FBXW2

General Information

Gene Name       : FBXW2
Gene ID             : ENSG00000119402.16
Essential Gene : No

Functions

Localization

Domains (AlphaFold: FBXW2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878FBXW2ENSG00000119402.1628.5426.3727.45ENCSR000AEF
HepG2FBXW2ENSG00000119402.1627.5943.9335.76ENCSR985KAT
K562FBXW2ENSG00000119402.1621.6118.8620.23ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for FBXW2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • FBXW2 RNA is bound by 22 proteins.  







eCLIP assay for FBXW2 is not avaliable on ENCORE database.





22 proteins are bound to FBXW2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr9123526651123526701-3'-UTR,intron-Distal3.456903.65873HepG2TIA1
chr9123526607123526691-3'-UTR,intron-Distal4.879176.02367K562GTF2F1
chr9123525466123525529-3'-UTR,intron-Distal3.741357.13548K562UPF1
chr9123525701123525718-3'-UTR,intron-Distal4.078933.54010K562UPF1
chr9123526559123526591-3'-UTR,intron-Distal4.802665.24231K562UPF1
chr9123521670123521743-3'-UTR,intron-Distal4.690134.85237K562UPF1
chr9123525215123525250-3'-UTR,intron-Distal4.545374.85237K562UPF1
chr9123525582123525658-3'-UTR,intron-Distal3.946124.07825K562YBX3
chr9123522857123522923-3'-UTR,intron-Distal4.249484.77384K562HNRNPC
chr9123525093123525125-3'-UTR,intron-Distal3.360403.66308K562UPF1
chr9123525299123525333-3'-UTR,intron-Distal3.141694.14964K562UPF1
chr9123526614123526677-3'-UTR,intron-Distal3.063963.46181K562DDX55
chr9123526605123526699-3'-UTR,intron-Distal4.9069510.99442K562UPF1
chr9123526609123526656-3'-UTR,intron-Distal3.041595.38148K562HNRNPL
chr9123555489123555539-5'-UTR,intron-Distal,intron-Proximal3.323975.32728HepG2DDX3X
chr9123555414123555452-5'-UTR,intron-Distal,intron-Proximal4.1157210.85246HepG2PRPF8
chr9123550256123550461-5'-UTR,CDS,intron-Distal,intron-Proximal3.231884.94600K562RBM15
chr9123555498123555546-5'-UTR,intron-Distal,intron-Proximal3.625496.05689K562GEMIN5
chr9123550222123550280-5'-UTR,CDS,intron-Distal,intron-Proximal4.479435.66624K562LIN28B
chr9123555474123555552-5'-UTR,intron-Distal,intron-Proximal3.119316.65445HepG2U2AF2
chr9123550051123550173-5'-UTR,CDS,intron-Distal3.306634.38249K562RBM15
chr9123555411123555480-5'-UTR,intron-Distal,intron-Proximal3.762555.61464K562SRSF1
chr9123555425123555480-5'-UTR,intron-Distal,intron-Proximal3.7449914.74019K562DDX3X
chr9123555480123555542-5'-UTR,intron-Distal,intron-Proximal3.8703310.65333K562DDX3X
chr9123555425123555489-5'-UTR,intron-Distal,intron-Proximal4.427206.30673HepG2DDX3X
chr9123540780123540874-CDS,intron-Distal,intron-Proximal4.9227015.70758K562SF3B4
chr9123550010123550073-CDS,intron-Distal,intron-Proximal3.745134.83899HepG2PRPF8
chr9123526983123527077-CDS,intron-Distal4.120624.48692K562YBX3
chr9123549973123550010-intron-Distal,intron-Proximal4.1890415.38930K562KHSRP
chr9123555382123555414-intron-Distal,intron-Proximal5.5449410.43516HepG2PRPF8
chr9123540471123540523-intron-Distal3.947864.79983HepG2U2AF2
chr9123550679123550707-intron-Distal4.2259117.49522K562KHSRP
chr9123550664123550744-intron-Distal4.917297.82495HepG2KHSRP
chr9123540394123540459-intron-Distal5.105106.40067K562PTBP1
chr9123550864123550932-intron-Distal4.4780520.53513K562KHSRP
chr9123555291123555367-intron-Distal,intron-Proximal3.199704.76426K562PRPF8
chr9123554945123555019-intron-Distal4.417293.75546HepG2KHSRP
chr9123539274123539355-intron-Distal3.436824.93942K562PTBP1
chr9123552810123552890-intron-Distal3.360168.78704K562TARDBP
chr9123540322123540439-intron-Distal3.559449.68763HepG2PTBP1
chr9123555056123555204-intron-Distal,intron-Proximal4.374978.25947HepG2KHSRP
chr9123555589123555628-intron-Distal,intron-Proximal4.215913.12843K562PRPF8
chr9123555542123555596-intron-Distal,intron-Proximal3.629716.26686K562SF3B4
chr9123549950123550009-intron-Distal,intron-Proximal4.3106512.08031K562PRPF8
chr9123548787123548930-intron-Distal3.433435.35459K562KHSRP
chr9123550638123550679-intron-Distal,intron-Proximal3.397509.55730K562KHSRP
chr9123555182123555237-intron-Distal3.688934.41411K562TARDBP
chr9123552708123552763-intron-Distal4.358883.03357HepG2HNRNPC
chr9123539218123539375-intron-Distal3.710998.23065HepG2PTBP1
chr9123540295123540394-intron-Distal5.0636016.59938K562PTBP1
chr9123550707123550739-intron-Distal3.6393811.69943K562KHSRP
chr9123555095123555165-intron-Distal,intron-Proximal3.278416.18146K562TARDBP
chr9123550824123550977-intron-Distal4.5921810.71900HepG2KHSRP
chr9123550755123550815-intron-Distal3.4940210.00571K562KHSRP
chr9123539223123539274-intron-Distal4.483373.42734K562PTBP1
chr9123555540123555625-intron-Distal,intron-Proximal4.1235711.32419HepG2SF3B4
chr9123554496123554615-intron-Distal3.578325.91877HepG2QKI
chr9123555372123555427-intron-Distal,intron-Proximal4.4358711.83800K562AQR
chr9123539222123539347-intron-Distal3.658656.44854HepG2PCBP2
chr9123536238123536307-intron-Distal5.152726.22016K562XRCC6
chr9123549940123549973-intron-Distal,intron-Proximal4.2471612.50932K562KHSRP
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for FBXW2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for FBXW2 is not available on ENCORE database.

