MED25

General Information

Gene Name       : MED25
Gene ID             : ENSG00000104973.17
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: MED25)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878MED25ENSG00000104973.179.0022.0615.53ENCSR000AEF
HepG2MED25ENSG00000104973.1727.5219.5523.54ENCSR985KAT
K562MED25ENSG00000104973.1740.9449.0144.97ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for MED25 is not avaliable on ENCORE database.



Proteins bound to RNA
  • MED25 RNA is bound by 22 proteins.  







eCLIP assay for MED25 is not avaliable on ENCORE database.





22 proteins are bound to MED25 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr195032154550321648+5'-UTR,CDS3.233105.67297HepG2DDX3X
chr195032154850321666+5'-UTR,CDS4.1717512.67554HepG2NCBP2
chr195032155550321652+5'-UTR,CDS3.698475.48399K562DDX3X
chr195033376550333804+CDS,intron-Distal,intron-Proximal3.499724.77136HepG2PPIG
chr195032187250321891+CDS,intron-Proximal5.7218311.02807K562AQR
chr195033519250335261+CDS,intron-Distal,intron-Proximal3.084684.42661HepG2PPIG
chr195033551350335582+CDS,intron-Distal,intron-Proximal3.434478.18279K562SF3B4
chr195032165250321709+CDS3.302294.75208K562DDX3X
chr195033222950332244+CDS,intron-Distal3.149863.59391K562AQR
chr195032240450322463+CDS,intron-Distal,intron-Proximal4.462806.80869K562AQR
chr195033966050339717+CDS,intron-Distal,intron-Proximal5.3082414.81877K562AQR
chr195033945950339494+CDS,intron-Distal,intron-Proximal5.4638523.89296K562AQR
chr195033541350335418+CDS,intron-Distal,intron-Proximal5.1073224.48086K562AQR
chr195033170450331753+CDS,intron-Distal,intron-Proximal4.117073.89948K562YBX3
chr195033539150335412+CDS,intron-Distal5.009744.35676HepG2PRPF8
chr195033163650331744+CDS,intron-Distal,intron-Proximal4.5928513.13232K562SF3B4
chr195033375650333805+CDS,intron-Distal,intron-Proximal4.277343.77802HepG2U2AF2
chr195033554050335595+CDS,intron-Distal,intron-Proximal4.589868.29703HepG2AQR
chr195033315650333202+CDS,intron-Distal4.008196.28735K562DDX24
chr195033375250333808+CDS,intron-Distal,intron-Proximal4.029844.60541K562U2AF1
chr195033221350332267+CDS,intron-Distal,intron-Proximal4.3814414.39919K562SF3B4
chr195033228950332347+CDS,intron-Distal3.969376.36347HepG2PPIG
chr195032251950322543+CDS,intron-Distal4.056563.66655K562YBX3
chr195033831850338440+CDS,intron-Distal,intron-Proximal3.186787.67372HepG2GRWD1
chr195033554950335609+CDS,intron-Distal,intron-Proximal3.6604313.01298HepG2PRPF8
chr195033877750338836+CDS,intron-Distal,intron-Proximal4.667368.01338K562AQR
chr195033949450339535+CDS,intron-Distal4.2367022.09373K562AQR
chr195033920150339210+CDS,intron-Distal,intron-Proximal6.5968419.16919K562AQR
chr195033179850331850+CDS,intron-Distal,intron-Proximal4.445209.80019K562AQR
chr195033555150335587+CDS,intron-Distal,intron-Proximal6.0273123.43520K562AQR
chr195033374650333793+CDS,intron-Distal,intron-Proximal4.239725.68247K562SF3B4
chr195033374950333815+CDS,intron-Distal,intron-Proximal3.732094.79829K562EFTUD2
chr195033540950335458+CDS,intron-Distal,intron-Proximal3.267766.71915K562PRPF8
chr195033467450334719+CDS,intron-Distal,intron-Proximal3.539585.86107HepG2PPIG
chr195033219850332280+CDS,intron-Distal,intron-Proximal3.461518.46496HepG2BUD13
chr195033541350335418+CDS,intron-Distal,intron-Proximal4.9272617.14767HepG2AQR
