USP5

General Information

Gene Name       : USP5
Gene ID             : ENSG00000111667.13
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: USP5)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878USP5ENSG00000111667.1321.3759.5840.48ENCSR000AEF
HepG2USP5ENSG00000111667.1357.0443.7250.38ENCSR985KAT
K562USP5ENSG00000111667.1352.5861.3956.98ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for USP5 is not avaliable on ENCORE database.



Proteins bound to RNA
  • USP5 RNA is bound by 11 proteins.  







eCLIP assay for USP5 is not avaliable on ENCORE database.





11 proteins are bound to USP5 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr1269755796975631+3'-UTR5.074888.73200HepG2UPF1
chr1269753466975396+3'-UTR4.709315.07478HepG2U2AF2
chr1269755266975581+3'-UTR3.349953.12151HepG2SUB1
chr1269753226975408+3'-UTR5.9890016.92103HepG2UPF1
chr1269754046975470+3'-UTR5.620089.60749K562UPF1
chr1269753476975404+3'-UTR4.728888.27548K562UPF1
chr1269754866975579+3'-UTR5.8976316.16986HepG2UPF1
chr1269756906975758+3'-UTR4.192966.94394HepG2AKAP1
chr1269755816975698+3'-UTR4.441818.97449HepG2SUB1
chr1269755236975625+3'-UTR4.7261020.76727K562UPF1
chr1269755626975690+3'-UTR4.4287710.22552HepG2AKAP1
chr1269756256975695+3'-UTR5.8463925.37700K562UPF1
chr1269752716975339+3'-UTR3.212083.27165HepG2RBFOX2
chr1269754086975466+3'-UTR4.7527213.32127HepG2UPF1
chr1269755916975716+3'-UTR3.705613.29045K562AKAP1
chr1269756316975723+3'-UTR4.6396112.18470HepG2UPF1
chr1269752796975465+3'-UTR4.3674512.01845HepG2AKAP1
chr1269757146975755+3'-UTR4.743624.97123HepG2PCBP2
chr1269756956975761+3'-UTR6.6170123.84312K562UPF1
chr1269613116961456+5'-UTR,CDS,intron-Proximal3.169287.23254K562DDX3X
chr1269613256961382+5'-UTR,CDS4.220583.71613K562UCHL5
chr1269649396965037+CDS,intron-Proximal3.331974.71929HepG2PRPF8
chr1269646326964686+CDS3.784403.01531K562YBX3
chr1269676016967672+CDS,intron-Distal3.321644.68592HepG2PPIG
chr1269652546965314+CDS,intron-Proximal3.418467.09278HepG2PPIG
chr1269728966972974+intron-Proximal4.667316.36553HepG2RBFOX2
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for USP5 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for USP5 is not available on ENCORE database.

  • 78 RBPs can affect the levels of USP5.  








The Knockdown/knockout RNA-Seq assay for USP5 is not available on ENCORE database.





