MTG2

General Information

Gene Name       : MTG2
Gene ID             : ENSG00000101181.17
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: MTG2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878MTG2ENSG00000101181.176.5421.3413.94ENCSR000AEF
HepG2MTG2ENSG00000101181.1731.4620.9926.23ENCSR985KAT
K562MTG2ENSG00000101181.1748.0436.2342.13ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for MTG2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • MTG2 RNA is bound by 19 proteins.  







eCLIP assay for MTG2 is not avaliable on ENCORE database.





19 proteins are bound to MTG2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr206077301160773076+3'-UTR,CDS,intron-Distal,intron-Proximal3.738669.09021HepG2PRPF8
chr206077301960773111+3'-UTR,CDS,intron-Distal,intron-Proximal4.284594.52312K562AQR
chr206077622860776327+3'-UTR4.311264.20997HepG2UPF1
chr206077087360771003+3'-UTR,CDS4.253306.72914HepG2SRSF1
chr206077290760773031+3'-UTR,CDS,intron-Distal,intron-Proximal4.7427212.76865HepG2PPIG
chr206077100460771023+3'-UTR,CDS,intron-Proximal5.416117.81430K562AQR
chr206077364060773731+3'-UTR,CDS,intron-Distal,intron-Proximal3.794625.48218HepG2SF3B4
chr206077383360773912+3'-UTR,CDS,intron-Distal,intron-Proximal3.538724.24993HepG2PPIG
chr206076845360768533+3'-UTR,CDS,intron-Distal,intron-Proximal4.7249910.67832HepG2U2AF2
chr206077694460777100+3'-UTR5.1388716.13372K562UPF1
chr206077688460776944+3'-UTR4.271967.50817K562UPF1
chr206077368460773760+3'-UTR,CDS,intron-Distal,intron-Proximal3.621097.09278HepG2PPIG
chr206077096060771072+3'-UTR,CDS,intron-Proximal3.5052210.37477HepG2PRPF8
chr206077722860777289+3'-UTR3.871415.61622K562UPF1
chr206075809260758203+5'-UTR,intron-Proximal5.173416.92972HepG2NCBP2
chr206075819960758279+intron-Distal,intron-Proximal3.6020010.16757HepG2CSTF2T
chr206076823960768319+intron-Distal3.701936.17334HepG2U2AF2
chr206075826060758303+intron-Distal7.5065831.33135HepG2EFTUD2
chr206076512360765236+intron-Distal4.188687.32988HepG2HNRNPM
chr206075819960758295+intron-Distal,intron-Proximal5.5627612.24709HepG2GTF2F1
chr206075820160758219+intron-Distal,intron-Proximal5.3448012.16529HepG2PRPF4
chr206075819660758270+intron-Distal,intron-Proximal3.105905.93037K562EFTUD2
chr206075821960758279+intron-Distal4.3376910.59452HepG2PRPF4
chr206075820160758287+intron-Distal,intron-Proximal5.045687.33617K562GTF2F1
chr206076215260762242+intron-Distal3.741943.59301K562HNRNPM
chr206075819360758260+intron-Distal,intron-Proximal6.6535460.75028HepG2EFTUD2
chr206075815060758263+intron-Distal,intron-Proximal3.047323.95571K562DROSHA
chr206075820160758274+intron-Distal,intron-Proximal4.029173.36290K562GEMIN5
chr206075813760758296+intron-Distal,intron-Proximal3.457274.54121HepG2KHSRP
chr206075815160758258+intron-Distal,intron-Proximal3.944643.43867K562CSTF2T
chr206076214060762216+intron-Distal5.504618.95887HepG2HNRNPM
chr206075818760758300+intron-Distal,intron-Proximal3.3633310.07170HepG2FAM120A
chr206075816660758336+intron-Distal,intron-Proximal3.519285.66421K562PRPF8
chr206075818260758258+intron-Distal,intron-Proximal3.037783.60583HepG2CDC40
chr206076221660762295+intron-Distal3.039383.31176HepG2HNRNPM
chr206077103560771113+intron-Distal,intron-Proximal4.205738.98393HepG2RBM22
chr206075812960758201+intron-Proximal3.750487.21436K562GTF2F1
chr206075812260758199+intron-Proximal4.6494126.45158HepG2PRPF4
chr206077102360771053+intron-Proximal5.7348210.44569K562AQR
chr206077567760775731+intron-Proximal4.581715.03032HepG2SF3B4
chr206075812960758199+intron-Proximal4.4179710.01583HepG2GTF2F1
chr206075812960758196+intron-Proximal3.057438.33103HepG2RBM22
chr206075812460758193+intron-Proximal5.2967326.60875HepG2EFTUD2
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for MTG2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for MTG2 is not available on ENCORE database.

