EXT2

General Information

Gene Name       : EXT2
Gene ID             : ENSG00000151348.13
Essential Gene : No

Functions

Localization

Domains (AlphaFold: EXT2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878EXT2ENSG00000151348.1311.368.7310.04ENCSR000AEF
HepG2EXT2ENSG00000151348.1345.5755.6250.59ENCSR985KAT
K562EXT2ENSG00000151348.1325.3225.6125.46ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for EXT2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • EXT2 RNA is bound by 16 proteins.  







eCLIP assay for EXT2 is not avaliable on ENCORE database.





16 proteins are bound to EXT2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr114426653444266595+3'-UTR3.963693.64119HepG2UPF1
chr114412925244129320+3'-UTR,5'-UTR,CDS4.026405.07098K562DDX3X
chr114426633644266422+3'-UTR4.160824.44583HepG2UPF1
chr114426619444266241+3'-UTR4.584925.29097HepG2LIN28B
chr114426583644265916+3'-UTR4.143547.73571HepG2LARP4
chr114412922644129257+3'-UTR,5'-UTR,CDS,intron-Proximal3.359643.15824K562FTO
chr114426674044266847+3'-UTR3.350183.51818HepG2LIN28B
chr114412923244129265+3'-UTR,5'-UTR,CDS,intron-Proximal3.760329.75538HepG2DDX3X
chr114411737044117403+5'-UTR,intron-Proximal3.385883.51264K562FTO
chr114411729544117362+5'-UTR4.9443065.85667HepG2DDX3X
chr114411736244117404+5'-UTR,intron-Proximal4.4161332.79480HepG2DDX3X
chr114411724544117372+5'-UTR5.4461713.11144K562DDX3X
chr114411729844117361+5'-UTR3.789397.25768HepG2RPS3
chr114411737244117402+5'-UTR3.702894.26442K562DDX3X
chr114411730444117370+5'-UTR3.139486.08453K562FTO
chr114411736644117403+5'-UTR,intron-Proximal3.949074.92654HepG2RPS3
chr114411723744117295+5'-UTR4.6447925.79054HepG2DDX3X
chr114414633844146404+CDS,intron-Proximal3.270187.87397K562SND1
chr114414847044148505+CDS3.125493.95762K562SND1
chr114419322344193296+CDS,intron-Proximal5.414504.75872K562DDX24
chr114413573444135762+CDS,intron-Proximal4.053005.23222HepG2SND1
chr114414836644148417+CDS4.068363.18234K562BUD13
chr114413573444135808+CDS,intron-Proximal4.104526.28735K562DDX24
chr114426573944265793+CDS3.339703.54552HepG2LARP4
chr114413580244135833+CDS4.767297.41523K562YBX3
chr114426574244265816+CDS3.235284.98507K562PUM2
chr114425568544255723+CDS3.652724.15748K562SND1
chr114425390244253973+CDS,intron-Proximal3.667675.29565HepG2SND1
chr114413075144130815+CDS4.100294.72754K562YBX3
chr114419316044193231+CDS,intron-Proximal3.476063.69481K562UCHL5
chr114413578644135802+CDS4.454334.96452K562YBX3
chr114421939744219516+CDS,intron-Distal3.668665.16993HepG2SND1
chr114413074344130760+CDS,intron-Proximal3.960153.31432HepG2SND1
chr114414643844146513+CDS3.885874.38503K562SND1
chr114413575644135849+CDS3.660528.91754K562SND1
chr114413579644135849+CDS3.060805.16993HepG2SND1
chr114412975844129799+CDS,intron-Proximal3.528184.39950HepG2SND1
chr114415164644151695+CDS,intron-Proximal4.350444.67299K562DDX24
chr114414837844148432+CDS3.982206.18002K562SND1
chr114421937844219408+CDS,intron-Distal,intron-Proximal3.406203.88509K562SND1
chr114412941344129496+CDS3.955496.96497HepG2DDX3X
chr114414839244148451+CDS4.632135.54337HepG2SND1
chr114412960444129796+CDS4.2202319.78864K562YBX3
chr114412927744129318+CDS5.2071510.74913K562YBX3
chr114412954044129661+CDS3.601937.79897K562SND1
chr114426569844265739+CDS,intron-Proximal3.291223.30795HepG2SND1
chr114413077544130834+CDS,intron-Proximal3.687227.77650HepG2SND1
chr114413637644136511+intron-Distal4.254323.55787K562PTBP1
chr114415174844151804+intron-Distal,intron-Proximal3.158403.49168K562AQR
chr114419233844192476+intron-Distal4.671343.80954K562HNRNPL
chr114417185644171910+intron-Distal5.432626.22530K562AQR
chr114412783644127931+intron-Distal4.877908.54663K562PTBP1
chr114412784844127928+intron-Distal3.507304.08242HepG2PTBP1
chr114413643544136635+intron-Distal4.197764.18579K562MATR3
chr114415168844151748+intron-Proximal4.871339.46915K562AQR
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for EXT2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for EXT2 is not available on ENCORE database.