chr195033541250335458+CDS,intron-Distal,intron-Proximal5.7747332.23479HepG2PRPF8
chr195033819550338253+CDS,intron-Distal,intron-Proximal4.1509514.54031K562SF3B4
chr195033407250334127+CDS,intron-Distal5.136024.48364K562DDX24
chr195033229450332346+CDS,intron-Distal4.720986.85891K562DDX24
chr195033843450338458+intron-Distal,intron-Proximal3.344186.16312K562AQR
chr195033414450334186+intron-Distal,intron-Proximal5.8854111.56697K562AQR
chr195033569050335754+intron-Distal,intron-Proximal4.939587.81156K562BUD13
chr195033323950333290+intron-Distal,intron-Proximal4.276725.68247K562SF3B4
chr195033928550339342+intron-Distal,intron-Proximal3.969395.28701K562PRPF8
chr195032197550322179+intron-Distal3.445184.23595K562AKAP8L
chr195033217550332213+intron-Distal,intron-Proximal5.0699512.22057K562SF3B4
chr195033921050339245+intron-Distal,intron-Proximal6.8123521.35451K562AQR
chr195033541850335444+intron-Distal,intron-Proximal5.7480922.17592HepG2AQR
chr195033541850335472+intron-Distal,intron-Proximal5.8408930.31447K562AQR
chr195033352950333630+intron-Distal,intron-Proximal3.327085.32645HepG2RBFOX2
chr195032225950322338+intron-Distal,intron-Proximal4.256673.19125K562GTF2F1
chr195032679350326876+intron-Distal4.822177.14250K562HNRNPM
chr195032226350322329+intron-Distal5.378176.41139HepG2EFTUD2
chr195032260350322654+intron-Distal,intron-Proximal4.012823.70058K562CSTF2T
chr195033929650339345+intron-Distal,intron-Proximal5.9110812.46873K562AQR
chr195032225050322336+intron-Distal,intron-Proximal3.156294.73673K562CSTF2T
chr195032270550322784+intron-Distal3.576796.23834K562RBFOX2
chr195033570750335787+intron-Distal,intron-Proximal3.489168.10412K562PRPF8
chr195032434250324452+intron-Distal3.402323.84723K562ILF3
chr195032676450326888+intron-Distal4.026144.94813HepG2HNRNPM
chr195032265450322702+intron-Distal4.526835.80843K562CSTF2T
chr195032258350322654+intron-Distal,intron-Proximal5.191769.61270HepG2RBFOX2
chr195033568750335745+intron-Distal,intron-Proximal4.622378.30573K562AQR
chr195033545850335461+intron-Distal,intron-Proximal4.315224.02817HepG2PRPF8
chr195033554150335545+intron-Distal,intron-Proximal5.4887217.79119K562AQR
chr195032264750322764+intron-Distal,intron-Proximal3.402753.84725K562NONO
chr195033014350330214+intron-Distal3.552384.61500HepG2HNRNPM
chr195032258450322658+intron-Distal,intron-Proximal3.607709.79809K562RBFOX2
chr195033364150333746+intron-Distal,intron-Proximal5.3204515.55949K562SF3B4
chr195032572050325832+intron-Distal4.397835.33932K562ILF3
chr195032212950322174+intron-Distal3.791023.17740K562CSTF2T
chr195033554550335551+intron-Distal,intron-Proximal5.6208018.59418K562AQR
chr195033925350339296+intron-Distal,intron-Proximal4.804369.04436K562AQR
chr195032262150322800+intron-Distal,intron-Proximal4.398155.44904K562TARDBP
chr195033544450335458+intron-Distal,intron-Proximal6.3134314.68312HepG2AQR
chr195033845850338476+intron-Distal,intron-Proximal4.278566.77156K562AQR
chr195032199650322193+intron-Distal4.279528.82190HepG2PRPF4
chr195033352350333717+intron-Distal,intron-Proximal5.7093212.20972K562RBFOX2
chr195032271050322759+intron-Distal3.012823.01436K562CSTF2T
chr195032189150321916+intron-Proximal4.411649.80019K562AQR
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for MED25 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for MED25 is not available on ENCORE database.

