HOOK3

General Information

Gene Name       : HOOK3
Gene ID             : ENSG00000168172.8
Essential Gene : No

Functions

Localization

Domains (AlphaFold: HOOK3)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878HOOK3ENSG00000168172.84.745.555.14ENCSR000AEF
HepG2HOOK3ENSG00000168172.86.8615.6911.28ENCSR985KAT
K562HOOK3ENSG00000168172.85.327.986.65ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for HOOK3 is not avaliable on ENCORE database.



Proteins bound to RNA
  • HOOK3 RNA is bound by 35 proteins.  







eCLIP assay for HOOK3 is not avaliable on ENCORE database.





35 proteins are bound to HOOK3 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr84287406142874133+3'-UTR,intron-Distal3.992463.92684K562KHSRP
chr84287858642878651+3'-UTR,intron-Distal3.8862112.40547K562PCBP1
chr84285274142852791+3'-UTR,CDS,intron-Proximal3.574493.73423K562UCHL5
chr84287384442873956+3'-UTR,intron-Distal3.300109.74899K562PUM2
chr84287859842878675+3'-UTR,intron-Distal5.3228917.91501HepG2PCBP2
chr84287459742874685+3'-UTR,intron-Distal5.1348126.37577K562QKI
chr84286302842863072+3'-UTR,CDS3.047403.50663K562ZNF800
chr84287891242878957+3'-UTR,intron-Distal3.468223.61097K562ILF3
chr84287855342878674+3'-UTR,intron-Distal4.4321324.88137K562U2AF2
chr84288151342881578+3'-UTR,intron-Distal4.466895.66560K562TIA1
chr84287556442875639+3'-UTR,intron-Distal3.848883.71997HepG2ILF3
chr84287462942874695+3'-UTR,intron-Distal5.4002918.83782HepG2QKI
chr84286544442865518+3'-UTR,CDS,intron-Proximal4.7184010.13662HepG2BCLAF1
chr84288334742883420+3'-UTR,intron-Distal3.586809.76503K562FAM120A
chr84288516742885260+3'-UTR,intron-Distal4.189714.43679K562IGF2BP1
chr84287350042873576+3'-UTR,CDS,intron-Proximal3.715666.39464HepG2BCLAF1
chr84288176042881920+3'-UTR,intron-Distal3.510014.81657K562IGF2BP1
chr84287858842878664+3'-UTR,intron-Distal5.4923158.59353K562PTBP1
chr84285271942852795+3'-UTR,CDS,intron-Proximal3.824315.80935K562ZNF622
chr84287390142873964+3'-UTR,intron-Distal4.398856.93714HepG2FUBP3
chr84285725742857285+3'-UTR,CDS,intron-Proximal4.636094.34038HepG2BCLAF1
chr84286304042863075+3'-UTR,CDS,intron-Proximal3.372823.28366HepG2BCLAF1
chr84287354842873669+3'-UTR,CDS,intron-Proximal3.198834.24070HepG2GRWD1
chr84288523742885287+3'-UTR,intron-Distal4.606878.61496K562PUM2
chr84287404442874119+3'-UTR,intron-Distal4.148933.20552HepG2KHSRP
chr84288363242883704+3'-UTR,intron-Distal4.8892112.02341K562FAM120A
chr84287858842878683+3'-UTR,intron-Distal4.371287.97328HepG2PCBP1
chr84287382342873901+3'-UTR,intron-Distal3.606047.17745HepG2FUBP3
chr84286544042865556+3'-UTR,CDS,intron-Proximal4.217234.10495HepG2AGGF1
chr84287854442878669+3'-UTR,intron-Distal4.523043.02097K562U2AF1
chr84287858842878669+3'-UTR,intron-Distal5.7773571.38312HepG2PTBP1
chr84287459042874629+3'-UTR,intron-Distal5.7385612.21592HepG2QKI
chr84285274742852783+3'-UTR,CDS,intron-Proximal3.583553.57857HepG2BCLAF1
chr84287910842879215+3'-UTR,intron-Distal3.232365.64172K562FAM120A
chr84287407442874128+3'-UTR,intron-Distal5.128577.24158HepG2FUBP3
chr84287858342878666+3'-UTR,intron-Distal5.4421424.07042HepG2U2AF2
chr84287860142878666+3'-UTR,intron-Distal3.865803.17235HepG2HNRNPK
chr84285269542852734+3'-UTR,CDS4.319363.71570HepG2BCLAF1
chr84275209442752174+5'-UTR3.111823.21309HepG2GRWD1
chr84275217042752276+5'-UTR,CDS3.165066.72797HepG2DDX3X
chr84275227042752328+5'-UTR,CDS3.852674.66602K562DDX3X
chr84275209642752206+5'-UTR3.575907.42472HepG2NCBP2
chr84275209842752264+5'-UTR3.191703.74019K562DDX3X
chr84286851442868545+CDS,intron-Proximal3.406383.68471HepG2BCLAF1
chr84281955142819618+CDS,intron-Proximal3.149877.17439HepG2BCLAF1
chr84284179742841857+CDS,intron-Proximal3.763856.36847HepG2BCLAF1
chr84282160942821768+CDS,intron-Proximal4.3347810.41018HepG2GRWD1
chr84282161442821642+CDS,intron-Proximal3.059624.30396K562UCHL5
