EPC2

General Information

Gene Name       : EPC2
Gene ID             : ENSG00000135999.11
Essential Gene : No

Functions

Localization

Domains (AlphaFold: EPC2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878EPC2ENSG00000135999.1111.699.2710.48ENCSR000AEF
HepG2EPC2ENSG00000135999.1112.1916.9314.56ENCSR985KAT
K562EPC2ENSG00000135999.1120.2119.5919.90ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for EPC2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • EPC2 RNA is bound by 26 proteins.  







eCLIP assay for EPC2 is not avaliable on ENCORE database.





26 proteins are bound to EPC2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr2149449646149449691+3'-UTR,intron-Distal4.854637.27557K562TIA1
chr2149449892149449939+3'-UTR,intron-Distal3.903383.31110K562TIA1
chr2149449410149449456+3'-UTR,intron-Distal5.688108.68064HepG2QKI
chr2149449882149449965+3'-UTR,intron-Distal3.436117.63643K562CPSF6
chr2149449679149449875+3'-UTR,intron-Distal3.904406.24904HepG2PTBP1
chr2149449993149450096+3'-UTR,intron-Distal3.933173.88679HepG2CSTF2
chr2149449463149449518+3'-UTR,intron-Distal4.9217415.38642K562QKI
chr2149544861149544905+3'-UTR4.581227.91848K562PUM2
chr2149449737149449760+3'-UTR,intron-Distal3.717393.21228K562TIA1
chr2149449468149449515+3'-UTR,intron-Distal5.689849.73701HepG2QKI
chr2149449715149449837+3'-UTR,intron-Distal4.592619.44715HepG2QKI
chr2149450010149450099+3'-UTR,intron-Distal3.168086.37203K562CSTF2T
chr2149544059149544148+3'-UTR6.6439918.46184K562PUM2
chr2149449406149449463+3'-UTR,CDS,intron-Distal4.4705212.23841K562QKI
chr2149449703149449795+3'-UTR,intron-Distal5.022218.50955K562QKI
chr2149449798149449860+3'-UTR,intron-Distal4.063604.67922K562PTBP1
chr2149447781149447905+5'-UTR,CDS,intron-Proximal4.042727.94477HepG2GRWD1
chr2149402991149403041+5'-UTR,intron-Distal4.462094.31871HepG2HNRNPM
chr2149447841149447936+5'-UTR,CDS4.1107810.22171K562UCHL5
chr2149501270149501341+CDS,intron-Proximal4.4496810.68105HepG2BCLAF1
chr2149447850149447906+CDS4.204307.09561HepG2BCLAF1
chr2149528466149528505+CDS3.138083.94979HepG2BCLAF1
chr2149519411149519501+CDS,intron-Proximal5.698869.32793HepG2BCLAF1
chr2149520238149520298+CDS,intron-Proximal5.305357.04013HepG2BCLAF1
chr2149528403149528466+CDS3.411824.85828HepG2BCLAF1
chr2149522624149522664+CDS3.469143.87469HepG2BCLAF1
chr2149526719149526747+CDS,intron-Proximal3.570614.17155HepG2BCLAF1
chr2149528365149528502+CDS3.111823.21309HepG2GRWD1
chr2149526747149526806+CDS4.980335.23259HepG2BCLAF1
chr2149528347149528409+CDS,intron-Proximal3.390595.94782HepG2U2AF2
chr2149542365149542495+CDS3.877543.08128K562IGF2BP1
chr2149511494149511520+CDS,intron-Proximal4.756604.34038HepG2BCLAF1
