DHDDS

General Information

Gene Name       : DHDDS
Gene ID             : ENSG00000117682.16
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: DHDDS)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878DHDDSENSG00000117682.1631.2725.3128.29ENCSR000AEF
HepG2DHDDSENSG00000117682.1621.9520.5621.25ENCSR985KAT
K562DHDDSENSG00000117682.1630.2033.8032.00ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for DHDDS is not avaliable on ENCORE database.



Proteins bound to RNA
  • DHDDS RNA is bound by 16 proteins.  







eCLIP assay for DHDDS is not avaliable on ENCORE database.





16 proteins are bound to DHDDS RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr12679748526797560+3'-UTR4.137238.62096K562UPF1
chr12679751126797616+3'-UTR4.388065.01722K562CSTF2T
chr12679716426797249+3'-UTR3.906783.46958K562YBX3
chr12679555426795682+3'-UTR,CDS3.663634.22460K562RBM15
chr12677280526772874+5'-UTR,CDS,intron-Distal,intron-Proximal3.737996.41974HepG2PPIG
chr12677276926772868+5'-UTR,CDS,intron-Distal,intron-Proximal4.388896.99120K562AQR
chr12676927326769360+5'-UTR,CDS3.876013.56019HepG2GRWD1
chr12675939426759498+5'-UTR,CDS3.545145.76104HepG2BCLAF1
chr12676917326769267+5'-UTR,CDS,intron-Proximal3.627567.96049HepG2U2AF2
chr12675887126758977+5'-UTR,intron-Distal,intron-Proximal4.216854.61711HepG2NCBP2
chr12676931026769365+5'-UTR,CDS,intron-Proximal3.562483.32039HepG2PPIG
chr12675943526759501+5'-UTR,CDS,intron-Proximal4.161083.53067K562SRSF1
chr12675938126759456+5'-UTR,CDS,intron-Proximal3.615708.28216K562DDX3X
chr12676472026764829+CDS,intron-Proximal3.471345.13777HepG2PRPF8
chr12676861126768735+intron-Distal3.988778.17387K562KHSRP
chr12676882026768883+intron-Distal3.832823.07287K562TIA1
chr12675956026759648+intron-Distal,intron-Proximal3.695456.48117K562KHSRP
chr12677318326773258+intron-Distal4.146903.91772K562TARDBP
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for DHDDS is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for DHDDS is not available on ENCORE database.

  • 77 RBPs can affect the levels of DHDDS.  








The Knockdown/knockout RNA-Seq assay for DHDDS is not available on ENCORE database.





