EXOC6

General Information

Gene Name       : EXOC6
Gene ID             : ENSG00000138190.16
Essential Gene : No

Functions

Localization

Domains (AlphaFold: EXOC6)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878EXOC6ENSG00000138190.1650.0213.5231.77ENCSR000AEF
HepG2EXOC6ENSG00000138190.1611.8813.8612.87ENCSR985KAT
K562EXOC6ENSG00000138190.1629.1728.7728.97ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for EXOC6 is not avaliable on ENCORE database.



Proteins bound to RNA
  • EXOC6 RNA is bound by 18 proteins.  







eCLIP assay for EXOC6 is not avaliable on ENCORE database.





18 proteins are bound to EXOC6 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr109481907594819226+3'-UTR4.646847.91848K562PUM2
chr109477394594774012+3'-UTR,CDS,intron-Proximal3.066023.93753K562U2AF2
chr109460823894608325+5'-UTR,CDS,intron-Distal4.127193.72434HepG2NCBP2
chr109468809394688172+5'-UTR,CDS,intron-Proximal3.837627.58784HepG2BCLAF1
chr109470048694700567+CDS3.635435.56491HepG2BCLAF1
chr109467558694675668+CDS4.496787.97334HepG2BCLAF1
chr109471534794715411+CDS4.529825.84664K562PUM2
chr109466933094669389+CDS,intron-Proximal4.170813.87995K562UCHL5
chr109473387694733932+CDS4.791073.89826HepG2BCLAF1
chr109467976294679806+CDS,intron-Distal4.756604.34038HepG2BCLAF1
chr109466936894669389+CDS,intron-Proximal4.650845.23259HepG2BCLAF1
chr109465474894654777+CDS3.089927.37965K562YBX3
chr109471203294712082+CDS4.902275.68196HepG2BCLAF1
chr109469406694694124+CDS,intron-Distal,intron-Proximal3.165305.40132HepG2BCLAF1
chr109465473894654748+CDS3.161856.15304K562YBX3
chr109469562194695676+CDS,intron-Distal,intron-Proximal4.723465.33214K562PRPF8
chr109470055694700610+CDS,intron-Proximal4.922734.35676HepG2PRPF8
chr109465323494653276+CDS3.593114.09885HepG2BCLAF1
chr109465935594659399+CDS,intron-Proximal4.130119.80976HepG2BCLAF1
chr109465471494654782+CDS,intron-Proximal5.0186014.17165HepG2BCLAF1
chr109470805394708130+CDS3.966637.23562HepG2BCLAF1
chr109467556394675638+CDS4.316315.20626K562PUM2
chr109461938694619444+intron-Distal3.839983.29248HepG2SUGP2
chr109479947194799556+intron-Distal5.527105.81225K562PTBP1
chr109474579194745853+intron-Distal4.322235.25174K562KHSRP
chr109479946994799565+intron-Distal3.854873.89405HepG2PTBP1
chr109468081694680913+intron-Distal4.228834.76003K562KHSRP
chr109475565494755750+intron-Distal4.067874.31512K562KHSRP
chr109461754394617622+intron-Distal5.2863810.28730K562TARDBP
chr109466294094663032+intron-Distal3.363004.76004K562KHSRP
chr109466880094669015+intron-Distal3.966618.34041K562KHSRP
chr109467751494677580+intron-Distal4.048623.31709K562ILF3
chr109470829694708437+intron-Distal4.670795.51743K562QKI
chr109461817894618278+intron-Distal3.396754.24981K562MATR3
chr109466556394665655+intron-Distal5.095838.72817K562KHSRP
chr109469550794695570+intron-Distal,intron-Proximal3.663363.06150K562KHSRP
chr109467984394679902+intron-Distal,intron-Proximal3.090073.90146K562KHSRP
chr109473157694731657+intron-Distal3.856813.66668K562KHSRP
chr109461816994618283+intron-Distal4.094668.23065HepG2PTBP1
chr109464997594650080+intron-Distal4.249744.72162K562KHSRP
chr109474852394748665+intron-Distal4.615395.41154K562HNRNPL
chr109461964294619735+intron-Distal4.056057.30349K562TARDBP
chr109478159894781706+intron-Distal4.342005.46313K562KHSRP
chr109474857594748648+intron-Distal5.8048212.73974K562AGGF1
chr109461890494618964+intron-Distal3.946833.54208HepG2SUGP2
chr109474851494748594+intron-Distal3.560455.12612HepG2HNRNPL
chr109461818394618238+intron-Distal3.542923.68462HepG2MATR3
chr109459534194595408+intron-Distal3.054683.07368K562TARDBP
chr109477999894780142+intron-Distal3.720403.49896K562KHDRBS1
chr109467752294677586+intron-Distal4.412745.18400HepG2ILF3
chr109461648994616611+intron-Distal3.208765.36888K562KHSRP
chr109461777094617822+intron-Distal3.239323.84025HepG2SUGP2
chr109461842394618468+intron-Distal3.985843.79098HepG2SUGP2
chr109474585394745976+intron-Distal5.230959.71683K562KHSRP
chr109461895294619132+intron-Distal4.579685.84413K562HNRNPM
chr109476111194761214+intron-Distal3.858963.19026HepG2HNRNPL
chr109463182694631966+intron-Distal3.611603.90146K562KHSRP
chr109466548094665563+intron-Distal3.140954.56635K562KHSRP
chr109461816494618271+intron-Distal3.8100013.82626K562PTBP1
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for EXOC6 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for EXOC6 is not available on ENCORE database.

