CTU2

General Information

Gene Name       : CTU2
Gene ID             : ENSG00000174177.12
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: CTU2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878CTU2ENSG00000174177.120.943.822.38ENCSR000AEF
HepG2CTU2ENSG00000174177.1220.844.3912.62ENCSR985KAT
K562CTU2ENSG00000174177.1233.8711.8922.88ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for CTU2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • CTU2 RNA is bound by 16 proteins.  







eCLIP assay for CTU2 is not avaliable on ENCORE database.





16 proteins are bound to CTU2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr168878143588781508+3'-UTR,CDS,intron-Distal,intron-Proximal4.685933.74891K562DDX55
chr168877868388778752+3'-UTR,CDS4.545373.79199HepG2PPIG
chr168878105588781136+3'-UTR,CDS3.310193.99124HepG2PPIG
chr168877799288778049+3'-UTR,CDS,intron-Proximal5.8372210.07464K562SF3B4
chr168877809188778155+3'-UTR,CDS,intron-Proximal4.9204011.17766HepG2PRPF8
chr168878091388780997+3'-UTR,CDS,intron-Proximal5.967839.61799HepG2EFTUD2
chr168877809988778176+3'-UTR,CDS,intron-Proximal5.549859.63974K562AQR
chr168878154088781618+3'-UTR,CDS,intron-Proximal3.370984.21476HepG2SF3B4
chr168877925688779311+3'-UTR,CDS3.928716.06308HepG2PPIG
chr168877862688778692+3'-UTR,CDS,intron-Proximal4.694965.59044HepG2SF3B4
chr168878142088781474+3'-UTR,CDS,intron-Distal,intron-Proximal5.246656.41139HepG2EFTUD2
chr168877867288778735+3'-UTR,CDS,intron-Proximal3.614914.97821K562BUD13
chr168877868088778740+3'-UTR,CDS,intron-Proximal3.257614.30677K562YBX3
chr168878139388781469+3'-UTR,CDS,intron-Distal,intron-Proximal4.483345.89229K562EFTUD2
chr168878170688781766+3'-UTR4.444486.24385K562PUM2
chr168877658188776633+5'-UTR,CDS,intron-Proximal4.930434.90235K562SF3B4
chr168877359788773661+5'-UTR,CDS,intron-Proximal3.826588.17589HepG2PRPF8
chr168877290288773007+5'-UTR,CDS,intron-Proximal4.554807.63469K562DDX3X
chr168877859388778666+CDS,intron-Proximal5.287905.90023K562SF3B4
chr168877724688777345+intron-Distal3.656963.15816HepG2PRPF4
chr168877728588777362+intron-Distal3.995603.45219HepG2RBFOX2
chr168877956788779679+intron-Distal,intron-Proximal5.6310511.95366HepG2HNRNPK
chr168877958788779683+intron-Distal,intron-Proximal5.8963211.02063HepG2DDX59
chr168877744288777544+intron-Distal4.323284.43116HepG2RBFOX2
chr168877889788778942+intron-Distal,intron-Proximal3.674823.01266HepG2SF3B4
chr168877755288777597+intron-Distal4.715193.11886K562DROSHA
chr168878091288780992+intron-Proximal3.564344.23616K562TIA1
chr168877657588776629+intron-Proximal4.922258.23487HepG2SF3B4
chr168877933188779401+intron-Proximal4.992298.76047HepG2HNRNPK
chr168878018688780231+intron-Proximal4.747594.13847K562AQR
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for CTU2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for CTU2 is not available on ENCORE database.

  • 88 RBPs can affect the levels of CTU2.  








The Knockdown/knockout RNA-Seq assay for CTU2 is not available on ENCORE database.





