MAST2

General Information

Gene Name       : MAST2
Gene ID             : ENSG00000086015.20
Essential Gene : No

Functions

Localization

Domains (AlphaFold: MAST2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878MAST2ENSG00000086015.208.2912.0010.14ENCSR000AEF
HepG2MAST2ENSG00000086015.2024.7617.0520.91ENCSR985KAT
K562MAST2ENSG00000086015.2020.1517.6118.88ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for MAST2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • MAST2 RNA is bound by 28 proteins.  







eCLIP assay for MAST2 is not avaliable on ENCORE database.





28 proteins are bound to MAST2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr14626926246269370+5'-UTR,intron-Distal4.155195.19802K562NCBP2
chr14647396746473997+CDS,intron-Proximal3.229924.44630K562ZNF622
chr14648932146489445+CDS,intron-Distal,intron-Proximal3.243315.13321HepG2RBFOX2
chr14648769746487758+CDS,intron-Proximal3.461565.10069HepG2GRWD1
chr14649638246496431+CDS3.464255.58370HepG2PPIG
chr14648951346489571+CDS3.420054.71371HepG2GRWD1
chr14629510246295146+CDS,intron-Proximal3.726115.55508K562BUD13
chr14634805046348064+CDS3.859825.36555HepG2BCLAF1
chr14649140146491479+CDS3.080344.61799HepG2BCLAF1
chr14647403646474095+CDS,intron-Proximal3.068117.13900K562AQR
chr14647648946476554+CDS,intron-Distal3.076516.46814K562ZNF622
chr14646345046463529+CDS,intron-Proximal3.334433.71649HepG2EFTUD2
chr14649139946491467+CDS3.210353.63043HepG2GRWD1
chr14642505646425071+CDS,intron-Proximal4.723455.27053HepG2PPIG
chr14648863846488701+CDS,intron-Proximal4.424585.93840HepG2PRPF8
chr14649706346497112+CDS4.854964.67689HepG2PPIG
chr14629523946295254+CDS,intron-Proximal3.835373.68471HepG2BCLAF1
chr14648897546489027+CDS,intron-Proximal3.712339.39957HepG2PRPF8
chr14648771546487755+CDS,intron-Proximal3.566134.20387K562ZNF622
chr14629514346295198+CDS4.076436.36347HepG2PPIG
chr14634803246348072+CDS,intron-Proximal4.574775.01214HepG2BUD13
chr14648888146488930+CDS,intron-Proximal4.252467.38067HepG2PRPF8
chr14647638746476443+CDS,intron-Distal,intron-Proximal4.5471213.60231K562U2AF2
chr14647638646476458+CDS,intron-Distal,intron-Proximal3.0360911.92771HepG2U2AF2
chr14634803446348050+CDS,intron-Proximal3.539115.56491HepG2BCLAF1
chr14647401946474059+CDS,intron-Proximal3.309433.75245K562BUD13
chr14650158746501670+CDS4.229344.52184HepG2PABPN1
chr14646345346463566+CDS,intron-Proximal3.6976515.75353K562PRPF8
chr14634803446348071+CDS,intron-Proximal6.2880917.83534HepG2PPIG
chr14648889346489005+CDS,intron-Proximal5.1867810.39778HepG2GRWD1
chr14648890746488992+CDS,intron-Proximal3.883159.16086K562UCHL5
chr14634803546348067+CDS,intron-Proximal3.089214.83973K562ZNF622
chr14649135046491401+CDS3.997666.36347HepG2PPIG
chr14629511146295143+CDS4.590125.56813HepG2PPIG
chr14650146846501537+CDS3.988143.46058HepG2PABPN1
chr14649983546499888+CDS3.810873.06406HepG2IGF2BP1