chr84282162242821729+CDS3.541145.66840K562ZNF622
chr84281953042819618+CDS,intron-Proximal3.588169.11524K562UCHL5
chr84286819242868256+CDS,intron-Proximal4.6250815.10546HepG2BCLAF1
chr84278071542780773+CDS,intron-Proximal3.051133.17233HepG2BCLAF1
chr84284179342841903+CDS,intron-Proximal4.119916.81238K562ZNF622
chr84282164242821697+CDS3.548264.49347K562UCHL5
chr84286825642868298+CDS3.215664.26492HepG2BCLAF1
chr84279845942798614+CDS,intron-Proximal3.874734.48684HepG2ZNF800
chr84284179642841868+CDS,intron-Proximal3.324885.12958K562UCHL5
chr84284179642841887+CDS,intron-Proximal4.165284.23295HepG2GRWD1
chr84283776942837840+CDS,intron-Proximal3.452705.65306K562ZNF622
chr84286819142868297+CDS,intron-Proximal3.910585.09222HepG2FXR2
chr84282924442829294+CDS,intron-Proximal4.012846.81238K562ZNF622
chr84282161442821681+CDS,intron-Proximal4.325005.70529K562GRWD1
chr84282929142829341+CDS,intron-Proximal4.7813910.80414HepG2BCLAF1
chr84278528842785315+CDS4.291073.89826HepG2BCLAF1
chr84282924842829292+CDS,intron-Proximal3.617364.40383K562UCHL5
chr84282847842828541+CDS4.471028.41475HepG2BCLAF1
chr84283777142837817+CDS4.357093.01428K562UCHL5
chr84282924642829291+CDS,intron-Proximal4.042898.49795HepG2BCLAF1
chr84282161542821710+CDS,intron-Proximal3.118704.56572K562ZNF800
chr84281437642814463+CDS,intron-Proximal3.699866.46787HepG2GRWD1
chr84282929242829338+CDS,intron-Proximal4.570804.07072K562UCHL5
chr84281954942819620+CDS,intron-Proximal4.281183.82843HepG2PPIG
chr84276131242761402+CDS,intron-Proximal3.573845.14253HepG2GRWD1
chr84281944642819502+CDS,intron-Proximal4.419604.50440HepG2PPIG
chr84282929442829338+CDS,intron-Proximal3.478373.07653K562ZNF622
chr84279845442798590+CDS,intron-Proximal4.9063819.15489HepG2BCLAF1
chr84286551842865550+CDS,intron-Proximal4.805355.37137HepG2BCLAF1
chr84282850442828542+CDS3.603134.20387K562ZNF622
chr84285535142855426+CDS,intron-Distal,intron-Proximal4.406004.05848HepG2QKI
chr84283776942837840+CDS,intron-Proximal4.173529.69111HepG2BCLAF1
chr84284179442841904+CDS,intron-Proximal4.088683.96990K562BUD13
chr84275231342752392+CDS,intron-Proximal4.409655.60609HepG2CSTF2T
chr84279845542798587+CDS,intron-Proximal3.102267.66025K562ZNF622
chr84282161342821731+CDS,intron-Proximal3.9736411.95754HepG2BCLAF1
chr84282169742821757+CDS,intron-Proximal4.294784.42734K562UCHL5
chr84279845542798571+CDS,intron-Proximal3.092865.55505K562DDX24
chr84277037342770458+intron-Distal4.319535.18400HepG2ILF3
chr84277058742770635+intron-Distal4.009843.77875HepG2ILF3
chr84280292842803048+intron-Distal4.190638.23610K562TARDBP
chr84278687342786925+intron-Distal4.625104.97123HepG2PCBP2
chr84275274342752844+intron-Distal4.533735.81141K562CSTF2T
chr84275276442752805+intron-Distal3.387513.41711K562DROSHA
chr84275307742753135+intron-Distal3.054053.25653K562CSTF2T
chr84279126242791343+intron-Distal5.030677.06230K562EXOSC5
chr84275238642752441+intron-Distal,intron-Proximal4.126924.61506HepG2EFTUD2
chr84285096142851134+intron-Distal4.071993.23532K562MATR3
chr84280364242803767+intron-Distal7.0639928.17729HepG2QKI
chr84275306142753147+intron-Distal4.400134.23759K562NONO
chr84282176442821929+intron-Distal,intron-Proximal4.234654.21433K562PRPF8
chr84276687842766947+intron-Distal3.629993.01412K562SAFB2
chr84285091142851016+intron-Distal4.311144.74221HepG2PTBP1
chr84279250642792552+intron-Distal5.147667.38693K562EXOSC5
chr84276141242761514+intron-Distal,intron-Proximal4.538785.41654K562KHSRP
chr84280362042803736+intron-Distal6.5554815.08232K562QKI
chr84275244142752483+intron-Distal5.126925.96317HepG2EFTUD2
chr84285091042851026+intron-Distal4.483373.42734K562PTBP1
chr84275273742752850+intron-Distal4.886896.64417K562NONO
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for HOOK3 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for HOOK3 is not available on ENCORE database.

