CRTC2

General Information

Gene Name       : CRTC2
Gene ID             : ENSG00000160741.16
Essential Gene : No

Functions

Localization

Domains (AlphaFold: CRTC2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878CRTC2ENSG00000160741.1613.6233.6123.61ENCSR000AEF
HepG2CRTC2ENSG00000160741.1613.918.5811.25ENCSR985KAT
K562CRTC2ENSG00000160741.1617.3616.1616.76ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for CRTC2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • CRTC2 RNA is bound by 24 proteins.  







eCLIP assay for CRTC2 is not avaliable on ENCORE database.





24 proteins are bound to CRTC2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr1153921788153921831-3'-UTR,CDS,intron-Distal4.071293.06406HepG2IGF2BP1
chr1153921785153921861-3'-UTR,CDS,intron-Distal,intron-Proximal3.954103.34601K562HNRNPK
chr1153923823153923935-3'-UTR,CDS,intron-Distal3.3468211.83508K562PCBP1
chr1153924573153924683-3'-UTR,CDS,intron-Distal,intron-Proximal4.500065.82109K562IGF2BP2
chr1153924066153924117-3'-UTR,CDS,intron-Distal,intron-Proximal4.540733.97933HepG2DDX59
chr1153925232153925331-3'-UTR,CDS,intron-Distal,intron-Proximal6.1882713.28065K562AQR
chr1153920982153921045-3'-UTR,CDS,intron-Distal5.3793511.73557K562LIN28B
chr1153925067153925138-3'-UTR,CDS,intron-Distal,intron-Proximal4.432627.50107K562AQR
chr1153924000153924098-3'-UTR,CDS,intron-Distal,intron-Proximal3.690355.89225K562PCBP1
chr1153921289153921335-3'-UTR,intron-Distal,intron-Proximal3.963333.71567HepG2RBFOX2
chr1153923996153924042-3'-UTR,CDS,intron-Distal5.609289.83211HepG2PCBP2
chr1153921718153921788-3'-UTR,CDS,intron-Distal4.540594.59164HepG2IGF2BP1
chr1153921747153921862-3'-UTR,CDS,intron-Distal,intron-Proximal3.723699.20480K562IGF2BP2
chr1153924048153924120-3'-UTR,CDS,intron-Distal,intron-Proximal3.804326.45177K562HNRNPK
chr1153925047153925107-3'-UTR,CDS,intron-Distal,intron-Proximal3.059403.25772K562ZNF622
chr1153923838153923929-3'-UTR,CDS,intron-Distal3.944375.89669K562HNRNPK
chr1153923829153923931-3'-UTR,CDS,intron-Distal3.902709.50194HepG2PCBP2
chr1153924882153924978-3'-UTR,CDS,intron-Distal,intron-Proximal5.4694317.59328K562SF3B4
chr1153924061153924111-3'-UTR,CDS,intron-Distal,intron-Proximal4.699357.31085HepG2PCBP2
chr1153924066153924129-3'-UTR,CDS,intron-Distal,intron-Proximal3.927873.76295K562IGF2BP2
chr1153924055153924122-3'-UTR,CDS,intron-Distal,intron-Proximal3.130163.38830K562ILF3
chr1153923810153923900-3'-UTR,CDS,intron-Distal3.650165.85178HepG2IGF2BP1
chr1153923829153923902-3'-UTR,CDS,intron-Distal4.285334.83379HepG2HNRNPK
chr1153930928153931009-5'-UTR,CDS,intron-Distal3.829385.62144HepG2NCBP2
chr1153930924153931014-5'-UTR,CDS,intron-Distal5.170209.89700HepG2PRPF4
