MAP4K2

General Information

Gene Name       : MAP4K2
Gene ID             : ENSG00000168067.11
Essential Gene : No

Functions

Localization

Domains (AlphaFold: MAP4K2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878MAP4K2ENSG00000168067.1110.1429.1119.62ENCSR000AEF
HepG2MAP4K2ENSG00000168067.1110.374.797.58ENCSR985KAT
K562MAP4K2ENSG00000168067.118.835.707.27ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for MAP4K2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • MAP4K2 RNA is bound by 8 proteins.  







eCLIP assay for MAP4K2 is not avaliable on ENCORE database.





8 proteins are bound to MAP4K2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr116455736564557404-3'-UTR,CDS,intron-Distal5.031735.10740K562DDX24
chr116456952964569596-3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal4.112935.26108K562SF3B4
chr116455939164559465-3'-UTR,CDS,intron-Distal,intron-Proximal4.127573.19682HepG2PABPN1
chr116456918964569242-3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal5.863218.32974K562DDX24
chr116456953964569603-3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal3.214575.33133K562BUD13
chr116456919164569257-3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal4.389206.10653K562SF3B4
chr116456921664569264-3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal3.275873.91614K562BUD13
chr116456862364568704-5'-UTR,CDS,intron-Distal,intron-Proximal4.705718.54916K562SF3B4
chr116456509764565137-5'-UTR,CDS,intron-Distal,intron-Proximal3.403393.34848HepG2PPIG
chr116456681164566884-intron-Distal,intron-Proximal4.131423.31283K562PRPF8
chr116456680064566875-intron-Distal,intron-Proximal4.727076.46853K562EFTUD2
chr116456682664566893-intron-Distal,intron-Proximal4.592934.98250K562AQR
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for MAP4K2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for MAP4K2 is not available on ENCORE database.

  • 75 RBPs can affect the levels of MAP4K2.  








The Knockdown/knockout RNA-Seq assay for MAP4K2 is not available on ENCORE database.