  • 94 RBPs can affect the levels of EXT2.  








The Knockdown/knockout RNA-Seq assay for EXT2 is not available on ENCORE database.





94 RBPs can affect the gene expression of EXT2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
EXT2ENSG00000151348.91558.934801807.21080-0.213202.403801.83020HepG2ACO1
EXT2ENSG00000151348.94801.161202700.799600.8299011.0537010.05900HepG2AKAP1
EXT2ENSG00000151348.91285.251701815.75860-0.498509.279807.97560HepG2AKAP8L
EXT2ENSG00000151348.93223.561902730.615500.239303.307302.56770HepG2AUH
EXT2ENSG00000151348.92455.593401880.010700.385202.370401.47490HepG2CCAR1
EXT2ENSG00000151348.9986.809801598.08460-0.695504.679103.68000HepG2CNOT7
EXT2ENSG00000151348.91118.99860796.269800.490804.166503.33890HepG2CPSF6
EXT2ENSG00000151348.92899.703702371.615300.289904.248503.48290HepG2CELF1
EXT2ENSG00000151348.93248.957702549.793500.349508.549107.35560HepG2DAZAP1
EXT2ENSG00000151348.91953.025001592.247100.294502.609401.72390HepG2DDX24
EXT2ENSG00000151348.91061.908001565.89870-0.560303.917102.41760HepG2DDX27
EXT2ENSG00000151348.91754.860902587.29170-0.560105.718304.84950HepG2DDX3X
EXT2ENSG00000151348.91030.916601337.49500-0.375603.066201.70650HepG2DDX47
EXT2ENSG00000151348.93656.883002222.230900.718508.346907.32900HepG2DDX6
EXT2ENSG00000151348.91350.335501729.02870-0.356604.947004.08970HepG2DKC1
EXT2ENSG00000151348.91156.694401416.35360-0.292204.034103.27680HepG2DNAJC2
EXT2ENSG00000151348.91416.413502136.58840-0.593106.234105.36320HepG2EIF2S1
EXT2ENSG00000151348.91471.915802298.80390-0.643205.126104.20880HepG2EIF4B
EXT2ENSG00000151348.91928.072802515.76490-0.383806.342205.16590HepG2EIF4G1
EXT2ENSG00000151348.91189.837303135.15330-1.3978073.3550071.06630HepG2ETF1
EXT2ENSG00000151348.91404.881101766.02870-0.330103.038102.16470HepG2EWSR1
EXT2ENSG00000151348.92131.214101546.807900.462303.574602.70720HepG2FIP1L1
EXT2ENSG00000151348.91447.349601189.980500.282402.153501.45320HepG2FUBP3
EXT2ENSG00000151348.92699.238501858.973200.537903.725702.43510HepG2FUS
EXT2ENSG00000151348.91939.165502382.03650-0.296802.000401.40800HepG2FXR1
EXT2ENSG00000151348.92505.781401692.837100.565706.037104.51220HepG2GNB2L1
EXT2ENSG00000151348.91302.712301725.41050-0.405406.461305.04690HepG2HDGF
EXT2ENSG00000151348.9926.394901442.65250-0.639008.077207.05840HepG2HNRNPA1
EXT2ENSG00000151348.91380.857701656.69750-0.262702.955402.21510HepG2HNRNPF
EXT2ENSG00000151348.9382.78020861.34900-1.1701015.9628014.62580HepG2HNRNPLL
EXT2ENSG00000151348.91358.939801594.07780-0.230202.384001.81810HepG2HNRNPU
EXT2ENSG00000151348.91312.606201631.37230-0.313702.976202.22760HepG2IGF2BP1
EXT2ENSG00000151348.91269.261801628.29720-0.359406.250705.19260HepG2ILF2
EXT2ENSG00000151348.91587.207902382.86610-0.586206.104205.13810HepG2MAGOH