chr14646344846463554+CDS,intron-Proximal4.2388724.30951K562EFTUD2
chr14649693546496995+CDS,intron-Proximal3.095234.97939HepG2PRPF8
chr14648859046488663+CDS,intron-Proximal4.774637.41350HepG2GRWD1
chr14648949946489565+CDS3.018176.80995K562ZNF622
chr14629520846295255+CDS,intron-Proximal4.4396813.35495HepG2PPIG
chr14649993346499980+CDS,intron-Proximal4.8501513.57653HepG2PRPF8
chr14646346646463524+CDS,intron-Proximal4.733476.23016HepG2PRPF8
chr14649456246494604+CDS3.400533.73423K562UCHL5
chr14648890246488990+CDS,intron-Proximal3.9945810.01989K562ZNF622
chr14646841946468541+CDS,intron-Proximal4.5136810.20178K562SF3B4
chr14648962346489650+CDS4.308005.23082K562DDX24
chr14648884646488951+CDS,intron-Proximal3.101343.29847HepG2AQR
chr14648863946488687+CDS,intron-Proximal4.594054.62947HepG2AQR
chr14629520346295255+CDS,intron-Proximal3.183677.02016K562ZNF622
chr14629510946295180+CDS,intron-Proximal3.7225110.26109HepG2BCLAF1
chr14649692246496960+CDS3.220583.17151K562UCHL5
chr14649706346497112+CDS5.829538.93227K562DDX24
chr14647415446474259+intron-Distal3.851353.45590K562GRWD1
chr14640205546402146+intron-Distal4.313893.60235HepG2HNRNPM
chr14645173646451817+intron-Distal3.620295.83959K562KHSRP
chr14642953546429580+intron-Distal4.719036.08953K562EXOSC5
chr14640180846401886+intron-Distal4.5812110.61559K562EXOSC5
chr14630852446308690+intron-Distal3.368177.08481K562KHSRP
chr14640210746402158+intron-Distal4.214414.02846K562HNRNPM
chr14640194846402002+intron-Distal4.553455.57532K562HNRNPM
chr14643784746437936+intron-Distal3.372768.31866K562PTBP1
chr14636829346368339+intron-Distal5.5218910.67022K562EXOSC5
chr14645148646451671+intron-Distal3.402697.01633K562KHSRP
chr14642405346424147+intron-Distal4.450824.30178K562PTBP1
chr14642418646424290+intron-Distal5.224637.34252HepG2PCBP2
chr14643783346437977+intron-Distal4.471353.80189K562ZC3H8
chr14643784946437940+intron-Distal4.7371820.72497HepG2DKC1
chr14636943246369474+intron-Distal4.111313.30687K562EXOSC5
chr14640228446402329+intron-Distal3.465794.02241K562EXOSC5
chr14631584146315884+intron-Distal4.743985.76606K562EXOSC5
chr14640212746402159+intron-Distal3.761093.72904K562EXOSC5
chr14636810346368175+intron-Distal5.9332415.65517K562EXOSC5
chr14636821146368245+intron-Distal5.6775411.66401K562EXOSC5
chr14627438246274453+intron-Distal3.508313.59771HepG2QKI
chr14640118846401230+intron-Distal4.509025.44433K562EXOSC5
chr14630167746301803+intron-Distal3.285923.73266K562KHSRP
chr14631616446316185+intron-Distal4.614775.44508K562EXOSC5
chr14643783346438012+intron-Distal5.8216627.69646K562SMNDC1
chr14637910446379211+intron-Distal3.941183.34098HepG2HNRNPM
chr14635042446350484+intron-Distal3.437375.01093HepG2QKI
chr14626977946269916+intron-Distal,intron-Proximal3.372194.20198HepG2FAM120A
chr14637358346373710+intron-Distal4.4975912.03011K562KHSRP
chr14645181746451893+intron-Distal3.233064.35650K562KHSRP