88 RBPs can affect the gene expression of CTU2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
CTU2ENSG00000174177.8609.26340318.926300.933703.156502.59320HepG2AKAP1
CTU2ENSG00000174177.8305.81140176.705700.791204.971604.20020HepG2BOP1
CTU2ENSG00000174177.8103.48890162.22320-0.648502.314701.67800HepG2CPSF6
CTU2ENSG00000174177.8290.04510149.033000.960508.037707.04910HepG2CELF1
CTU2ENSG00000174177.8200.9884083.883301.2606010.208209.05320HepG2DNAJC2
CTU2ENSG00000174177.8153.6220095.565500.684702.663901.52010HepG2FAM120A
CTU2ENSG00000174177.8139.60030247.17590-0.824204.791003.77190HepG2FUBP3
CTU2ENSG00000174177.8110.55330183.88650-0.734102.747802.10820HepG2GPKOW
CTU2ENSG00000174177.8305.09920138.850701.135607.561805.21720HepG2HNRNPA0
CTU2ENSG00000174177.8213.21560135.577600.653102.709201.32310HepG2HNRNPAB
CTU2ENSG00000174177.8433.15770264.537300.711303.002302.27610HepG2HNRNPK
CTU2ENSG00000174177.8233.69880145.976400.678804.018303.21830HepG2HNRNPL
CTU2ENSG00000174177.887.41470175.48680-1.005404.482003.69920HepG2HNRNPLL
CTU2ENSG00000174177.8200.6789094.419901.087607.519806.55850HepG2HNRNPU
CTU2ENSG00000174177.8246.39210156.448900.655202.921601.69260HepG2KHDRBS1
CTU2ENSG00000174177.8194.17950115.153000.753702.929001.76210HepG2LARP7
CTU2ENSG00000174177.8526.77340283.040200.896103.741103.01730HepG2MATR3
CTU2ENSG00000174177.8275.46970158.903400.793605.465904.40030HepG2NOL12
CTU2ENSG00000174177.885.45030155.60710-0.864802.946002.17470HepG2NSUN2
CTU2ENSG00000174177.8296.74890149.994000.984204.879303.67270HepG2PABPC1
CTU2ENSG00000174177.8170.0741084.215701.013905.811204.77430HepG2PPIL4
CTU2ENSG00000174177.8455.98840161.020901.5016026.4291024.97550HepG2PUM1
CTU2ENSG00000174177.8395.81760301.111700.394402.153901.38480HepG2RBM15
CTU2ENSG00000174177.8235.48160138.867400.761803.006101.97060HepG2RBM27
CTU2ENSG00000174177.8174.92960104.016300.749903.074102.43090HepG2RPS19
CTU2ENSG00000174177.8228.68440128.052300.836503.130402.27870HepG2RPS2
CTU2ENSG00000174177.8222.53090130.735400.767303.053101.92290HepG2RPS5
CTU2ENSG00000174177.8176.8331084.087601.072306.569605.64020HepG2SAFB2
CTU2ENSG00000174177.8282.16170155.241100.861904.839103.10840HepG2SART3
CTU2ENSG00000174177.8399.23680250.820300.670503.899503.09320HepG2SF3A3
CTU2ENSG00000174177.8239.57550145.441700.719904.538503.67430HepG2SLBP
CTU2ENSG00000174177.8172.0119098.064600.810604.117603.35950HepG2SMN1
CTU2ENSG00000174177.8236.9007085.721301.466508.231606.53600HepG2SMNDC1
CTU2ENSG00000174177.8106.55290193.26600-0.859003.120802.29030HepG2SNRNP70
CTU2ENSG00000174177.8331.87830482.81750-0.540802.388301.91140HepG2SRFBP1
CTU2ENSG00000174177.8167.26120302.33770-0.854106.378905.73330HepG2SRSF1
CTU2ENSG00000174177.8310.72070149.767101.052804.801504.01420HepG2SRSF5
CTU2ENSG00000174177.8151.04750245.95710-0.703404.601403.92230HepG2SRSF9
CTU2ENSG00000174177.8214.34980419.14990-0.967505.255704.59250HepG2SSB
CTU2ENSG00000174177.8286.79850143.447800.999406.491704.74340HepG2STIP1
CTU2ENSG00000174177.8400.62750170.327401.233907.514706.57110HepG2SUCLG1
CTU2ENSG00000174177.892.67060160.30820-0.790701.974101.38850HepG2SUPV3L1
CTU2ENSG00000174177.8134.85890271.71830-1.010707.735606.87460HepG2TAF15
CTU2ENSG00000174177.8235.8864092.565701.3494012.1493011.08890HepG2TRIM56
CTU2ENSG00000174177.8257.6426094.673001.444202.807602.04180HepG2UCHL5
CTU2ENSG00000174177.8403.85050214.756400.911009.649308.64050HepG2UTP3
CTU2ENSG00000174177.8269.30350147.671400.866704.721003.27440HepG2XPO5
CTU2ENSG00000174177.8112.32210187.23840-0.737203.764403.00160HepG2ZC3H8
