WDR46

General Information

Gene Name       : WDR46
Gene ID             : ENSG00000227057.9
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: WDR46)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878WDR46ENSG00000227057.937.2045.5141.36ENCSR000AEF
HepG2WDR46ENSG00000227057.978.2757.1967.73ENCSR985KAT
K562WDR46ENSG00000227057.960.2562.6261.44ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for WDR46 is not avaliable on ENCORE database.



Proteins bound to RNA
  • WDR46 RNA is bound by 21 proteins.  







eCLIP assay for WDR46 is not avaliable on ENCORE database.





21 proteins are bound to WDR46 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr63324702133247131-3'-UTR,CDS,intron-Distal3.384493.08948K562DDX55
chr63324697133247061-3'-UTR,CDS,intron-Distal4.559245.77937HepG2LARP4
chr63324693333247074-3'-UTR,CDS,intron-Distal5.2411616.83921K562PABPC4
chr63324703133247185-3'-UTR,CDS,intron-Distal,intron-Proximal4.902355.32242HepG2PABPN1
chr63324695333247012-3'-UTR,intron-Distal4.999638.90110K562YBX3
chr63325692733256985-5'-UTR,CDS,intron-Distal,intron-Proximal3.281663.59926K562DDX3X
chr63325573733255798-CDS,intron-Distal,intron-Proximal4.100306.19659HepG2AQR
chr63324829533248428-CDS,intron-Distal,intron-Proximal5.952649.67979K562EFTUD2
chr63325522833255280-CDS,intron-Distal,intron-Proximal5.176485.73530K562DDX24
chr63324754033247624-CDS,intron-Distal,intron-Proximal3.340515.80035HepG2PPIG
chr63324841133248502-CDS,intron-Distal,intron-Proximal3.014125.27209HepG2RBFOX2
chr63324712133247150-CDS,intron-Distal4.574494.42734K562UCHL5
chr63325574233255781-CDS,intron-Distal,intron-Proximal4.034624.21087HepG2GRWD1
chr63324828333248356-CDS,intron-Distal,intron-Proximal4.320456.10653K562SF3B4
chr63325575933255800-CDS,intron-Distal,intron-Proximal3.164683.39477K562BUD13
chr63325539533255423-CDS,intron-Distal,intron-Proximal3.727945.24452HepG2PPIG
chr63325595733256015-CDS,intron-Distal,intron-Proximal5.370766.53290K562DDX24
chr63324736433247387-CDS,intron-Distal4.124263.59941K562UCHL5
chr63325595633256052-CDS,intron-Distal,intron-Proximal3.922568.66987HepG2AQR
chr63325659333256668-CDS,intron-Distal,intron-Proximal3.033763.09129HepG2GRWD1
chr63325587333255956-CDS,intron-Distal,intron-Proximal5.159958.23509HepG2AQR
chr63324825533248312-CDS,intron-Distal,intron-Proximal3.904883.23561HepG2U2AF1
chr63324762933247693-CDS,intron-Distal,intron-Proximal4.437687.39218K562SF3B4
chr63324841433248463-CDS,intron-Distal,intron-Proximal3.993538.47952HepG2PRPF8
chr63325592933256012-CDS,intron-Distal3.542517.50303K562UCHL5
chr63324811033248215-CDS,intron-Distal,intron-Proximal6.1915611.90432HepG2EFTUD2
chr63325593033255978-CDS,intron-Distal3.433476.06370HepG2BUD13
chr63325545433255492-CDS,intron-Distal3.083533.80299HepG2GRWD1
chr63325596833256031-CDS,intron-Distal,intron-Proximal3.989059.61107HepG2PRPF8
chr63324736433247379-CDS,intron-Distal3.562483.32039HepG2PPIG
chr63324828233248329-CDS,intron-Distal,intron-Proximal4.672064.86944K562AQR
chr63324820833248268-CDS,intron-Distal4.5159311.01413HepG2PPIG
chr63325545833255484-CDS,intron-Distal3.333623.07653K562ZNF622
chr63324711433247151-CDS,intron-Distal3.514454.72530HepG2G3BP1
chr63324712533247149-CDS,intron-Distal4.202103.77023K562ZNF622
chr63325594733256008-CDS,intron-Distal3.177646.05769K562ZNF622
chr63325576933255814-CDS,intron-Distal,intron-Proximal4.964545.17615K562AQR
chr63324816233248207-CDS,intron-Distal,intron-Proximal5.119067.26081HepG2PRPF8
chr63325526033255283-CDS,intron-Distal,intron-Proximal3.404004.30677K562YBX3
chr63325596633256024-CDS,intron-Distal,intron-Proximal3.967667.30031K562AQR
chr63325672833256797-CDS,intron-Distal,intron-Proximal3.329044.41873K562ZNF800
chr63325593533255958-CDS,intron-Distal3.723455.40651HepG2PPIG
chr63324821533248300-CDS,intron-Distal,intron-Proximal3.791175.51703K562BUD13
chr63325658633256642-CDS,intron-Distal4.007036.11943K562UCHL5
chr63324739433247458-intron-Distal,intron-Proximal5.104395.58150K562SF3B4
chr63324811733248186-intron-Distal,intron-Proximal4.939614.24111K562EFTUD2
chr63324812533248169-intron-Distal,intron-Proximal4.770934.75882HepG2RBM22
chr63325602433256068-intron-Distal,intron-Proximal4.708594.13847K562AQR
chr63324715333247188-intron-Distal,intron-Proximal4.367473.95187HepG2AQR
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for WDR46 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for WDR46 is not available on ENCORE database.