chr1153925708153925788-5'-UTR,CDS,intron-Distal,intron-Proximal3.227758.00684HepG2PRPF8
chr1153930932153931014-5'-UTR,CDS,intron-Distal3.468483.44826K562METAP2
chr1153930876153930986-5'-UTR,CDS,intron-Distal3.269306.27819HepG2PPIG
chr1153930940153931011-5'-UTR,CDS,intron-Distal4.331743.17390K562NCBP2
chr1153930929153931021-5'-UTR,CDS,intron-Distal4.527575.27767HepG2GTF2F1
chr1153931009153931082-5'-UTR,intron-Distal,intron-Proximal4.279623.98935HepG2NCBP2
chr1153930920153931004-5'-UTR,CDS,intron-Distal3.986394.95463K562GTF2F1
chr1153930922153931001-5'-UTR,CDS,intron-Distal3.950837.66029K562CSTF2T
chr1153925112153925155-CDS,intron-Distal,intron-Proximal5.501507.81477K562SF3B4
chr1153927413153927503-CDS,intron-Distal,intron-Proximal3.645907.03098HepG2EFTUD2
chr1153926690153926741-CDS,intron-Distal,intron-Proximal3.650914.83899HepG2PRPF8
chr1153926029153926075-CDS,intron-Distal3.284413.13705K562BUD13
chr1153927426153927511-CDS,intron-Distal,intron-Proximal4.280529.41299K562EFTUD2
chr1153926067153926124-CDS,intron-Distal,intron-Proximal4.050935.16342K562SF3B4
chr1153927462153927567-CDS,intron-Distal,intron-Proximal4.1308423.52891HepG2PRPF8
chr1153927487153927555-CDS,intron-Distal,intron-Proximal4.127148.10864K562PRPF8
chr1153926052153926133-CDS,intron-Distal,intron-Proximal3.060563.13970HepG2SF3B4
chr1153927445153927508-CDS,intron-Distal,intron-Proximal3.758459.47061K562SF3B4
chr1153930140153930254-intron-Distal5.5651412.04483HepG2HNRNPM
chr1153930506153930569-intron-Distal4.370194.70168K562CSTF2T
chr1153923144153923193-intron-Distal5.720828.51022HepG2XPO5
chr1153925176153925231-intron-Distal,intron-Proximal4.215594.84268K562SF3B4
chr1153930513153930608-intron-Distal,intron-Proximal4.305575.16036HepG2CSTF2T
chr1153926683153926701-intron-Distal,intron-Proximal3.649864.41130K562AQR
chr1153922762153922806-intron-Distal5.343326.40067K562PTBP1
chr1153922772153922806-intron-Distal4.473613.74583HepG2PTBP1
chr1153922939153923046-intron-Distal4.152055.65979HepG2PTBP1
chr1153924385153924450-intron-Distal,intron-Proximal4.210815.47926K562AQR
chr1153925172153925231-intron-Distal,intron-Proximal3.518944.29246HepG2SF3B4
chr1153923691153923733-intron-Distal,intron-Proximal4.734824.86944K562AQR
chr1153922899153922964-intron-Distal5.393086.90462K562PTBP1
chr1153923193153923241-intron-Distal3.769545.48327HepG2XPO5
chr1153926701153926731-intron-Distal,intron-Proximal3.654144.88100K562AQR
chr1153924450153924493-intron-Distal,intron-Proximal5.786599.41643K562AQR
chr1153923249153923291-intron-Distal4.185563.18981K562PTBP1
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for CRTC2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for CRTC2 is not available on ENCORE database.