  • 86 RBPs can affect the levels of MED25.  








The Knockdown/knockout RNA-Seq assay for MED25 is not available on ENCORE database.





86 RBPs can affect the gene expression of MED25 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
MED25ENSG00000104973.10295.32480485.61150-0.717502.975002.17680HepG2CALR
MED25ENSG00000104973.10152.66200238.55410-0.644003.136602.16220HepG2DDX24
MED25ENSG00000104973.10327.78080233.156900.491302.918902.19960HepG2DNAJC21
MED25ENSG00000104973.10409.42110231.098400.825009.535808.41230HepG2DNAJC2
MED25ENSG00000104973.10374.53510559.50700-0.579103.334201.40720HepG2EIF3H
MED25ENSG00000104973.10541.07630791.77190-0.549306.779205.90740HepG2ETF1
MED25ENSG00000104973.10329.16970432.40510-0.393602.253501.53740HepG2FUBP3
MED25ENSG00000104973.10732.78390390.121600.909404.195003.35600HepG2FXR1
MED25ENSG00000104973.10592.84140446.756600.408103.128202.36940HepG2HNRNPF
MED25ENSG00000104973.10649.32170366.754700.824003.199302.44960HepG2HNRNPK
MED25ENSG00000104973.10420.07020332.170900.338602.306501.68310HepG2HNRNPL
MED25ENSG00000104973.10485.69160260.097600.9009011.5194010.35260HepG2HNRNPU
MED25ENSG00000104973.10639.98680401.557900.672301.837401.31500HepG2NCBP2
MED25ENSG00000104973.10467.68690361.615000.371002.525301.79850HepG2NOL12
MED25ENSG00000104973.10613.01590252.400601.2801010.718707.84150HepG2NOLC1
MED25ENSG00000104973.10365.30940254.824300.519503.213901.88710HepG2PKM
MED25ENSG00000104973.10448.95160231.986300.952406.288805.21120HepG2PPIL4
MED25ENSG00000104973.10585.98910394.709400.570005.731105.00100HepG2PTBP1
MED25ENSG00000104973.10537.82890345.211900.639605.603304.79430HepG2PUF60
MED25ENSG00000104973.10524.45860366.479600.517005.535304.75710HepG2PUM1
MED25ENSG00000104973.10505.59770366.198300.465303.510002.75820HepG2PUM2
MED25ENSG00000104973.10111.45480279.32170-1.325502.234101.59520HepG2RAVER1
MED25ENSG00000104973.10421.64530241.066300.806503.767601.71330HepG2RBM14
MED25ENSG00000104973.10385.06370661.76240-0.781209.888409.04560HepG2RBM22
MED25ENSG00000104973.10654.75990439.239400.575906.193905.43890HepG2NELFE
MED25ENSG00000104973.10568.73560409.153900.475003.450302.77140HepG2RECQL
MED25ENSG00000104973.10431.46350299.857200.524902.764002.14940HepG2RPS19
MED25ENSG00000104973.10417.97320278.583500.585202.989602.15920HepG2RPS2
MED25ENSG00000104973.10427.00570231.628400.882305.614304.74960HepG2SAFB2
MED25ENSG00000104973.10573.93500207.926201.464703.823202.17630HepG2SF1
MED25ENSG00000104973.10480.27560331.049400.536705.304404.38540HepG2SLBP
MED25ENSG00000104973.10380.48200270.117700.494103.695602.97050HepG2SMN1
MED25ENSG00000104973.10489.56600340.872800.522204.839204.04920HepG2SRSF5
MED25ENSG00000104973.10340.90700216.901300.652203.157101.97540HepG2STIP1
MED25ENSG00000104973.10597.12200387.643800.623207.834506.87540HepG2SUCLG1
MED25ENSG00000104973.10222.56750385.58590-0.792804.901504.18860HepG2TAF15
MED25ENSG00000104973.10341.62970252.733100.434702.310601.84500HepG2TIAL1
MED25ENSG00000104973.10418.12070254.992700.713407.095906.26510HepG2TRIM56
MED25ENSG00000104973.10544.60060337.293300.691102.116401.36040HepG2TUFM
MED25ENSG00000104973.10598.14310793.96760-0.408602.375401.78940HepG2U2AF1
MED25ENSG00000104973.10562.48370699.47310-0.314502.255901.70350HepG2UTP3
MED25ENSG00000104973.10425.80050562.76920-0.402403.425202.69060HepG2ZC3H8
MED25ENSG00000104973.10627.88000796.80750-0.343703.646103.04180HepG2ZNF622
MED25ENSG00000104973.103022.245201616.699600.9025024.5822023.00440K562AGGF1
MED25ENSG00000104973.102311.738601776.688900.379703.581802.42790K562AKAP8
MED25ENSG00000104973.102708.706601682.293600.687103.392702.66760K562AKAP8L
