EDEM2

General Information

Gene Name       : EDEM2
Gene ID             : ENSG00000088298.12
Essential Gene : No

Functions

Localization

Domains (AlphaFold: EDEM2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878EDEM2ENSG00000088298.128.3910.279.33ENCSR000AEF
HepG2EDEM2ENSG00000088298.1237.3235.9836.65ENCSR985KAT
K562EDEM2ENSG00000088298.127.427.417.42ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for EDEM2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • EDEM2 RNA is bound by 19 proteins.  







eCLIP assay for EDEM2 is not avaliable on ENCORE database.





19 proteins are bound to EDEM2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr203373472033734789-3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal5.021564.65563K562AQR
chr203373472233734804-3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal4.171316.92290HepG2AQR
chr203373500333735058-5'-UTR,CDS,intron-Distal4.7220812.43092HepG2DDX3X
chr203373506933735128-5'-UTR,intron-Distal,intron-Proximal4.8565210.30616HepG2DDX3X
chr203373495733735003-5'-UTR,CDS,intron-Distal4.241788.97908HepG2DDX3X
chr203373496833735047-5'-UTR,CDS,intron-Distal4.439346.05571HepG2RPS3
chr203373488133734980-5'-UTR,CDS,intron-Distal4.205907.85990HepG2PRPF8
chr203373491833734992-5'-UTR,CDS,intron-Distal3.876003.67894HepG2AQR
chr203372255533722668-5'-UTR,CDS,intron-Distal3.344326.23251HepG2SND1
chr203386592533865973-5'-UTR,intron-Distal,intron-Proximal4.621897.61488HepG2EFTUD2
chr203371405333714104-CDS,intron-Distal,intron-Proximal4.460153.19000HepG2SND1
chr203370328933703358-CDS,intron-Distal3.452184.37103HepG2SND1
chr203370644333706523-CDS,intron-Distal,intron-Proximal4.196113.23259HepG2LIN28B
chr203370346733703550-CDS,intron-Distal3.963123.57831HepG2SND1
chr203370335633703410-CDS,intron-Distal4.223774.01795HepG2LARP4
chr203386574333865815-intron-Distal,intron-Proximal6.225118.50915HepG2EFTUD2
chr203386569133865801-intron-Distal,intron-Proximal4.261124.96173HepG2U2AF1
chr203385889333859028-intron-Distal3.111373.47356HepG2HNRNPK
chr203385963533859735-intron-Distal,intron-Proximal4.185953.97489K562TIA1
chr203386538533865481-intron-Distal4.5357012.48637HepG2DDX59
chr203386522133865266-intron-Distal4.184514.07750HepG2HNRNPK
chr203386572933865791-intron-Distal,intron-Proximal3.5382111.79280HepG2SF3B4
chr203386518633865243-intron-Distal,intron-Proximal4.063656.92152K562PABPC4
chr203386518933865283-intron-Distal,intron-Proximal3.328593.92922HepG2AKAP1
chr203386601433866102-intron-Distal,intron-Proximal3.5264614.45403HepG2EFTUD2
chr203386538533865462-intron-Distal3.391495.44142HepG2PCBP2
chr203386540233865510-intron-Distal4.1036820.03744K562PCBP1
chr203386570233865732-intron-Distal4.106603.94390HepG2EFTUD2
chr203386593233865990-intron-Distal,intron-Proximal4.018976.72825HepG2XRN2
chr203386577933865841-intron-Distal,intron-Proximal4.469724.69805HepG2NKRF
chr203386595233866039-intron-Distal,intron-Proximal3.107183.56282HepG2AKAP1
chr203386520233865276-intron-Distal5.6687514.58801K562PCBP1
chr203386537133865461-intron-Distal3.484046.19671HepG2HNRNPK
chr203386521433865266-intron-Distal3.401666.64741HepG2DDX59
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for EDEM2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for EDEM2 is not available on ENCORE database.

  • 79 RBPs can affect the levels of EDEM2.  








The Knockdown/knockout RNA-Seq assay for EDEM2 is not available on ENCORE database.





