L3MBTL2

General Information

Gene Name       : L3MBTL2
Gene ID             : ENSG00000100395.14
Essential Gene : No

Functions

Localization

Domains (AlphaFold: L3MBTL2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878L3MBTL2ENSG00000100395.1414.6518.7416.70ENCSR000AEF
HepG2L3MBTL2ENSG00000100395.1421.0917.2119.15ENCSR985KAT
K562L3MBTL2ENSG00000100395.1414.9115.4815.20ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for L3MBTL2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • L3MBTL2 RNA is bound by 6 proteins.  







eCLIP assay for L3MBTL2 is not avaliable on ENCORE database.





6 proteins are bound to L3MBTL2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr224160569941605857+3'-UTR,CDS,intron-Proximal3.194723.85127HepG2GRWD1
chr224162371041623828+3'-UTR,CDS,intron-Proximal5.878227.02785HepG2SF3A3
chr224160570541605761+3'-UTR,CDS4.217413.49905HepG2PPIG
chr224160577041605889+3'-UTR,CDS4.261623.45943HepG2BCLAF1
chr224161547141615529+CDS,intron-Distal4.430964.08604HepG2PPIG
chr224162194441622024+CDS,intron-Proximal4.392347.15298K562AQR
chr224161350541613599+intron-Distal4.902825.13577HepG2U2AF2
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for L3MBTL2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for L3MBTL2 is not available on ENCORE database.

  • 80 RBPs can affect the levels of L3MBTL2.  








The Knockdown/knockout RNA-Seq assay for L3MBTL2 is not available on ENCORE database.