MED25ENSG00000104973.102363.088001765.214800.420703.017102.06460K562ATP5C1
MED25ENSG00000104973.10711.57260519.715500.453204.408803.17990K562BCLAF1
MED25ENSG00000104973.101253.78900822.309900.608403.010301.90290K562CCAR1
MED25ENSG00000104973.10620.62830394.281700.654406.586004.85160K562CSTF2
MED25ENSG00000104973.101496.086302032.96680-0.442402.905001.90640K562CELF1
MED25ENSG00000104973.101445.621801114.601800.375104.838003.20890K562DDX21
MED25ENSG00000104973.101269.052101579.93460-0.316103.998903.23490K562DDX47
MED25ENSG00000104973.10985.34220800.197100.300202.625801.36420K562DDX6
MED25ENSG00000104973.10740.02560470.540700.653205.017503.76940K562EFTUD2
MED25ENSG00000104973.10935.71960742.584500.333403.088701.84870K562EIF4B
MED25ENSG00000104973.101015.87670719.777000.497005.902803.87200K562EWSR1
MED25ENSG00000104973.101347.15760988.933900.445902.917101.61170K562EXOSC5
MED25ENSG00000104973.10366.56410629.36470-0.779806.793904.89230K562FKBP4
MED25ENSG00000104973.10683.48440857.52660-0.327302.737202.13490K562FXR1
MED25ENSG00000104973.1084.63940279.18370-1.7218014.0154012.14950K562G3BP2
MED25ENSG00000104973.102068.488701088.303000.926405.370503.47210K562HNRNPA2B1
MED25ENSG00000104973.10971.77250486.212200.998904.065302.72150K562IGF2BP2
MED25ENSG00000104973.10729.39380494.425000.560803.839802.38980K562IGF2BP3
MED25ENSG00000104973.102247.825901785.178400.332402.768801.94240K562KIF1C
MED25ENSG00000104973.101109.32210646.324800.779204.742102.66370K562LSM11
MED25ENSG00000104973.10713.15980510.696200.481704.116503.08570K562MAGOH
MED25ENSG00000104973.102719.216701999.872400.443203.804002.70840K562MBNL1
MED25ENSG00000104973.101140.442401448.82630-0.345304.539603.52570K562MTPAP
MED25ENSG00000104973.101152.85660713.610300.691906.724304.23050K562NUSAP1
MED25ENSG00000104973.101804.01240951.880500.922304.754603.36060K562PABPN1
MED25ENSG00000104973.10623.56760454.339600.456702.480401.55730K562PCBP2
MED25ENSG00000104973.102078.185901131.605000.876904.320402.34790K562PPP1R8
MED25ENSG00000104973.101000.19890649.770000.622206.638405.13700K562PSIP1
MED25ENSG00000104973.10632.25700496.195300.349502.399501.77380K562PTBP1
MED25ENSG00000104973.101286.074201918.73100-0.577207.713605.85770K562PUM1
MED25ENSG00000104973.103345.878101668.056301.004109.503008.54580K562PUS1
MED25ENSG00000104973.101348.86680877.376600.620403.689401.43740K562RBFOX2
MED25ENSG00000104973.102699.393901625.532500.7316012.4563011.20100K562RBM15
MED25ENSG00000104973.10947.18510592.910700.675708.156706.45550K562RCC2
MED25ENSG00000104973.101172.82590859.888100.447703.405502.20080K562SAFB
MED25ENSG00000104973.101438.42490870.475000.724502.954901.69670K562SF1
MED25ENSG00000104973.101842.302001061.141600.795802.714501.43090K562SFPQ
MED25ENSG00000104973.101066.48790562.055300.9240013.4159010.73000K562SRFBP1
MED25ENSG00000104973.10629.72870486.469800.372302.424101.75480K562SRSF1
MED25ENSG00000104973.101144.69820662.576400.7887010.900308.69400K562SRSF4
MED25ENSG00000104973.10737.50540459.515700.682406.821905.06380K562SRSF5
MED25ENSG00000104973.10953.76380492.268200.954105.341104.34050K562TARDBP
MED25ENSG00000104973.10860.07760474.866900.8568012.0462010.22400K562TIA1
MED25ENSG00000104973.10860.65920466.153800.884506.076504.31030K562TRA2A
MED25ENSG00000104973.101262.16570664.028600.926505.945404.44070K562TRIM56
MED25ENSG00000104973.101071.767901524.53530-0.508404.018802.56400K562UTP3
MED25ENSG00000104973.101085.321801518.78070-0.484807.720706.37560K562WDR43
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for MED25 is not available on ENCORE database.