  • 86 RBPs can affect the levels of CRTC2.  








The Knockdown/knockout RNA-Seq assay for CRTC2 is not available on ENCORE database.





86 RBPs can affect the gene expression of CRTC2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
CRTC2ENSG00000160741.12701.58890543.640300.367903.236202.41350HepG2AKAP8L
CRTC2ENSG00000160741.12557.79440427.422100.384001.976001.30900HepG2ASCC1
CRTC2ENSG00000160741.121086.30320830.810600.386702.897301.63740HepG2BUD13
CRTC2ENSG00000160741.12583.98390767.85770-0.394902.193901.50180HepG2CALR
CRTC2ENSG00000160741.12611.05260406.088800.589404.158603.22180HepG2CIRBP
CRTC2ENSG00000160741.12299.92420405.38950-0.434702.644601.65100HepG2YBX3
CRTC2ENSG00000160741.12216.68980346.91980-0.679003.387001.82810HepG2CSTF2T
CRTC2ENSG00000160741.12690.79940532.538800.375303.029002.36180HepG2CELF1
CRTC2ENSG00000160741.12263.01390373.47800-0.505902.815102.13260HepG2DDX21
CRTC2ENSG00000160741.12746.62850494.813800.593404.381803.60900HepG2DDX3X
CRTC2ENSG00000160741.12628.79290936.86150-0.575304.365403.10650HepG2DDX5
CRTC2ENSG00000160741.12744.99000425.186200.809006.824605.88960HepG2DDX6
CRTC2ENSG00000160741.12618.93900398.053200.636702.286701.64240HepG2DNAJC21
CRTC2ENSG00000160741.12480.73160394.551200.284901.910601.35030HepG2DNAJC2
CRTC2ENSG00000160741.12307.49290423.90770-0.463202.564901.49460HepG2EFTUD2
CRTC2ENSG00000160741.12609.89510408.611900.577703.863803.17000HepG2EIF2S1
CRTC2ENSG00000160741.12639.918201027.01410-0.682505.975903.21770HepG2EIF3H
CRTC2ENSG00000160741.12625.96090451.501300.471202.621501.99830HepG2EIF4A3
CRTC2ENSG00000160741.12829.954901120.03230-0.432402.912602.12270HepG2FIP1L1
CRTC2ENSG00000160741.121643.315901021.742500.685502.749701.73810HepG2FTO
CRTC2ENSG00000160741.12669.82140455.736100.555503.911903.09900HepG2FXR1
CRTC2ENSG00000160741.12583.54250422.662000.465202.653602.00120HepG2G3BP1
CRTC2ENSG00000160741.12619.26080772.56510-0.319102.392101.50650HepG2HNRNPM
CRTC2ENSG00000160741.12645.53640429.591100.587404.242603.42270HepG2IGF2BP2
CRTC2ENSG00000160741.12607.31310453.582800.421004.398703.49340HepG2ILF2
CRTC2ENSG00000160741.12573.02740906.14880-0.661107.897406.59520HepG2MSI2
CRTC2ENSG00000160741.12722.10260469.189800.621904.548703.74680HepG2NCBP2
CRTC2ENSG00000160741.12708.53790567.711600.319602.511001.78680HepG2NOL12
CRTC2ENSG00000160741.121311.47320978.420000.422603.447802.61250HepG2NSUN2
CRTC2ENSG00000160741.12275.37140439.52920-0.674606.339105.13800HepG2PARN
CRTC2ENSG00000160741.12508.66250396.057400.360902.382101.69320HepG2PPIL4
CRTC2ENSG00000160741.12509.19270628.65820-0.304102.273401.56470HepG2PRPF4
CRTC2ENSG00000160741.12738.35050574.901600.360902.746902.07900HepG2PUM2
CRTC2ENSG00000160741.121312.551401070.725900.293702.552101.72540HepG2RBM15
CRTC2ENSG00000160741.12956.35080406.811201.233104.115601.83410HepG2RBM17
CRTC2ENSG00000160741.12851.95700595.333800.517002.042401.57900HepG2RBM22
CRTC2ENSG00000160741.12577.31350401.732000.523003.192602.53860HepG2RPS19
CRTC2ENSG00000160741.12535.29810395.444700.436803.830003.09290HepG2SAFB2
CRTC2ENSG00000160741.121001.79620393.096901.349505.000703.07120HepG2SF1
CRTC2ENSG00000160741.121464.28620891.643900.715605.624604.64220HepG2SF3A3
CRTC2ENSG00000160741.12503.27680368.576300.449302.151401.31760HepG2SMNDC1
CRTC2ENSG00000160741.12971.13000351.250001.467106.391504.19250HepG2SNRNP200
CRTC2ENSG00000160741.121301.82820672.370100.9531011.7677010.92560HepG2SRFBP1
CRTC2ENSG00000160741.121678.006101175.204400.513703.661602.49470HepG2SRSF3
CRTC2ENSG00000160741.12369.52910474.40440-0.360402.120401.61750HepG2TAF15
CRTC2ENSG00000160741.121327.532201075.465400.303702.079701.43880HepG2TARDBP
CRTC2ENSG00000160741.12680.97410431.462500.658303.424102.87960HepG2TIAL1
CRTC2ENSG00000160741.12645.63230435.336800.568504.020003.36560HepG2TRIM56
CRTC2ENSG00000160741.121594.23740957.925700.734808.583507.47170HepG2U2AF1
