EXOSC3

General Information

Gene Name : EXOSC3
Gene ID : ENSG00000107371.12
Essential Gene : Yes

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: EXOSC3)

Not Available

Antibody Validation

Not Avaiable

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	EXOSC3	ENSG00000107371.12	36.74	40.31	38.53	ENCSR000AEF
HepG2	EXOSC3	ENSG00000107371.12	47.13	57.80	52.47	ENCSR985KAT
K562	EXOSC3	ENSG00000107371.12	65.28	53.31	59.30	ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.

eCLIP

No eCLIP experiment available

Antibody Validation

No Antibody Primary Validation image or Secondary image available

KD RNA-Seq

GeneName	Cell_Line	Method	Sample_reps	Control_reps	KD%	Status	Project
EXOSC3	K562	CRISPR	BGKcLV40-37,BGKcLV40-38	BGKcLV40-1,BGKcLV40-2	0.0,0.0	NotSatisfied	ENCORE2
EXOSC3	HepG2	CRISPR	BGHcLV41-57,BGHcLV41-58	BGHcLV41-1,BGHcLV41-2	0.0,0.0	NotSatisfied	ENCORE2
EXOSC3	HepG2	CRISPR	BGHcLV45-33,BGHcLV45-34	BGHcLV45-1,BGHcLV45-2	0.0,0.0	NotSatisfied	ENCORE2
EXOSC3	HepG2	CRISPR	BGHcLV45-35,BGHcLV45-36	BGHcLV45-1,BGHcLV45-2	0.0,0.0	NotSatisfied	ENCORE2
EXOSC3	HepG2	CRISPR	BGHcLV47-25,BGHcLV47-26	BGHcLV47-1,BGHcLV47-2		NotSatisfied	ENCORE2

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for EXOSC3 is not avaliable on ENCORE database.

Proteins bound to RNA

EXOSC3 RNA is bound by 11 proteins.

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eCLIP assay for EXOSC3 is not avaliable on ENCORE database.

11 proteins are bound to EXOSC3 RNA:

Show entries

Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr9	37780500	37780570	-	3'-UTR,5'-UTR,intron-Distal,intron-Proximal	3.31375	18.69899	K562	PABPC4
chr9	37784966	37785012	-	CDS,intron-Distal	3.78115	9.88402	K562	DDX3X
chr9	37784917	37784966	-	CDS,intron-Distal	3.01105	7.86233	K562	DDX3X
chr9	37780505	37780584	-	3'-UTR,5'-UTR,intron-Distal,intron-Proximal	4.80399	7.83850	HepG2	SUB1
chr9	37794264	37794340	-	intron-Distal	5.10267	6.97910	HepG2	PCBP2
chr9	37780851	37780902	-	3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal	4.56419	6.86842	HepG2	U2AF2
chr9	37782031	37782120	-	CDS,intron-Distal	3.54267	6.01266	K562	LIN28B
chr9	37779956	37780086	-	3'-UTR,intron-Distal	3.52291	5.45345	K562	HNRNPL
chr9	37784851	37784899	-	CDS,intron-Distal	3.19692	5.44096	K562	DDX3X
chr9	37784784	37785000	-	CDS,intron-Distal,intron-Proximal	3.02734	5.18108	K562	HNRNPM
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 16 entries

eCLIP assay for EXOSC3 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for EXOSC3 is not available on ENCORE database.
77 RBPs can affect the levels of EXOSC3.

CanvasJS.com

The Knockdown/knockout RNA-Seq assay for EXOSC3 is not available on ENCORE database.

77 RBPs can affect the gene expression of EXOSC3 :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
EXOSC3	ENSG00000107371.8	340.17660	808.85310	-1.24960	20.44110	18.89770	K562	HNRNPC
EXOSC3	ENSG00000107371.8	1169.90440	616.96580	0.92300	19.57920	18.08190	K562	FXR1
EXOSC3	ENSG00000107371.8	355.17690	741.03760	-1.06100	13.63960	11.18250	K562	TRIM56
EXOSC3	ENSG00000107371.8	140.48410	319.92720	-1.18730	11.64120	10.74140	HepG2	TIAL1
EXOSC3	ENSG00000107371.8	491.59300	874.39060	-0.83080	11.35300	9.74900	K562	CPSF6
EXOSC3	ENSG00000107371.8	385.70090	725.21970	-0.91090	10.86910	8.81810	K562	PSIP1
EXOSC3	ENSG00000107371.8	183.11350	393.56910	-1.10390	9.11460	8.04550	HepG2	HNRNPLL
EXOSC3	ENSG00000107371.8	402.86250	754.02120	-0.90430	9.78800	7.95890	K562	FTO
EXOSC3	ENSG00000107371.8	362.65660	697.54110	-0.94370	9.76090	7.90780	K562	TIAL1
EXOSC3	ENSG00000107371.8	880.83940	1235.46460	-0.48810	8.98780	7.74740	K562	NSUN2
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 96 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for EXOSC3 is not available on ENCORE database.

16 RBPs can affect the splicing of EXOSC3 :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	FDR	is_included	Cell Line	Affected by RBP
SE	EXOSC3	ENSG00000107371.8	chr9	-	37781982	37782134	37780687	37780877	37783910	37784060	-0.14600	0.00000	excluded	K562	SRSF1
SE	EXOSC3	ENSG00000107371.8	chr9	-	37781982	37782134	37780687	37780877	37783910	37784060	-0.14500	0.00003	excluded	K562	SF3B4
SE	EXOSC3	ENSG00000107371.8	chr9	-	37781982	37782134	37780687	37780877	37783910	37784060	-0.26600	0.00000	excluded	K562	PRPF8
SE	EXOSC3	ENSG00000107371.8	chr9	-	37781982	37782134	37780687	37780877	37783910	37784060	-0.25200	0.00098	excluded	HepG2	PRPF8
SE	EXOSC3	ENSG00000107371.8	chr9	-	37781982	37782134	37780687	37780877	37783910	37784060	-0.13900	0.00000	excluded	K562	AQR
SE	EXOSC3	ENSG00000107371.8	chr9	-	37781982	37782134	37780687	37780877	37783910	37784060	-0.22500	0.00000	excluded	K562	EFTUD2
SE	EXOSC3	ENSG00000107371.8	chr9	-	37781982	37782134	37780687	37780877	37783910	37784060	0.10900	0.00003	included	K562	HNRNPM
SE	EXOSC3	ENSG00000107371.8	chr9	-	37781982	37782134	37780687	37780877	37783910	37784060	-0.24700	0.00000	excluded	HepG2	SRSF1
SE	EXOSC3	ENSG00000107371.8	chr9	-	37781982	37782134	37780687	37780877	37783910	37784060	-0.14000	0.00000	excluded	K562	HNRNPU
SE	EXOSC3	ENSG00000107371.8	chr9	-	37781982	37782134	37780687	37780877	37783910	37784060	-0.13100	0.00000	excluded	K562	PTBP1

Showing 1 to 10 of 24 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

EXOSC3

General Information

Functions

Localization

Domains (AlphaFold: EXOSC3)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for EXOSC3 is not avaliable on ENCORE database.

11 proteins are bound to EXOSC3 RNA:

eCLIP assay for EXOSC3 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for EXOSC3 is not available on ENCORE database.

77 RBPs can affect the gene expression of EXOSC3 :

The Knockdown/knockout RNA-Seq assay for EXOSC3 is not available on ENCORE database.

16 RBPs can affect the splicing of EXOSC3 :

The Knockdown/knockout RNA-Seq assay for EXOSC3 is not avaliable on ENCORE database.