MIER2

General Information

Gene Name       : MIER2
Gene ID             : ENSG00000105556.11
Essential Gene : No

Functions

Localization

Domains (AlphaFold: MIER2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878MIER2ENSG00000105556.116.888.497.69ENCSR000AEF
HepG2MIER2ENSG00000105556.1121.4315.2718.35ENCSR985KAT
K562MIER2ENSG00000105556.1117.5921.8419.71ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for MIER2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • MIER2 RNA is bound by 32 proteins.  







eCLIP assay for MIER2 is not avaliable on ENCORE database.





32 proteins are bound to MIER2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr19306447306596-3'-UTR,intron-Distal4.744625.94150HepG2UPF1
chr19305692305774-3'-UTR,intron-Distal3.361235.25539K562PABPC4
chr19305907305970-3'-UTR,intron-Distal4.875915.36996HepG2PCBP2
chr19305893305972-3'-UTR,intron-Distal4.198954.01415K562LSM11
chr19305703305773-3'-UTR,intron-Distal3.7418111.02176K562UPF1
chr19306567306623-3'-UTR,intron-Distal4.092754.53890K562PCBP1
chr19305896305967-3'-UTR,intron-Distal3.230873.84340K562CSTF2T
chr19306207306318-3'-UTR,intron-Distal4.144973.64119HepG2UPF1
chr19306419306464-3'-UTR,intron-Distal3.802664.82552K562UPF1
chr19305911305983-3'-UTR,intron-Distal4.697046.60136K562PCBP1
chr19305885305971-3'-UTR,intron-Distal4.3288912.07826K562UPF1
chr19306175306237-3'-UTR,intron-Distal4.892946.02674K562UPF1
chr19305887305982-3'-UTR,intron-Distal3.361593.28764HepG2LARP4
chr19308490308585-CDS,intron-Distal,intron-Proximal4.9110811.42662K562AQR
chr19325635325658-CDS,intron-Distal3.166683.50696K562BUD13
chr19313573313645-CDS,intron-Distal,intron-Proximal3.708604.51003HepG2PPIG
chr19325584325637-CDS,intron-Distal,intron-Proximal4.837775.93128HepG2PRPF8
chr19308654308824-CDS,intron-Distal,intron-Proximal3.716615.70176HepG2AQR
chr19325632325669-CDS,intron-Distal,intron-Proximal3.723455.40651HepG2PPIG
chr19326597326681-CDS,intron-Distal,intron-Proximal4.066949.73169K562SF3B4
chr19326585326667-CDS,intron-Distal,intron-Proximal4.895069.23542K562EFTUD2
chr19334365334418-CDS,intron-Distal,intron-Proximal5.484168.04585HepG2PRPF8
chr19334537334609-CDS,intron-Distal,intron-Proximal4.100693.98315HepG2SF3B4
chr19313511313559-CDS,intron-Distal3.978934.13746HepG2PPIG
chr19308513308667-CDS,intron-Distal,intron-Proximal4.7358712.24889HepG2PRPF8
chr19313613313650-CDS,intron-Distal,intron-Proximal3.508713.91614K562BUD13
chr19327070327152-CDS,intron-Distal,intron-Proximal4.056136.35873K562PRPF8
chr19313614313697-CDS,intron-Distal,intron-Proximal4.137223.56713HepG2SF3B4
chr19307503307536-CDS,intron-Distal3.996163.28461K562BUD13
chr19308597308654-CDS,intron-Distal3.393963.93645HepG2PPIG
chr19344760344777-CDS,intron-Distal3.645306.95612HepG2PRPF8
chr19327086327158-CDS,intron-Distal,intron-Proximal3.246125.64457HepG2PRPF8
chr19334324334380-intron-Distal,intron-Proximal3.915684.86737HepG2RBM22
chr19308948309025-intron-Distal,intron-Proximal4.098266.24865HepG2SF3B4
chr19323504323664-intron-Distal6.6861627.07845K562TARDBP
chr19310095310155-intron-Distal4.643375.72853HepG2HNRNPM
chr19338431338522-intron-Distal3.862444.85046K562NONO
chr19310767310807-intron-Distal4.167504.51377K562HNRNPM
chr19326939326991-intron-Distal4.114913.00996K562BUD13
chr19310628310767-intron-Distal4.6026610.04913K562HNRNPM
chr19308306308400-intron-Distal3.362283.51682HepG2RBFOX2
chr19344397344489-intron-Distal4.088337.75469HepG2EFTUD2
chr19310293310347-intron-Distal4.795897.46888K562NONO
chr19342016342092-intron-Distal4.437244.98766K562EWSR1
chr19334338334400-intron-Distal,intron-Proximal4.562237.53589K562AQR
chr19310180310227-intron-Distal4.556005.66217K562NONO
chr19322719322835-intron-Distal4.035718.30477K562EIF4G2
chr19336554336601-intron-Distal3.001893.14895K562NONO
chr19338542338629-intron-Distal4.341318.71921HepG2HNRNPM
