CWC22

General Information

Gene Name       : CWC22
Gene ID             : ENSG00000163510.13
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: CWC22)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878CWC22ENSG00000163510.1332.0626.2129.14ENCSR000AEF
HepG2CWC22ENSG00000163510.1317.5134.4825.99ENCSR985KAT
K562CWC22ENSG00000163510.1332.8136.4734.64ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for CWC22 is not avaliable on ENCORE database.



Proteins bound to RNA
  • CWC22 RNA is bound by 20 proteins.  







eCLIP assay for CWC22 is not avaliable on ENCORE database.





20 proteins are bound to CWC22 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr2180809731180809804-3'-UTR,intron-Distal,intron-Proximal6.4915610.80095K562PUM2
chr2180858050180858102-5'-UTR,CDS,intron-Distal3.577494.41784HepG2GRWD1
chr2180871763180871815-5'-UTR,intron-Distal,intron-Proximal4.965817.02967HepG2PRPF8
chr2180819639180819689-CDS,intron-Distal,intron-Proximal3.768384.49024K562AQR
chr2180829287180829305-CDS,intron-Distal3.980335.36555HepG2BCLAF1
chr2180835404180835514-CDS,intron-Distal3.2729013.67826K562ZNF622
chr2180835394180835490-CDS,intron-Distal4.136818.39611HepG2GRWD1
chr2180829278180829333-CDS,intron-Distal3.144585.17653K562UCHL5
chr2180846526180846541-CDS,intron-Distal3.330634.00731K562UCHL5
chr2180829238180829290-CDS,intron-Distal,intron-Proximal3.405173.54718K562PRPF8
chr2180835391180835484-CDS,intron-Distal3.7030611.06562K562UCHL5
chr2180830620180830688-CDS,intron-Distal3.8362710.53208K562UCHL5
chr2180851398180851429-CDS,intron-Distal,intron-Proximal3.942173.12843K562PRPF8
chr2180846634180846679-CDS,intron-Distal4.021036.40330K562UCHL5
chr2180830616180830694-CDS,intron-Distal3.8029210.01989K562ZNF622
chr2180835392180835458-CDS,intron-Distal3.844369.43524HepG2BCLAF1
chr2180835380180835474-CDS,intron-Distal,intron-Proximal3.038554.83253K562GRWD1
chr2180846499180846553-CDS,intron-Distal3.480305.31167HepG2GRWD1
chr2180809925180809986-CDS,intron-Distal3.738728.81620HepG2BCLAF1
chr2180830600180830707-CDS,intron-Distal,intron-Proximal4.751047.13530K562SRSF1
chr2180823755180823799-CDS,intron-Distal3.763856.06436HepG2BCLAF1
chr2180809902180809967-CDS,intron-Distal4.212114.22893K562RBM15
chr2180846495180846531-CDS,intron-Distal3.397185.65306K562ZNF622
chr2180829290180829312-CDS,intron-Distal3.842093.34184HepG2GRWD1
chr2180823769180823803-CDS,intron-Distal3.227744.81603K562BUD13
chr2180815330180815372-CDS,intron-Distal3.382923.60157HepG2GRWD1
chr2180830655180830684-CDS,intron-Distal3.365155.15776HepG2BCLAF1
chr2180823770180823859-CDS,intron-Distal,intron-Proximal5.281216.40247K562SF3B4
chr2180815326180815378-CDS,intron-Distal3.898438.25234K562ZNF622
chr2180846642180846656-CDS,intron-Distal4.715075.37137HepG2BCLAF1
chr2180835375180835453-CDS,intron-Distal,intron-Proximal3.313733.32039HepG2PPIG
chr2180830604180830696-CDS,intron-Distal,intron-Proximal4.807825.91688K562TRA2A
chr2180818299180818382-intron-Distal3.251183.77649K562LIN28B
chr2180826098180826163-intron-Distal3.003833.65707HepG2KHSRP
chr2180822473180822555-intron-Distal4.832854.64001HepG2U2AF2
chr2180855233180855281-intron-Distal3.497304.08528HepG2SUGP2
chr2180849454180849541-intron-Distal4.949615.61339K562QKI
chr2180842787180842871-intron-Distal,intron-Proximal4.184883.31283K562PRPF8
chr2180856658180856724-intron-Distal3.306913.23296HepG2SUGP2
chr2180855087180855121-intron-Distal3.077093.07751K562KHSRP
chr2180854988180855096-intron-Distal3.308743.29213HepG2KHSRP
chr2180855231180855313-intron-Distal4.8545011.52400K562PTBP1
chr2180828862180828917-intron-Distal3.013153.80334HepG2U2AF2
chr2180820086180820223-intron-Distal3.448844.93120K562KHSRP
chr2180855236180855340-intron-Distal3.773558.88673HepG2PTBP1
chr2180856229180856340-intron-Distal4.203897.32721HepG2MATR3
chr2180849407180849516-intron-Distal3.051185.22328K562KHSRP
chr2180855236180855346-intron-Distal4.415523.27829HepG2MATR3
chr2180829181180829238-intron-Distal,intron-Proximal4.564383.89565K562PRPF8
chr2180831056180831229-intron-Distal3.515645.32884K562KHSRP
chr2180838027180838084-intron-Distal,intron-Proximal3.131913.07751K562KHSRP
chr2180826201180826302-intron-Distal4.562556.51328K562KHSRP
chr2180842477180842564-intron-Distal4.023434.07352K562KHSRP
chr2180849547180849668-intron-Distal3.954684.10688K562KHSRP
chr2180854992180855087-intron-Distal5.6001212.71898K562KHSRP
chr2180826116180826195-intron-Distal3.370884.08064K562KHSRP
chr2180856553180856621-intron-Distal3.955927.54890HepG2SUGP2
chr2180843285180843366-intron-Distal3.739363.06150K562KHSRP
chr2180856193180856341-intron-Distal3.5972710.87910HepG2SUGP2
chr2180856443180856494-intron-Distal3.353994.35402HepG2SUGP2
chr2180835111180835172-intron-Distal,intron-Proximal4.238343.89565K562PRPF8
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for CWC22 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for CWC22 is not available on ENCORE database.