CTU2ENSG00000174177.81005.69100516.142000.9622020.9835019.53550K562AGGF1
CTU2ENSG00000174177.8685.30370494.871300.469604.767002.74720K562AKAP1
CTU2ENSG00000174177.8947.07430537.080600.818205.584304.63950K562AKAP8L
CTU2ENSG00000174177.81257.93240922.375000.447503.832902.33940K562APOBEC3C
CTU2ENSG00000174177.8819.489901124.67140-0.456701.993001.47990K562AQR
CTU2ENSG00000174177.8836.72430563.548600.570107.269605.69000K562ATP5C1
CTU2ENSG00000174177.8578.18410365.266900.662506.267304.79840K562BCLAF1
CTU2ENSG00000174177.8909.03560702.943300.370803.581102.31600K562CPEB4
CTU2ENSG00000174177.8483.22240277.109500.802102.860101.78670K562CSTF2
CTU2ENSG00000174177.81033.584601285.74820-0.315002.469001.54890K562CELF1
CTU2ENSG00000174177.8582.42940320.175900.863104.681502.95200K562DDX27
CTU2ENSG00000174177.81207.19500727.206100.7311014.5290013.15210K562DDX47
CTU2ENSG00000174177.8549.10300360.622300.606503.477601.56150K562DDX51
CTU2ENSG00000174177.8720.35760508.377700.502705.152703.18550K562DDX6
CTU2ENSG00000174177.8919.22250577.865100.6696010.425308.50200K562DKC1
CTU2ENSG00000174177.8519.79380333.700400.639304.394103.22620K562EFTUD2
CTU2ENSG00000174177.8557.72820376.890500.565302.469501.52340K562EIF3A
CTU2ENSG00000174177.8325.88360141.390401.2046011.6902010.03350K562EIF3G
CTU2ENSG00000174177.8599.55400471.764600.345702.558501.46210K562EIF4B
CTU2ENSG00000174177.8127.51180260.48140-1.030506.755905.39830K562FMR1
CTU2ENSG00000174177.8849.89640544.795300.641506.594905.71800K562FXR1
CTU2ENSG00000174177.816.10370112.86680-2.8092012.0675010.37870K562G3BP2
CTU2ENSG00000174177.81576.661301018.779100.629905.654904.57070K562GRSF1
CTU2ENSG00000174177.8586.50600351.315400.739305.724104.32030K562HNRNPM
CTU2ENSG00000174177.8541.30020224.857901.267302.572801.59580K562IGF2BP2
CTU2ENSG00000174177.8107.56880208.70580-0.956204.245503.06350K562KRR1
CTU2ENSG00000174177.8533.66110236.059001.1767012.1922010.33690K562MAGOH
CTU2ENSG00000174177.8480.45110235.541001.028304.222303.06160K562MATR3
CTU2ENSG00000174177.8721.95830484.871900.574204.997703.84260K562PPIG
CTU2ENSG00000174177.8578.16460324.732200.832103.723202.85270K562PRPF8
CTU2ENSG00000174177.8548.93530229.365401.2589016.1997014.66250K562PTBP1
CTU2ENSG00000174177.81013.42400532.554300.9281012.3187011.21980K562PUS1
CTU2ENSG00000174177.8907.72870518.962200.8065012.9262011.64400K562RBM15
CTU2ENSG00000174177.8567.72540330.683600.779604.608903.55270K562RPS19
CTU2ENSG00000174177.8330.41480202.419300.706802.307901.40340K562RPS3
CTU2ENSG00000174177.8215.62390117.232200.879005.389204.16800K562SF3B4
CTU2ENSG00000174177.864.65720129.83120-1.005804.019202.00650K562SND1
CTU2ENSG00000174177.8441.03800224.883500.971605.031904.08150K562SRSF1
CTU2ENSG00000174177.8286.72410195.391400.553202.587401.57640K562SRSF4
CTU2ENSG00000174177.8384.85600212.457100.857007.033405.25010K562SRSF5
CTU2ENSG00000174177.8397.53810560.31700-0.495203.178901.70460K562SSRP1
CTU2ENSG00000174177.843.41610110.78120-1.351404.520902.49210K562TAF15
CTU2ENSG00000174177.8463.81810227.534401.027406.548505.41840K562TARDBP
CTU2ENSG00000174177.8473.82580219.499001.110004.769803.65040K562TIA1
CTU2ENSG00000174177.8434.04130215.541401.009806.522004.67490K562TRA2A
CTU2ENSG00000174177.850.00900112.88850-1.174604.685903.64670K562U2AF2
CTU2ENSG00000174177.8755.82260904.51210-0.259102.185901.54190K562UPF1
CTU2ENSG00000174177.8596.98960773.95380-0.374502.763301.88610K562WDR3
CTU2ENSG00000174177.8938.744801267.15420-0.432802.841401.96500K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for CTU2 is not available on ENCORE database.