  • 78 RBPs can affect the levels of EXOC6.  








The Knockdown/knockout RNA-Seq assay for EXOC6 is not available on ENCORE database.





78 RBPs can affect the gene expression of EXOC6 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
EXOC6ENSG00000138190.12741.40720545.444700.442703.456301.89950HepG2ATP5C1
EXOC6ENSG00000138190.12856.12650675.252000.342303.362402.61830HepG2AUH
EXOC6ENSG00000138190.12424.00290545.26110-0.362902.049801.52920HepG2BOP1
EXOC6ENSG00000138190.12903.84410513.946000.8144011.7656010.35300HepG2CALR
EXOC6ENSG00000138190.12454.77300743.13440-0.708505.017503.68840HepG2CCAR1
EXOC6ENSG00000138190.12849.48160500.562500.762907.928806.81450HepG2CPSF6
EXOC6ENSG00000138190.12489.83660340.547200.524302.623701.31950HepG2CSTF2T
EXOC6ENSG00000138190.12859.23120605.309100.505307.113806.00500HepG2DAZAP1
EXOC6ENSG00000138190.12309.67570417.34440-0.430503.447502.52800HepG2DDX19B
EXOC6ENSG00000138190.12569.90490735.80330-0.368601.874401.34420HepG2EIF4A3
EXOC6ENSG00000138190.12512.28250349.631300.551004.107802.75210HepG2FASTKD2
EXOC6ENSG00000138190.12722.52170360.072801.0047013.1006011.45000HepG2FUBP3
EXOC6ENSG00000138190.12419.10810742.41620-0.824908.014306.88470HepG2FXR1
EXOC6ENSG00000138190.12501.82150688.68860-0.456702.764402.09950HepG2G3BP1
EXOC6ENSG00000138190.12341.32320501.67720-0.555602.739501.63250HepG2GRSF1
EXOC6ENSG00000138190.12715.91270556.282800.363903.008802.03940HepG2HNRNPA2B1
EXOC6ENSG00000138190.12258.78480429.86980-0.732105.222804.29350HepG2HNRNPC
EXOC6ENSG00000138190.12551.10070697.38600-0.339601.900601.31610HepG2HNRNPK
EXOC6ENSG00000138190.12765.76860541.465900.499903.517002.81710HepG2HNRNPLL
EXOC6ENSG00000138190.12277.65940421.02130-0.600603.908802.79750HepG2HNRNPM
EXOC6ENSG00000138190.12317.61350427.02690-0.427103.032202.39980HepG2HNRNPU
EXOC6ENSG00000138190.12525.76820784.30950-0.577003.667202.71220HepG2LARP4
EXOC6ENSG00000138190.12397.35330742.67550-0.902309.082207.90670HepG2MAGOH
EXOC6ENSG00000138190.12519.47600746.82870-0.523703.314002.62930HepG2MATR3
EXOC6ENSG00000138190.12525.34080764.41780-0.541103.768803.03370HepG2NCBP2
EXOC6ENSG00000138190.12403.50420572.95630-0.505803.783403.09860HepG2PUF60
EXOC6ENSG00000138190.12491.24940647.94860-0.399402.715402.20070HepG2RBM22
EXOC6ENSG00000138190.12800.20750627.480400.350702.516201.86990HepG2RBM25
EXOC6ENSG00000138190.12575.59520710.47010-0.303702.211101.71670HepG2NELFE
EXOC6ENSG00000138190.12545.45640661.72660-0.278801.879301.35760HepG2RECQL
EXOC6ENSG00000138190.12248.02920359.11650-0.533903.136502.48780HepG2RPS19
EXOC6ENSG00000138190.12897.94190535.917700.744508.008606.86550HepG2SF3B1
EXOC6ENSG00000138190.12549.33790664.63590-0.274901.834801.33650HepG2SF3B4
EXOC6ENSG00000138190.121143.90990731.858700.6442012.1760011.32350HepG2SRFBP1
EXOC6ENSG00000138190.12410.48030565.69990-0.462704.089603.35620HepG2SRSF5
EXOC6ENSG00000138190.12622.83660431.517700.529302.502001.36100HepG2SUB1
EXOC6ENSG00000138190.12474.92060623.59300-0.392902.810002.24540HepG2TAF15
EXOC6ENSG00000138190.12194.64800414.89020-1.0919012.0773011.16080HepG2TIAL1
EXOC6ENSG00000138190.12415.48510556.47880-0.421503.613802.83110HepG2UPF1
EXOC6ENSG00000138190.12229.92870537.25940-1.2244019.3960018.02920HepG2UTP3
EXOC6ENSG00000138190.12671.38430453.869100.564802.940001.64030HepG2XRCC5
EXOC6ENSG00000138190.12952.52370612.021100.6381011.7905010.85600HepG2ZNF622
EXOC6ENSG00000138190.12685.781701234.62110-0.8482018.1877016.85410K562AGGF1
EXOC6ENSG00000138190.12972.466201284.67120-0.401703.470802.73650K562AKAP8L