80 RBPs can affect the gene expression of L3MBTL2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
L3MBTL2ENSG00000100395.10879.21300588.734400.578504.673403.47670HepG2ABCF1
L3MBTL2ENSG00000100395.10657.32560546.566600.266101.984101.45310HepG2ACO1
L3MBTL2ENSG00000100395.101544.00160506.115001.6090028.0553026.57310HepG2AKAP1
L3MBTL2ENSG00000100395.10805.86270397.858401.0182012.1292010.62650HepG2CIRBP
L3MBTL2ENSG00000100395.10409.50360288.425800.505601.973101.33220HepG2CNOT7
L3MBTL2ENSG00000100395.10333.93020567.11320-0.764106.246205.24350HepG2CPSF6
L3MBTL2ENSG00000100395.10688.28700383.650900.843109.241808.07790HepG2DDX21
L3MBTL2ENSG00000100395.101034.78930484.820801.0937014.3985013.08460HepG2DDX3X
L3MBTL2ENSG00000100395.10441.65230643.99710-0.544102.169401.30750HepG2DDX59
L3MBTL2ENSG00000100395.10668.26350522.907300.353802.800902.11970HepG2DKC1
L3MBTL2ENSG00000100395.10256.28730407.02430-0.667405.607504.63640HepG2DNAJC21
L3MBTL2ENSG00000100395.10607.15330374.604100.696605.288204.04870HepG2EEF2
L3MBTL2ENSG00000100395.10424.92020312.275700.444302.315701.30310HepG2EFTUD2
L3MBTL2ENSG00000100395.10526.71790362.249700.539904.162802.86910HepG2EIF3G
L3MBTL2ENSG00000100395.101129.60570442.450001.3521019.9018018.20940HepG2EIF4A3
L3MBTL2ENSG00000100395.10769.86950430.785400.837506.194405.19500HepG2EIF4B
L3MBTL2ENSG00000100395.10503.12130675.91500-0.425902.762101.94780HepG2EIF4G2
L3MBTL2ENSG00000100395.10732.61210534.063100.455903.723002.75450HepG2EWSR1
L3MBTL2ENSG00000100395.10840.51300446.410600.912809.991408.75160HepG2FXR1
L3MBTL2ENSG00000100395.10754.21690414.112800.864908.455707.32630HepG2G3BP1
L3MBTL2ENSG00000100395.10619.27380439.631900.494203.170002.21490HepG2G3BP2
L3MBTL2ENSG00000100395.10413.32920270.748100.610203.744702.68790HepG2GEMIN5
L3MBTL2ENSG00000100395.10550.83900410.923900.422702.563901.93950HepG2HNRNPA1
L3MBTL2ENSG00000100395.10650.26730457.084500.508503.661302.87260HepG2HNRNPC
L3MBTL2ENSG00000100395.10636.36420780.90310-0.295302.321001.66010HepG2HNRNPF
L3MBTL2ENSG00000100395.10354.62450613.51150-0.790806.874505.93290HepG2HNRNPLL
L3MBTL2ENSG00000100395.10573.51210410.324900.483003.900702.79040HepG2HNRNPM
L3MBTL2ENSG00000100395.10707.59300420.937200.749206.710805.70160HepG2IGF2BP2
L3MBTL2ENSG00000100395.10947.83600603.839400.650404.776803.67430HepG2LARP4
L3MBTL2ENSG00000100395.10916.75420446.566501.0376012.6645011.29960HepG2MAGOH
L3MBTL2ENSG00000100395.10990.67780449.066301.1414013.9305012.59320HepG2MATR3
L3MBTL2ENSG00000100395.10640.45450481.372800.411803.138502.28000HepG2MSI2
L3MBTL2ENSG00000100395.10441.41350625.67240-0.503302.172801.32240HepG2MTPAP
L3MBTL2ENSG00000100395.101037.72180459.644701.1747015.9509014.51420HepG2NCBP2
L3MBTL2ENSG00000100395.10284.33160543.98550-0.936008.677107.40400HepG2NSUN2
L3MBTL2ENSG00000100395.10637.00050442.006900.527105.346404.54730HepG2PCBP1
L3MBTL2ENSG00000100395.10303.89580404.98570-0.414302.654901.93140HepG2PPIL4
L3MBTL2ENSG00000100395.10667.89880449.736800.570406.251705.49410HepG2PTBP1
L3MBTL2ENSG00000100395.101004.03900718.655100.482307.737306.84950HepG2PUM1
L3MBTL2ENSG00000100395.10407.56650718.12700-0.8172010.221808.97570HepG2PUM2
L3MBTL2ENSG00000100395.10781.03790556.708500.488406.005105.16000HepG2PUS1
L3MBTL2ENSG00000100395.10690.07210487.122400.502404.316903.56200HepG2QKI
L3MBTL2ENSG00000100395.10885.60760500.532000.8231012.8846011.87600HepG2NELFE
L3MBTL2ENSG00000100395.10622.30130466.144800.416703.350602.68000HepG2RECQL
L3MBTL2ENSG00000100395.10499.08650295.899000.754106.654205.74720HepG2RPS19
L3MBTL2ENSG00000100395.10220.39650489.31450-1.1507010.146308.77970HepG2RRP9
L3MBTL2ENSG00000100395.10296.52100475.57400-0.681503.510201.78510HepG2RTF1
L3MBTL2ENSG00000100395.10305.11650404.35780-0.406302.736502.09430HepG2SAFB2
L3MBTL2ENSG00000100395.10419.68380296.967000.498902.757901.82020HepG2SERBP1
L3MBTL2ENSG00000100395.101154.00970555.249801.0553011.433209.99770HepG2SF3A3
L3MBTL2ENSG00000100395.10441.85940607.26300-0.458702.982302.25000HepG2SF3B1
L3MBTL2ENSG00000100395.10677.58690468.273100.533005.314504.54040HepG2SF3B4
L3MBTL2ENSG00000100395.10499.98860649.13400-0.376603.381102.61850HepG2SLBP
L3MBTL2ENSG00000100395.10674.80320471.541900.517006.298705.39100HepG2SMN1
L3MBTL2ENSG00000100395.10611.75140446.176600.455202.342801.46990HepG2SMNDC1
L3MBTL2ENSG00000100395.101059.01090488.759801.1154025.9529024.82550HepG2SRSF1
L3MBTL2ENSG00000100395.101000.39700668.430600.581608.884807.84700HepG2SRSF5
L3MBTL2ENSG00000100395.10550.14020767.19810-0.479805.348304.43360HepG2SRSF7
L3MBTL2ENSG00000100395.101017.72550760.184600.420805.588704.76190HepG2SUCLG1
L3MBTL2ENSG00000100395.10414.43690638.30870-0.623103.987003.19740HepG2SUPV3L1
L3MBTL2ENSG00000100395.10323.50190439.27220-0.441303.081902.49460HepG2TAF15
L3MBTL2ENSG00000100395.10706.93890417.598200.759403.232502.08100HepG2TBRG4
L3MBTL2ENSG00000100395.10688.76880441.177400.642606.957406.23040HepG2TIAL1
L3MBTL2ENSG00000100395.10266.74550445.15200-0.738808.004307.12390HepG2TRIM56
L3MBTL2ENSG00000100395.10681.74970492.422100.469204.988104.09300HepG2UPF1
L3MBTL2ENSG00000100395.10641.27010475.413600.431603.917803.22350HepG2UTP3
L3MBTL2ENSG00000100395.10839.76370541.569500.6327010.588509.69180HepG2ZNF622
L3MBTL2ENSG00000100395.10365.17470488.85040-0.420802.887102.30850K562AGGF1
L3MBTL2ENSG00000100395.101328.54020985.208700.431203.656102.20670K562APOBEC3C
L3MBTL2ENSG00000100395.10988.33880806.273600.293602.666902.02500K562DDX47
L3MBTL2ENSG00000100395.10554.95570387.031300.519802.191901.30920K562EIF3A
L3MBTL2ENSG00000100395.10579.16100339.733300.769508.901807.47630K562EIF3G
L3MBTL2ENSG00000100395.10565.68320342.572200.723506.658305.39560K562EIF4A3
L3MBTL2ENSG00000100395.10248.28590363.45580-0.549803.084901.38830K562FASTKD2
L3MBTL2ENSG00000100395.10278.50810430.18180-0.627203.876002.51430K562FKBP4
L3MBTL2ENSG00000100395.10818.71010356.258301.2003023.9453022.28230K562FXR1
L3MBTL2ENSG00000100395.10127.93220238.48520-0.898504.548103.59260K562G3BP2
L3MBTL2ENSG00000100395.10889.861501266.05420-0.508705.263604.21600K562GRSF1
L3MBTL2ENSG00000100395.10629.68590495.658300.345202.126501.59480K562HNRNPC
L3MBTL2ENSG00000100395.10803.20950566.939100.502503.420502.37680K562HNRNPM
L3MBTL2ENSG00000100395.10513.72940746.68040-0.539505.775604.47130K562HNRNPU
L3MBTL2ENSG00000100395.10570.46470364.586900.645806.045104.78590K562MAGOH
L3MBTL2ENSG00000100395.10485.13600363.808200.415102.685101.77750K562MATR3
L3MBTL2ENSG00000100395.10561.14200707.51420-0.334403.196402.39880K562NSUN2
L3MBTL2ENSG00000100395.10712.54030538.970200.402702.529701.81230K562PRPF8
L3MBTL2ENSG00000100395.10479.10360354.238100.435502.968202.28260K562PTBP1
L3MBTL2ENSG00000100395.10897.706201269.59020-0.500002.394901.50070K562PUM2
L3MBTL2ENSG00000100395.10489.37500339.531900.527303.693602.71090K562RBM22
L3MBTL2ENSG00000100395.10480.93210357.335800.428502.444601.42860K562NELFE
L3MBTL2ENSG00000100395.10811.12510559.264000.536304.904103.46390K562SAFB
L3MBTL2ENSG00000100395.10351.56440248.085700.502903.277002.34500K562SF3B4
L3MBTL2ENSG00000100395.10757.71250347.300301.1254016.7485015.01650K562SRSF1
L3MBTL2ENSG00000100395.10534.97050661.57270-0.306402.459701.36030K562SRSF7
L3MBTL2ENSG00000100395.101100.92890629.558100.8062012.9817011.20530K562SYNCRIP
L3MBTL2ENSG00000100395.10580.60370351.428500.724205.724004.68450K562TARDBP
L3MBTL2ENSG00000100395.10314.70040454.04400-0.528903.371702.30800K562TRIM56
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for L3MBTL2 is not available on ENCORE database.