chr14631623146316257+intron-Distal4.422064.48560K562EXOSC5
chr14643785046438009+intron-Distal3.032206.00009K562SF3B4
chr14631652546316569+intron-Distal4.351057.61413K562EXOSC5
chr14645588246455997+intron-Distal3.827803.49011K562KHSRP
chr14640149846401535+intron-Distal4.686976.08869K562EXOSC5
chr14641618746416256+intron-Distal3.986273.26547HepG2HLTF
chr14631750946317525+intron-Distal3.957253.01445K562EXOSC5
chr14640075546400788+intron-Distal3.903793.01456K562EXOSC5
chr14643794446438010+intron-Distal5.1402711.08459HepG2DKC1
chr14637344746373536+intron-Distal3.995403.26999K562KHSRP
chr14647524146475385+intron-Distal3.2324112.17204K562KHSRP
chr14631691246316950+intron-Distal4.299503.89085K562EXOSC5
chr14631737146317422+intron-Distal4.091987.01333K562EXOSC5
chr14640084546400887+intron-Distal4.581215.44433K562EXOSC5
chr14631640046316446+intron-Distal4.807476.08953K562EXOSC5
chr14636755946367593+intron-Distal3.794479.14798K562EXOSC5
chr14637611046376233+intron-Distal4.166043.47043HepG2KHSRP
chr14630822346308330+intron-Distal3.483205.35459K562KHSRP
chr14641573646415847+intron-Distal3.940283.12651K562SAFB2
chr14637371046373767+intron-Distal4.068534.54401K562KHSRP
chr14631629846316377+intron-Distal4.419236.41051K562EXOSC5
chr14631712746317186+intron-Distal5.6655711.99379K562EXOSC5
chr14636740846367467+intron-Distal5.9324115.32150K562EXOSC5
chr14636841446368456+intron-Distal5.7367313.65405K562EXOSC5
chr14636839446368474+intron-Distal4.596464.90578HepG2HNRNPM
chr14643793646438012+intron-Distal3.240427.89798K562PTBP1
chr14631713346317220+intron-Distal4.318714.78076K562HNRNPM
chr14640132246401385+intron-Distal4.989785.44433K562EXOSC5
chr14631699846317035+intron-Distal4.815356.73731K562EXOSC5
chr14642421946424288+intron-Distal4.190813.74583HepG2PTBP1
chr14636785846367880+intron-Distal4.961537.71312K562EXOSC5
chr14636753346367559+intron-Distal4.068457.31365K562EXOSC5
chr14647414546474197+intron-Distal3.053363.84771K562ZNF622
chr14642418646424299+intron-Distal3.609563.30744K562PTBP1
chr14640198146402017+intron-Distal4.375503.89080K562EXOSC5
chr14640157546401620+intron-Distal4.812746.41304K562EXOSC5
chr14642518346425291+intron-Distal,intron-Proximal4.233595.19823K562KHSRP
chr14636842346368496+intron-Distal4.497944.02846K562HNRNPM
chr14637846446378543+intron-Distal4.274484.17759HepG2QKI
chr14637610646376300+intron-Distal3.9224311.75440K562KHSRP
chr14646855546468564+intron-Proximal4.353343.70761K562AQR
chr14648864346488710+intron-Proximal5.0567512.21485K562AQR
chr14647406846474097+intron-Proximal4.202103.77023K562ZNF622
chr14649563946495676+intron-Proximal3.747768.39123HepG2PRPF8
chr14646856446468595+intron-Proximal4.527314.13847K562AQR
chr14649993846499980+intron-Proximal5.221837.28294K562AQR
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for MAST2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for MAST2 is not available on ENCORE database.