75 RBPs can affect the gene expression of MAP4K2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
MAP4K2ENSG00000168067.7431.83370313.560700.461603.592402.91580HepG2ACO1
MAP4K2ENSG00000168067.7147.62980251.33710-0.767604.224203.02000HepG2ADAR
MAP4K2ENSG00000168067.7713.30390402.378400.825905.426704.71130HepG2AKAP1
MAP4K2ENSG00000168067.7680.05790384.642200.822007.112705.50040HepG2AKAP8
MAP4K2ENSG00000168067.7238.88800332.90700-0.478802.211401.50470HepG2ASCC1
MAP4K2ENSG00000168067.7675.98810459.281100.557504.218703.40290HepG2AUH
MAP4K2ENSG00000168067.7223.93600316.29340-0.498201.956601.30110HepG2CIRBP
MAP4K2ENSG00000168067.7163.01050295.11240-0.856305.042404.13860HepG2CPSF6
MAP4K2ENSG00000168067.7428.96450327.416700.389602.376601.77310HepG2CELF1
MAP4K2ENSG00000168067.7141.86760227.68380-0.682503.289202.28950HepG2DDX24
MAP4K2ENSG00000168067.7129.34950207.96340-0.685102.699601.32890HepG2DDX28
MAP4K2ENSG00000168067.7670.81260385.389500.799505.540204.68280HepG2DDX3X
MAP4K2ENSG00000168067.7400.99520274.557900.546401.988701.32180HepG2DDX55
MAP4K2ENSG00000168067.7791.84150331.195501.2574013.8436012.59380HepG2DDX6
MAP4K2ENSG00000168067.7183.75840299.98970-0.707104.893004.03980HepG2DKC1
MAP4K2ENSG00000168067.7375.19370253.069700.568004.185203.33570HepG2DNAJC21
MAP4K2ENSG00000168067.7138.63480219.63810-0.663803.238802.07900HepG2EIF3G
MAP4K2ENSG00000168067.7165.79660351.63660-1.084706.770405.76790HepG2EIF4A3
MAP4K2ENSG00000168067.7255.28090378.90970-0.569803.447602.23410HepG2ESF1
MAP4K2ENSG00000168067.7817.91490527.381100.633007.150306.25890HepG2ETF1
MAP4K2ENSG00000168067.7297.40920202.496100.554503.284501.99640HepG2FAM120A
MAP4K2ENSG00000168067.7731.65940441.735900.727905.207204.17930HepG2FIP1L1
MAP4K2ENSG00000168067.7513.67420329.197200.641804.235303.42040HepG2G3BP1
MAP4K2ENSG00000168067.7472.10010334.543100.496802.633602.00650HepG2GPKOW
MAP4K2ENSG00000168067.7491.48470299.353900.715208.089706.53280HepG2HDGF
MAP4K2ENSG00000168067.7585.73730333.588200.812107.175906.09090HepG2HNRNPK
MAP4K2ENSG00000168067.7445.68940282.321700.658606.469705.57430HepG2HNRNPU
MAP4K2ENSG00000168067.7593.93620418.460900.505102.569701.37410HepG2KRR1
MAP4K2ENSG00000168067.7411.53380237.195300.794802.500501.49730HepG2METAP2
MAP4K2ENSG00000168067.7686.08430365.451300.908608.428807.35250HepG2NCBP2
MAP4K2ENSG00000168067.7214.80220330.06420-0.619704.418503.68130HepG2PCBP1
MAP4K2ENSG00000168067.7318.54990210.672500.596402.431701.45530HepG2PCBP2
MAP4K2ENSG00000168067.7602.94200333.266200.855209.026708.03400HepG2PUF60
MAP4K2ENSG00000168067.7565.13890363.722700.635705.900705.03720HepG2QKI
MAP4K2ENSG00000168067.7632.37530417.988100.597205.613704.44530HepG2RBM15
MAP4K2ENSG00000168067.7314.57760220.489700.512602.694602.08680HepG2RPS19
MAP4K2ENSG00000168067.7330.71660251.413500.395402.312001.71470HepG2SAFB2
MAP4K2ENSG00000168067.7192.69220314.09600-0.704903.341202.59820HepG2SF3A3
MAP4K2ENSG00000168067.7494.83190349.655900.500904.000703.31140HepG2SF3B4
MAP4K2ENSG00000168067.7359.04660165.974701.113103.435601.93690HepG2SNRNP200
MAP4K2ENSG00000168067.7514.14830351.614300.548102.462201.72580HepG2SNRNP70
MAP4K2ENSG00000168067.7363.69090497.82030-0.452902.687402.19040HepG2SRFBP1
MAP4K2ENSG00000168067.7205.40020340.01110-0.727103.712302.53550HepG2SRSF3
MAP4K2ENSG00000168067.7647.44630329.036600.9764015.4287014.11780HepG2SRSF5
MAP4K2ENSG00000168067.7171.64180432.18410-1.3322011.9794011.05910HepG2SSB
MAP4K2ENSG00000168067.7629.26050374.218300.749709.928708.87250HepG2SUCLG1
MAP4K2ENSG00000168067.7459.74190311.152500.563103.634202.81770HepG2TARDBP
MAP4K2ENSG00000168067.7407.26060274.286900.570204.156903.57120HepG2TIAL1
MAP4K2ENSG00000168067.7366.25540276.783300.404002.582802.03360HepG2TRIM56
MAP4K2ENSG00000168067.7452.03810325.566300.473402.836501.95280HepG2TUFM
MAP4K2ENSG00000168067.7248.08980377.82340-0.606803.497802.79660HepG2U2AF1
MAP4K2ENSG00000168067.7501.32230192.981601.377204.663303.35930HepG2U2AF2
MAP4K2ENSG00000168067.7607.04170278.553901.1237019.9599018.42020HepG2UPF1
MAP4K2ENSG00000168067.7356.75700223.569300.674103.452102.26860HepG2XRCC6
MAP4K2ENSG00000168067.7851.36000550.364900.629308.709907.77810K562AGGF1
MAP4K2ENSG00000168067.7822.95960604.761100.444403.594802.43820K562AKAP8
MAP4K2ENSG00000168067.7778.46910572.678000.442802.595201.96140K562AKAP8L
MAP4K2ENSG00000168067.7293.02570393.08270-0.423801.987301.47510K562AQR
MAP4K2ENSG00000168067.7522.33320337.571900.629706.099704.26390K562DDX21
MAP4K2ENSG00000168067.7465.27970313.381000.570102.991401.90580K562DDX3X
MAP4K2ENSG00000168067.7455.43720317.736300.519304.242602.51770K562DDX6
MAP4K2ENSG00000168067.7413.48090294.874800.487603.696902.32880K562EIF4B
MAP4K2ENSG00000168067.7475.99010295.760800.686406.040204.12800K562EXOSC5
MAP4K2ENSG00000168067.7172.77660340.50660-0.978808.852407.84390K562FXR1
MAP4K2ENSG00000168067.733.78070122.74360-1.861408.828107.41790K562G3BP2
MAP4K2ENSG00000168067.7368.77970218.578900.754505.276504.18780K562GPKOW
MAP4K2ENSG00000168067.7354.50500215.983900.714803.983202.66180K562IGF2BP2
MAP4K2ENSG00000168067.7609.12380415.487100.551805.022104.05760K562NSUN2
MAP4K2ENSG00000168067.7384.66670265.360500.535602.692401.30130K562NUSAP1
MAP4K2ENSG00000168067.7599.33320289.427501.050105.337703.83450K562PABPN1
MAP4K2ENSG00000168067.7363.40010263.119100.465702.702201.30270K562PHF6
MAP4K2ENSG00000168067.7671.00130344.041100.963604.314202.34790K562PPP1R8
MAP4K2ENSG00000168067.7414.04900241.633300.776906.231204.79240K562PSIP1
MAP4K2ENSG00000168067.7343.54600568.99910-0.727902.576501.78980K562PUF60
MAP4K2ENSG00000168067.7844.61420553.373100.609907.193106.26780K562RBM15
MAP4K2ENSG00000168067.7674.58550322.597201.064205.204703.18190K562SFPQ
MAP4K2ENSG00000168067.7303.43620209.002000.537802.673501.67180K562SRFBP1
MAP4K2ENSG00000168067.7372.34970204.108900.867207.086205.29260K562SRSF5
MAP4K2ENSG00000168067.7487.50540301.229800.694507.181105.29080K562SRSF7
MAP4K2ENSG00000168067.7200.00680289.43860-0.533202.859802.02570K562SYNCRIP
MAP4K2ENSG00000168067.7310.19880210.911300.556502.737701.92510K562TIA1
MAP4K2ENSG00000168067.7440.64160232.409000.922807.423005.83060K562TIAL1
MAP4K2ENSG00000168067.7358.49870207.061900.791804.314502.90140K562TRA2A
MAP4K2ENSG00000168067.7376.50430246.921300.608503.120102.10240K562TRIM56
MAP4K2ENSG00000168067.7623.29800472.219400.400403.618202.15680K562TROVE2
MAP4K2ENSG00000168067.753.29930122.78170-1.203905.589804.44800K562U2AF2
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for MAP4K2 is not available on ENCORE database.