9 RBPs can affect the splicing of L3MBTL2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEL3MBTL2ENSG00000100395.10chr22+416235224162368341623092416233274162380741623873-0.110000.000580.04899excludedHepG2TBRG4
SEL3MBTL2ENSG00000100395.10chr22+416235784162368341623092416233274162380741623873-0.097000.002670.08728excludedHepG2MATR3
SEL3MBTL2ENSG00000100395.10chr22+416235784162368341623092416233274162380741623873-0.157000.003560.05318excludedK562HNRNPC
A3SSL3MBTL2ENSG00000100395.10chr22+4162094141621075416209704162107541620728416208050.067000.000890.00624longerK562AQR
A5SSL3MBTL2ENSG00000100395.10chr22+4162554341625758416255434162566041626142416272750.125000.000030.00087longerK562AQR
A5SSL3MBTL2ENSG00000100395.10chr22+4162259241622811416225924162274841623092416233270.086000.001440.02563longerK562AQR
RIL3MBTL2ENSG00000100395.10chr22+416230924162387341623092416233274162380741623873-0.301000.000370.01162excludedK562HNRNPC
RIL3MBTL2ENSG00000100395.10chr22+416230924162387341623092416233274162380741623873-0.286000.000180.00644excludedK562SRSF1
RIL3MBTL2ENSG00000100395.10chr22+416230924162387341623092416233274162380741623873-0.259000.001130.09761excludedK562MATR3
RIL3MBTL2ENSG00000100395.10chr22+4162309241623873416230924162332741623807416238730.185000.002190.09433includedHepG2SUPV3L1
RIL3MBTL2ENSG00000100395.10chr22+4161312641615540416131264161320641615422416155400.211000.009720.08197includedK562RBM15
RIL3MBTL2ENSG00000100395.10chr22+4162309241623873416230924162332741623807416238730.353000.000010.00035includedHepG2HNRNPK
RIL3MBTL2ENSG00000100395.10chr22+4161312641615540416131264161320641615422416155400.113000.000620.00438includedK562AQR
RIL3MBTL2ENSG00000100395.10chr22+4162309241623873416230924162332741623807416238730.118000.006660.03735includedK562AQR
RIL3MBTL2ENSG00000100395.10chr22+416230924162387341623092416233274162380741623873-0.272000.000440.02034excludedK562TARDBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for L3MBTL2 is not avaliable on ENCORE database.