LATS1

General Information

Gene Name       : LATS1
Gene ID             : ENSG00000131023.12
Essential Gene : No

Functions

Localization

Domains (AlphaFold: LATS1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878LATS1ENSG00000131023.128.438.068.25ENCSR000AEF
HepG2LATS1ENSG00000131023.128.219.458.83ENCSR985KAT
K562LATS1ENSG00000131023.1220.7619.5820.17ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for LATS1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • LATS1 RNA is bound by 23 proteins.  







eCLIP assay for LATS1 is not avaliable on ENCORE database.





23 proteins are bound to LATS1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr6150001165150001268-3'-UTR,CDS,intron-Distal4.679564.10264K562ZNF622
chr6149997786149997837-3'-UTR,CDS,intron-Distal3.533783.27569HepG2BCLAF1
chr6149997832149997887-3'-UTR,CDS,intron-Distal,intron-Proximal4.007154.52374K562U2AF2
chr6149997690149997710-3'-UTR,CDS,intron-Distal,intron-Proximal4.659553.89826HepG2BCLAF1
chr6149979311149979364-3'-UTR,intron-Distal4.245803.32080HepG2FUBP3
chr6150004855150004901-3'-UTR,CDS,intron-Distal4.3360510.21839K562YBX3
chr6150005289150005356-3'-UTR,CDS,intron-Distal3.051513.24714K562IGF2BP1
chr6149983172149983192-3'-UTR,CDS,intron-Distal4.050097.86788K562YBX3
chr6150004343150004420-3'-UTR,CDS,intron-Distal4.250267.49468HepG2BCLAF1
chr6150004726150004833-3'-UTR,CDS,intron-Distal4.900006.05696K562IGF2BP1
chr6150004472150004520-3'-UTR,CDS,intron-Distal3.463083.36945K562ZNF622
chr6150004241150004294-3'-UTR,CDS,intron-Distal3.764124.17155HepG2BCLAF1
chr6149982541149982579-3'-UTR,intron-Distal4.788745.45041K562PUM2
chr6149979450149979508-3'-UTR,intron-Distal4.808575.08199HepG2FUBP3
chr6150001405150001535-3'-UTR,CDS,intron-Distal4.3376210.89658HepG2BCLAF1
chr6150004602150004677-3'-UTR,CDS,intron-Distal3.285694.20072K562IGF2BP1
chr6150001219150001281-3'-UTR,CDS,intron-Distal3.761626.67313HepG2BCLAF1
chr6149980628149980710-3'-UTR,intron-Distal3.809607.04350HepG2PCBP2
chr6150001402150001493-3'-UTR,CDS,intron-Distal3.348123.13141K562RBM15
chr6150004331150004389-3'-UTR,CDS,intron-Distal4.881556.59793K562UCHL5
chr6150005160150005206-3'-UTR,CDS,intron-Distal3.450864.76162K562IGF2BP2
chr6149979953149980006-3'-UTR,intron-Distal4.640054.32097HepG2FUBP3
chr6150001179150001245-3'-UTR,CDS,intron-Distal4.560054.71804HepG2HLTF
chr6150005065150005155-3'-UTR,CDS,intron-Distal3.054083.17744HepG2GRWD1
chr6149981942149982012-3'-UTR,intron-Distal3.852867.34697K562FAM120A
chr6149982152149982219-3'-UTR,intron-Distal,intron-Proximal4.098795.53799K562FAM120A
chr6150005297150005358-3'-UTR,CDS,intron-Distal3.067183.56709HepG2IGF2BP1
chr6149997830149997890-3'-UTR,CDS,intron-Distal,intron-Proximal3.763997.43659HepG2U2AF2
chr6149980524149980599-3'-UTR,intron-Distal3.027995.18371HepG2HNRNPC
chr6150005139150005231-3'-UTR,CDS,intron-Distal4.5441910.00856K562IGF2BP1
chr6149983192149983208-3'-UTR,CDS,intron-Distal3.930567.44026K562YBX3
chr6150038989150039078-5'-UTR,CDS,intron-Distal4.627514.80730K562FMR1
chr6150023235150023311-5'-UTR,CDS,intron-Distal3.958703.02060K562LIN28B
chr6150038984150039098-5'-UTR,CDS,intron-Distal3.016574.68144K562DDX3X
chr6150023336150023378-5'-UTR,intron-Distal4.251185.21253K562LIN28B
chr6150039013150039090-5'-UTR,CDS,intron-Distal3.917519.23400HepG2DDX3X
chr6150023186150023285-5'-UTR,CDS,intron-Distal,intron-Proximal3.202434.94600K562RBM15
chr6150023285150023377-5'-UTR,intron-Distal3.727284.80676K562RBM15
chr6150023162150023237-CDS,intron-Distal,intron-Proximal4.636055.31233HepG2HLTF
chr6150023073150023151-CDS,intron-Distal,intron-Proximal3.264125.00751HepG2BCLAF1
chr6150022953150023043-CDS,intron-Distal4.931926.37031K562RBM15
chr6150031963150032044-intron-Distal4.6567211.90381HepG2PTBP1
chr6150000874150000960-intron-Distal,intron-Proximal4.848776.58261K562KHSRP
chr6149988521149988577-intron-Distal3.182493.64839HepG2HNRNPC
chr6150000022150000140-intron-Distal3.331504.03817HepG2KHSRP
chr6150000881150000950-intron-Distal,intron-Proximal4.154684.02395HepG2KHSRP
chr6150038900150038985-intron-Distal5.123635.69951K562AQR
chr6150016117150016210-intron-Distal,intron-Proximal4.792564.86944K562AQR
chr6150024924150025114-intron-Distal3.827803.45805K562KHSRP
chr6149985345149985442-intron-Distal4.764596.36200HepG2PTBP1
chr6149995986149996044-intron-Distal3.961643.82619K562ILF3
chr6150031965150032032-intron-Distal4.7014210.02898K562PTBP1
chr6149985337149985457-intron-Distal5.224576.95895K562PTBP1
chr6149995574149995658-intron-Distal4.806216.53303HepG2ILF3
chr6150033024150033138-intron-Distal3.483374.75362K562PTBP1
chr6149998209149998318-intron-Distal3.237273.46531K562KHSRP
chr6149990621149990724-intron-Distal4.290004.24441HepG2ILF3
chr6150002585150002680-intron-Distal3.294803.64762HepG2QKI
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for LATS1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for LATS1 is not available on ENCORE database.