  • 76 RBPs can affect the levels of CWC22.  








The Knockdown/knockout RNA-Seq assay for CWC22 is not available on ENCORE database.





76 RBPs can affect the gene expression of CWC22 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
CWC22ENSG00000163510.91128.280601371.23170-0.281303.041902.32710HepG2AUH
CWC22ENSG00000163510.91228.831701666.73070-0.439704.277303.55180HepG2BOP1
CWC22ENSG00000163510.91153.797601530.14290-0.407303.416902.66090HepG2CPSF6
CWC22ENSG00000163510.9781.977801196.86000-0.6141010.032008.95510HepG2CELF1
CWC22ENSG00000163510.9661.26630857.00890-0.374103.349402.07490HepG2DDX1
CWC22ENSG00000163510.9711.60520880.12270-0.306601.998601.41060HepG2DDX21
CWC22ENSG00000163510.9848.850401330.02610-0.647904.350503.58050HepG2DDX3X
CWC22ENSG00000163510.9767.625701142.27490-0.573403.961303.23270HepG2DDX6
CWC22ENSG00000163510.9658.82350840.37250-0.351102.546801.86780HepG2DNAJC21
CWC22ENSG00000163510.9570.14200832.82610-0.546705.035604.19710HepG2DNAJC2
CWC22ENSG00000163510.9700.134301098.33970-0.649605.052704.26460HepG2EIF2S1
CWC22ENSG00000163510.9822.862901213.91210-0.560903.981803.21930HepG2EIF4A3
CWC22ENSG00000163510.91522.129001269.632000.261602.637601.81710HepG2EIF4G1
CWC22ENSG00000163510.9816.57090652.969200.322502.132601.43450HepG2FUBP3
CWC22ENSG00000163510.9841.173001136.02610-0.433502.862002.18590HepG2G3BP1
CWC22ENSG00000163510.91031.082901734.51800-0.750408.478507.39910HepG2GPKOW
CWC22ENSG00000163510.9592.92240943.67110-0.670407.135206.06150HepG2HNRNPC
CWC22ENSG00000163510.91115.456201655.28410-0.569405.828504.94990HepG2HNRNPLL
CWC22ENSG00000163510.9722.10080937.43520-0.376503.480002.80830HepG2HNRNPU
CWC22ENSG00000163510.9873.402001073.64020-0.297802.239501.58430HepG2IGF2BP1
CWC22ENSG00000163510.9858.366401154.81230-0.428002.768802.09330HepG2IGF2BP2
CWC22ENSG00000163510.91494.948301913.26290-0.355902.067201.35780HepG2LARP4
CWC22ENSG00000163510.9668.788101260.83180-0.914808.723307.63180HepG2NCBP2
CWC22ENSG00000163510.9829.548101103.83910-0.412104.910704.22520HepG2PTBP1
CWC22ENSG00000163510.9944.481301218.19450-0.367203.152902.52330HepG2PUF60
CWC22ENSG00000163510.9708.38640932.55250-0.396604.727703.96360HepG2PUS1
CWC22ENSG00000163510.9992.600401195.42560-0.268202.105101.54850HepG2QKI
CWC22ENSG00000163510.9959.792301315.85630-0.455206.021705.33060HepG2RBM22
CWC22ENSG00000163510.91041.791301228.44380-0.237801.993101.51780HepG2NELFE
CWC22ENSG00000163510.91820.471301256.484600.534803.740002.95150HepG2SF3A3
CWC22ENSG00000163510.9802.78740973.62000-0.278302.050901.48460HepG2SMN1
CWC22ENSG00000163510.91770.715701486.220200.252603.239102.71060HepG2SRFBP1
CWC22ENSG00000163510.91441.947201199.524900.265502.909802.42840HepG2SRSF1