  • 91 RBPs can affect the levels of HOOK3.  








The Knockdown/knockout RNA-Seq assay for HOOK3 is not available on ENCORE database.





91 RBPs can affect the gene expression of HOOK3 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
HOOK3ENSG00000168172.4895.334601199.11800-0.421503.353702.26300HepG2ADAR
HOOK3ENSG00000168172.41462.091602034.10200-0.476403.106502.54710HepG2AKAP1
HOOK3ENSG00000168172.41254.323601683.09980-0.424203.173602.33180HepG2ASCC1
HOOK3ENSG00000168172.4585.697801281.55600-1.1297013.7280011.54610HepG2BCCIP
HOOK3ENSG00000168172.41529.310601212.128600.335203.279802.44800HepG2CALR
HOOK3ENSG00000168172.41103.943001599.04420-0.534504.974003.95290HepG2CIRBP
HOOK3ENSG00000168172.41104.914501590.82640-0.5258011.4697010.30380HepG2CKAP4
HOOK3ENSG00000168172.4934.121201229.66550-0.396604.641403.32560HepG2YBX3
HOOK3ENSG00000168172.41427.830101030.259600.470702.872701.48120HepG2CSTF2T
HOOK3ENSG00000168172.41341.311501550.27950-0.208902.017001.45190HepG2CELF1
HOOK3ENSG00000168172.41472.339801667.16660-0.179302.192501.52120HepG2DAZAP1
HOOK3ENSG00000168172.41267.928201471.56020-0.214902.404501.62150HepG2DDX19B
HOOK3ENSG00000168172.41459.588001948.62570-0.416902.903002.26410HepG2DDX3X
HOOK3ENSG00000168172.4957.957001259.98110-0.395402.025401.35330HepG2DDX55
HOOK3ENSG00000168172.4910.409201207.47870-0.407404.865203.95620HepG2DNAJC21
HOOK3ENSG00000168172.4782.291001196.75920-0.6134012.9841011.68090HepG2DNAJC2
HOOK3ENSG00000168172.4941.46570723.474200.379902.973802.16120HepG2FUBP3
HOOK3ENSG00000168172.41854.946401311.614300.499904.287103.50190HepG2GPKOW
HOOK3ENSG00000168172.41068.478001643.01380-0.620803.374902.14100HepG2GRSF1
HOOK3ENSG00000168172.4974.968001219.04600-0.322302.432501.82430HepG2HNRNPA1
HOOK3ENSG00000168172.41068.097001355.94440-0.344302.717202.02960HepG2HNRNPC
HOOK3ENSG00000168172.41339.516601684.90000-0.331002.475101.81210HepG2HNRNPK
HOOK3ENSG00000168172.41293.338501518.73260-0.231802.507901.86330HepG2HNRNPL
HOOK3ENSG00000168172.41787.759301251.691200.514205.126804.29710HepG2HNRNPLL
HOOK3ENSG00000168172.4825.769401044.60390-0.339102.617501.69070HepG2HNRNPM
HOOK3ENSG00000168172.41036.250701346.98110-0.378405.173504.36450HepG2HNRNPU
HOOK3ENSG00000168172.41046.374201375.89980-0.395006.396905.32710HepG2ILF2
HOOK3ENSG00000168172.41147.663701454.50200-0.341805.234503.83980HepG2KIF1C
HOOK3ENSG00000168172.41446.690502033.79400-0.491403.292602.38460HepG2LARP4
HOOK3ENSG00000168172.41478.094201847.30250-0.321702.062501.51160HepG2NCBP2
HOOK3ENSG00000168172.41004.313301333.30430-0.408805.582404.43750HepG2PARN
HOOK3ENSG00000168172.4797.060201201.40280-0.592009.135307.84290HepG2PPIL4
HOOK3ENSG00000168172.41115.424701486.48080-0.414305.845705.11000HepG2PTBP1
HOOK3ENSG00000168172.41282.710301675.04800-0.385007.680006.79440HepG2PUM1