  • 82 RBPs can affect the levels of WDR46.  








The Knockdown/knockout RNA-Seq assay for WDR46 is not available on ENCORE database.





82 RBPs can affect the gene expression of WDR46 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
WDR46ENSG00000227057.3586.609201037.65650-0.822908.592807.12130HepG2BCLAF1
WDR46ENSG00000227057.31047.86440682.310300.618906.442705.57370HepG2BOP1
WDR46ENSG00000227057.3744.862501058.58270-0.507103.200602.14670HepG2CCAR1
WDR46ENSG00000227057.3323.54150626.37480-0.9531010.025108.79620HepG2CPSF6
WDR46ENSG00000227057.31744.569001414.265200.302704.012503.26460HepG2CELF1
WDR46ENSG00000227057.31201.624501576.23880-0.391502.823202.19140HepG2DDX3X
WDR46ENSG00000227057.3485.58740711.30230-0.550702.324801.43130HepG2DDX59
WDR46ENSG00000227057.3661.516001354.18650-1.0336013.1052011.87970HepG2DDX6
WDR46ENSG00000227057.3792.45140974.48750-0.298302.723302.05070HepG2DKC1
WDR46ENSG00000227057.3708.511101301.64880-0.8775010.907909.77850HepG2EIF2S1
WDR46ENSG00000227057.3994.849001438.39590-0.531904.183703.40210HepG2EIF4A3
WDR46ENSG00000227057.31056.743901437.05720-0.443503.457802.55490HepG2EIF4G2
WDR46ENSG00000227057.31071.489901346.37220-0.329501.994501.42610HepG2G3BP1
WDR46ENSG00000227057.3386.54200554.51240-0.520603.585302.55260HepG2GEMIN5
WDR46ENSG00000227057.3506.61070778.44560-0.619705.592104.63390HepG2HNRNPC
WDR46ENSG00000227057.3886.687001299.73420-0.551708.993107.79480HepG2HNRNPF
WDR46ENSG00000227057.31737.681801363.617800.349602.756802.06130HepG2HNRNPK
WDR46ENSG00000227057.3456.33000677.55390-0.570304.246403.48120HepG2HNRNPLL
WDR46ENSG00000227057.3898.489001279.87250-0.510403.819302.97900HepG2IGF2BP1
WDR46ENSG00000227057.31063.487001452.02830-0.449303.568702.82340HepG2MAGOH
WDR46ENSG00000227057.32042.965901460.116200.484503.895903.15840HepG2MATR3
WDR46ENSG00000227057.3452.36850691.15570-0.611503.111002.07920HepG2MTPAP
WDR46ENSG00000227057.3489.40320637.34260-0.381002.572401.40170HepG2NAA15
WDR46ENSG00000227057.31766.541801507.621900.228602.277301.58570HepG2NOL12
WDR46ENSG00000227057.31040.070801330.78510-0.355602.345001.67630HepG2PABPC4
WDR46ENSG00000227057.3951.37560765.417300.313702.974302.09910HepG2PARN
WDR46ENSG00000227057.3628.30480893.83310-0.508502.733601.69960HepG2PCBP2
WDR46ENSG00000227057.31754.195801527.915800.199102.369301.81210HepG2PUM1
WDR46ENSG00000227057.3853.171401037.48490-0.282202.857302.23390HepG2PUS1
WDR46ENSG00000227057.31027.800001425.64000-0.472105.891605.02860HepG2QKI
WDR46ENSG00000227057.31447.468501690.50230-0.223901.886801.43770HepG2RBM22
WDR46ENSG00000227057.3917.182401293.88440-0.496405.408804.49500HepG2RBM25
WDR46ENSG00000227057.31196.530701465.01300-0.292103.045902.48320HepG2NELFE
WDR46ENSG00000227057.3984.678601400.05200-0.507805.063504.17690HepG2RPLP0
WDR46ENSG00000227057.3684.67350895.91960-0.388002.252201.53560HepG2RRP9
WDR46ENSG00000227057.31251.48830920.073200.443702.819802.13940HepG2SF3A3
WDR46ENSG00000227057.3466.78040670.60780-0.522703.903203.07720HepG2SF3B1
WDR46ENSG00000227057.31076.035501370.49840-0.349004.121503.42300HepG2SF3B4
WDR46ENSG00000227057.31121.680201380.20900-0.299202.384801.72690HepG2SLBP
WDR46ENSG00000227057.31079.95380803.068800.427306.307605.39940HepG2SMN1
WDR46ENSG00000227057.31270.36170880.794200.528303.376902.30700HepG2SMNDC1
WDR46ENSG00000227057.31424.394501909.33510-0.422707.969007.24090HepG2SRFBP1
WDR46ENSG00000227057.3783.611501276.92740-0.7045013.9266012.57360HepG2SRSF7
WDR46ENSG00000227057.3897.257801163.82820-0.375304.713804.02950HepG2SRSF9
WDR46ENSG00000227057.3984.792901657.71100-0.7513019.5656018.46740HepG2SSB
WDR46ENSG00000227057.3533.85290805.89410-0.594103.132301.84580HepG2SUB1
WDR46ENSG00000227057.31990.804901616.147800.300703.528902.84260HepG2SUCLG1
WDR46ENSG00000227057.3695.267001168.86110-0.749507.373606.35440HepG2SUPV3L1
