MIER1

General Information

Gene Name       : MIER1
Gene ID             : ENSG00000198160.14
Essential Gene : No

Functions

Localization

Domains (AlphaFold: MIER1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878MIER1ENSG00000198160.1420.5018.0919.30ENCSR000AEF
HepG2MIER1ENSG00000198160.147.2812.349.81ENCSR985KAT
K562MIER1ENSG00000198160.1411.8412.4012.12ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for MIER1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • MIER1 RNA is bound by 32 proteins.  







eCLIP assay for MIER1 is not avaliable on ENCORE database.





32 proteins are bound to MIER1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr16741207867412161+3'-UTR,intron-Distal4.112236.59336K562KHSRP
chr16745246667452520+3'-UTR3.163614.26772K562FAM120A
chr16741287267412991+3'-UTR,intron-Distal3.629213.02060K562LIN28B
chr16742374267423776+3'-UTR,CDS3.675815.91739K562UCHL5
chr16745246467452514+3'-UTR3.127235.27768K562DDX6
chr16745246567452504+3'-UTR3.9635311.55613K562PABPC4
chr16745131867451375+3'-UTR,intron-Distal4.6578512.07925K562PUM2
chr16745127967451318+3'-UTR,intron-Distal3.694354.68500K562PUM2
chr16741325467413372+3'-UTR,intron-Distal5.071997.02715K562MATR3
chr16745126167451317+3'-UTR,intron-Distal3.680393.07287K562TIA1
chr16742373967423845+3'-UTR,CDS,intron-Proximal4.4823812.20601HepG2BCLAF1
chr16740568167405786+5'-UTR,CDS,intron-Proximal4.3682214.10841K562AQR
chr16740568167405757+5'-UTR,CDS,intron-Proximal5.1265923.65834K562SF3B4
chr16739606967396128+5'-UTR,CDS,intron-Distal,intron-Proximal3.551047.13280HepG2PRPF8
chr16740569167405755+5'-UTR,CDS,intron-Proximal3.522015.74821K562U2AF1
chr16740569267405763+5'-UTR,CDS,intron-Proximal3.196735.57112K562U2AF2
chr16739190167391968+5'-UTR,CDS,intron-Proximal4.683718.44604HepG2PRPF8
chr16739606367396142+5'-UTR,CDS,intron-Distal,intron-Proximal3.015953.67092K562PRPF8
chr16741188867411981+CDS,intron-Distal,intron-Proximal3.895367.58784HepG2BCLAF1
chr16739608167396094+CDS,intron-Distal,intron-Proximal3.563445.99700HepG2AQR
chr16743860967438643+CDS3.425475.53307K562ZNF622
chr16742378367423887+CDS3.246494.25145K562LIN28B
chr16743654667436652+CDS,intron-Proximal4.014446.81385HepG2BCLAF1
chr16744746567447574+CDS3.771599.75908K562ZNF622
chr16742536167425416+CDS,intron-Proximal3.864278.42226K562PUM2
chr16742383367423907+CDS,intron-Proximal3.047736.62895K562BUD13
chr16741184367411981+CDS,intron-Distal,intron-Proximal3.799843.48245K562SRSF7
chr16743655867436647+CDS,intron-Proximal3.092496.89313K562ZNF622
chr16742453367424552+CDS,intron-Proximal5.264317.89689K562UCHL5
chr16743857967438609+CDS,intron-Proximal3.170594.62864K562ZNF622
chr16742384867423904+CDS,intron-Proximal4.8000310.64218HepG2BCLAF1
chr16745022967450303+CDS,intron-Proximal4.094174.39974K562GPKOW
chr16743733767437374+CDS,intron-Proximal4.054103.38968HepG2BCLAF1
chr16742876567428839+CDS,intron-Proximal3.453163.64266HepG2PPIG
chr16742385267423904+CDS,intron-Proximal3.014566.16392K562GRWD1
chr16741181767411875+CDS,intron-Distal,intron-Proximal3.866373.19080K562U2AF2
chr16743649067436546+CDS,intron-Proximal5.383479.32793HepG2BCLAF1
chr16742536867425406+CDS3.302119.04720K562ZNF622
chr16742539667425427+CDS,intron-Proximal3.795437.54331K562AGGF1
chr16742377567423852+CDS3.7970821.35185K562ZNF622
chr16742534867425423+CDS,intron-Proximal3.431786.39733HepG2AQR
chr16743864367438671+CDS4.824316.64300K562ZNF622