  • 74 RBPs can affect the levels of FBXW2.  








The Knockdown/knockout RNA-Seq assay for FBXW2 is not available on ENCORE database.





74 RBPs can affect the gene expression of FBXW2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
FBXW2ENSG00000119402.122519.859301953.003400.367502.955901.97940HepG2ABCF1
FBXW2ENSG00000119402.122123.451801473.291000.527305.678204.31850HepG2ADAR
FBXW2ENSG00000119402.121596.628502310.20870-0.533004.443303.79060HepG2AKAP1
FBXW2ENSG00000119402.122061.987001705.820000.273503.374002.53750HepG2AKAP8L
FBXW2ENSG00000119402.122116.592402476.63930-0.226602.906002.20470HepG2AUH
FBXW2ENSG00000119402.122563.846701816.087200.497405.080804.05080HepG2CIRBP
FBXW2ENSG00000119402.121374.801901697.50900-0.304204.037803.26360HepG2CKAP4
FBXW2ENSG00000119402.121006.870101769.71900-0.8136012.1361010.81440HepG2CPSF6
FBXW2ENSG00000119402.121321.519701001.713100.399603.108801.97290HepG2CSTF2
FBXW2ENSG00000119402.121912.443802335.62600-0.288404.714103.78610HepG2DAZAP1
FBXW2ENSG00000119402.122631.611001403.557600.9068017.9533016.41450HepG2DDX21
FBXW2ENSG00000119402.121311.108502009.64750-0.616203.426802.34130HepG2DDX59
FBXW2ENSG00000119402.121415.774801900.87890-0.425103.026702.38350HepG2DDX6
FBXW2ENSG00000119402.122437.521901624.267500.5855013.9184012.63870HepG2DKC1
FBXW2ENSG00000119402.12982.382501483.51460-0.5947010.232908.95040HepG2DNAJC21
FBXW2ENSG00000119402.121131.766901470.45600-0.377706.351705.42250HepG2DNAJC2
FBXW2ENSG00000119402.121740.417701377.689600.337102.426401.56040HepG2EEF2
FBXW2ENSG00000119402.122011.243001325.095900.601909.249507.51060HepG2EIF3G
FBXW2ENSG00000119402.122532.073402019.792000.326002.136501.57210HepG2EIF4A3
FBXW2ENSG00000119402.123615.059902843.606900.346206.140505.30500HepG2ETF1
FBXW2ENSG00000119402.12616.00850999.60170-0.698409.931307.71210HepG2FAM120A
FBXW2ENSG00000119402.12966.254501207.76660-0.321902.440601.70180HepG2FUBP3
FBXW2ENSG00000119402.121662.800302037.56930-0.293201.931501.34950HepG2FXR1
FBXW2ENSG00000119402.121456.56400995.715000.548705.378904.12560HepG2GEMIN5
FBXW2ENSG00000119402.121250.631701628.98970-0.381302.847301.81250HepG2GNB2L1
FBXW2ENSG00000119402.122196.496301497.727500.552307.193106.22420HepG2HNRNPA1
FBXW2ENSG00000119402.121452.481202127.53450-0.5507014.5352013.10020HepG2HNRNPL
FBXW2ENSG00000119402.121390.470801654.94330-0.251202.831002.21710HepG2HNRNPU
FBXW2ENSG00000119402.121149.874201690.46750-0.5559014.3863012.86210HepG2ILF2
FBXW2ENSG00000119402.123186.685802049.738700.636506.794405.83970HepG2MATR3
FBXW2ENSG00000119402.121271.711402316.00940-0.8649021.3967019.40400HepG2NOL12
FBXW2ENSG00000119402.121299.857401697.54500-0.385103.217202.41280HepG2NSUN2
FBXW2ENSG00000119402.121370.180001638.09340-0.257702.822501.96600HepG2PARN
FBXW2ENSG00000119402.121353.848701880.06320-0.473708.714207.73580HepG2PCBP1
FBXW2ENSG00000119402.122909.039701831.071300.667804.998903.39500HepG2PRPF6
FBXW2ENSG00000119402.121438.250001924.40640-0.420103.709202.55080HepG2RBM27
FBXW2ENSG00000119402.122567.424802129.027700.270003.530602.93560HepG2NELFE
FBXW2ENSG00000119402.122642.233601970.692200.423004.682003.82450HepG2RPLP0
FBXW2ENSG00000119402.12942.552901216.68110-0.368302.312801.58690HepG2RRP9
FBXW2ENSG00000119402.121186.053801473.79210-0.313404.193503.42910HepG2SAFB2