chr19338659338748-intron-Distal3.897454.28420HepG2HNRNPM
chr19341915341949-intron-Distal4.733665.72853HepG2HNRNPM
chr19311031311085-intron-Distal4.318714.78076K562HNRNPM
chr19322558322668-intron-Distal4.633416.40241K562NONO
chr19344439344490-intron-Distal4.767724.63331HepG2XRN2
chr19323665323727-intron-Distal3.873095.80877K562EXOSC5
chr19337127337243-intron-Distal3.166334.96160K562KHSRP
chr19322835322943-intron-Distal4.260736.72905K562EIF4G2
chr19344379344487-intron-Distal3.618177.08819K562GEMIN5
chr19323011323100-intron-Distal5.7957413.98914K562TARDBP
chr19327077327133-intron-Distal,intron-Proximal4.514316.48405K562AQR
chr19323370323504-intron-Distal5.9658418.67143K562TARDBP
chr19326598326654-intron-Distal,intron-Proximal3.241323.12941K562UCHL5
chr19322899323045-intron-Distal5.9003214.31968K562EXOSC5
chr19323159323220-intron-Distal5.2751511.05400K562TARDBP
chr19310898310965-intron-Distal4.945596.62732K562HNRNPM
chr19341894341954-intron-Distal4.354518.56038K562HNRNPM
chr19310437310496-intron-Distal4.138148.65415K562NONO
chr19310823310877-intron-Distal4.238363.27946HepG2HNRNPM
chr19344125344201-intron-Distal4.155844.33692K562NONO
chr19310254310354-intron-Distal5.127197.14250K562HNRNPM
chr19335867335903-intron-Distal3.723703.07008K562NONO
chr19331313331343-intron-Distal4.066404.28548HepG2HNRNPC
chr19343046343089-intron-Distal3.264613.54602K562TIA1
chr19310684310775-intron-Distal3.276873.93303HepG2HNRNPM
chr19344322344373-intron-Distal3.847165.59508HepG2NKRF
chr19310814310878-intron-Distal4.894367.14250K562HNRNPM
chr19341804341883-intron-Distal3.556785.05066K562HNRNPM
chr19344736344774-intron-Distal5.215047.81134HepG2AQR
chr19331343331364-intron-Distal3.990404.04710HepG2HNRNPC
chr19308667308789-intron-Distal,intron-Proximal4.455289.76577HepG2PRPF8
chr19338578338626-intron-Distal4.007023.01445K562EXOSC5
chr19310083310164-intron-Distal4.080765.07081HepG2XPO5
chr19338539338629-intron-Distal3.975506.26760K562HNRNPM
chr19308446308534-intron-Distal,intron-Proximal4.543564.24431HepG2RBFOX2
chr19322714322825-intron-Distal4.897066.67086K562NONO
chr19324918325109-intron-Distal4.679976.93811K562NONO
chr19323664323746-intron-Distal5.8305816.27819K562TARDBP
chr19344728344760-intron-Distal3.761776.65114HepG2PRPF8
chr19342018342096-intron-Distal3.421423.48567K562SLTM
chr19323959324033-intron-Distal5.299159.32163K562TARDBP
chr19309489309587-intron-Distal4.070893.60944K562TARDBP
chr19307072307119-intron-Distal,intron-Proximal4.603314.65563K562AQR
chr19341908341972-intron-Distal3.274363.61506K562NONO
chr19327807327864-intron-Distal,intron-Proximal3.768384.49024K562AQR
chr19309125309257-intron-Distal3.354513.73797K562CSTF2T
chr19322813322874-intron-Distal3.9551910.18626HepG2HNRNPM
chr19322728322796-intron-Distal4.482445.58025K562HNRNPM
chr19322803322917-intron-Distal4.6059712.37056K562HNRNPM
chr19323559323648-intron-Distal4.846055.12432K562EXOSC5
chr19322886322973-intron-Distal5.8766115.92460K562TARDBP
chr19342012342112-intron-Distal3.755546.00014K562CSTF2T
chr19309370309456-intron-Distal4.189933.60235HepG2HNRNPM
chr19335675335765-intron-Distal3.234464.13948HepG2PRPF4
chr19326028326212-intron-Distal4.161623.34601K562HNRNPK
chr19344135344269-intron-Distal3.155607.11655HepG2NKRF
chr19310292310356-intron-Distal4.648705.37406HepG2HNRNPM
chr19309177309255-intron-Distal3.815753.02711K562EWSR1
chr19309147309254-intron-Distal4.239164.58989K562NONO
chr19310522310628-intron-Distal4.1001811.85281K562NONO
chr19308935309023-intron-Distal,intron-Proximal4.935879.04180K562SF3B4
chr19310649310848-intron-Distal4.9787525.68238K562NONO
chr19336449336542-intron-Distal3.733664.61500HepG2HNRNPM
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for MIER2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for MIER2 is not available on ENCORE database.