chr16742377567423903+CDS3.987539.56057K562TRA2A
chr16742376467423852+CDS3.524876.17947K562PUM1
chr16742535867425427+CDS,intron-Proximal4.2566010.57092HepG2BCLAF1
chr16745031167450453+CDS,intron-Distal,intron-Proximal5.261627.49561HepG2BCLAF1
chr16742385167423904+CDS,intron-Proximal3.705183.86355HepG2PPIG
chr16741191467411981+CDS,intron-Distal,intron-Proximal3.1220511.72944K562ZNF622
chr16742453367424615+CDS,intron-Proximal4.652308.47938HepG2BCLAF1
chr16742453367424555+CDS,intron-Proximal4.295646.81238K562ZNF622
chr16742877067428844+CDS,intron-Proximal4.416557.97334HepG2BCLAF1
chr16741177967411851+CDS,intron-Distal,intron-Proximal3.924744.57435K562SF3B4
chr16742379467423906+CDS,intron-Proximal4.531094.14322HepG2FXR2
chr16742382567423905+CDS,intron-Proximal3.9252817.98372K562UCHL5
chr16743857967438607+CDS,intron-Proximal4.800625.70640HepG2BCLAF1
chr16742385267423905+CDS,intron-Proximal4.4716819.68521K562ZNF622
chr16741183067411914+CDS,intron-Distal,intron-Proximal3.348539.32936K562ZNF622
chr16743860767438676+CDS,intron-Proximal4.7348310.80414HepG2BCLAF1
chr16742465267424669+CDS,intron-Proximal5.182417.34525K562ZNF622
chr16743739167437422+CDS,intron-Proximal4.526884.70478HepG2BCLAF1
chr16742455267424616+CDS4.3108711.93878K562UCHL5
chr16742460867424667+CDS,intron-Proximal3.6753115.98763K562PUM2
chr16742378467423901+CDS3.282483.32595HepG2TRA2A
chr16742536167425368+CDS,intron-Proximal3.144365.44868K562ZNF622
chr16742386067423904+CDS,intron-Proximal3.616365.01422K562GPKOW
chr16740923067409323+intron-Distal4.2215215.40793K562PTBP1
chr16739685067396936+intron-Distal4.062964.02766HepG2HNRNPC
chr16743540167435489+intron-Distal4.394894.50052K562HNRNPL
chr16742340067423447+intron-Distal3.270074.08064K562KHSRP
chr16743871267438785+intron-Distal,intron-Proximal4.105964.07352K562KHSRP
chr16743551067435587+intron-Distal4.002033.47525K562MATR3
chr16743087167430898+intron-Distal4.386404.96658K562KHSRP
chr16743634567436436+intron-Distal,intron-Proximal3.270074.35650K562KHSRP
chr16739760067397667+intron-Distal4.301124.31871HepG2HNRNPM
chr16739608367396086+intron-Distal,intron-Proximal5.1444720.30984K562AQR
chr16740575767405878+intron-Distal,intron-Proximal4.530784.23889K562TIA1
chr16742552367425655+intron-Distal,intron-Proximal3.167953.78727K562PRPF8
chr16739628167396404+intron-Distal3.859453.48722HepG2PRPF4
chr16739608867396162+intron-Distal,intron-Proximal3.410254.25142K562BUD13
chr16742293967423012+intron-Distal3.030983.21801K562HNRNPM
chr16742301167423130+intron-Distal3.941119.31101K562KHSRP
chr16739608667396169+intron-Distal,intron-Proximal5.1802126.06131K562AQR
chr16742887767428975+intron-Distal,intron-Proximal3.391687.01633K562KHSRP
chr16740919667409298+intron-Distal4.9109812.58145HepG2PTBP1
chr16742425767424342+intron-Distal3.087633.55116K562KHSRP
chr16744864667448771+intron-Distal4.059604.35360K562QKI
chr16739760267397663+intron-Distal4.436814.28571K562HNRNPM
chr16743089867430982+intron-Distal4.2220812.49723K562KHSRP
chr16739609467396126+intron-Distal,intron-Proximal3.756277.17852HepG2AQR
chr16742860867428656+intron-Distal3.156363.28806K562KHSRP
chr16743082867430871+intron-Distal3.170303.68839K562KHSRP
chr16739625167396338+intron-Distal3.100588.30811K562EFTUD2
chr16740565667405681+intron-Proximal5.8065210.98510K562SF3B4
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for MIER1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for MIER1 is not available on ENCORE database.