15 RBPs can affect the splicing of CTU2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SECTU2ENSG00000174177.8chr16+887763458877642488773543887736188877663088776690-0.413000.002640.04559excludedHepG2U2AF1
SECTU2ENSG00000174177.8chr16+887763458877642488773553887736188877663088776690-0.081000.000030.00066excludedK562AQR
RICTU2ENSG00000174177.8chr16+8878079088781145887807908878089488780994887811450.082000.000920.02443includedHepG2FTO
RICTU2ENSG00000174177.8chr16+887807908878114588780790887808948878099488781145-0.094000.005530.05480excludedHepG2NCBP2
RICTU2ENSG00000174177.8chr16+8878079088781145887807908878089488780994887811450.162000.000000.00000includedK562AQR
MXECTU2ENSG00000174177.8chr16+8877354388773618887766308877669088772890887730068877804288778103-0.135000.004890.099472includedK562RBM15
MXECTU2ENSG00000174177.8chr16+8877354388773618887786818877879188772890887730068877902988779313-0.165000.000030.001342includedK562PUS1
MXECTU2ENSG00000174177.8chr16+88773543887736188877634588776424887728908877300688776630887766900.379000.000000.000001includedK562NONO
MXECTU2ENSG00000174177.8chr16+88773543887736188877634588776424887728908877300688776630887766900.371000.000390.024671includedHepG2XPO5
MXECTU2ENSG00000174177.8chr16+88773543887736188877634588776424887728908877300688776630887766900.360000.000000.000071includedK562EFTUD2
MXECTU2ENSG00000174177.8chr16+88773543887736188877634588776424887728908877300688776630887766900.382000.000060.007611includedHepG2NOL12
MXECTU2ENSG00000174177.8chr16+8877354388773618887763458877642488772890887730068877663088776690-0.131000.001120.080162includedK562PUM1
MXECTU2ENSG00000174177.8chr16+88773543887736188877634588776424887728908877300688776630887766900.220000.000320.020161includedK562IGF2BP2
MXECTU2ENSG00000174177.8chr16+88773543887736188877634588776424887728908877300688776630887766900.364000.000000.000001includedK562PRPF8
MXECTU2ENSG00000174177.8chr16+88773543887736188877634588776424887728908877300688776630887766900.530000.000000.000001includedK562SUPV3L1
MXECTU2ENSG00000174177.8chr16+88773543887736188877634588776424887728908877300688776630887766900.293000.000360.068391includedK562GEMIN5

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for CTU2 is not avaliable on ENCORE database.