WDR46ENSG00000227057.31049.342701285.87430-0.293302.699702.14530HepG2TAF15
WDR46ENSG00000227057.31141.12360758.123600.5899010.345709.35990HepG2TRIM56
WDR46ENSG00000227057.31029.92570802.260300.360302.337601.75560HepG2U2AF1
WDR46ENSG00000227057.3876.61270690.464700.344302.019101.37000HepG2UCHL5
WDR46ENSG00000227057.3637.05060815.96820-0.357102.752202.05430HepG2UPF1
WDR46ENSG00000227057.3977.69840787.779300.311502.987502.36960HepG2UTP3
WDR46ENSG00000227057.3531.75650784.05950-0.560207.731806.70130HepG2ZC3H8
WDR46ENSG00000227057.32979.393602296.913000.375203.849302.35420K562APOBEC3C
WDR46ENSG00000227057.31336.493901614.45420-0.272603.358302.29700K562BCLAF1
WDR46ENSG00000227057.3506.50060727.01910-0.521404.059702.73400K562CCAR1
WDR46ENSG00000227057.33047.544701578.911300.9486017.7300016.20760K562DDX47
WDR46ENSG00000227057.31583.944401292.858800.292903.254802.29450K562DKC1
WDR46ENSG00000227057.31830.404202236.57670-0.289103.619902.81590K562EIF2S2
WDR46ENSG00000227057.31030.70170739.528200.478802.232001.34060K562EIF3A
WDR46ENSG00000227057.31725.71340877.246600.9760017.4955015.42970K562EIF3G
WDR46ENSG00000227057.3671.36110938.50240-0.483304.358902.30960K562FASTKD2
WDR46ENSG00000227057.3699.65190921.99190-0.398102.548101.47360K562FKBP4
WDR46ENSG00000227057.31901.710201043.841800.8653022.4295020.82380K562FXR1
WDR46ENSG00000227057.3267.98010688.86270-1.3621015.2568013.29010K562G3BP2
WDR46ENSG00000227057.31497.450201876.20830-0.325303.106001.96630K562HNRNPA1
WDR46ENSG00000227057.3617.886201062.32060-0.7818010.595809.49000K562HNRNPC
WDR46ENSG00000227057.31495.083601096.455900.447303.717502.26300K562HNRNPK
WDR46ENSG00000227057.31845.553901426.860600.371103.705402.45760K562HNRNPL
WDR46ENSG00000227057.31221.76060949.054700.364302.342701.49050K562HNRNPM
WDR46ENSG00000227057.31396.676601153.964500.275302.059601.32960K562MAGOH
WDR46ENSG00000227057.31438.120001151.519300.320502.762601.84000K562MATR3
WDR46ENSG00000227057.31389.215801573.80260-0.180002.044201.39120K562NSUN2
WDR46ENSG00000227057.3962.326801651.68730-0.779309.518707.98600K562PCBP3
WDR46ENSG00000227057.3998.931101266.92650-0.342902.936802.11050K562POLR2G
WDR46ENSG00000227057.31792.841501366.994600.391103.338702.51210K562PRPF8
WDR46ENSG00000227057.31717.038401121.200100.614809.330608.16030K562PTBP1
WDR46ENSG00000227057.33646.336702840.149100.360403.648502.71370K562PUF60
WDR46ENSG00000227057.31620.396201191.516000.443404.143903.49920K562PUS1
WDR46ENSG00000227057.31441.889701131.061100.350202.585801.53370K562NELFE
WDR46ENSG00000227057.31990.944201392.449600.515704.397903.36380K562RPS19
WDR46ENSG00000227057.3579.78980800.84690-0.466003.667602.19250K562SLBP
WDR46ENSG00000227057.31387.783101099.226800.336202.937002.21180K562SRSF1
WDR46ENSG00000227057.31267.255601533.48160-0.275102.846201.65940K562SRSF7
WDR46ENSG00000227057.31104.713801442.09930-0.384504.074602.21780K562SRSF9
WDR46ENSG00000227057.3649.46650904.90820-0.478504.991403.18840K562SSB
WDR46ENSG00000227057.3991.352701323.56710-0.417002.890801.85130K562SUPV3L1
WDR46ENSG00000227057.31703.159001270.724300.422505.031303.91690K562SYNCRIP
WDR46ENSG00000227057.31498.617001112.323400.430003.735202.90800K562TARDBP
WDR46ENSG00000227057.3607.17750916.11930-0.593404.920003.64040K562TIAL1
WDR46ENSG00000227057.31753.825202272.26280-0.373606.401204.43510K562TROVE2
WDR46ENSG00000227057.3553.99390689.58290-0.315902.156701.44730K562U2AF2
WDR46ENSG00000227057.3972.246301400.82240-0.526904.903803.50960K562UCHL5
WDR46ENSG00000227057.31432.107201668.73720-0.220602.298701.64010K562UPF1
WDR46ENSG00000227057.31048.222601427.88420-0.445904.831703.65700K562WDR3
WDR46ENSG00000227057.31754.181001484.844400.240402.875502.01250K562WDR43
WDR46ENSG00000227057.32071.703502647.24780-0.353703.364302.39980K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for WDR46 is not available on ENCORE database.