chr2149528349149528401+CDS,intron-Proximal4.003713.56076K562BUD13
chr2149522537149522584+CDS3.135433.18789HepG2BCLAF1
chr2149526800149526861+CDS,intron-Proximal4.831155.65342K562AQR
chr2149458324149458364+intron-Distal3.606373.18845HepG2HNRNPM
chr2149485040149485092+intron-Distal4.706453.83958HepG2QKI
chr2149473530149473575+intron-Distal4.683845.76685K562EXOSC5
chr2149475696149475749+intron-Distal3.911415.13840HepG2MATR3
chr2149403740149403911+intron-Distal3.022556.89326K562KHSRP
chr2149402414149402478+intron-Distal4.788156.92570HepG2NCBP2
chr2149475300149475344+intron-Distal4.838505.44508K562EXOSC5
chr2149436772149436874+intron-Distal3.477876.09178HepG2QKI
chr2149458324149458364+intron-Distal3.325704.33009HepG2SUGP2
chr2149415454149415521+intron-Distal3.923173.46495K562TARDBP
chr2149427442149427549+intron-Distal4.195194.50495HepG2ILF3
chr2149473637149473669+intron-Distal4.118213.59917K562EXOSC5
chr2149469953149470028+intron-Distal4.810007.24177K562CSTF2T
chr2149475875149475926+intron-Distal3.053573.64715K562EXOSC5
chr2149473716149473748+intron-Distal4.214543.89080K562EXOSC5
chr2149475877149475952+intron-Distal4.944714.12480HepG2HNRNPM
chr2149432420149432487+intron-Distal3.629454.08043K562HNRNPM
chr2149406407149406567+intron-Distal4.168324.18579K562MATR3
chr2149475072149475152+intron-Distal4.775754.60209HepG2MATR3
chr2149410566149410660+intron-Distal4.737185.79092K562TARDBP
chr2149431786149431858+intron-Distal3.847526.73852HepG2SUGP2
chr2149473587149473637+intron-Distal4.465794.80466K562EXOSC5
chr2149475147149475185+intron-Distal4.500984.80399K562EXOSC5
chr2149430718149430792+intron-Distal4.139243.24322HepG2MATR3
chr2149430430149430473+intron-Distal3.685053.04224HepG2SUGP2
chr2149541730149541810+intron-Distal3.278593.59771HepG2QKI
chr2149475691149475752+intron-Distal4.450789.69330K562EXOSC5
chr2149420423149420492+intron-Distal4.278275.91192HepG2CSTF2
chr2149402414149402500+intron-Distal4.070676.59266K562DROSHA
chr2149475304149475358+intron-Distal3.397454.28420HepG2HNRNPM
chr2149475691149475753+intron-Distal3.025974.77524HepG2SUGP2
chr2149476730149476795+intron-Distal3.494044.14346HepG2SUGP2
chr2149504941149505038+intron-Distal4.685564.40618K562PTBP1
chr2149402760149402841+intron-Distal,intron-Proximal3.630063.47089HepG2TIAL1
chr2149484972149485040+intron-Distal4.324257.08005HepG2QKI
chr2149451508149451543+intron-Distal3.958653.27946HepG2HNRNPM
chr2149458331149458378+intron-Distal4.351264.31720HepG2MATR3
chr2149475294149475347+intron-Distal5.229537.91259HepG2MATR3
chr2149403250149403432+intron-Distal4.3915810.95159K562HNRNPM
chr2149541908149541970+intron-Distal4.550285.58765HepG2QKI
chr2149474192149474253+intron-Distal3.352893.18845HepG2HNRNPM