CWC22ENSG00000163510.9869.230201071.17490-0.301402.928602.21590HepG2SRSF7
CWC22ENSG00000163510.9622.93130827.64240-0.409901.977001.39100HepG2SUPV3L1
CWC22ENSG00000163510.91041.156301613.43780-0.632007.666306.53600HepG2TARDBP
CWC22ENSG00000163510.9594.80930911.04990-0.615106.812006.09080HepG2TIAL1
CWC22ENSG00000163510.9635.29610919.02610-0.532705.877205.10950HepG2TRIM56
CWC22ENSG00000163510.91804.127601164.788100.631106.558805.60520HepG2U2AF1
CWC22ENSG00000163510.9921.879501259.66870-0.450403.255602.34800HepG2UBE2L3
CWC22ENSG00000163510.9898.055601114.31110-0.311303.244602.49980HepG2UPF1
CWC22ENSG00000163510.91454.433301166.943000.317602.500601.38450K562AARS
CWC22ENSG00000163510.92049.231601579.369700.375606.125505.33270K562AGGF1
CWC22ENSG00000163510.92059.053801643.412300.325202.925202.25300K562AKAP8L
CWC22ENSG00000163510.93635.161502374.559900.614308.803507.85280K562AQR
CWC22ENSG00000163510.92168.128501724.347600.330304.212703.06160K562ATP5C1
CWC22ENSG00000163510.9956.308301206.68660-0.335503.874502.72470K562BCLAF1
CWC22ENSG00000163510.91892.527602396.41110-0.340602.674101.81700K562BOP1
CWC22ENSG00000163510.91734.240202548.12060-0.555108.706707.29980K562CPSF6
CWC22ENSG00000163510.9734.49430915.45160-0.317702.573101.55970K562CSTF2
CWC22ENSG00000163510.9790.412701086.21180-0.458604.544503.16140K562DDX3X
CWC22ENSG00000163510.92960.581502523.366700.230402.977702.30290K562DDX47
CWC22ENSG00000163510.92403.357701768.388100.442507.606906.02560K562DKC1
CWC22ENSG00000163510.9979.867701193.09740-0.284102.841201.61430K562EIF2S1
CWC22ENSG00000163510.91473.889501819.54380-0.303903.503202.70960K562EIF2S2
CWC22ENSG00000163510.91403.305001134.818500.306302.297101.54730K562EIF4A3
CWC22ENSG00000163510.91639.552202195.45690-0.421202.702901.86430K562FIP1L1
CWC22ENSG00000163510.91974.479602592.55920-0.392903.821002.81010K562FMR1
CWC22ENSG00000163510.91503.189001180.162700.348904.128003.41120K562FXR1
CWC22ENSG00000163510.92173.388901378.348100.656905.742904.64120K562G3BP2
CWC22ENSG00000163510.91806.612002432.86650-0.429403.652002.74460K562GPKOW
CWC22ENSG00000163510.91881.260002424.78850-0.366203.803902.92210K562GRSF1
CWC22ENSG00000163510.9782.379601276.93960-0.706709.699108.63630K562HNRNPC
CWC22ENSG00000163510.92561.596701744.048100.554508.081806.48380K562KIF1C
CWC22ENSG00000163510.92996.092401953.777600.6167010.007408.07460K562MBNL1
CWC22ENSG00000163510.91666.214702374.73300-0.511206.541705.16950K562METAP2
CWC22ENSG00000163510.91485.316301757.19900-0.242502.770601.96080K562MTPAP
CWC22ENSG00000163510.92416.897601369.458700.819506.049804.55490K562NAA15
CWC22ENSG00000163510.91603.684001952.42580-0.283904.771603.82790K562NSUN2
CWC22ENSG00000163510.91746.716301406.863500.312102.540701.60430K562PCBP2