  • 86 RBPs can affect the levels of MIER2.  








The Knockdown/knockout RNA-Seq assay for MIER2 is not available on ENCORE database.





86 RBPs can affect the gene expression of MIER2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
MIER2ENSG00000105556.6795.91270531.782400.581707.346406.31550HepG2AUH
MIER2ENSG00000105556.6603.53380465.312400.375103.352302.63300HepG2CKAP4
MIER2ENSG00000105556.6447.08170279.358900.678302.573501.83730HepG2CNOT7
MIER2ENSG00000105556.6638.57820442.106500.530403.636102.37250HepG2CPSF7
MIER2ENSG00000105556.6275.01040194.559600.499202.672501.67400HepG2YBX3
MIER2ENSG00000105556.6138.67910221.98550-0.678702.671901.35040HepG2CSTF2T
MIER2ENSG00000105556.6460.65920314.773400.549304.908204.09630HepG2CELF1
MIER2ENSG00000105556.6480.22740338.386700.504904.909803.96410HepG2DAZAP1
MIER2ENSG00000105556.6148.83710233.95320-0.652503.194902.21140HepG2DDX24
MIER2ENSG00000105556.6379.11220239.900100.660103.123902.30960HepG2DDX55
MIER2ENSG00000105556.6294.95390445.35890-0.594503.232602.51060HepG2DKC1
MIER2ENSG00000105556.6417.10800191.040901.1264013.7705012.29700HepG2DNAJC21
MIER2ENSG00000105556.6361.91180189.356900.9344010.602909.42510HepG2DNAJC2
MIER2ENSG00000105556.6705.02360427.164300.722805.657504.82680HepG2EIF2S1
MIER2ENSG00000105556.6263.70460459.72920-0.801902.988702.27550HepG2EIF4B
MIER2ENSG00000105556.6305.14950214.534400.508202.353301.70890HepG2HNRNPC
MIER2ENSG00000105556.6417.06690308.222600.436203.495702.74580HepG2HNRNPL
MIER2ENSG00000105556.6335.19720213.116000.653305.245704.43180HepG2HNRNPU
MIER2ENSG00000105556.6231.98440421.70320-0.862202.664201.70110HepG2IGF2BP3
MIER2ENSG00000105556.6350.79430217.690800.688206.261605.20200HepG2ILF2
MIER2ENSG00000105556.6322.32760476.69210-0.564501.889601.34250HepG2MAGOH
MIER2ENSG00000105556.6536.57470335.547400.677207.181205.96340HepG2NOL12
MIER2ENSG00000105556.6394.28140220.332400.839402.571601.52160HepG2NONO
MIER2ENSG00000105556.6559.16790255.463901.130107.827106.28620HepG2PABPC1
MIER2ENSG00000105556.6372.68300190.082300.9712010.132808.77150HepG2PPIL4
MIER2ENSG00000105556.6639.76930510.349200.326002.150201.67870HepG2RBM22
MIER2ENSG00000105556.6356.92510503.62750-0.496703.626203.02330HepG2NELFE
MIER2ENSG00000105556.6244.42990367.51610-0.588402.389201.74690HepG2RPLP0
MIER2ENSG00000105556.6386.93360189.788601.0276012.0884010.88870HepG2SAFB2
MIER2ENSG00000105556.6838.72370556.011400.593004.130703.29820HepG2SF3A3
MIER2ENSG00000105556.6479.29640299.467500.678404.965204.04150HepG2SF3B1
MIER2ENSG00000105556.6478.91140307.193800.640507.093906.05370HepG2SLBP
MIER2ENSG00000105556.6307.88410221.324600.476103.012102.34430HepG2SMN1
MIER2ENSG00000105556.6409.72220230.191800.831704.777603.48660HepG2SMNDC1
MIER2ENSG00000105556.6206.60290333.21630-0.689603.033202.21400HepG2SNRNP70
MIER2ENSG00000105556.6819.67810576.399300.507905.944905.28740HepG2SRFBP1
MIER2ENSG00000105556.6332.33580491.76230-0.565304.523803.95590HepG2SRSF1
MIER2ENSG00000105556.6486.09920359.703700.434303.293002.62660HepG2SUCLG1
MIER2ENSG00000105556.6202.15420442.09590-1.1289013.1698012.08210HepG2TAF15
MIER2ENSG00000105556.6429.48160294.991600.541803.187302.41480HepG2TARDBP
MIER2ENSG00000105556.6314.40480207.078300.602303.730903.16890HepG2TIAL1
MIER2ENSG00000105556.6470.96110208.933401.1725017.3745016.12020HepG2TRIM56
MIER2ENSG00000105556.6424.07540312.986300.438102.740501.87140HepG2TUFM
MIER2ENSG00000105556.6823.58840463.817400.828308.105307.03180HepG2U2AF1
MIER2ENSG00000105556.6583.63700295.956200.979602.746501.76030HepG2U2AF2