chr2149477334149477388+intron-Distal4.101503.79098HepG2SUGP2
chr2149474136149474192+intron-Distal5.182388.60156HepG2HNRNPM
chr2149431918149431975+intron-Distal3.430984.81844HepG2SUGP2
chr2149476515149476588+intron-Distal3.309764.53157HepG2MATR3
chr2149504699149504925+intron-Distal3.576525.08047HepG2QKI
chr2149474780149474830+intron-Distal5.167987.38693K562EXOSC5
chr2149432382149432485+intron-Distal4.062916.64193HepG2HNRNPM
chr2149425888149425980+intron-Distal3.775063.25538K562KHSRP
chr2149402410149402503+intron-Distal4.026697.39702K562RBM15
chr2149402790149402856+intron-Distal,intron-Proximal3.894726.90098K562TIA1
chr2149476795149476858+intron-Distal4.809027.59209HepG2SUGP2
chr2149492517149492673+intron-Distal3.739363.06150K562KHSRP
chr2149402411149402503+intron-Distal3.285226.80450K562UCHL5
chr2149458847149458946+intron-Distal3.602144.61500HepG2HNRNPM
chr2149432009149432129+intron-Distal5.059159.09007HepG2SUGP2
chr2149428655149428811+intron-Distal3.629147.82071K562KHSRP
chr2149469815149469893+intron-Distal3.924803.22972K562TARDBP
chr2149474844149474910+intron-Distal4.712134.64592HepG2HNRNPM
chr2149476813149476841+intron-Distal3.328503.10961HepG2MATR3
chr2149474681149474730+intron-Distal4.696275.12361K562EXOSC5
chr2149474783149474823+intron-Distal4.208003.27829HepG2MATR3
chr2149430743149430803+intron-Distal3.016543.10883HepG2SUGP2
chr2149451243149451358+intron-Distal5.585959.03229HepG2QKI
chr2149408144149408229+intron-Distal4.515646.27552K562KHSRP
chr2149403849149403895+intron-Distal3.947883.19904K562TIA1
chr2149475875149475922+intron-Distal4.431734.66737HepG2MATR3
chr2149469951149470043+intron-Distal5.6750216.21877HepG2CSTF2
chr2149428239149428316+intron-Distal3.620967.26220HepG2PCBP2
chr2149475156149475191+intron-Distal4.309664.12480HepG2HNRNPM
chr2149477027149477060+intron-Distal4.875495.72657HepG2MATR3
chr2149402313149402392+intron-Distal3.785958.12220HepG2NCBP2
chr2149458530149458633+intron-Distal3.923783.42844K562KHSRP
chr2149451212149451289+intron-Distal4.600096.05753HepG2SUGP2
chr2149420425149420487+intron-Distal4.158353.80314K562CSTF2T
chr2149475304149475369+intron-Distal3.708465.79523HepG2SUGP2
chr2149403367149403420+intron-Distal5.1750616.59560HepG2HNRNPM
chr2149503835149503965+intron-Distal4.249323.83958HepG2QKI
chr2149459543149459574+intron-Distal3.724053.04224HepG2SUGP2
chr2149419122149419220+intron-Distal3.008634.14287K562KHSRP
chr2149474678149474728+intron-Distal4.328503.96879HepG2MATR3
chr2149504954149505038+intron-Distal3.517416.10762HepG2PTBP1
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for EPC2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for EPC2 is not available on ENCORE database.