  • 89 RBPs can affect the levels of MAST2.  








The Knockdown/knockout RNA-Seq assay for MAST2 is not available on ENCORE database.





89 RBPs can affect the gene expression of MAST2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
MAST2ENSG00000086015.16881.250801563.53670-0.827208.839907.94910HepG2AKAP1
MAST2ENSG00000086015.162034.027101454.252300.484009.196007.90150HepG2AKAP8L
MAST2ENSG00000086015.161622.907001212.415700.420603.924103.22420HepG2BOP1
MAST2ENSG00000086015.161707.173501338.648900.350702.999701.71810HepG2BUD13
MAST2ENSG00000086015.16834.166901631.45900-0.967805.484504.40360HepG2CNOT7
MAST2ENSG00000086015.161962.242501335.978700.5545010.464109.36970HepG2CELF1
MAST2ENSG00000086015.161250.247901436.58450-0.200402.256901.57780HepG2DAZAP1
MAST2ENSG00000086015.161160.645101338.69170-0.205902.094501.36090HepG2DDX19B
MAST2ENSG00000086015.16815.906501093.61390-0.422603.878502.78500HepG2DDX24
MAST2ENSG00000086015.161903.292201263.954600.590502.937401.93110HepG2DDX59
MAST2ENSG00000086015.162451.976001286.631900.9302012.4129011.21640HepG2DDX6
MAST2ENSG00000086015.161064.380301384.83000-0.379704.987504.12760HepG2DKC1
MAST2ENSG00000086015.161169.34340901.425700.375302.745902.04450HepG2DNAJC21
MAST2ENSG00000086015.16764.754701029.02920-0.428202.317501.31090HepG2AGO1
MAST2ENSG00000086015.162024.347201236.817600.710708.622307.61190HepG2EIF2S1
MAST2ENSG00000086015.161794.416301355.387900.404703.135001.88430HepG2EIF2S2
MAST2ENSG00000086015.162532.544701330.823600.9282010.023708.75590HepG2EIF4B
MAST2ENSG00000086015.161840.236001357.609100.438704.105803.12550HepG2EIF4G2
MAST2ENSG00000086015.16848.716501064.64180-0.327002.428001.35480HepG2FASTKD2
MAST2ENSG00000086015.162565.180401804.321900.507504.307003.36460HepG2FIP1L1
MAST2ENSG00000086015.16795.792301164.27770-0.549003.429002.18460HepG2FUS
MAST2ENSG00000086015.161704.340201379.124600.305402.010701.41750HepG2FXR1
MAST2ENSG00000086015.161842.649901261.691900.546304.932604.09340HepG2GPKOW
MAST2ENSG00000086015.16810.286701012.32590-0.321202.079301.46780HepG2HNRNPC
MAST2ENSG00000086015.161742.170101446.646800.268103.406402.61680HepG2HNRNPF
MAST2ENSG00000086015.161780.718701424.545900.321903.455702.65360HepG2IGF2BP1
MAST2ENSG00000086015.162344.576801300.365600.8503012.6066011.28550HepG2IGF2BP2
MAST2ENSG00000086015.161801.283501387.315300.376602.497701.89540HepG2MATR3
MAST2ENSG00000086015.161636.62060895.439800.870003.256502.06130HepG2NONO
MAST2ENSG00000086015.162523.630101491.579200.758605.190203.94450HepG2PABPC1
MAST2ENSG00000086015.161627.421801264.541500.363902.553401.85660HepG2PABPC4
MAST2ENSG00000086015.161601.683701357.613400.238402.502401.91850HepG2PCBP1
MAST2ENSG00000086015.16795.953001102.09930-0.469502.514501.52480HepG2PCBP2
MAST2ENSG00000086015.161166.05090896.932500.378503.590902.76170HepG2PPIL4
MAST2ENSG00000086015.161019.26770751.401000.439802.425701.66770HepG2PRPF8
MAST2ENSG00000086015.161792.983101381.436600.376105.683304.95570HepG2PTBP1
MAST2ENSG00000086015.161172.341801442.42080-0.299102.759702.08990HepG2PUM2
MAST2ENSG00000086015.162321.745901496.099700.6339012.2812011.10250HepG2QKI
MAST2ENSG00000086015.161653.423101994.95620-0.270902.428201.61840HepG2RBM15
MAST2ENSG00000086015.16970.857901256.75510-0.372403.054702.01110HepG2RBM27
MAST2ENSG00000086015.161783.042201537.394500.213802.079701.59640HepG2NELFE
MAST2ENSG00000086015.162385.626601558.216000.614409.012707.88980HepG2RPLP0
MAST2ENSG00000086015.16737.020301044.88190-0.503602.715201.77950HepG2RPS10
MAST2ENSG00000086015.161058.748501639.53680-0.630902.648901.86590HepG2RPS3A
MAST2ENSG00000086015.161205.33710895.528700.428505.844504.96300HepG2SAFB2
MAST2ENSG00000086015.162654.023601780.850300.575504.214903.37360HepG2SF3A3
MAST2ENSG00000086015.161483.668101191.759300.316002.330101.67990HepG2SF3B1
MAST2ENSG00000086015.161274.204401044.289400.287002.625201.99530HepG2SMN1
MAST2ENSG00000086015.16862.734201326.04890-0.620103.903902.96780HepG2SNRNP70
MAST2ENSG00000086015.162516.241201754.117200.520409.773808.98880HepG2SRFBP1
MAST2ENSG00000086015.161550.575301342.570800.207701.914601.38100HepG2SRSF5