9 RBPs can affect the splicing of MAP4K2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
RIMAP4K2ENSG00000168067.7chr11-6456474664565006645647466456485264564972645650060.087000.001220.00887includedK562PUS1
RIMAP4K2ENSG00000168067.7chr11-645647466456500664564746645648526456497264565006-0.170000.000000.00080excludedK562PHF6
RIMAP4K2ENSG00000168067.7chr11-6456474664565006645647466456485264564972645650060.077000.002900.03303includedK562AGGF1
RIMAP4K2ENSG00000168067.7chr11-6456474664565006645647466456485264564972645650060.200000.005510.09401includedHepG2SRSF1
RIMAP4K2ENSG00000168067.7chr11-645647466456500664564746645648526456497264565006-0.193000.000480.04249excludedK562AARS
RIMAP4K2ENSG00000168067.7chr11-6456474664565006645647466456485264564972645650060.122000.000060.00100includedK562AKAP8L
RIMAP4K2ENSG00000168067.7chr11-6456474664565006645647466456485264564972645650060.081000.002070.02381includedK562RBM15
RIMAP4K2ENSG00000168067.7chr11-6456474664565006645647466456485264564972645650060.247000.000510.00729includedHepG2RBM22
RIMAP4K2ENSG00000168067.7chr11-6456474664565006645647466456485264564972645650060.098000.000650.00999includedK562UTP18

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for MAP4K2 is not avaliable on ENCORE database.