  • 77 RBPs can affect the levels of EPC2.  








The Knockdown/knockout RNA-Seq assay for EPC2 is not available on ENCORE database.





77 RBPs can affect the gene expression of EPC2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
EPC2ENSG00000135999.71102.87610780.010900.499603.990903.05500HepG2ASCC1
EPC2ENSG00000135999.71077.99420833.422300.371103.052201.57440HepG2ATP5C1
EPC2ENSG00000135999.7429.13960613.16810-0.514802.547101.65040HepG2BCCIP
EPC2ENSG00000135999.7941.716001248.58530-0.406902.315501.43170HepG2CCAR1
EPC2ENSG00000135999.7761.56760607.917000.325003.109402.41360HepG2CKAP4
EPC2ENSG00000135999.7925.93980754.839200.294602.256601.66640HepG2CELF1
EPC2ENSG00000135999.7768.67270581.736900.401903.845803.07230HepG2DKC1
EPC2ENSG00000135999.7810.96780628.378700.367902.129601.32090HepG2EEF2
EPC2ENSG00000135999.7692.56530510.070700.441202.824401.91340HepG2EIF3D
EPC2ENSG00000135999.7767.69240583.381100.396003.127701.98320HepG2EIF3G
EPC2ENSG00000135999.71300.56960802.384000.696704.493503.62790HepG2EIF4B
EPC2ENSG00000135999.71089.41750800.750800.444005.031903.95790HepG2EIF4G1
EPC2ENSG00000135999.71285.61640767.093500.744908.862807.43960HepG2EIF4G2
EPC2ENSG00000135999.71814.946801211.867900.5826011.8593010.75530HepG2ETF1
EPC2ENSG00000135999.71053.21350818.831700.363102.361601.54280HepG2G3BP2
EPC2ENSG00000135999.7626.60780454.142300.464302.902501.98180HepG2GEMIN5
EPC2ENSG00000135999.7889.434701158.23050-0.381002.350501.75680HepG2GPKOW
EPC2ENSG00000135999.71039.74000784.065900.407102.855302.17100HepG2IGF2BP2
EPC2ENSG00000135999.71756.181201318.201200.413802.562701.76490HepG2LARP4
EPC2ENSG00000135999.7835.12660533.811800.645603.199602.06780HepG2METAP2
EPC2ENSG00000135999.7809.55990631.956000.357203.013702.13400HepG2PARN
EPC2ENSG00000135999.71038.29070701.868000.564803.363702.22010HepG2PCBP2
EPC2ENSG00000135999.71250.16200815.606300.6161012.4324011.36670HepG2PUM1
EPC2ENSG00000135999.71036.67560815.043900.346902.650801.99450HepG2PUM2
EPC2ENSG00000135999.7900.87220619.335800.540507.820406.87210HepG2PUS1
EPC2ENSG00000135999.7967.29570677.402600.513802.310501.66250HepG2RAVER1
EPC2ENSG00000135999.71467.970801012.899300.535208.132807.35370HepG2RBM22
EPC2ENSG00000135999.7907.95760669.465900.439503.438102.32750HepG2RBM27
EPC2ENSG00000135999.71155.53170904.057200.354002.653701.98140HepG2RPLP0
EPC2ENSG00000135999.7685.41830496.355200.465503.544702.85770HepG2RPS19
EPC2ENSG00000135999.7859.13470617.443300.476503.742402.81610HepG2RPS2
EPC2ENSG00000135999.7834.26960632.723700.398801.979801.30330HepG2RPS3A
EPC2ENSG00000135999.7697.43530460.161000.599804.414503.44660HepG2RRP9
EPC2ENSG00000135999.71576.510901007.537200.645804.666703.77750HepG2SF3A3
EPC2ENSG00000135999.71515.785001094.068700.470304.480303.59930HepG2SF3B1
EPC2ENSG00000135999.71657.568101217.335000.445202.367201.64670HepG2SNRNP70
EPC2ENSG00000135999.71079.82610902.263500.259102.248901.81110HepG2SRSF1
EPC2ENSG00000135999.71847.050101177.155900.649804.096402.85300HepG2SRSF3
EPC2ENSG00000135999.71141.57950758.590400.589509.099008.05210HepG2SRSF5
EPC2ENSG00000135999.7889.96230734.036900.277802.501401.97060HepG2SRSF9
EPC2ENSG00000135999.71213.99550993.300200.289403.223702.67990HepG2SSB
EPC2ENSG00000135999.7392.37020629.67510-0.682406.285304.90510HepG2SUPT6H
EPC2ENSG00000135999.7876.82290600.162200.546804.105003.30510HepG2SUPV3L1
EPC2ENSG00000135999.7499.43070625.87060-0.325602.236901.71920HepG2TRIM56
EPC2ENSG00000135999.71001.71480750.578600.416303.377302.40260HepG2TUFM
EPC2ENSG00000135999.71671.67140797.582401.0675012.2060010.85650HepG2U2AF1
EPC2ENSG00000135999.7245.10330354.55810-0.532602.649401.90740HepG2UCHL5
EPC2ENSG00000135999.7968.73730665.979400.540503.015701.69440HepG2XRCC5