MIER2ENSG00000105556.6571.39650331.316100.786202.804901.96250HepG2UBE2L3
MIER2ENSG00000105556.6248.97850141.060100.819604.520603.54880HepG2UCHL5
MIER2ENSG00000105556.6236.24020327.75920-0.472403.013202.31780HepG2ZC3H8
MIER2ENSG00000105556.61132.40620792.343800.515105.107504.37530K562AGGF1
MIER2ENSG00000105556.61181.96500870.753300.440803.753802.57050K562AKAP8
MIER2ENSG00000105556.61243.96010824.491100.593304.657503.80290K562AKAP8L
MIER2ENSG00000105556.61176.17210865.130200.443004.750203.51790K562ATP5C1
MIER2ENSG00000105556.6440.52760310.445100.504803.666702.55460K562BCLAF1
MIER2ENSG00000105556.6705.87600506.169300.479703.002601.49340K562CKAP4
MIER2ENSG00000105556.6343.72570235.518900.545303.194802.04910K562CSTF2
MIER2ENSG00000105556.6612.59470459.576200.414503.407401.91730K562DDX6
MIER2ENSG00000105556.61119.48990887.076800.335602.948102.04010K562DKC1
MIER2ENSG00000105556.6428.49570284.674100.589903.455602.43070K562EFTUD2
MIER2ENSG00000105556.6542.19570413.383100.391202.967001.61800K562EWSR1
MIER2ENSG00000105556.6531.12060373.918300.506203.464902.50730K562FIP1L1
MIER2ENSG00000105556.645.42780157.77960-1.796307.770306.45890K562G3BP2
MIER2ENSG00000105556.6417.15930289.633600.526303.189502.33950K562GPKOW
MIER2ENSG00000105556.6894.20780585.574400.610702.491801.35290K562HNRNPA2B1
MIER2ENSG00000105556.6625.00000275.160901.1835012.227309.59790K562IGF2BP2
MIER2ENSG00000105556.61165.97160837.570800.477105.303403.64980K562MAK16
MIER2ENSG00000105556.6385.25870288.511500.417102.402101.54880K562MATR3
MIER2ENSG00000105556.61293.27890980.137200.399904.289703.11400K562MBNL1
MIER2ENSG00000105556.6796.05800512.312600.635702.601101.64850K562PABPN1
MIER2ENSG00000105556.6393.22310257.222100.612204.059902.86880K562PCBP2
MIER2ENSG00000105556.6558.25380424.468300.395202.007101.31220K562PPIG
MIER2ENSG00000105556.6378.43940277.022600.450002.014601.36930K562PRPF8
MIER2ENSG00000105556.6542.62260357.445200.602104.457703.26560K562PSIP1
MIER2ENSG00000105556.6494.36600280.893300.815508.565907.43890K562PTBP1
MIER2ENSG00000105556.6747.868401055.90260-0.497603.814902.54180K562PUM1
MIER2ENSG00000105556.61069.69240817.515400.387802.929602.37360K562PUS1
MIER2ENSG00000105556.61169.41420796.672800.553604.615603.86960K562RBM15
MIER2ENSG00000105556.6453.27790269.302700.751106.405405.05620K562RBM22
MIER2ENSG00000105556.6391.74440262.549700.577203.473201.85830K562RBM34
MIER2ENSG00000105556.6461.21930326.347200.498902.441201.51380K562RCC2
MIER2ENSG00000105556.6787.38700468.581000.748702.904701.65920K562SF1
MIER2ENSG00000105556.6347.81290163.888101.0855011.035409.26140K562SF3B4
MIER2ENSG00000105556.6990.44610571.337200.793603.547202.00430K562SFPQ
MIER2ENSG00000105556.6853.37880538.046400.665402.507401.35950K562SNRNP200
MIER2ENSG00000105556.6445.27060309.345200.525402.817301.78080K562SRFBP1
MIER2ENSG00000105556.6541.07110275.377400.974309.485908.18520K562SRSF1
MIER2ENSG00000105556.6420.40930275.569600.609303.898102.61980K562SRSF4
MIER2ENSG00000105556.6419.47050260.093800.689405.156503.64190K562SRSF5
MIER2ENSG00000105556.6548.39660278.682000.9765010.295908.79230K562TARDBP
MIER2ENSG00000105556.6506.30170268.824900.913209.766208.11370K562TIA1
MIER2ENSG00000105556.6433.57060263.839600.716505.313203.69300K562TRA2A
MIER2ENSG00000105556.6546.88690365.467600.581403.261602.21510K562TRIM56
MIER2ENSG00000105556.61029.34180794.510100.373503.593802.78280K562UPF1
MIER2ENSG00000105556.6419.42900289.086800.536802.982101.70850K562XRN2
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for MIER2 is not available on ENCORE database.