EXT2ENSG00000151348.91805.383501251.774700.528206.534705.34350HepG2MSI2
EXT2ENSG00000151348.91431.069201051.146300.445004.605203.03920HepG2NAA15
EXT2ENSG00000151348.91377.281602452.77960-0.8326011.174409.94610HepG2NCBP2
EXT2ENSG00000151348.9920.159501460.49720-0.666503.903402.83530HepG2PABPC1
EXT2ENSG00000151348.92678.094902184.630400.293701.976701.35760HepG2PABPC4
EXT2ENSG00000151348.91257.850602176.32760-0.7909017.2146015.90820HepG2PCBP1
EXT2ENSG00000151348.9689.46950929.79510-0.431404.256202.71800HepG2PKM
EXT2ENSG00000151348.91650.832001224.399600.431006.671605.53010HepG2PRPF4
EXT2ENSG00000151348.91408.893402214.38960-0.6523014.8215013.75070HepG2PTBP1
EXT2ENSG00000151348.92187.504702562.27540-0.228102.751802.16010HepG2PUM1
EXT2ENSG00000151348.91118.510301840.77150-0.7187020.3076018.91380HepG2PUS1
EXT2ENSG00000151348.91740.194602398.46260-0.462907.416706.46720HepG2QKI
EXT2ENSG00000151348.9535.805701698.36950-1.6644019.1956017.50200HepG2RAVER1
EXT2ENSG00000151348.92212.925702620.39940-0.243802.739902.22380HepG2RBM22
EXT2ENSG00000151348.91007.324101624.17640-0.689207.313305.60520HepG2RCC2
EXT2ENSG00000151348.91762.355502464.49030-0.483808.227707.38470HepG2NELFE
EXT2ENSG00000151348.91983.251302295.17940-0.210702.525701.93320HepG2RECQL
EXT2ENSG00000151348.9986.652901784.69600-0.8551014.3486013.02160HepG2RPLP0
EXT2ENSG00000151348.9826.071901094.09050-0.405403.779703.07140HepG2RPS19
EXT2ENSG00000151348.91370.676501844.57240-0.428404.120203.15170HepG2RPS2
EXT2ENSG00000151348.91471.149101882.96650-0.356103.008001.88670HepG2RPS5
EXT2ENSG00000151348.91127.289201419.59500-0.332604.564403.77110HepG2SAFB2
EXT2ENSG00000151348.9848.050001097.96010-0.372602.685501.76220HepG2SERBP1
EXT2ENSG00000151348.92216.654901526.593400.538003.980403.16490HepG2SF3A3
EXT2ENSG00000151348.91971.198802305.65390-0.226102.308501.76160HepG2SF3B4
EXT2ENSG00000151348.91393.400001655.48450-0.248603.400902.69990HepG2SMN1
EXT2ENSG00000151348.91283.90620948.602700.436602.114901.43490HepG2SNRNP70
EXT2ENSG00000151348.91977.993402959.62950-0.5814017.3307016.35940HepG2SRFBP1
EXT2ENSG00000151348.91110.936902383.22560-1.1011042.6020040.55070HepG2SRSF5
EXT2ENSG00000151348.91258.214601627.65680-0.371405.514904.58860HepG2SRSF7
EXT2ENSG00000151348.91506.188401957.77130-0.378305.063804.35830HepG2SRSF9
EXT2ENSG00000151348.91836.023002569.63250-0.4850011.0400010.14920HepG2SSB
EXT2ENSG00000151348.9961.930101393.46530-0.534703.261401.87360HepG2SSRP1
EXT2ENSG00000151348.9977.277301395.36290-0.513803.578902.31270HepG2STIP1
EXT2ENSG00000151348.92153.691302710.29250-0.331606.007305.15440HepG2SUCLG1
EXT2ENSG00000151348.9938.235301410.32350-0.588004.002602.39530HepG2SUGP2