  • 69 RBPs can affect the levels of LATS1.  








The Knockdown/knockout RNA-Seq assay for LATS1 is not available on ENCORE database.





69 RBPs can affect the gene expression of LATS1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
LATS1ENSG00000131023.81202.59200968.040300.312902.357901.64410HepG2AKAP8L
LATS1ENSG00000131023.8614.49330885.00170-0.526302.190101.35940HepG2BCCIP
LATS1ENSG00000131023.8994.861901473.40490-0.566606.304405.44270HepG2BOP1
LATS1ENSG00000131023.81188.628801546.18340-0.379402.152901.30230HepG2CCAR1
LATS1ENSG00000131023.8547.03190845.81000-0.628704.977004.09450HepG2DDX21
LATS1ENSG00000131023.81907.929201471.313200.374802.744702.11960HepG2DDX3X
LATS1ENSG00000131023.82280.907701536.068800.570302.988101.97420HepG2DDX59
LATS1ENSG00000131023.8790.108101263.87630-0.677706.136705.24560HepG2DDX6
LATS1ENSG00000131023.8619.52690844.87780-0.447605.916905.01670HepG2DNAJC2
LATS1ENSG00000131023.8849.324501215.00700-0.516604.256203.52950HepG2EIF2S1
LATS1ENSG00000131023.81907.694901307.326400.545103.757902.96250HepG2EIF4B
LATS1ENSG00000131023.82512.477601631.616800.6227016.2579014.99960HepG2ETF1
LATS1ENSG00000131023.81110.82550745.613800.575006.423305.25380HepG2FUBP3
LATS1ENSG00000131023.81023.627801354.74210-0.404302.994802.27380HepG2FXR1
LATS1ENSG00000131023.81197.641501533.43530-0.356602.278601.69480HepG2GPKOW
LATS1ENSG00000131023.8721.55490985.11040-0.449202.328401.30540HepG2GRSF1
LATS1ENSG00000131023.8720.14450950.95640-0.401104.789804.01010HepG2HNRNPU
LATS1ENSG00000131023.8842.91240971.37460-0.204601.968701.33780HepG2ILF2
LATS1ENSG00000131023.8960.508401362.80280-0.504703.795003.06560HepG2MATR3
LATS1ENSG00000131023.82174.851801394.906800.640606.873205.89480HepG2NCBP2
LATS1ENSG00000131023.8877.589401164.71810-0.408404.551203.57370HepG2NOL12
LATS1ENSG00000131023.81770.326101297.523800.448203.905203.02080HepG2NSUN2
LATS1ENSG00000131023.8681.39800848.18130-0.315902.657801.93400HepG2PPIL4
LATS1ENSG00000131023.81146.55670941.842400.283702.348101.62870HepG2PRPF4
LATS1ENSG00000131023.8967.81560671.528600.527204.807903.77530HepG2PRPF8
LATS1ENSG00000131023.81653.824401180.184200.4867010.285809.29350HepG2PUM1
LATS1ENSG00000131023.81715.236301341.512900.354403.849303.12860HepG2QKI
LATS1ENSG00000131023.81937.927901102.105000.814205.620204.63690HepG2RAVER1
LATS1ENSG00000131023.81693.910901363.746500.312703.620603.04920HepG2RBM22
LATS1ENSG00000131023.81009.32070664.313500.603305.474704.40390HepG2RRP9
LATS1ENSG00000131023.82457.784001442.059400.769103.279102.54350HepG2SF3A3
LATS1ENSG00000131023.81330.440301065.965500.319604.054203.22810HepG2SLBP
LATS1ENSG00000131023.8736.13620987.63250-0.424005.928205.04230HepG2SMN1
LATS1ENSG00000131023.81963.231801540.331200.349905.931405.27470HepG2SRFBP1
LATS1ENSG00000131023.81037.750501346.05870-0.375304.888304.30540HepG2SRSF1
LATS1ENSG00000131023.82054.653601558.485200.398702.510101.56040HepG2SRSF3
LATS1ENSG00000131023.81345.011201097.693300.293003.044502.39120HepG2SRSF5
LATS1ENSG00000131023.81599.061701095.075800.5461010.918809.95020HepG2SRSF9