79 RBPs can affect the gene expression of EDEM2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
EDEM2ENSG00000088298.81097.22010848.921600.370002.875501.78600HepG2AATF
EDEM2ENSG00000088298.81483.362201198.231400.307904.045003.33560HepG2ACO1
EDEM2ENSG00000088298.8692.58970956.22460-0.465303.660402.53330HepG2ADAR
EDEM2ENSG00000088298.83590.769201398.359901.3605025.7818024.34850HepG2AKAP1
EDEM2ENSG00000088298.8838.627801156.97990-0.464303.560402.67220HepG2ASCC1
EDEM2ENSG00000088298.81790.086601099.225300.703408.572907.27200HepG2CIRBP
EDEM2ENSG00000088298.81032.78430594.054600.797809.409408.21390HepG2CPSF6
EDEM2ENSG00000088298.8442.46530625.76410-0.500103.958102.69770HepG2CSTF2
EDEM2ENSG00000088298.82017.312401603.445200.331204.795403.99230HepG2CELF1
EDEM2ENSG00000088298.8747.63040981.96940-0.393403.081101.86520HepG2DDX1
EDEM2ENSG00000088298.81683.712501339.425200.329902.145601.58800HepG2DDX3X
EDEM2ENSG00000088298.81674.60420996.336900.749006.949005.79160HepG2DDX55
EDEM2ENSG00000088298.81647.203301150.824300.517304.119503.37720HepG2DDX6
EDEM2ENSG00000088298.8944.326001146.35450-0.279702.711202.03980HepG2DKC1
EDEM2ENSG00000088298.81046.87430707.309800.565605.087303.58430HepG2EFTUD2
EDEM2ENSG00000088298.81411.963401106.086700.352102.313801.76770HepG2EIF2S1
EDEM2ENSG00000088298.8690.83290884.43160-0.356402.786001.70020HepG2EIF3G
EDEM2ENSG00000088298.8790.536301190.23840-0.590303.922303.10870HepG2EIF4B
EDEM2ENSG00000088298.82021.026901629.302100.310702.599401.80860HepG2EIF4G2
EDEM2ENSG00000088298.8593.26320872.54400-0.556602.404101.38530HepG2ESF1
EDEM2ENSG00000088298.81131.447001737.02700-0.6185013.3137012.15870HepG2ETF1
EDEM2ENSG00000088298.8818.91750615.659200.411503.597202.24640HepG2FAM120A
EDEM2ENSG00000088298.8146.58060863.91940-2.5592068.1267064.77630HepG2FUBP3
EDEM2ENSG00000088298.81485.113901013.561100.551003.646502.36720HepG2FUS
EDEM2ENSG00000088298.8488.12470673.38330-0.464202.760802.11980HepG2GPKOW
EDEM2ENSG00000088298.8966.034501143.90160-0.243802.242501.35750HepG2HDGF
EDEM2ENSG00000088298.8516.19410972.10610-0.9132012.3552011.14900HepG2HNRNPA1
EDEM2ENSG00000088298.82065.139101584.370900.382204.525403.38010HepG2HNRNPA2B1
EDEM2ENSG00000088298.81045.117901253.24340-0.262002.743202.02840HepG2HNRNPF
EDEM2ENSG00000088298.8689.239901074.13260-0.6401011.128709.98170HepG2HNRNPU
EDEM2ENSG00000088298.81037.173401234.08080-0.250801.986701.36580HepG2IGF2BP1
EDEM2ENSG00000088298.81266.225401097.192200.206602.229401.56360HepG2ILF2
EDEM2ENSG00000088298.8936.586801095.26570-0.225802.222801.30640HepG2KIF1C
EDEM2ENSG00000088298.81245.78960946.317100.396603.069701.87290HepG2LARP7
EDEM2ENSG00000088298.81626.827701240.812900.390702.577401.96640HepG2MATR3
EDEM2ENSG00000088298.81113.36950720.839100.627103.697702.48720HepG2METAP2
EDEM2ENSG00000088298.81175.00590822.889300.513803.095102.24170HepG2MSI2
EDEM2ENSG00000088298.8401.38820569.82660-0.505503.078202.29040HepG2NSUN2
EDEM2ENSG00000088298.81498.076001130.811600.405702.970602.22490HepG2PABPC4
EDEM2ENSG00000088298.8930.170501173.25570-0.335003.805203.11710HepG2PCBP1
EDEM2ENSG00000088298.81712.953201193.827800.520809.675208.77420HepG2PTBP1
EDEM2ENSG00000088298.81220.128201730.99530-0.504606.509305.49630HepG2PUM2