77 RBPs can affect the gene expression of DHDDS :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
DHDDSENSG00000117682.12623.26170433.383900.524105.784604.96830HepG2ACO1
DHDDSENSG00000117682.12848.70230473.031300.843207.381206.55760HepG2AKAP1
DHDDSENSG00000117682.12574.89860435.350700.401003.288602.46050HepG2AKAP8L
DHDDSENSG00000117682.12593.43520409.101500.536503.046002.05950HepG2BCCIP
DHDDSENSG00000117682.12626.56740491.382200.350502.307801.59810HepG2CALR
DHDDSENSG00000117682.12551.27160371.852600.567903.790702.89540HepG2CIRBP
DHDDSENSG00000117682.12949.90770519.345200.8710016.4418015.13600HepG2CELF1
DHDDSENSG00000117682.12566.38730363.002200.641705.173304.27370HepG2DDX21
DHDDSENSG00000117682.12598.09120453.133800.400302.139001.58260HepG2DDX3X
DHDDSENSG00000117682.12716.61550402.228500.833106.872705.71950HepG2DDX55
DHDDSENSG00000117682.12462.92710284.325600.703103.733502.69290HepG2EIF3D
DHDDSENSG00000117682.12644.54100413.538100.640204.490403.67790HepG2EIF4A3
DHDDSENSG00000117682.12570.07580402.625400.501602.391701.75060HepG2EIF4B
DHDDSENSG00000117682.12651.22090785.42610-0.270302.345201.78410HepG2ETF1
DHDDSENSG00000117682.12476.80420345.819300.463302.880001.71460HepG2FASTKD2
DHDDSENSG00000117682.12891.70610648.888100.458502.896302.10850HepG2FIP1L1
DHDDSENSG00000117682.12612.20120417.223600.553103.744502.94900HepG2FXR1
DHDDSENSG00000117682.12471.15180366.426100.362601.907201.35960HepG2HNRNPA1
DHDDSENSG00000117682.12675.59690827.83120-0.293202.371201.70350HepG2HNRNPF
DHDDSENSG00000117682.12580.26100447.728300.374002.381601.49840HepG2HNRNPM
DHDDSENSG00000117682.12593.88280815.18090-0.456904.042603.18140HepG2IGF2BP1
DHDDSENSG00000117682.12607.06210393.427400.625604.500203.65720HepG2IGF2BP2
DHDDSENSG00000117682.12934.92970666.391800.488402.872502.02650HepG2LARP4
DHDDSENSG00000117682.12641.01150419.708200.610904.012903.26520HepG2MATR3
DHDDSENSG00000117682.12570.31490297.582900.938405.469004.02920HepG2METAP2
DHDDSENSG00000117682.12878.74130525.204700.742508.825207.45720HepG2MSI2
DHDDSENSG00000117682.12727.79180429.597200.760406.525905.57110HepG2NCBP2
DHDDSENSG00000117682.12290.69900533.27860-0.875407.649006.44680HepG2NSUN2
DHDDSENSG00000117682.12543.14080382.595900.505403.043102.28820HepG2PABPC4
DHDDSENSG00000117682.12521.08220400.759800.378702.644601.81360HepG2PARN
DHDDSENSG00000117682.12550.56010397.396800.470204.072403.36280HepG2PCBP1
DHDDSENSG00000117682.12475.63610597.68360-0.329502.466101.73080HepG2PRPF4
DHDDSENSG00000117682.12590.67270404.363200.546605.257604.55320HepG2PTBP1
DHDDSENSG00000117682.12399.07990528.56730-0.405402.427001.86310HepG2PUF60
DHDDSENSG00000117682.12680.68860561.107000.278602.443001.87890HepG2PUM1
DHDDSENSG00000117682.12816.82720560.691300.542705.668504.72120HepG2PUM2
DHDDSENSG00000117682.12594.69200383.390600.633202.831402.11910HepG2RAVER1
DHDDSENSG00000117682.12803.26870638.188800.331802.640601.80050HepG2RBM15
DHDDSENSG00000117682.12839.05740656.468700.353903.144002.60090HepG2RBM22
DHDDSENSG00000117682.12549.94580276.647900.9911011.1781010.04300HepG2RPS19
DHDDSENSG00000117682.12562.11540406.785700.466502.670501.61360HepG2RPS5
DHDDSENSG00000117682.12540.12250277.680500.959809.554707.83700HepG2SERBP1
DHDDSENSG00000117682.12921.51440596.268000.627903.996503.17970HepG2SF3A3
DHDDSENSG00000117682.12553.16930420.466500.395602.577601.95310HepG2SMN1
DHDDSENSG00000117682.12550.06190390.882100.492802.519001.60760HepG2SMNDC1
DHDDSENSG00000117682.12903.67630741.453200.285402.384101.90780HepG2SRFBP1
DHDDSENSG00000117682.12861.21130439.430200.9706017.7460016.76600HepG2SRSF1
DHDDSENSG00000117682.12717.57490521.894500.459304.807504.01980HepG2SRSF5
DHDDSENSG00000117682.12611.85090813.30460-0.410604.201703.37090HepG2SRSF7
DHDDSENSG00000117682.12829.57120593.528200.482906.164805.30450HepG2SUCLG1
DHDDSENSG00000117682.12756.29880586.235500.367402.272301.60620HepG2TARDBP
DHDDSENSG00000117682.12784.48470546.614900.521103.438602.50390HepG2UBE2L3
DHDDSENSG00000117682.12336.14690236.542700.506902.653201.91010HepG2UCHL5
DHDDSENSG00000117682.121034.12110510.535401.0182023.6373022.14180HepG2UTP3
DHDDSENSG00000117682.121547.08970581.577801.4114064.4323062.70930HepG2ZNF622
DHDDSENSG00000117682.12640.56060939.43210-0.552507.371106.51000K562AGGF1
DHDDSENSG00000117682.121969.973401244.552300.662408.325307.39610K562AQR
DHDDSENSG00000117682.121095.98480865.191100.341002.218001.44350K562BOP1
DHDDSENSG00000117682.12878.27470633.464000.471303.889402.36020K562CIRBP
DHDDSENSG00000117682.122060.545401751.845300.234102.457201.53950K562CELF1
DHDDSENSG00000117682.122204.322601338.936300.7191019.1201017.55760K562DDX47
DHDDSENSG00000117682.12920.078101105.71990-0.265202.274901.61330K562EIF2S2
DHDDSENSG00000117682.12990.31220546.925300.856405.842604.34510K562EIF3A
DHDDSENSG00000117682.12768.40140553.814800.472404.644903.62600K562EIF3G
DHDDSENSG00000117682.12894.07150524.917500.768209.392707.87500K562EIF4A3
DHDDSENSG00000117682.121275.24800936.001600.446103.813902.80450K562FMR1
DHDDSENSG00000117682.121192.16210545.892301.1268027.8391026.04830K562FXR1
DHDDSENSG00000117682.121484.97660878.364200.7574011.037209.42710K562GPKOW
DHDDSENSG00000117682.121653.61890723.413701.1926027.5051025.70870K562HNRNPC
DHDDSENSG00000117682.121577.614801047.533700.590605.494304.12340K562HNRNPM
DHDDSENSG00000117682.12774.35090981.78980-0.342402.392001.56110K562HNRNPU
DHDDSENSG00000117682.12726.669501037.41940-0.513603.446202.51350K562KIF1C
DHDDSENSG00000117682.12791.25190619.883800.352002.590601.69980K562MATR3
DHDDSENSG00000117682.12774.57350524.159500.563305.747103.98780K562NCBP2
DHDDSENSG00000117682.121491.230201059.009800.493702.749201.52000K562PABPC1
DHDDSENSG00000117682.12993.04880603.525800.718309.950108.74390K562PTBP1
DHDDSENSG00000117682.122322.112701554.924800.578508.226306.81760K562PUF60
DHDDSENSG00000117682.12629.15760969.49540-0.623806.067505.30170K562PUS1
DHDDSENSG00000117682.12718.30700944.56740-0.395103.755203.08000K562RBM15
DHDDSENSG00000117682.12852.26160578.597200.558605.251804.04960K562RBM22
DHDDSENSG00000117682.121233.86680647.500900.9301011.113309.44140K562RPS19
DHDDSENSG00000117682.12905.94510556.801100.702205.548904.06360K562RPS3
DHDDSENSG00000117682.121458.62720888.800200.7146010.459608.43340K562SAFB
DHDDSENSG00000117682.121184.41390918.932600.366002.746301.30890K562SDAD1
DHDDSENSG00000117682.121445.422201155.174800.323303.606102.68270K562SF3A3
DHDDSENSG00000117682.121147.41660591.679600.9554016.6413014.91500K562SRSF1
DHDDSENSG00000117682.121315.541901671.13740-0.345202.772801.41310K562SSRP1
DHDDSENSG00000117682.121440.492401000.547600.525706.991305.66940K562SYNCRIP
DHDDSENSG00000117682.12928.66240598.768700.633106.258905.15620K562TARDBP
DHDDSENSG00000117682.121585.952801241.285900.353404.957704.02640K562UPF1
DHDDSENSG00000117682.121310.443701104.503100.246602.681001.84720K562WDR43
DHDDSENSG00000117682.121078.039701402.16260-0.379203.435502.45670K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for DHDDS is not available on ENCORE database.