  • 67 RBPs can affect the levels of MIER1.  








The Knockdown/knockout RNA-Seq assay for MIER1 is not available on ENCORE database.





67 RBPs can affect the gene expression of MIER1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
MIER1ENSG00000198160.101070.02800710.211600.591206.444005.59600HepG2ACO1
MIER1ENSG00000198160.101435.686101102.912800.380302.315101.82410HepG2AKAP1
MIER1ENSG00000198160.10431.50000696.09150-0.689904.583803.37650HepG2BCCIP
MIER1ENSG00000198160.101016.09610831.475900.289202.151701.46620HepG2CALR
MIER1ENSG00000198160.10473.24190603.27680-0.350202.549501.57600HepG2YBX3
MIER1ENSG00000198160.10785.01750941.72840-0.262602.750602.01070HepG2DAZAP1
MIER1ENSG00000198160.10404.09570656.93540-0.701103.846902.88350HepG2DDX19B
MIER1ENSG00000198160.10542.07000727.14220-0.423802.839401.81510HepG2DDX5
MIER1ENSG00000198160.10458.04740587.11040-0.358102.714402.06760HepG2DNAJC2
MIER1ENSG00000198160.101583.233601278.188700.308703.995403.29550HepG2ETF1
MIER1ENSG00000198160.10610.96490949.07520-0.635402.123501.55820HepG2GPKOW
MIER1ENSG00000198160.10396.88610598.11510-0.591704.321603.53800HepG2HNRNPA1
MIER1ENSG00000198160.10610.53230782.81360-0.358603.249302.47740HepG2HNRNPF
MIER1ENSG00000198160.10705.60290857.87490-0.281902.850202.16790HepG2HNRNPL
MIER1ENSG00000198160.10465.05660660.86390-0.506904.409103.65880HepG2HNRNPU
MIER1ENSG00000198160.10520.49650797.02340-0.614704.382202.82550HepG2KHDRBS1
MIER1ENSG00000198160.10697.30080891.37400-0.354202.713802.12260HepG2PUF60
MIER1ENSG00000198160.10814.64390946.19810-0.216002.111501.57970HepG2PUM1
MIER1ENSG00000198160.102022.98310698.458001.5341017.3400015.72110HepG2RAVER1
MIER1ENSG00000198160.10996.84260812.914100.294202.252801.46880HepG2RBM15
MIER1ENSG00000198160.101264.138501068.348900.242702.103801.63610HepG2RBM22
MIER1ENSG00000198160.101118.04210814.873600.456204.457603.61830HepG2RBM25
MIER1ENSG00000198160.101107.26890843.242900.392903.082402.36770HepG2RPLP0
MIER1ENSG00000198160.10636.85240839.92210-0.399302.000201.31980HepG2RPS3A
MIER1ENSG00000198160.10915.76220522.362400.809807.829306.59020HepG2RRP9
MIER1ENSG00000198160.10443.93560588.54780-0.406802.901002.24490HepG2SAFB2
MIER1ENSG00000198160.101008.96470717.865600.491003.057002.34830HepG2SF3A3
MIER1ENSG00000198160.10722.69780854.61740-0.241902.182701.54720HepG2SLBP
MIER1ENSG00000198160.10494.51720711.65280-0.525203.053802.04410HepG2SMNDC1
MIER1ENSG00000198160.102243.695801206.695500.8947032.9350031.70520HepG2SRFBP1
MIER1ENSG00000198160.101128.97930900.927500.325403.494902.97950HepG2SRSF1
MIER1ENSG00000198160.101040.62780732.956800.505607.517106.68880HepG2SRSF9
MIER1ENSG00000198160.10914.18500652.699900.486002.476701.34250HepG2SUB1
MIER1ENSG00000198160.101175.544501000.906700.231902.031101.48220HepG2SUCLG1
MIER1ENSG00000198160.101024.16960809.802400.338703.180802.58550HepG2TAF15
MIER1ENSG00000198160.10468.84840642.27560-0.454103.478402.93120HepG2TIAL1
MIER1ENSG00000198160.10365.60440647.88520-0.825507.012206.18550HepG2TRIM56
MIER1ENSG00000198160.101119.94420668.827800.743608.686407.56680HepG2U2AF1
MIER1ENSG00000198160.10766.29520636.637100.267302.143701.51640HepG2UPF1