CWC22ENSG00000163510.91251.334801623.26930-0.375402.666801.85250K562PCBP3
CWC22ENSG00000163510.9995.968601245.12400-0.322102.637001.85750K562POLR2G
CWC22ENSG00000163510.91805.349602492.07070-0.465103.216102.31940K562PPIG
CWC22ENSG00000163510.92043.93290976.002001.0663020.1336018.10110K562PRPF8
CWC22ENSG00000163510.9799.982601144.90160-0.517204.634203.41940K562PSIP1
CWC22ENSG00000163510.94255.457503270.064600.379903.907802.94290K562PUF60
CWC22ENSG00000163510.94155.197803477.976600.256602.872601.78440K562PUM1
CWC22ENSG00000163510.93155.257401629.767100.9530018.0854016.73150K562PUS1
CWC22ENSG00000163510.92585.501801588.001400.7031016.2222014.77100K562RBM15
CWC22ENSG00000163510.91809.024801433.413900.335703.572502.59580K562SF3B4
CWC22ENSG00000163510.93697.985802176.613100.764603.868602.32370K562SNRNP200
CWC22ENSG00000163510.9728.74760990.19380-0.442303.593202.38010K562SRFBP1
CWC22ENSG00000163510.91790.579701505.849400.249701.956301.34890K562SRSF1
CWC22ENSG00000163510.91763.761701248.862700.497904.469503.41960K562SYNCRIP
CWC22ENSG00000163510.91161.485601470.15820-0.340003.135202.25520K562TIA1
CWC22ENSG00000163510.9855.564001101.20890-0.364102.362001.50260K562TIAL1
CWC22ENSG00000163510.9827.725701169.84610-0.499104.728403.41280K562TRIM56
CWC22ENSG00000163510.91848.784201336.263300.468303.765802.44940K562U2AF1
CWC22ENSG00000163510.92109.743201380.005000.6123010.578209.00650K562U2AF2
CWC22ENSG00000163510.91697.444402070.19690-0.286404.037703.18510K562UPF1
CWC22ENSG00000163510.92196.409301842.037600.253703.550702.59990K562WDR43
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for CWC22 is not available on ENCORE database.





1 RBPs can affect the splicing of CWC22 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
A3SSCWC22ENSG00000163510.9chr2-1808356671808358721808356671808358031808379191808379730.104000.000000.00000longerK562AQR
A3SSCWC22ENSG00000163510.9chr2-1808580411808582481808580411808581811808717961808718400.168000.000000.00000longerK562AQR
A3SSCWC22ENSG00000163510.9chr2-1808292731808293831808292731808293551808306041808307690.071000.000000.00000longerK562AQR
A3SSCWC22ENSG00000163510.9chr2-1808429161808431281808429161808430451808464781808467240.052000.000000.00001longerK562AQR
A3SSCWC22ENSG00000163510.9chr2-1808155511808157131808155511808156531808171971808173250.246000.000000.00000longerK562AQR
MXECWC22ENSG00000163510.9chr2-1808237481808238091808292731808293831808196831808197611808306041808307090.054000.000000.000031includedK562AQR
MXECWC22ENSG00000163510.9chr2-1808356671808358031808379191808380061808353761808355831808383601808385330.052000.000420.004261includedK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for CWC22 is not avaliable on ENCORE database.