24 RBPs can affect the splicing of WDR46 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEWDR46ENSG00000227057.3chr6-3325206133252167332486923324876433254571332546710.068000.000070.00426includedHepG2HNRNPC
A3SSWDR46ENSG00000227057.3chr6-3325574133255836332557413325580333255924332562470.167000.000000.00000longerK562AQR
A3SSWDR46ENSG00000227057.3chr6-3324754033247724332475403324763633248204332483650.079000.000000.00000longerK562AQR
A3SSWDR46ENSG00000227057.3chr6-3325591033256042332559103325601233256134332562310.056000.000000.00001longerK562AQR
A3SSWDR46ENSG00000227057.3chr6-3324820433248365332482043324829933248450332487640.108000.000020.00021longerK562AQR
A3SSWDR46ENSG00000227057.3chr6-3325486733255058332548673325500333255131332552820.101000.000000.00000longerK562AQR
A3SSWDR46ENSG00000227057.3chr6-3325613433256315332561343325624733256390332564710.200000.000000.00000longerK562AQR
A5SSWDR46ENSG00000227057.3chr6-3325536833255495332553903325549533255131332552820.051000.000010.00034longerK562AQR
RIWDR46ENSG00000227057.3chr6-3324820433248764332482043324829933248450332487640.151000.000580.00457includedK562PUS1
RIWDR46ENSG00000227057.3chr6-3325592433256247332559243325601233256134332562470.080000.000200.00174includedK562PUS1
RIWDR46ENSG00000227057.3chr6-3324820433248764332482043324829933248450332487640.099000.008950.07907includedHepG2SF3A3
RIWDR46ENSG00000227057.3chr6-3324688433247387332468843324715133247273332473870.217000.000010.00049includedK562HNRNPC
RIWDR46ENSG00000227057.3chr6-3324688433247387332468843324715133247273332473870.110000.000080.01732includedK562PCBP1
RIWDR46ENSG00000227057.3chr6-3324820433248764332482043324829933248450332487640.087000.000940.03467includedHepG2TIA1
RIWDR46ENSG00000227057.3chr6-332482043324876433248204332482993324845033248764-0.083000.005130.08609excludedK562SRSF1
RIWDR46ENSG00000227057.3chr6-3324688433247387332468843324715133247273332473870.205000.000000.00000includedK562PRPF8
RIWDR46ENSG00000227057.3chr6-3325592433256247332559243325601233256134332562470.074000.000090.00191includedK562PRPF8
RIWDR46ENSG00000227057.3chr6-3324820433248764332482043324829933248450332487640.158000.000000.00008includedHepG2IGF2BP3
RIWDR46ENSG00000227057.3chr6-3324688433247387332468843324715133247273332473870.118000.000000.00011includedHepG2PCBP1
RIWDR46ENSG00000227057.3chr6-3324820433248764332482043324829933248450332487640.087000.000780.01296includedHepG2PCBP1
RIWDR46ENSG00000227057.3chr6-3324820433248764332482043324829933248450332487640.104000.000070.00279includedHepG2SRSF1
RIWDR46ENSG00000227057.3chr6-3324820433248764332482043324829933248450332487640.098000.001230.01560includedHepG2QKI