MAST2ENSG00000086015.162349.514201426.663500.719606.290204.57160HepG2STIP1
MAST2ENSG00000086015.161882.383601526.899400.301904.296903.55340HepG2SUCLG1
MAST2ENSG00000086015.16712.11210970.12600-0.446102.226101.61070HepG2SUPV3L1
MAST2ENSG00000086015.161052.643101349.37440-0.358303.807503.16740HepG2TAF15
MAST2ENSG00000086015.161737.965901173.683200.566306.488205.43990HepG2TARDBP
MAST2ENSG00000086015.161489.825001239.860700.264902.126401.39200HepG2TIA1
MAST2ENSG00000086015.161262.07750985.903700.356202.420101.88540HepG2TRIM56
MAST2ENSG00000086015.161377.96440772.771100.834302.378201.47250HepG2U2AF2
MAST2ENSG00000086015.16850.90250572.989400.570404.076303.15480HepG2UCHL5
MAST2ENSG00000086015.162271.958401524.793000.575208.204007.26180HepG2UTP3
MAST2ENSG00000086015.161017.104901243.41000-0.289803.525002.78120HepG2ZC3H8
MAST2ENSG00000086015.162692.482201736.974100.6323022.6287021.43700HepG2ZNF622
MAST2ENSG00000086015.161352.259401111.063700.283302.975601.98160K562BCLAF1
MAST2ENSG00000086015.161213.23170928.542600.385702.832801.94970K562BOP1
MAST2ENSG00000086015.161275.44650987.182700.369502.933101.84180K562CCAR1
MAST2ENSG00000086015.162178.169701452.997700.584003.277602.10470K562CNOT7
MAST2ENSG00000086015.161308.35440987.229500.406203.999003.05740K562CPSF6
MAST2ENSG00000086015.162269.368201770.407800.358105.026503.35860K562DDX21
MAST2ENSG00000086015.161474.296301134.239000.378203.627802.41600K562DDX3X
MAST2ENSG00000086015.162583.587101973.880000.388206.694805.74580K562DDX47
MAST2ENSG00000086015.161400.213101004.107500.479602.577001.60900K562EIF3A
MAST2ENSG00000086015.161676.401501189.933700.494403.739802.51950K562EIF3D
MAST2ENSG00000086015.16834.60190630.540000.404403.990303.04310K562EIF3G
MAST2ENSG00000086015.161335.952301067.088500.324103.215701.95100K562EIF4B
MAST2ENSG00000086015.163024.795502428.007900.317004.403103.22990K562EIF4G2
MAST2ENSG00000086015.161260.093401004.633000.326802.224101.45530K562FMR1
MAST2ENSG00000086015.16357.99440678.98580-0.923407.843606.52670K562G3BP2
MAST2ENSG00000086015.161153.71590942.499100.291602.005201.32610K562GPKOW
MAST2ENSG00000086015.161370.514001107.097000.307802.433101.37510K562HNRNPF
MAST2ENSG00000086015.16742.472001003.16450-0.434103.114901.79700K562HNRNPK
MAST2ENSG00000086015.161410.120601004.973800.488603.559102.33840K562IGF2BP2
MAST2ENSG00000086015.161279.813201022.009600.324402.517101.39290K562IGF2BP3
MAST2ENSG00000086015.161223.24190920.010500.410903.656002.64100K562METAP2
MAST2ENSG00000086015.161997.167901701.428300.231102.554001.77540K562MTPAP
MAST2ENSG00000086015.162338.767801890.519700.306905.968404.93170K562NSUN2
MAST2ENSG00000086015.161313.692101025.742600.356903.348002.62520K562PTBP1
MAST2ENSG00000086015.161599.099101988.51880-0.314403.366602.72240K562RBM15
MAST2ENSG00000086015.161968.519701323.716700.572403.382201.66920K562SBDS
MAST2ENSG00000086015.162246.044301865.341300.267803.061502.20440K562SF3A3
MAST2ENSG00000086015.162103.620101065.190200.981705.314303.27080K562SFPQ
MAST2ENSG00000086015.161280.25230961.408400.413103.605502.38960K562SRFBP1
MAST2ENSG00000086015.162253.844301911.071700.237903.243502.23760K562SRPK2
MAST2ENSG00000086015.161298.427401005.621100.368603.363302.58880K562SRSF1
MAST2ENSG00000086015.161895.052901579.930200.262302.791901.62110K562SRSF7
MAST2ENSG00000086015.161431.648101047.036200.451303.333302.20900K562SUPV3L1
MAST2ENSG00000086015.161379.10910981.661100.490305.649904.41310K562TIA1
MAST2ENSG00000086015.161347.437701069.116300.333702.176401.35640K562TIAL1
MAST2ENSG00000086015.161393.819701135.837300.295202.182701.35780K562TRIM56
MAST2ENSG00000086015.16480.57520658.09530-0.453502.669501.59950K562U2AF1
MAST2ENSG00000086015.16454.72920679.68970-0.579905.826204.66120K562U2AF2
MAST2ENSG00000086015.162587.821202004.551800.368406.515005.46620K562UPF1
MAST2ENSG00000086015.162062.274101715.242000.265702.218301.43510K562WDR3
MAST2ENSG00000086015.162116.443801783.581600.246803.277302.36320K562WDR43
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for MAST2 is not available on ENCORE database.