FBXW2ENSG00000119402.123623.193502009.589000.850308.732007.47880HepG2SF3A3
FBXW2ENSG00000119402.121163.075101894.93020-0.704209.786808.53210HepG2SF3B1
FBXW2ENSG00000119402.121731.750802119.97380-0.291804.504303.64310HepG2SLBP
FBXW2ENSG00000119402.121036.121901713.89820-0.726106.291404.79990HepG2SMNDC1
FBXW2ENSG00000119402.121457.689602108.44480-0.532503.247202.39860HepG2SNRNP70
FBXW2ENSG00000119402.122997.089102078.919500.5276013.5201012.64430HepG2SRSF1
FBXW2ENSG00000119402.121757.119202182.96790-0.313104.344203.59110HepG2SRSF5
FBXW2ENSG00000119402.124601.694202330.609800.9814049.8391048.32750HepG2SSB
FBXW2ENSG00000119402.121833.249802482.58980-0.437409.666208.62340HepG2SUCLG1
FBXW2ENSG00000119402.12580.134401332.07130-1.1992024.2484021.77940HepG2SUPT6H
FBXW2ENSG00000119402.122236.490201587.377600.494503.965403.17800HepG2SUPV3L1
FBXW2ENSG00000119402.122525.954801868.641800.434706.998006.17560HepG2TAF15
FBXW2ENSG00000119402.121969.676401608.035100.292602.961802.44690HepG2TIAL1
FBXW2ENSG00000119402.121259.578701622.46510-0.365205.374004.63890HepG2TRIM56
FBXW2ENSG00000119402.122180.549401687.304600.369903.409602.71790HepG2U2AF1
FBXW2ENSG00000119402.121180.43290937.682900.332002.058301.40320HepG2UCHL5
FBXW2ENSG00000119402.122452.074201960.077200.323006.480705.73530HepG2ZNF622
FBXW2ENSG00000119402.124681.897903161.873200.566207.647606.75230K562AQR
FBXW2ENSG00000119402.121761.037402058.20110-0.225002.656501.71740K562BCLAF1
FBXW2ENSG00000119402.122613.295903058.19780-0.226802.552601.49020K562CPEB4
FBXW2ENSG00000119402.121363.707101869.19240-0.454905.540504.43840K562CPSF6
FBXW2ENSG00000119402.121182.886001561.45220-0.400604.565503.15690K562CSTF2
FBXW2ENSG00000119402.123655.799303164.835400.208002.569301.93840K562DDX47
FBXW2ENSG00000119402.122092.643102567.10320-0.294802.457701.66000K562FIP1L1
FBXW2ENSG00000119402.121484.978001902.05340-0.357102.977502.08910K562FMR1
FBXW2ENSG00000119402.122315.259003175.84350-0.456005.845104.74210K562GRSF1
FBXW2ENSG00000119402.121877.061802250.31220-0.261602.333501.35300K562HNRNPA1
FBXW2ENSG00000119402.122592.835503480.46500-0.424704.552003.53720K562HSPD1
FBXW2ENSG00000119402.121173.574201523.98390-0.376902.158501.34530K562KRR1
FBXW2ENSG00000119402.121887.238902294.06460-0.281603.915802.96810K562MTPAP
FBXW2ENSG00000119402.123363.770504500.63220-0.420004.678502.70580K562NOL12
FBXW2ENSG00000119402.122157.617702914.15150-0.433604.513203.42960K562PPIG
FBXW2ENSG00000119402.121129.667501596.95290-0.499405.188903.89920K562PSIP1
FBXW2ENSG00000119402.121129.380001696.49470-0.587005.153004.03600K562RPS19
FBXW2ENSG00000119402.123213.742202515.128600.353505.503004.38070K562SF3A3
FBXW2ENSG00000119402.121282.459901697.45200-0.404502.894201.89790K562SF3B1
FBXW2ENSG00000119402.121600.529902059.77890-0.363903.219102.06930K562SRSF5
FBXW2ENSG00000119402.123106.638203917.17780-0.334503.968902.18040K562SUCLG1
FBXW2ENSG00000119402.121819.984102207.52630-0.278501.951401.35050K562TARDBP
FBXW2ENSG00000119402.121716.959102129.38200-0.310603.039002.17270K562TIA1
FBXW2ENSG00000119402.121156.930701536.01930-0.408903.090102.09730K562TIAL1
FBXW2ENSG00000119402.122366.122002815.57860-0.250903.262601.87900K562TROVE2
FBXW2ENSG00000119402.122850.298502404.819600.245103.774602.79620K562WDR43
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for FBXW2 is not available on ENCORE database.