MIER1ENSG00000198160.10492.36230614.64800-0.320002.394001.82770HepG2UTP3
MIER1ENSG00000198160.10331.99190670.68730-1.014509.966808.60840HepG2XRN2
MIER1ENSG00000198160.10941.91390700.178800.427805.901205.18050HepG2ZNF622
MIER1ENSG00000198160.101647.879201043.549300.6590014.2274013.04390K562AGGF1
MIER1ENSG00000198160.101757.567501085.853400.694709.997008.65430K562AKAP8L
MIER1ENSG00000198160.102097.918601432.229900.550606.457505.62230K562AQR
MIER1ENSG00000198160.101500.888301139.308500.397604.843403.59850K562ATP5C1
MIER1ENSG00000198160.101005.867201246.18930-0.309102.615301.54020K562CPEB4
MIER1ENSG00000198160.101441.014601168.499600.302303.139102.19830K562DKC1
MIER1ENSG00000198160.101047.67520718.002900.545003.958902.39670K562EEF2
MIER1ENSG00000198160.10686.12770882.29050-0.362803.226501.96070K562EIF4B
MIER1ENSG00000198160.101860.005101514.325300.296503.678102.59480K562EIF4G2
MIER1ENSG00000198160.10667.82060855.19400-0.356802.906501.57950K562EWSR1
MIER1ENSG00000198160.10882.96150682.106600.372303.096601.66880K562FUS
MIER1ENSG00000198160.101574.22320985.794300.675204.364003.43200K562G3BP2
MIER1ENSG00000198160.101844.618201152.386200.678604.032503.01180K562KIF1C
MIER1ENSG00000198160.10665.41380892.17300-0.423103.327502.36620K562METAP2
MIER1ENSG00000198160.101952.97090904.867501.1098013.2610010.80590K562NAA15
MIER1ENSG00000198160.101060.68490675.142100.651604.484203.53020K562PRPF8
MIER1ENSG00000198160.10889.865701249.50860-0.489702.556401.91390K562PTBP1
MIER1ENSG00000198160.103294.116701076.918401.6129048.6892046.33800K562PUS1
MIER1ENSG00000198160.101525.67130940.608600.697703.812502.10970K562RAVER1
MIER1ENSG00000198160.102067.200801049.253500.9782026.4483024.53220K562RBM15
MIER1ENSG00000198160.10398.56560534.54760-0.423502.634701.66880K562RCC2
MIER1ENSG00000198160.10752.399801001.19250-0.412103.225401.38620K562RECQL
MIER1ENSG00000198160.10625.95900889.26700-0.506503.662502.49070K562RPS3
MIER1ENSG00000198160.10927.655101224.83870-0.400901.943801.33900K562SRSF1
MIER1ENSG00000198160.10578.43450858.59990-0.569805.480603.90590K562SRSF4
MIER1ENSG00000198160.10840.71850594.385500.500105.000403.88940K562SYNCRIP
MIER1ENSG00000198160.10847.974901195.89590-0.496002.545401.76450K562TIA1
MIER1ENSG00000198160.101296.67170987.031200.393504.120303.14150K562U2AF2
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for MIER1 is not available on ENCORE database.





3 RBPs can affect the splicing of MIER1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEMIER1ENSG00000198160.10chr1+674385796743867467437276674374196744227767442405-0.242000.000000.00000excludedK562AQR
SEMIER1ENSG00000198160.10chr1+6739457267394646673918246739192567405710674057350.504000.001340.04683includedK562HNRNPU
SEMIER1ENSG00000198160.10chr1+6739457267394646673918246739192567405710674057350.450000.001130.04398includedK562PTBP1
A3SSMIER1ENSG00000198160.10chr1+6743732167437419674373376743741967436490674366420.134000.000000.00000longerK562AQR
A3SSMIER1ENSG00000198160.10chr1+6743855767438674674385796743867467437337674374190.140000.000000.00002longerK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for MIER1 is not avaliable on ENCORE database.