LATS1ENSG00000131023.81785.516701337.424000.416807.376806.61680HepG2SSB
LATS1ENSG00000131023.8944.595101426.18680-0.594406.570905.51800HepG2TARDBP
LATS1ENSG00000131023.8746.25860924.12230-0.308402.360801.89220HepG2TIAL1
LATS1ENSG00000131023.82310.813801127.349101.0354020.3683018.60860HepG2U2AF1
LATS1ENSG00000131023.8525.94690852.72210-0.697203.466902.66100HepG2XRN2
LATS1ENSG00000131023.81372.66940929.479600.5624011.3602010.15640HepG2ZC3H8
LATS1ENSG00000131023.81674.932801406.530800.251903.448302.85680HepG2ZNF622
LATS1ENSG00000131023.81776.131302300.79300-0.373406.237505.43820K562AGGF1
LATS1ENSG00000131023.83997.295302666.020300.584208.094607.17870K562AQR
LATS1ENSG00000131023.82125.232902511.89190-0.241202.584701.70390K562ATP5C1
LATS1ENSG00000131023.81270.588601504.43740-0.243702.484801.57810K562BCLAF1
LATS1ENSG00000131023.82079.354202499.42000-0.265502.517101.76800K562CPSF6
LATS1ENSG00000131023.8926.293201141.33990-0.301202.528801.52410K562CSTF2
LATS1ENSG00000131023.81293.505401555.99500-0.266602.742001.54160K562EIF2S1
LATS1ENSG00000131023.82452.743402104.040600.221102.389601.71310K562EIF2S2
LATS1ENSG00000131023.81901.883601479.913400.361803.378802.47490K562EIF4A3
LATS1ENSG00000131023.81544.138802795.26970-0.856209.047207.41870K562FIP1L1
LATS1ENSG00000131023.81969.552501539.055100.355704.956904.18080K562FXR1
LATS1ENSG00000131023.82090.685601464.307100.513703.727702.88010K562G3BP2
LATS1ENSG00000131023.81749.164802386.34840-0.448105.183404.10290K562GPKOW
LATS1ENSG00000131023.81358.416402803.98420-1.0456025.4512023.05860K562GRSF1
LATS1ENSG00000131023.81722.256002298.99660-0.416703.356902.32410K562HNRNPM
LATS1ENSG00000131023.82535.305703790.00630-0.580005.353304.26340K562HSPD1
LATS1ENSG00000131023.81550.412502329.33500-0.587308.301206.73620K562METAP2
LATS1ENSG00000131023.81656.466602149.14730-0.375706.275305.09940K562MTPAP
LATS1ENSG00000131023.82098.251102387.97000-0.186602.772802.02570K562NSUN2
LATS1ENSG00000131023.81077.172801455.11730-0.433902.818101.38190K562NUSAP1
LATS1ENSG00000131023.82388.246701762.919000.437904.875603.56670K562PCBP2
LATS1ENSG00000131023.81901.420003172.96390-0.738808.467506.83940K562PPIG
LATS1ENSG00000131023.82084.664501443.981000.529706.003204.89730K562PRPF8
LATS1ENSG00000131023.8985.424901325.25800-0.427503.877402.77860K562PSIP1
LATS1ENSG00000131023.81076.653401441.62930-0.421103.066201.34320K562SRP68
LATS1ENSG00000131023.81251.214701886.81120-0.592605.982604.95200K562SRSF1
LATS1ENSG00000131023.82197.457501791.038300.294902.649501.84850K562SYNCRIP
LATS1ENSG00000131023.81488.509401909.79500-0.359502.572601.88840K562TARDBP
LATS1ENSG00000131023.81393.632801807.18390-0.374903.394402.15870K562TRA2A
LATS1ENSG00000131023.81978.041201419.785200.478303.981502.62010K562U2AF1
LATS1ENSG00000131023.82030.016201466.199600.469306.512005.28550K562U2AF2
LATS1ENSG00000131023.82022.053902532.00930-0.324505.560604.58270K562UPF1
LATS1ENSG00000131023.81801.737802166.57000-0.266002.285001.48830K562WDR3
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for LATS1 is not available on ENCORE database.