5 RBPs can affect the splicing of FBXW2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEFBXW2ENSG00000119402.12chr9-123540628123540823123538370123538504123550046123550464-0.097000.002580.04469excludedHepG2U2AF1
SEFBXW2ENSG00000119402.12chr9-123555164123555293123550293123550556123555426123555535-0.203000.000480.06830excludedK562DROSHA
SEFBXW2ENSG00000119402.12chr9-1235392081235392991235383701235385041235406281235408230.140000.000000.00000includedK562PTBP1
A3SSFBXW2ENSG00000119402.12chr9-1235383701235385521235383701235385041235406281235408000.057000.017450.08493longerK562AQR
A3SSFBXW2ENSG00000119402.12chr9-1235336881235339001235336881235337951235350311235351640.057000.000010.00007longerK562AQR
A3SSFBXW2ENSG00000119402.12chr9-123550046123550556123550046123550464123555426123555535-0.344000.000230.02373shorterK562SRSF1
MXEFBXW2ENSG00000119402.12chr9-123539208123539299123550046123550556123538370123538504123555426123555535-0.440000.000300.014412includedK562PTBP1
MXEFBXW2ENSG00000119402.12chr9-123540628123540823123550046123550556123538370123538504123555426123555535-0.094000.011350.070192includedK562AQR
MXEFBXW2ENSG00000119402.12chr9-123538370123538504123550046123550556123533625123533795123555426123555535-0.266000.002080.017222includedK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for FBXW2 is not avaliable on ENCORE database.