CRTC2ENSG00000160741.121700.61580408.668302.0570010.870608.80990HepG2U2AF2
CRTC2ENSG00000160741.121064.29580869.675400.291302.189401.68660HepG2ZNF622
CRTC2ENSG00000160741.121956.258601021.509200.9373029.4227027.67270K562AGGF1
CRTC2ENSG00000160741.121592.170301122.475500.504205.572704.05710K562AKAP8
CRTC2ENSG00000160741.122115.966401062.924500.9932013.5842011.97070K562AKAP8L
CRTC2ENSG00000160741.121663.64790824.714101.0123017.1970015.89850K562AQR
CRTC2ENSG00000160741.121555.617701115.259600.480005.172103.87930K562ATP5C1
CRTC2ENSG00000160741.121273.07200806.599700.658302.642401.62040K562CCAR1
CRTC2ENSG00000160741.122310.859001452.272500.670004.135503.36030K562DDX47
CRTC2ENSG00000160741.121645.759201143.796400.524808.064106.43360K562DKC1
CRTC2ENSG00000160741.12747.42590452.985000.722405.942304.56790K562EFTUD2
CRTC2ENSG00000160741.121638.92780820.402700.998208.534206.73450K562EIF3A
CRTC2ENSG00000160741.12349.90390248.193600.495403.184702.33280K562EIF3G
CRTC2ENSG00000160741.12669.92760508.341500.398102.760001.94010K562EIF4A3
CRTC2ENSG00000160741.12580.52390457.791400.342602.445801.38140K562EIF4B
CRTC2ENSG00000160741.1278.64680253.01080-1.685705.682504.58780K562G3BP2
CRTC2ENSG00000160741.121672.11670823.156001.022303.411502.01060K562HNRNPA2B1
CRTC2ENSG00000160741.12922.56560687.947100.423303.530702.86680K562HNRNPC
CRTC2ENSG00000160741.12872.25220614.338700.505604.587303.07020K562HNRNPF
CRTC2ENSG00000160741.12646.81400394.492200.713305.299903.69120K562IGF2BP2
CRTC2ENSG00000160741.121734.125001128.036100.620308.864007.16700K562KIF1C
CRTC2ENSG00000160741.121107.69720697.737200.666706.707904.24230K562LIN28B
CRTC2ENSG00000160741.12900.70000613.434300.554005.584203.31080K562LSM11
CRTC2ENSG00000160741.121682.642001079.802000.639903.211502.02850K562MAK16
CRTC2ENSG00000160741.122098.696501263.684300.731809.499007.61360K562MBNL1
CRTC2ENSG00000160741.121633.02540885.750500.882509.172107.19480K562NAA15
CRTC2ENSG00000160741.121491.595601236.978100.269903.759502.90520K562NSUN2
CRTC2ENSG00000160741.121031.21560677.351300.606305.214703.03640K562NUSAP1
CRTC2ENSG00000160741.121704.38020719.479701.244103.344302.22550K562PABPN1
CRTC2ENSG00000160741.12550.70390405.136600.442803.242201.77850K562PCBP1
CRTC2ENSG00000160741.12511.58870368.612800.472803.080502.04870K562PCBP2
CRTC2ENSG00000160741.121003.83120671.650800.579603.971102.21790K562PHF6
CRTC2ENSG00000160741.12720.16080440.812100.708103.996203.09470K562PRPF8
CRTC2ENSG00000160741.121101.01040616.816900.8358011.588809.46130K562PSIP1
CRTC2ENSG00000160741.122878.041001054.144901.448907.274006.44030K562PUS1
CRTC2ENSG00000160741.122237.705301027.092601.1234013.9605012.62200K562RBM15
CRTC2ENSG00000160741.12644.43930385.882300.739807.495406.02340K562RBM22
CRTC2ENSG00000160741.12892.69750562.767000.665507.975006.29550K562RCC2
CRTC2ENSG00000160741.12766.22170448.860300.771406.123604.90150K562RPS19
CRTC2ENSG00000160741.121841.50420657.666401.485409.268006.68390K562SF1
CRTC2ENSG00000160741.121646.623101220.568500.431906.103404.93050K562SF3A3
CRTC2ENSG00000160741.12432.02400262.747400.717305.586704.34480K562SF3B4
CRTC2ENSG00000160741.121750.86260801.307301.127502.843801.51670K562SFPQ
CRTC2ENSG00000160741.122082.45980755.781301.462107.308604.97270K562SNRNP200
CRTC2ENSG00000160741.12996.08290533.487900.900708.564706.48330K562SRFBP1
CRTC2ENSG00000160741.121447.614301250.497600.211102.154701.31980K562SRPK2
CRTC2ENSG00000160741.12666.53950394.687400.755908.330307.11110K562SRSF1
CRTC2ENSG00000160741.12693.18540399.387500.795406.502805.37610K562TARDBP
CRTC2ENSG00000160741.12542.01320385.270600.492403.728902.75880K562TIA1
CRTC2ENSG00000160741.121012.94170593.274600.771706.359904.88250K562TIAL1
CRTC2ENSG00000160741.12539.70890378.211800.512903.577802.30430K562TRA2A
CRTC2ENSG00000160741.121202.38700630.279100.9317014.1569011.63010K562TRIM56
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for CRTC2 is not available on ENCORE database.