RIWDR46ENSG00000227057.3chr6-3325592433256247332559243325601233256134332562470.054000.002900.05410includedK562RBM22
RIWDR46ENSG00000227057.3chr6-3324820433248764332482043324829933248450332487640.109000.000920.01047includedK562AKAP8L
RIWDR46ENSG00000227057.3chr6-3324820433248764332482043324829933248450332487640.153000.000010.00021includedHepG2TAF15
RIWDR46ENSG00000227057.3chr6-3324820433248764332482043324829933248450332487640.135000.000140.00238includedK562RBM15
RIWDR46ENSG00000227057.3chr6-3324820433248764332482043324829933248450332487640.143000.000010.00042includedHepG2G3BP1
RIWDR46ENSG00000227057.3chr6-3324688433247387332468843324715133247273332473870.073000.000170.00617includedHepG2KHSRP
RIWDR46ENSG00000227057.3chr6-3324820433248764332482043324829933248450332487640.151000.000040.00218includedHepG2KHSRP
RIWDR46ENSG00000227057.3chr6-3324820433248764332482043324829933248450332487640.090000.000760.00728includedHepG2SF3B4
RIWDR46ENSG00000227057.3chr6-3324820433248764332482043324829933248450332487640.157000.000010.00020includedHepG2RBM22
RIWDR46ENSG00000227057.3chr6-3324688433247387332468843324715133247273332473870.092000.000300.00764includedHepG2SRSF9
RIWDR46ENSG00000227057.3chr6-3324820433248764332482043324829933248450332487640.118000.000060.00121includedHepG2HNRNPK
RIWDR46ENSG00000227057.3chr6-3324820433248764332482043324829933248450332487640.115000.000010.00099includedHepG2PTBP1
RIWDR46ENSG00000227057.3chr6-3324688433247387332468843324715133247273332473870.119000.000740.01122includedK562UTP18
RIWDR46ENSG00000227057.3chr6-3324820433248764332482043324829933248450332487640.095000.011290.09737includedK562UTP18
RIWDR46ENSG00000227057.3chr6-3324688433247387332468843324715133247273332473870.168000.000000.00001includedK562EFTUD2
RIWDR46ENSG00000227057.3chr6-3325592433256247332559243325601233256134332562470.095000.000010.00017includedK562EFTUD2
RIWDR46ENSG00000227057.3chr6-3325592433256247332559243325601233256134332562470.115000.000000.00000includedK562AQR
RIWDR46ENSG00000227057.3chr6-3324820433248764332482043324829933248450332487640.142000.000000.00000includedK562AQR
RIWDR46ENSG00000227057.3chr6-3324688433247387332468843324715133247273332473870.374000.000000.00000includedK562AQR
RIWDR46ENSG00000227057.3chr6-3324820433248764332482043324829933248450332487640.121000.003530.09341includedHepG2XRN2
RIWDR46ENSG00000227057.3chr6-3324688433247387332468843324715133247273332473870.070000.003130.05237includedK562PTBP1
RIWDR46ENSG00000227057.3chr6-3324688433247387332468843324715133247273332473870.104000.000010.00022includedK562FXR1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for WDR46 is not avaliable on ENCORE database.