15 RBPs can affect the splicing of MIER2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEMIER2ENSG00000105556.6chr19-330263330380327863327989334399334542-0.062000.001640.03110excludedK562SRSF1
SEMIER2ENSG00000105556.6chr19-336082336173334399334542344773344778-0.464000.000000.00002excludedHepG2U2AF1
SEMIER2ENSG00000105556.6chr19-336082336173334399334542344773344778-0.292000.000830.02697excludedK562AKAP8L
SEMIER2ENSG00000105556.6chr19-3360823361733343993345423447733447780.295000.000780.04818includedHepG2AKAP1
SEMIER2ENSG00000105556.6chr19-326506326598325634325704327132327256-0.081000.000640.01177excludedK562PUS1
SEMIER2ENSG00000105556.6chr19-336082336173334399334542344773344778-0.249000.005470.06660excludedK562PUS1
SEMIER2ENSG00000105556.6chr19-3360823361733343993345423447733447780.327000.002900.09267includedHepG2MATR3
SEMIER2ENSG00000105556.6chr19-3302633303803278633279893343993345420.061000.000130.03060includedHepG2RBM15
SEMIER2ENSG00000105556.6chr19-336082336173334399334542344773344778-0.238000.002390.06015excludedHepG2SF3A3
SEMIER2ENSG00000105556.6chr19-3360823361733343993345423447733447780.353000.000970.06349includedHepG2IGF2BP3
SEMIER2ENSG00000105556.6chr19-336082336173334399334542344773344778-0.353000.000090.00509excludedK562UTP18
SEMIER2ENSG00000105556.6chr19-330263330380327863327989334399334542-0.067000.001230.04404excludedK562TARDBP
SEMIER2ENSG00000105556.6chr19-336082336173334399334542344773344778-0.384000.000230.01189excludedK562HNRNPU
SEMIER2ENSG00000105556.6chr19-336082336173334399334542344773344778-0.340000.000080.00361excludedK562RBM15
SEMIER2ENSG00000105556.6chr19-336082336173334399334542344773344778-0.307000.001510.03836excludedK562AGGF1
SEMIER2ENSG00000105556.6chr19-336082336173334399334542344773344778-0.528000.000030.00259excludedK562HNRNPK
SEMIER2ENSG00000105556.6chr19-3302633303803278633279893343993345420.246000.000000.00004includedHepG2HNRNPC
SEMIER2ENSG00000105556.6chr19-3302633303803278633279893343993345420.074000.005360.07329includedK562HNRNPC

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for MIER2 is not avaliable on ENCORE database.