EXOC6ENSG00000138190.12592.918701597.00140-1.4295031.0623029.29050K562AQR
EXOC6ENSG00000138190.12974.06980809.704600.266502.295501.42310K562BCLAF1
EXOC6ENSG00000138190.121501.852501091.959500.459703.997802.94700K562BOP1
EXOC6ENSG00000138190.121223.880501556.38040-0.346704.009702.66610K562CPEB4
EXOC6ENSG00000138190.121687.544901161.106300.539307.134305.86710K562CPSF6
EXOC6ENSG00000138190.12570.75480751.10820-0.396103.546502.01560K562DDX6
EXOC6ENSG00000138190.121170.229401382.44850-0.240402.177801.41140K562DKC1
EXOC6ENSG00000138190.12776.13880939.97570-0.276302.328401.59560K562EIF3G
EXOC6ENSG00000138190.12499.50250773.98790-0.631806.268205.04180K562EIF4A3
EXOC6ENSG00000138190.12899.649201239.98600-0.462904.212803.15030K562FIP1L1
EXOC6ENSG00000138190.121271.321801001.242200.344402.218401.40400K562FTO
EXOC6ENSG00000138190.12895.847101509.07860-0.7523011.456509.89410K562GRSF1
EXOC6ENSG00000138190.12360.65140845.51310-1.2292013.3558012.12610K562HNRNPC
EXOC6ENSG00000138190.12983.355401455.40290-0.565607.141905.36400K562HNRNPL
EXOC6ENSG00000138190.12596.15400857.21360-0.524004.005602.16990K562LIN28B
EXOC6ENSG00000138190.12848.730701114.01290-0.392403.483302.53510K562MAGOH
EXOC6ENSG00000138190.12693.290701112.77170-0.6826012.7118011.12980K562MTPAP
EXOC6ENSG00000138190.121027.017801236.38840-0.267703.264902.46000K562NSUN2
EXOC6ENSG00000138190.12570.01860832.25050-0.546004.396702.39920K562NUSAP1
EXOC6ENSG00000138190.12678.126501182.27720-0.801904.033002.78090K562PABPN1
EXOC6ENSG00000138190.12752.960101015.76550-0.431902.959402.09890K562PCBP3
EXOC6ENSG00000138190.12617.00560825.36420-0.419702.905601.44230K562PHF6
EXOC6ENSG00000138190.12587.65170779.13280-0.406903.344202.45840K562POLR2G
EXOC6ENSG00000138190.121066.941901407.59690-0.399803.385502.46260K562PPIG
EXOC6ENSG00000138190.12785.552301405.86480-0.839703.972802.10920K562PPP1R8
EXOC6ENSG00000138190.12560.30170744.60070-0.410302.030101.38320K562PRPF8
EXOC6ENSG00000138190.12555.32590758.04800-0.449002.147001.35960K562PSIP1
EXOC6ENSG00000138190.121360.400101082.312400.329802.969602.28400K562PTBP1
EXOC6ENSG00000138190.121724.244902072.18140-0.265202.012201.31500K562PUF60
EXOC6ENSG00000138190.122673.794802204.087400.278602.779001.70900K562PUM1
EXOC6ENSG00000138190.12852.317301241.36970-0.542507.298406.36630K562RBM15
EXOC6ENSG00000138190.12727.989101037.96130-0.511804.859903.70760K562RBM22
EXOC6ENSG00000138190.12529.78460691.41310-0.384102.464901.53390K562RCC2
EXOC6ENSG00000138190.12597.59740899.35480-0.589707.038905.63700K562SF3B4
EXOC6ENSG00000138190.12717.796401318.55240-0.877304.340702.56050K562SFPQ
EXOC6ENSG00000138190.12797.738901241.65420-0.638302.439801.31750K562SNRNP200
EXOC6ENSG00000138190.12444.27460655.46260-0.561104.335102.96560K562SRFBP1
EXOC6ENSG00000138190.12782.596301001.95260-0.356502.551001.55010K562SRSF5
EXOC6ENSG00000138190.12716.422501073.86440-0.583905.691304.65570K562TARDBP
EXOC6ENSG00000138190.12810.826701035.84570-0.353302.907302.06600K562TIA1
EXOC6ENSG00000138190.12360.85840729.14060-1.014809.848507.98470K562TIAL1
EXOC6ENSG00000138190.12557.37000774.38600-0.474403.571402.47080K562TRIM56
EXOC6ENSG00000138190.12532.51030838.43270-0.654905.360103.73620K562U2AF1
EXOC6ENSG00000138190.12440.13290865.81650-0.9761016.0599014.09550K562U2AF2
EXOC6ENSG00000138190.12736.314701121.75460-0.607407.482406.00150K562WDR3
EXOC6ENSG00000138190.121125.851701799.02280-0.676209.737508.00460K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for EXOC6 is not available on ENCORE database.