  • 80 RBPs can affect the levels of MTG2.  








The Knockdown/knockout RNA-Seq assay for MTG2 is not available on ENCORE database.





80 RBPs can affect the gene expression of MTG2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
MTG2ENSG00000101181.13896.14070666.973700.426002.476201.58360HepG2ABCF1
MTG2ENSG00000101181.13736.02450553.127400.412004.325303.59780HepG2ACO1
MTG2ENSG00000101181.13810.06450514.404300.655004.675904.00690HepG2AKAP1
MTG2ENSG00000101181.13661.12780406.132500.702904.402103.21870HepG2BCCIP
MTG2ENSG00000101181.13922.86820463.394800.9938013.8376012.64460HepG2BOP1
MTG2ENSG00000101181.13581.67700404.360400.524503.414802.56150HepG2CIRBP
MTG2ENSG00000101181.13823.49740552.941200.574508.540007.49530HepG2CKAP4
MTG2ENSG00000101181.13536.20240307.745200.800904.542303.55920HepG2CNOT7
MTG2ENSG00000101181.13750.92370492.712500.607804.599703.80850HepG2DDX3X
MTG2ENSG00000101181.13605.94950399.332800.601503.277502.44610HepG2DDX55
MTG2ENSG00000101181.13539.81900406.877200.407802.089301.56650HepG2EIF2S1
MTG2ENSG00000101181.131029.69970449.592801.1954015.5140014.01570HepG2EIF4A3
MTG2ENSG00000101181.13805.94430540.445700.576405.734504.52940HepG2EWSR1
MTG2ENSG00000101181.13748.48430453.784500.721906.341105.31800HepG2FXR1
MTG2ENSG00000101181.13649.27760420.865300.625404.525403.68330HepG2G3BP1
MTG2ENSG00000101181.13396.31270260.383500.605903.035801.60370HepG2HNRNPA0
MTG2ENSG00000101181.13453.94050324.622400.483602.963502.29680HepG2HNRNPA1
MTG2ENSG00000101181.13627.08000361.098500.796207.625806.52100HepG2HNRNPC
MTG2ENSG00000101181.13768.00750632.292000.280402.077801.45030HepG2HNRNPF
MTG2ENSG00000101181.13715.68250426.365800.747106.976705.90410HepG2HNRNPK
MTG2ENSG00000101181.13862.67960622.623800.470404.362503.47050HepG2IGF2BP1
MTG2ENSG00000101181.13969.78050632.154900.617304.509203.43880HepG2LARP4
MTG2ENSG00000101181.131066.57570453.943601.2323018.0168016.41860HepG2MAGOH
MTG2ENSG00000101181.13601.17880456.457600.397201.939201.40620HepG2MATR3
MTG2ENSG00000101181.13317.13890469.41340-0.565702.492301.57610HepG2MTPAP
MTG2ENSG00000101181.13343.89740457.59400-0.412102.537501.37620HepG2NAA15
MTG2ENSG00000101181.13841.41250467.188000.848708.268607.20200HepG2NCBP2
MTG2ENSG00000101181.13864.80220556.794600.635105.358204.30340HepG2NOL12
MTG2ENSG00000101181.13266.21400408.05030-0.616203.430102.59690HepG2NSUN2
MTG2ENSG00000101181.13547.66590415.961700.396702.069001.43660HepG2PABPC4
MTG2ENSG00000101181.13453.80080355.041300.354002.304001.52500HepG2PARN
MTG2ENSG00000101181.13936.52590441.847901.0837024.5302023.02480HepG2PCBP1
MTG2ENSG00000101181.13366.29490485.46850-0.406403.006102.20450HepG2PRPF4
MTG2ENSG00000101181.13692.65250449.599000.623407.720906.89810HepG2PTBP1
MTG2ENSG00000101181.13796.95280564.225600.498104.876804.13500HepG2PUM1
MTG2ENSG00000101181.13746.57370563.811800.405003.269402.54050HepG2PUM2
MTG2ENSG00000101181.13699.63440563.386500.312402.647302.04090HepG2PUS1
MTG2ENSG00000101181.13563.35540323.814400.798805.180703.72120HepG2RCC2
MTG2ENSG00000101181.13761.47450500.358700.605707.066106.27080HepG2NELFE
MTG2ENSG00000101181.131053.58690681.183400.629106.599605.60880HepG2RPLP0
MTG2ENSG00000101181.13447.27080313.338500.513302.245301.39200HepG2RPS10
MTG2ENSG00000101181.13494.91100314.241900.655205.275504.45740HepG2RPS19
MTG2ENSG00000101181.13545.14160367.721500.567902.960502.13450HepG2RPS2
MTG2ENSG00000101181.13443.59780309.171300.520702.492901.73190HepG2RPS3A
MTG2ENSG00000101181.13399.65650319.437600.323101.939001.38340HepG2SAFB2