EXT2ENSG00000151348.91291.646101044.384100.306502.539501.63760HepG2SUPT6H
EXT2ENSG00000151348.91233.068601666.00420-0.434103.075602.36660HepG2SUPV3L1
EXT2ENSG00000151348.93463.383002162.866400.6791016.9487015.72890HepG2TAF15
EXT2ENSG00000151348.91200.29480839.705400.515304.833703.91170HepG2TARDBP
EXT2ENSG00000151348.92486.120601987.606100.322803.325002.41290HepG2TIA1
EXT2ENSG00000151348.9998.906901548.93280-0.632909.521008.69050HepG2TIAL1
EXT2ENSG00000151348.91908.428002358.17050-0.305302.773901.89920HepG2TUFM
EXT2ENSG00000151348.91752.679402496.18210-0.510204.428203.35250HepG2UBE2L3
EXT2ENSG00000151348.91079.029101639.99830-0.604006.110905.04700HepG2XRN2
EXT2ENSG00000151348.91027.690501208.34230-0.233602.420201.78610HepG2ZC3H8
EXT2ENSG00000151348.92113.737501488.981100.5054013.2431012.27140HepG2ZNF622
EXT2ENSG00000151348.91168.402001696.63980-0.538103.804302.26500HepG2ZRANB2
EXT2ENSG00000151348.91596.406001222.246700.385205.522504.76390K562AGGF1
EXT2ENSG00000151348.91377.639601065.501100.370604.620103.16380K562CPEB4
EXT2ENSG00000151348.9743.20440536.722600.469504.023803.07860K562CPSF6
EXT2ENSG00000151348.92877.161102259.506100.348504.060902.87060K562CELF1
EXT2ENSG00000151348.91280.123701034.549000.307202.566101.56360K562DDX3X
EXT2ENSG00000151348.91370.197801128.264100.280202.717002.00350K562EIF2S2
EXT2ENSG00000151348.9319.48160479.74440-0.586502.505701.55210K562EIF3A
EXT2ENSG00000151348.9876.922901080.84870-0.301602.082401.36570K562EIF4A3
EXT2ENSG00000151348.9622.35820813.54360-0.386502.805002.20420K562HNRNPC
EXT2ENSG00000151348.9555.32070726.46270-0.387602.582201.48450K562HNRNPF
EXT2ENSG00000151348.91174.823901443.40620-0.297002.884301.97210K562HNRNPU
EXT2ENSG00000151348.91622.283901264.361500.359502.263101.36210K562IGF2BP2
EXT2ENSG00000151348.91862.601501512.013000.300702.749001.84410K562MBNL1
EXT2ENSG00000151348.9557.61730729.41800-0.387502.466501.61890K562PSIP1
EXT2ENSG00000151348.91895.551901261.299000.587606.883206.07170K562PUS1
EXT2ENSG00000151348.91707.036501228.927300.474006.765805.86470K562RBM15
EXT2ENSG00000151348.91161.16690628.496700.885503.637202.19620K562SF1
EXT2ENSG00000151348.91327.195301034.071600.359904.105903.12400K562SF3A3
EXT2ENSG00000151348.91255.761601059.429600.245202.577201.66890K562SRPK2
EXT2ENSG00000151348.9806.652501280.62580-0.666807.631106.38790K562TARDBP
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for EXT2 is not available on ENCORE database.





1 RBPs can affect the splicing of EXT2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEEXT2ENSG00000151348.9chr11+4411764944117871441170984411740244129232441297980.129000.000350.00842includedHepG2U2AF1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for EXT2 is not avaliable on ENCORE database.