EPC2ENSG00000135999.7991.75550676.633900.551503.570102.08390HepG2ZRANB2
EPC2ENSG00000135999.72421.324501133.286701.0952023.1140021.60280K562AQR
EPC2ENSG00000135999.71362.103701109.799300.295402.803201.88410K562ATP5C1
EPC2ENSG00000135999.71850.118001241.280800.575703.150102.00640K562CNOT7
EPC2ENSG00000135999.72570.835201782.193000.528507.561805.97720K562CELF1
EPC2ENSG00000135999.72241.848801297.818800.7885022.8704021.18300K562DDX47
EPC2ENSG00000135999.7646.33120391.853100.721903.980102.74930K562EIF3A
EPC2ENSG00000135999.7870.05900618.022100.493402.879301.82360K562EIF3D
EPC2ENSG00000135999.7815.54680660.234900.304702.426701.67940K562EIF3G
EPC2ENSG00000135999.72400.335501449.838600.7272018.5472016.26840K562EIF4G2
EPC2ENSG00000135999.7836.272701187.20090-0.505503.781802.78060K562FIP1L1
EPC2ENSG00000135999.7738.58610541.871700.446702.869801.72100K562FKBP4
EPC2ENSG00000135999.71473.293201165.043000.338602.510601.69640K562FMR1
EPC2ENSG00000135999.71363.58400987.558600.465403.365102.34950K562FTO
EPC2ENSG00000135999.7795.94720629.108400.339302.447401.87160K562FXR1
EPC2ENSG00000135999.71095.51430705.155200.635504.805003.81440K562G3BP2
EPC2ENSG00000135999.71093.49150624.004000.8092011.4942010.35010K562HNRNPC
EPC2ENSG00000135999.7730.45570557.271300.390302.691301.56910K562HNRNPF
EPC2ENSG00000135999.71361.535901122.547200.278402.004901.31120K562KIF1C
EPC2ENSG00000135999.71245.66770933.463900.416202.349901.49840K562KRR1
EPC2ENSG00000135999.71356.65520881.436500.622004.728903.47820K562NAA15
EPC2ENSG00000135999.71423.94510864.084100.720503.350202.23050K562PABPN1
EPC2ENSG00000135999.71200.82090848.478500.501003.907502.91870K562PCBP3
EPC2ENSG00000135999.7807.68800650.829800.311402.290801.56190K562POLR2G
EPC2ENSG00000135999.7921.049201347.59840-0.549003.944102.94070K562PPIG
EPC2ENSG00000135999.71035.10420561.493400.882306.057004.94730K562PRPF8
EPC2ENSG00000135999.72170.362501581.947800.456105.236804.11670K562PUF60
EPC2ENSG00000135999.72065.588401682.192500.296103.054001.92990K562PUM1
EPC2ENSG00000135999.71743.512301049.039900.732809.597208.63490K562PUS1
EPC2ENSG00000135999.71100.14460672.870600.709204.305502.47480K562RAVER1
EPC2ENSG00000135999.71324.281001022.081400.373603.954703.26130K562RBM15
EPC2ENSG00000135999.7822.74510572.101800.524102.426301.66280K562RPS19
EPC2ENSG00000135999.71684.310201107.379900.604903.816001.94630K562RPS3A
EPC2ENSG00000135999.7836.78740574.275000.543003.548402.02540K562RRP9
EPC2ENSG00000135999.71416.444901039.735000.446002.516601.59050K562SF3B1
EPC2ENSG00000135999.71519.24980907.538500.743203.237401.87100K562SNRNP200
EPC2ENSG00000135999.71274.85250990.237600.364404.841303.64490K562SRPK2
EPC2ENSG00000135999.7998.46270652.774600.613007.707106.32620K562SYNCRIP
EPC2ENSG00000135999.7888.41260706.175200.331102.682701.89140K562U2AF2
EPC2ENSG00000135999.71268.01650924.210600.456207.196705.89210K562WDR43
EPC2ENSG00000135999.71700.172001342.703700.340403.110201.73290K562WRN
EPC2ENSG00000135999.71550.606301276.701000.280302.060801.32770K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for EPC2 is not available on ENCORE database.





3 RBPs can affect the splicing of EPC2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEEPC2ENSG00000135999.7chr2+1495255901495258221495225231495227151495267191495268090.120000.000690.00898includedK562AQR
SEEPC2ENSG00000135999.7chr2+149525590149525655149522523149522715149526719149526809-0.064000.000160.03564excludedK562EIF4G2
SEEPC2ENSG00000135999.7chr2+149525590149525794149522523149522715149526719149526809-0.071000.007220.09183excludedK562HNRNPC

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for EPC2 is not avaliable on ENCORE database.