MTG2ENSG00000101181.131184.46750643.467900.880208.151506.94990HepG2SF3A3
MTG2ENSG00000101181.13736.21570468.086600.653308.116407.18530HepG2SF3B4
MTG2ENSG00000101181.13565.78480372.502100.602907.012206.06090HepG2SMN1
MTG2ENSG00000101181.13605.08670325.381600.894907.082005.49780HepG2SMNDC1
MTG2ENSG00000101181.13742.31830524.793400.500205.697804.84580HepG2SRSF5
MTG2ENSG00000101181.13810.27240621.217600.383203.191302.44950HepG2SRSF7
MTG2ENSG00000101181.13853.74260596.831900.516406.838505.93660HepG2SUCLG1
MTG2ENSG00000101181.13298.78710439.16170-0.555601.939001.45520HepG2TAF15
MTG2ENSG00000101181.13685.16510348.493100.9752014.0405013.06550HepG2TIAL1
MTG2ENSG00000101181.13505.08920351.673500.522204.822104.11960HepG2TRIM56
MTG2ENSG00000101181.13788.60980519.268600.602706.116804.74880HepG2TUFM
MTG2ENSG00000101181.13764.62910576.013800.408602.404701.81540HepG2U2AF1
MTG2ENSG00000101181.13349.00200234.793100.571702.941402.16180HepG2UCHL5
MTG2ENSG00000101181.13741.06370550.947100.427604.413203.68560HepG2UTP3
MTG2ENSG00000101181.13510.76190350.753800.542102.735401.68730HepG2XRCC6
MTG2ENSG00000101181.13754.31600627.613900.265202.309001.79580HepG2ZNF622
MTG2ENSG00000101181.131411.856401090.608500.372402.137501.60960K562AQR
MTG2ENSG00000101181.13716.30150536.739800.416203.918302.31210K562DDX27
MTG2ENSG00000101181.131656.584201079.645900.6176012.7854011.49210K562DDX47
MTG2ENSG00000101181.13843.29660512.372500.718703.968202.85930K562EFTUD2
MTG2ENSG00000101181.13540.55420287.132300.9126011.036109.43020K562EIF3G
MTG2ENSG00000101181.13603.83280410.017400.558403.999001.68600K562EIF3H
MTG2ENSG00000101181.13843.02810520.141600.696604.513203.46500K562EIF4A3
MTG2ENSG00000101181.13381.11530505.70550-0.408102.309501.52650K562FMR1
MTG2ENSG00000101181.131065.60740540.922500.9781020.1902018.66840K562FXR1
MTG2ENSG00000101181.1368.02990203.55420-1.581209.985508.48370K562G3BP2
MTG2ENSG00000101181.13906.01850587.087100.625906.796605.90000K562HNRNPC
MTG2ENSG00000101181.13834.368701018.72710-0.288002.352201.52800K562HNRNPU
MTG2ENSG00000101181.13795.92480384.241501.0505016.3047014.12810K562MAGOH
MTG2ENSG00000101181.13536.79340383.417100.485403.620202.55290K562MATR3
MTG2ENSG00000101181.13537.25010341.826000.652205.374704.00100K562PCBP2
MTG2ENSG00000101181.13901.28450498.603800.854007.821806.55530K562PRPF8
MTG2ENSG00000101181.13757.76190373.336701.021208.311907.20200K562PTBP1
MTG2ENSG00000101181.13586.27130824.34270-0.491704.058103.41910K562PUS1
MTG2ENSG00000101181.13642.97700357.824300.845409.395607.69760K562RBM22
MTG2ENSG00000101181.13522.46660376.590500.472203.011701.86720K562NELFE
MTG2ENSG00000101181.13833.14880507.701300.714504.263703.24700K562RPS19
MTG2ENSG00000101181.13537.29580321.356000.741404.656703.31310K562RPS3
MTG2ENSG00000101181.13366.89420211.594400.794006.800505.42330K562SF3B4
MTG2ENSG00000101181.13680.22560366.027500.8940011.053809.65160K562SRSF1
MTG2ENSG00000101181.13422.05480310.229700.444002.377801.41170K562SRSF4
MTG2ENSG00000101181.13551.28550345.767300.672903.272802.11250K562SRSF5
MTG2ENSG00000101181.13102.88390199.80690-0.957603.731201.93560K562TAF15
MTG2ENSG00000101181.13802.67160370.372401.1157010.285408.78240K562TARDBP
MTG2ENSG00000101181.13691.72640357.284800.9530012.8163010.92960K562TIA1
MTG2ENSG00000101181.13569.90280350.771400.700106.176304.38670K562TRA2A
MTG2ENSG00000101181.131270.73580928.338100.452807.367306.04820K562WDR43
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for MTG2 is not available on ENCORE database.