15 RBPs can affect the splicing of MED25 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEMED25ENSG00000104973.10chr19+503317055033180450322428503225535033222650332347-0.093000.000030.00216excludedK562AKAP8L
SEMED25ENSG00000104973.10chr19+503317055033180450322428503225535033222650332347-0.060000.003440.04665excludedK562PUS1
SEMED25ENSG00000104973.10chr19+503317055033180450322428503225535033222650332347-0.076000.000450.01860excludedK562UTP18
SEMED25ENSG00000104973.10chr19+503317055033180450322428503225535033222650332347-0.173000.003000.04823excludedK562U2AF2
SEMED25ENSG00000104973.10chr19+5033170550331804503224285032255350332226503323470.060000.000570.02466includedK562HNRNPU
SEMED25ENSG00000104973.10chr19+503317055033180450322428503225535033222650332347-0.146000.000000.00000excludedK562RBM15
SEMED25ENSG00000104973.10chr19+503317055033180450322428503225535033222650332347-0.067000.001040.02872excludedK562AGGF1
SEMED25ENSG00000104973.10chr19+503317055033180450322428503225535033222650332347-0.120000.000000.00010excludedK562SF3B1
A3SSMED25ENSG00000104973.10chr19+5033553450335672503355645033567250335192503354140.104000.000000.00000longerK562AQR
RIMED25ENSG00000104973.10chr19+5033948250340236503394825033966350340103503402360.373000.001370.07053includedK562PPIL4
RIMED25ENSG00000104973.10chr19+5033948250340236503394825033966350340103503402360.203000.000740.00567includedK562PUS1
RIMED25ENSG00000104973.10chr19+5033519250335414503351925033527850335356503354140.067000.000600.01656includedK562RBM22
RIMED25ENSG00000104973.10chr19+503394825034023650339482503396635034010350340236-0.216000.000770.06210excludedK562ZC3H8
RIMED25ENSG00000104973.10chr19+5033519250335414503351925033527850335356503354140.087000.000000.00004includedK562AQR
RIMED25ENSG00000104973.10chr19+5033948250340236503394825033966350340103503402360.257000.011420.06063includedK562AQR
MXEMED25ENSG00000104973.10chr19+5032242850322553503317055033180450321827503218735033222650332347-0.145000.000650.099672includedK562KHDRBS1
MXEMED25ENSG00000104973.10chr19+5032242850322553503317055033180450321827503218735033222650332347-0.179000.000650.018562includedHepG2DDX55
MXEMED25ENSG00000104973.10chr19+5032242850322553503317055033180450321827503218735033222650332347-0.136000.000690.026062includedK562DHX30

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for MED25 is not avaliable on ENCORE database.