15 RBPs can affect the splicing of CRTC2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SECRTC2ENSG00000160741.12chr1-153926013153926082153925741153925845153926730153926792-0.262000.000040.00142excludedHepG2U2AF1
SECRTC2ENSG00000160741.12chr1-153925741153925845153925280153925310153926013153926082-0.133000.003810.04260excludedHepG2U2AF2
A3SSCRTC2ENSG00000160741.12chr1-1539252801539253551539252801539253101539257411539258450.089000.000180.00151longerK562AQR
A3SSCRTC2ENSG00000160741.12chr1-1539275401539276801539275401539276421539308201539311010.159000.001060.00730longerK562AQR
A3SSCRTC2ENSG00000160741.12chr1-1539260131539261651539260131539260821539267301539267920.222000.000000.00003longerK562AQR
A3SSCRTC2ENSG00000160741.12chr1-1539257911539259311539257911539258451539260131539261650.170000.000000.00000longerK562AQR
A3SSCRTC2ENSG00000160741.12chr1-1539209331539211401539209331539211201539215901539218600.379000.000000.00000longerK562AQR
RICRTC2ENSG00000160741.12chr1-1539237351539245721539237351539241421539243311539245720.404000.000190.01777includedK562PPIL4
RICRTC2ENSG00000160741.12chr1-1539237351539245721539237351539241421539243311539245720.204000.000120.00107includedK562PUS1
RICRTC2ENSG00000160741.12chr1-1539273481539276421539273481539274651539275401539276420.162000.000970.00723includedK562PUS1
RICRTC2ENSG00000160741.12chr1-153923735153924572153923735153924142153924331153924572-0.578000.000880.02338excludedK562HNRNPC
RICRTC2ENSG00000160741.12chr1-1539273481539276421539273481539274651539275401539276420.136000.006230.06231includedK562AGGF1
RICRTC2ENSG00000160741.12chr1-1539237351539245721539237351539241421539243311539245720.145000.012950.09499includedK562AKAP8L
RICRTC2ENSG00000160741.12chr1-1539273481539276421539273481539274651539275401539276420.142000.003740.03467includedK562AKAP8L
RICRTC2ENSG00000160741.12chr1-1539273481539276421539273481539274651539275401539276420.420000.003880.03560includedHepG2TAF15
RICRTC2ENSG00000160741.12chr1-1539237351539245721539237351539241421539243311539245720.291000.002940.09767includedK562SBDS
RICRTC2ENSG00000160741.12chr1-1539273481539276421539273481539274651539275401539276420.181000.000780.00537includedK562AQR
MXECRTC2ENSG00000160741.12chr1-153923735153924142153924493153924738153921590153921860153924872153924922-0.148000.000440.035772includedK562LARP4
MXECRTC2ENSG00000160741.12chr1-1539237351539241421539244931539247381539215901539218601539248721539249220.135000.000020.000821includedHepG2FTO
MXECRTC2ENSG00000160741.12chr1-153923735153924142153924493153924738153921590153921860153924872153924922-0.159000.000140.004432includedK562DROSHA
MXECRTC2ENSG00000160741.12chr1-153923735153924142153924493153924738153921590153921860153924872153924922-0.175000.001160.016992includedHepG2SFPQ
MXECRTC2ENSG00000160741.12chr1-1539260131539261561539267301539267921539257911539258451539273481539274650.139000.003340.021871includedHepG2U2AF2
MXECRTC2ENSG00000160741.12chr1-153923735153924142153924493153924738153921590153921860153924872153924922-0.286000.000000.000012includedHepG2U2AF2
MXECRTC2ENSG00000160741.12chr1-153923735153923841153924493153924738153921590153921860153924872153924922-0.283000.000000.000012includedHepG2U2AF2
MXECRTC2ENSG00000160741.12chr1-153923735153924142153924493153924738153921590153921860153924872153924922-0.270000.000000.000102includedHepG2HNRNPUL1
MXECRTC2ENSG00000160741.12chr1-153921590153921860153923735153924142153920933153921120153924493153924738-0.148000.000060.004582includedK562AKAP8L
MXECRTC2ENSG00000160741.12chr1-153923735153924142153924493153924738153921590153921860153924872153924922-0.161000.000120.005332includedK562HNRNPUL1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for CRTC2 is not avaliable on ENCORE database.