQR
MXEPARP12ENSG00000059378.8chr7-1397375141397376561397466831397468071397340341397341311397544611397545630.193000.005560.078281includedHepG2U2AF1
MXEPARP12ENSG00000059378.8chr7-139727075139727206139728412139728488139725996139726148139734034139734131-0.220000.000980.036372includedK562AGGF1
MXEPARP12ENSG00000059378.8chr7-139737514139737656139741443139741639139734034139734131139746683139746807-0.288000.000070.000872includedHepG2U2AF2
MXEPARP12ENSG00000059378.8chr7-139737514139737656139746683139746807139734034139734131139754461139754563-0.262000.016910.081742includedHepG2U2AF2
MXEPARP12ENSG00000059378.8chr7-139734034139734131139746683139746807139728412139728488139754461139754563-0.313000.019160.089692includedHepG2U2AF2
MXEPARP12ENSG00000059378.8chr7-1397375141397376561397414431397416391397340341397341311397544611397545630.217000.000180.005131includedK562HNRNPC
MXEPARP12ENSG00000059378.8chr7-139741443139741639139746683139746807139734034139734131139754461139754563-0.279000.001050.021472includedK562HNRNPC
MXEPARP12ENSG00000059378.8chr7-1397284121397284881397340341397341311397270751397272061397414431397416390.101000.003170.090671includedK562AKAP8L

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for PARP12 is not avaliable on ENCORE database.