EDEM2ENSG00000088298.8957.119501292.95290-0.433904.992704.19090HepG2QKI
EDEM2ENSG00000088298.8818.332201173.43490-0.520005.717604.78010HepG2RBM25
EDEM2ENSG00000088298.8268.25500740.27670-1.464505.689603.20680HepG2RBM39
EDEM2ENSG00000088298.81016.246401237.42230-0.284102.874402.24790HepG2RECQL
EDEM2ENSG00000088298.8856.736001350.14260-0.656208.210907.13300HepG2RPLP0
EDEM2ENSG00000088298.81400.18040956.567000.5496010.855609.71050HepG2SAFB2
EDEM2ENSG00000088298.8470.43120714.36820-0.602703.181901.51490HepG2SBDS
EDEM2ENSG00000088298.8858.84550672.635900.352502.253901.40130HepG2SERBP1
EDEM2ENSG00000088298.8976.207601242.93550-0.348504.049803.35650HepG2SF3B4
EDEM2ENSG00000088298.81226.694401564.82900-0.351203.007902.27980HepG2SLBP
EDEM2ENSG00000088298.81343.950401115.526100.268703.463202.75620HepG2SMN1
EDEM2ENSG00000088298.81022.13260707.730200.530202.810402.02390HepG2SNRNP70
EDEM2ENSG00000088298.8797.181301231.29160-0.6272011.6770010.41740HepG2SRSF7
EDEM2ENSG00000088298.8869.078301055.46330-0.280302.821302.26520HepG2SRSF9
EDEM2ENSG00000088298.8477.61410653.90970-0.453202.464801.43560HepG2STIP1
EDEM2ENSG00000088298.81296.981101832.36720-0.498608.815907.81130HepG2SUCLG1
EDEM2ENSG00000088298.81070.77410686.544500.641105.316804.03280HepG2SUPT6H
EDEM2ENSG00000088298.8854.67930626.422900.448103.327302.53970HepG2TARDBP
EDEM2ENSG00000088298.8757.795401043.74830-0.461904.982204.35160HepG2TIAL1
EDEM2ENSG00000088298.81307.755201053.048800.312403.740103.10620HepG2TRIM56
EDEM2ENSG00000088298.81222.907101594.34800-0.382703.512102.51510HepG2TUFM
EDEM2ENSG00000088298.8592.18100870.02200-0.555002.334901.75340HepG2U2AF1
EDEM2ENSG00000088298.8455.10230846.96370-0.896102.487501.55840HepG2U2AF2
EDEM2ENSG00000088298.8431.31190585.80530-0.441702.945902.16560HepG2UCHL5
EDEM2ENSG00000088298.81232.48260855.280600.527008.847707.71820HepG2UPF1
EDEM2ENSG00000088298.8724.77080976.27790-0.429803.412902.61310HepG2XRN2
EDEM2ENSG00000088298.81254.70070940.645500.415506.806806.04820HepG2ZNF622
EDEM2ENSG00000088298.8451.95380335.939700.427902.685601.72200K562AKAP8
EDEM2ENSG00000088298.8511.29240365.319800.484903.745202.34610K562CCDC124
EDEM2ENSG00000088298.8156.4400078.565100.993504.469403.47380K562CPSF6
EDEM2ENSG00000088298.8321.47640431.63470-0.425102.646201.69230K562CELF1
EDEM2ENSG00000088298.8288.44550176.262000.710504.615703.21970K562DDX3X
EDEM2ENSG00000088298.883.87160137.61260-0.714402.635401.34240K562DHX30
EDEM2ENSG00000088298.8470.41710206.593001.1870016.0215014.50450K562EIF2S2
EDEM2ENSG00000088298.8355.77980184.147400.950007.984406.58800K562EIF4A3
EDEM2ENSG00000088298.8202.16620136.605900.565402.421201.62810K562FIP1L1
EDEM2ENSG00000088298.889.13320145.05340-0.702502.309501.67140K562G3BP2
EDEM2ENSG00000088298.8408.30620275.292000.568603.303002.47980K562GRSF1
EDEM2ENSG00000088298.8436.93270185.182201.2384012.8572011.18020K562HSPD1
EDEM2ENSG00000088298.8304.82270219.576600.473102.540301.73410K562MAGOH
EDEM2ENSG00000088298.8297.66320213.344300.480402.610801.96270K562PTBP1
EDEM2ENSG00000088298.873.31580135.42760-0.885303.672102.19540K562SLBP
EDEM2ENSG00000088298.8299.38030226.710500.401002.170101.52840K562UPF1
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for EDEM2 is not available on ENCORE database.