10 RBPs can affect the splicing of MTG2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEMTG2ENSG00000101181.13chr20+6076847160768680607581006075811360770857607710050.249000.000970.01378includedHepG2U2AF2
SEMTG2ENSG00000101181.13chr20+6077250860772583607708576077100560772907607730230.070000.000160.00256includedK562AQR
SEMTG2ENSG00000101181.13chr20+6076847160768680607581006075811360770857607710050.241000.000300.01833includedHepG2SFPQ
MXEMTG2ENSG00000101181.13chr20+6077290760773023607736896077390860770857607710056077417460774313-0.334000.000690.077542includedHepG2FUS
MXEMTG2ENSG00000101181.13chr20+60772907607730236077368960773908607708576077100560774174607743130.376000.000000.000171includedHepG2SRSF1
MXEMTG2ENSG00000101181.13chr20+6077290760773023607736896077390860770857607710056077417460774313-0.204000.002970.038672includedK562DROSHA
MXEMTG2ENSG00000101181.13chr20+60772907607730236077368960773908607708576077100560774174607743130.356000.000250.018491includedHepG2SRSF9
MXEMTG2ENSG00000101181.13chr20+6077290760773023607736896077390860770857607710056077417460774313-0.132000.008130.053552includedK562AQR
MXEMTG2ENSG00000101181.13chr20+6077290760773023607736896077390860770857607710056077417460774313-0.174000.011190.059072includedHepG2U2AF2
MXEMTG2ENSG00000101181.13chr20+60772907607730236077368960773908607708576077100560774174607743130.255000.003640.090441includedHepG2PCBP1
MXEMTG2ENSG00000101181.13chr20+6077290760773023607736896077390860770857607710056077417460774313-0.134000.004320.062512includedK562HNRNPC
MXEMTG2ENSG00000101181.13chr20+6077290760773023607736896077390860770857607710056077417460774313-0.248000.000080.003942includedK562HNRNPUL1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for MTG2 is not avaliable on ENCORE database.