HOOK3ENSG00000168172.4743.178701620.62570-1.1248041.0315039.21770HepG2PUS1
HOOK3ENSG00000168172.42223.686401461.106300.605807.510906.44540HepG2RBM25
HOOK3ENSG00000168172.4792.605801224.29810-0.627302.531301.51770HepG2RCC2
HOOK3ENSG00000168172.41312.622101781.26370-0.440402.345601.60620HepG2RPS3A
HOOK3ENSG00000168172.4832.335501199.55740-0.527309.141108.07780HepG2SAFB2
HOOK3ENSG00000168172.4879.897101398.90540-0.6689016.9949015.60560HepG2SMN1
HOOK3ENSG00000168172.42335.264701615.401500.531609.988509.21480HepG2SRSF1
HOOK3ENSG00000168172.41518.487001314.202500.208302.057301.56660HepG2SRSF9
HOOK3ENSG00000168172.41032.681101549.08020-0.585003.674202.38910HepG2STIP1
HOOK3ENSG00000168172.41572.764501771.90920-0.172001.962801.42220HepG2SUCLG1
HOOK3ENSG00000168172.41619.367601254.377900.368402.779202.10120HepG2SUPV3L1
HOOK3ENSG00000168172.41904.772801334.183000.513604.402603.35620HepG2TIA1
HOOK3ENSG00000168172.4992.810101308.91480-0.398804.342303.74480HepG2TIAL1
HOOK3ENSG00000168172.4684.053101320.53930-0.9489025.5795024.08260HepG2TRIM56
HOOK3ENSG00000168172.41599.062301295.132100.304002.066901.51520HepG2U2AF1
HOOK3ENSG00000168172.4349.86110741.05850-1.0828012.8883011.27880HepG2UCHL5
HOOK3ENSG00000168172.41312.061101555.89490-0.245902.745202.15030HepG2UTP3
HOOK3ENSG00000168172.4530.685401234.79490-1.2183018.1117016.30620HepG2XRN2
HOOK3ENSG00000168172.41518.681901845.76860-0.281403.499202.87380K562AGGF1
HOOK3ENSG00000168172.41103.085801395.38300-0.339103.847102.03630K562AKAP1
HOOK3ENSG00000168172.41385.842101920.58630-0.470805.218604.30900K562AKAP8L
HOOK3ENSG00000168172.41372.419901828.77720-0.414203.721003.06050K562AQR
HOOK3ENSG00000168172.41559.529102015.12030-0.369804.890603.63830K562ATP5C1
HOOK3ENSG00000168172.41830.276602205.85840-0.269302.594801.46410K562CCDC124
HOOK3ENSG00000168172.41557.863702004.93720-0.364003.245801.84250K562CIRBP
HOOK3ENSG00000168172.4711.88200887.69220-0.318402.548301.54060K562CSTF2
HOOK3ENSG00000168172.41049.372901262.40600-0.266602.530001.37390K562DDX21
HOOK3ENSG00000168172.41132.162401433.53090-0.340503.672202.11020K562DDX6
HOOK3ENSG00000168172.4625.898101140.33590-0.8655011.203009.22950K562EFTUD2
HOOK3ENSG00000168172.4949.645701275.42800-0.425505.336304.38520K562EIF2S2
HOOK3ENSG00000168172.41034.883401259.01070-0.282802.592201.81990K562EIF3G
HOOK3ENSG00000168172.41193.043501477.20670-0.308202.078201.36240K562EIF4A3
HOOK3ENSG00000168172.4824.804301306.19960-0.663308.104006.57190K562FIP1L1
HOOK3ENSG00000168172.41289.137001536.23570-0.253002.392801.82250K562FXR1
HOOK3ENSG00000168172.41923.262201514.817400.344301.941101.36080K562G3BP2
HOOK3ENSG00000168172.4859.772001699.71290-0.9833019.0708017.00630K562GRSF1
HOOK3ENSG00000168172.4480.192001019.19640-1.0857018.3417016.88660K562HNRNPC
HOOK3ENSG00000168172.4680.37300910.10480-0.419703.383802.11440K562HNRNPF