15 RBPs can affect the splicing of EDEM2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEEDEM2ENSG00000088298.8chr20-337327813373282133730175337302813373462733734738-0.065000.006910.09734excludedHepG2U2AF1
SEEDEM2ENSG00000088298.8chr20-337327813373282133730175337302813373462733734738-0.173000.000000.00014excludedHepG2U2AF2
SEEDEM2ENSG00000088298.8chr20-3370550033705656337031693370373633706400337065220.245000.000110.03046includedK562HNRNPA1
SEEDEM2ENSG00000088298.8chr20-3372190733721958337194443371958633722540337227520.516000.000120.04226includedK562PPIL4
SEEDEM2ENSG00000088298.8chr20-337194443371958633714053337141783373017533730281-0.212000.004240.09303excludedHepG2SF3A3
SEEDEM2ENSG00000088298.8chr20-337219073372195833719430337195863372254033722752-0.126000.000120.02274excludedHepG2RBFOX2
SEEDEM2ENSG00000088298.8chr20-3372190733721958337194303371958633722540337227520.085000.000510.02852includedHepG2PCBP1
SEEDEM2ENSG00000088298.8chr20-337194443371958633714053337141783373017533730281-0.159000.000730.03753excludedHepG2PCBP1
SEEDEM2ENSG00000088298.8chr20-3372190733721958337194443371958633722540337227520.237000.000130.03892includedHepG2FUBP3
SEEDEM2ENSG00000088298.8chr20-3372190733721958337194443371958633722540337227520.354000.002180.03654includedK562HNRNPC
MXEEDEM2ENSG00000088298.8chr20-33711692337118373371405333714178337031693370373633719444337195860.073000.000940.082851includedHepG2KHSRP
MXEEDEM2ENSG00000088298.8chr20-3371944433719586337256823372580833714053337141783373017533730281-0.096000.001450.029252includedHepG2FTO
MXEEDEM2ENSG00000088298.8chr20-33714053337141783371944433719586337116923371183733722540337227520.164000.000320.050011includedHepG2SMNDC1
MXEEDEM2ENSG00000088298.8chr20-3373017533730281337327813373282133719444337195863373462733734738-0.410000.002770.021902includedK562AQR
MXEEDEM2ENSG00000088298.8chr20-33706400337065223371169233711837337031693370373633714053337141780.165000.000030.000401includedHepG2U2AF2
MXEEDEM2ENSG00000088298.8chr20-33714053337141783371943033719586337116923371183733721907337219580.100000.000060.003751includedHepG2PCBP1
MXEEDEM2ENSG00000088298.8chr20-33714053337141783371944433719586337116923371183733721907337219580.075000.002760.073531includedHepG2PCBP1
MXEEDEM2ENSG00000088298.8chr20-3372190733721958337225403372275233719444337195863372568233725808-0.069000.000130.006342includedHepG2PCBP1
MXEEDEM2ENSG00000088298.8chr20-33706400337065223371169233711837337031693370373633714053337141780.124000.000070.002291includedHepG2HNRNPUL1
MXEEDEM2ENSG00000088298.8chr20-3372190733721958337225403372275233719444337195863372568233725808-0.375000.001300.024842includedK562HNRNPC
MXEEDEM2ENSG00000088298.8chr20-3371405333714178337225403372275233711692337118373372568233725808-0.195000.000010.004172includedHepG2DDX52

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for EDEM2 is not avaliable on ENCORE database.