5 RBPs can affect the splicing of DHDDS :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEDHDDSENSG00000117682.12chr1+267692212676936426764658267647752677280626772875-0.064000.000750.00958excludedK562AQR
SEDHDDSENSG00000117682.12chr1+2677404926774151267728062677292326784281267843960.216000.000740.05130includedK562HNRNPL
A3SSDHDDSENSG00000117682.12chr1+2676919826769364267692212676936426764618267647750.092000.003250.01975longerK562AQR
A3SSDHDDSENSG00000117682.12chr1+2675930226759499267593812675949926758829267588670.101000.000000.00004longerK562AQR
MXEDHDDSENSG00000117682.12chr1+2677280626772923267740492677415126769221267693642678428126784396-0.073000.009810.086272includedK562DROSHA
MXEDHDDSENSG00000117682.12chr1+26772806267729232678652726786635267646582676477526795385267958640.061000.003410.026071includedK562AQR
MXEDHDDSENSG00000117682.12chr1+2677280626772923267842812678439626769221267693642678652726786635-0.119000.007460.049892includedK562AQR
MXEDHDDSENSG00000117682.12chr1+2676922126769364267728062677292326764658267647752678428126784396-0.127000.009800.062302includedK562AQR
MXEDHDDSENSG00000117682.12chr1+26772806267729232677404926774151267692212676936426784281267843960.202000.000330.027991includedK562TRA2A
MXEDHDDSENSG00000117682.12chr1+2676922126769364267728062677292326764658267647752677404926774151-0.257000.000750.019982includedK562HNRNPUL1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for DHDDS is not avaliable on ENCORE database.