HOOK3ENSG00000168172.41379.624401836.70760-0.412804.458203.07980K562HNRNPL
HOOK3ENSG00000168172.4508.842101074.38190-1.0782013.9667011.46510K562HNRNPM
HOOK3ENSG00000168172.41163.857101770.90950-0.605607.380306.09670K562HSPD1
HOOK3ENSG00000168172.41449.529501869.94160-0.367402.315301.40030K562IGF2BP2
HOOK3ENSG00000168172.41718.513402038.29080-0.246202.175401.45480K562KIF1C
HOOK3ENSG00000168172.41553.165701965.99910-0.340102.430901.63980K562MAGOH
HOOK3ENSG00000168172.41480.618201962.12680-0.406204.216703.05870K562MATR3
HOOK3ENSG00000168172.41053.735401420.27890-0.430706.522705.32910K562MTPAP
HOOK3ENSG00000168172.4724.063301123.43220-0.633705.955203.90070K562NONO
HOOK3ENSG00000168172.4673.686501003.43650-0.574804.970102.83240K562NUSAP1
HOOK3ENSG00000168172.4682.09810995.02220-0.544704.020102.24940K562PHF6
HOOK3ENSG00000168172.4807.480401482.81520-0.8768013.3934011.17370K562PPIG
HOOK3ENSG00000168172.4459.195601109.67630-1.2730021.0742019.00200K562PRPF8
HOOK3ENSG00000168172.4623.97680913.80550-0.550404.882003.63770K562PSIP1
HOOK3ENSG00000168172.41113.573501910.03410-0.7784010.949509.69160K562PTBP1
HOOK3ENSG00000168172.4983.915201904.83500-0.9531016.3040015.02540K562PUS1
HOOK3ENSG00000168172.41334.352601855.85840-0.475907.054806.13680K562RBM15
HOOK3ENSG00000168172.41459.905201831.91200-0.327502.682201.85510K562RBM22
HOOK3ENSG00000168172.4577.13090833.67690-0.530604.987603.65320K562RCC2
HOOK3ENSG00000168172.41384.119101927.69680-0.477904.656703.19640K562NELFE
HOOK3ENSG00000168172.4950.079201539.41810-0.696306.071603.45600K562RECQL
HOOK3ENSG00000168172.4769.971101130.38060-0.553904.180203.17410K562RPS19
HOOK3ENSG00000168172.41120.057601576.13250-0.492803.470502.50860K562SF3B4
HOOK3ENSG00000168172.4550.95670790.30890-0.520504.307802.94550K562SRFBP1
HOOK3ENSG00000168172.41824.417601595.331500.193502.178301.33870K562SRPK2
HOOK3ENSG00000168172.41489.342901872.38450-0.330203.171102.41830K562SRSF1
HOOK3ENSG00000168172.41364.353501768.11390-0.374002.285901.34790K562SRSF5
HOOK3ENSG00000168172.41031.167701895.16010-0.878008.355207.03970K562TARDBP
HOOK3ENSG00000168172.41286.454601828.04730-0.506906.123104.83630K562TIA1
HOOK3ENSG00000168172.41420.161101793.42070-0.336702.892601.77030K562TRA2A
HOOK3ENSG00000168172.4677.26820933.69590-0.463203.758302.62490K562TRIM56
HOOK3ENSG00000168172.41159.896601517.27100-0.387503.407702.51830K562U2AF2
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for HOOK3 is not available on ENCORE database.





1 RBPs can affect the splicing of HOOK3 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEHOOK3ENSG00000168172.4chr8+428055304280559842798455427985884281223642812299-0.321000.001300.01526excludedK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for HOOK3 is not avaliable on ENCORE database.