10 RBPs can affect the splicing of LATS1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SELATS1ENSG00000131023.8chr6-1499998171499998811499976901499978731500010101500015930.146000.000090.00287includedK562SRSF1
SELATS1ENSG00000131023.8chr6-1500182271500183221500162091500163571500229141500234020.181000.000030.00246includedK562PRPF8
SELATS1ENSG00000131023.8chr6-1499998171499998811499976901499978731500010101500015930.057000.000070.02939includedK562PUM1
SELATS1ENSG00000131023.8chr6-1499998171499998811499976901499978731500010101500015930.107000.000640.00964includedHepG2U2AF2
SELATS1ENSG00000131023.8chr6-149999817149999881149997690149997873150001010150001593-0.079000.000250.04497excludedK562DROSHA
SELATS1ENSG00000131023.8chr6-149997395149997502149982229149983374149997690149997873-0.116000.000660.01207excludedK562PUS1
SELATS1ENSG00000131023.8chr6-1500182271500183221500162091500163571500229141500234020.121000.001990.08395includedK562EFTUD2
SELATS1ENSG00000131023.8chr6-1500182271500183221500162091500163571500229141500234020.482000.001410.08528includedHepG2HNRNPL
SELATS1ENSG00000131023.8chr6-1500182271500183221500162091500163571500229141500234020.152000.000550.04154includedK562HNRNPL
SELATS1ENSG00000131023.8chr6-1499998171499998811499976901499978731500010101500015930.070000.000010.00523includedK562EIF4G2
A3SSLATS1ENSG00000131023.8chr6-1500055391500057771500055391500057281500162091500163570.065000.007090.03927longerK562AQR
A3SSLATS1ENSG00000131023.8chr6-1500162091500164391500162091500163571500229141500230990.067000.007990.04357longerK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for LATS1 is not avaliable on ENCORE database.