10 RBPs can affect the splicing of EXOC6 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEEXOC6ENSG00000138190.12chr10+946939009469394794688095946881799469406694694187-0.195000.001130.02318excludedK562SF3B4
SEEXOC6ENSG00000138190.12chr10+946955709469564294694066946941879470048394700581-0.220000.000380.00949excludedK562SF3B4
SEEXOC6ENSG00000138190.12chr10+946939009469394794687997946881799469406694694187-0.079000.011520.09086excludedK562AQR
SEEXOC6ENSG00000138190.12chr10+946797389467980794675514946756709468809594688179-0.209000.000020.00058excludedK562PUS1
SEEXOC6ENSG00000138190.12chr10+9463291594633069946082719460839194653105946532770.356000.000030.00109includedK562U2AF1
SEEXOC6ENSG00000138190.12chr10+946939009469394794688095946881799469406694694187-0.361000.000590.01470excludedK562U2AF1
SEEXOC6ENSG00000138190.12chr10+946955709469564294694066946941879470048394700581-0.152000.000430.03404excludedK562HNRNPL
SEEXOC6ENSG00000138190.12chr10+946939009469394794688095946881799469406694694187-0.564000.000000.00000excludedK562U2AF2
SEEXOC6ENSG00000138190.12chr10+9469557094695642946940669469418794700483947005810.153000.000780.03126includedK562HNRNPU
SEEXOC6ENSG00000138190.12chr10+946955709469564294694066946941879470048394700581-0.107000.001960.04560excludedK562RBM15
SEEXOC6ENSG00000138190.12chr10+946797389467980794675514946756709468809594688179-0.149000.001650.03997excludedK562RBM15
SEEXOC6ENSG00000138190.12chr10+946797389467980794675514946756709468809594688179-0.194000.000320.01144excludedK562AGGF1
A3SSEXOC6ENSG00000138190.12chr10+9465453194654598946545509465459894653086946532770.069000.000050.00049longerK562AQR
A3SSEXOC6ENSG00000138190.12chr10+9465308694653277946531059465327794594466945945810.158000.000030.00032longerK562AQR
MXEEXOC6ENSG00000138190.12chr10+9469390094693947946940669469418794688095946881799469557094695642-0.346000.000110.002602includedK562U2AF2
MXEEXOC6ENSG00000138190.12chr10+94695570946956429470048394700581946940669469418794708030947081360.171000.000570.034081includedHepG2DROSHA

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for EXOC6 is not avaliable on ENCORE database.