5 RBPs can affect the splicing of MAST2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEMAST2ENSG00000086015.16chr1+464944394649460546493402464935354649513746495239-0.323000.000020.00063excludedK562SRSF1
SEMAST2ENSG00000086015.16chr1+464913484649148746489443464896524649340246493535-0.085000.004150.06420excludedK562SF3B4
SEMAST2ENSG00000086015.16chr1+464944394649460546493402464935354649513746495239-0.303000.000970.02040excludedK562SF3B4
SEMAST2ENSG00000086015.16chr1+464944394649460546493402464935354649513746495239-0.226000.001130.02823excludedHepG2SRSF1
A3SSMAST2ENSG00000086015.16chr1+4649133246491487464913484649148746489443464896520.151000.000000.00000longerK562AQR
A5SSMAST2ENSG00000086015.16chr1+4649944246499659464994424649961046499744464999380.087000.000670.01323longerK562AQR
MXEMAST2ENSG00000086015.16chr1+4647640146476611464852674648536946473967464740434648762146487754-0.184000.002820.084262includedHepG2BCCIP
MXEMAST2ENSG00000086015.16chr1+4634803546348067464250574642514946295110462952534646339546463471-0.146000.008760.048602includedHepG2U2AF2

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for MAST2 is not avaliable on ENCORE database.