78 RBPs can affect the gene expression of USP5 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
USP5ENSG00000111667.92133.456401566.132000.445909.248008.26930HepG2ACO1
USP5ENSG00000111667.93468.852302051.098700.758008.870607.97770HepG2AKAP1
USP5ENSG00000111667.92612.132602239.872100.221702.552501.88870HepG2AUH
USP5ENSG00000111667.91051.535001372.12920-0.383902.873501.95540HepG2BCLAF1
USP5ENSG00000111667.9631.045601347.17680-1.0941019.5508018.17680HepG2BOP1
USP5ENSG00000111667.92080.563601612.324700.367702.911902.11840HepG2CIRBP
USP5ENSG00000111667.9788.340701236.77500-0.649707.245306.17540HepG2CPSF6
USP5ENSG00000111667.9840.908301195.39670-0.507505.588204.28780HepG2DDX24
USP5ENSG00000111667.9845.445001176.07190-0.476204.082702.40800HepG2DDX28
USP5ENSG00000111667.9778.015001124.82580-0.531803.644402.36290HepG2AGO1
USP5ENSG00000111667.91305.442801622.37540-0.313602.014601.49910HepG2EIF2S1
USP5ENSG00000111667.91587.957302083.29200-0.391703.482202.55940HepG2EIF4G1
USP5ENSG00000111667.91570.075801995.60340-0.346002.618701.82510HepG2EIF4G2
USP5ENSG00000111667.91625.437901940.56710-0.255602.520201.62320HepG2HNRNPA2B1
USP5ENSG00000111667.92078.189401699.969800.289702.107101.49210HepG2HNRNPK
USP5ENSG00000111667.91184.528601431.63310-0.273303.546602.39150HepG2KIF1C
USP5ENSG00000111667.9996.244401364.54470-0.453802.206901.34750HepG2MTPAP
USP5ENSG00000111667.9403.688301186.33550-1.5552030.9081028.84590HepG2NSUN2
USP5ENSG00000111667.91373.242401766.18600-0.363105.276404.48130HepG2PCBP1
USP5ENSG00000111667.9912.259601122.89470-0.299702.762802.02620HepG2PPIL4
USP5ENSG00000111667.91209.439301797.20080-0.5714011.3175010.35770HepG2PTBP1
USP5ENSG00000111667.9830.358701595.20510-0.9419029.8957028.26420HepG2PUS1
USP5ENSG00000111667.91651.625501946.32640-0.236902.088001.53350HepG2QKI
USP5ENSG00000111667.9846.167801226.20400-0.535202.556201.87800HepG2RAVER1
USP5ENSG00000111667.91235.011101766.44900-0.516306.491405.49850HepG2RBM25
USP5ENSG00000111667.9954.261301530.31010-0.681408.632906.87600HepG2RBM27
USP5ENSG00000111667.91319.898001846.96040-0.484705.133804.24170HepG2RPLP0
USP5ENSG00000111667.9859.806701184.52880-0.462203.514302.64260HepG2RRP9
USP5ENSG00000111667.92355.114601745.737100.431902.796602.11920HepG2SF3A3
USP5ENSG00000111667.91029.041201324.26640-0.363902.819202.10580HepG2SF3B1
USP5ENSG00000111667.91415.594801871.04530-0.402406.322705.48950HepG2SF3B4
USP5ENSG00000111667.91553.186101916.64260-0.303402.654801.96510HepG2SLBP
USP5ENSG00000111667.91586.309201307.420200.278904.010303.25870HepG2SMN1
USP5ENSG00000111667.91087.759101473.48240-0.437902.265201.56140HepG2SNRNP70
USP5ENSG00000111667.92159.701702427.72040-0.168801.996701.55010HepG2SRFBP1
USP5ENSG00000111667.92544.584801952.995900.381607.107206.43230HepG2SRSF1
USP5ENSG00000111667.91416.938801684.47620-0.249502.721502.03080HepG2SRSF7
USP5ENSG00000111667.9408.68190676.77250-0.727705.501803.89820HepG2STIP1
USP5ENSG00000111667.9785.148101146.02280-0.545603.101301.82320HepG2SUB1
USP5ENSG00000111667.92621.486502244.315900.224002.305101.72730HepG2SUCLG1
USP5ENSG00000111667.91195.389201545.70730-0.370802.781502.10330HepG2SUPV3L1
USP5ENSG00000111667.91339.983801755.51120-0.389704.814404.10740HepG2TAF15
USP5ENSG00000111667.9958.421501304.10640-0.444303.863903.02280HepG2TARDBP
USP5ENSG00000111667.91139.971501612.98830-0.500706.465405.19310HepG2TIA1
USP5ENSG00000111667.91055.408701234.26680-0.225902.063601.56320HepG2TRIM56
USP5ENSG00000111667.91275.579601555.52380-0.286201.838601.31560HepG2U2AF1
USP5ENSG00000111667.9601.70650913.01890-0.601605.701904.60300HepG2UCHL5
USP5ENSG00000111667.9902.265501548.20140-0.7790020.4303018.87810HepG2UPF1
USP5ENSG00000111667.92727.462601702.725900.6796025.9546024.70940HepG2ZNF622
USP5ENSG00000111667.91884.625001574.662900.259102.978302.39250K562AGGF1
USP5ENSG00000111667.91201.319002234.26830-0.8952015.1472013.92500K562AQR
USP5ENSG00000111667.9509.59750911.89200-0.839509.477707.80990K562BOP1
USP5ENSG00000111667.91513.070401881.85510-0.314703.155301.88400K562CCDC124
USP5ENSG00000111667.91272.873101985.45860-0.641403.217302.05820K562CNOT7
USP5ENSG00000111667.9710.40140969.59770-0.448804.062203.11220K562CPSF6
USP5ENSG00000111667.92795.648103476.45410-0.314403.076602.04930K562CELF1
USP5ENSG00000111667.92360.255502029.463200.217702.080701.50260K562DDX47
USP5ENSG00000111667.91113.34440714.891500.639008.737707.32700K562EIF3G
USP5ENSG00000111667.9696.350901064.44980-0.612205.406103.73640K562FKBP4
USP5ENSG00000111667.9706.80230986.55260-0.481104.009002.97530K562FMR1
USP5ENSG00000111667.9653.31130836.19660-0.356102.107001.31530K562FTO
USP5ENSG00000111667.91628.478101165.104700.483007.466506.53680K562FXR1
USP5ENSG00000111667.9177.47850599.37000-1.755806.528105.34010K562G3BP2
USP5ENSG00000111667.92295.397902762.41020-0.267202.173901.49840K562GRSF1
USP5ENSG00000111667.91564.744801995.39120-0.350703.619002.38590K562HNRNPA1
USP5ENSG00000111667.9741.105501226.21890-0.726509.999808.92220K562HNRNPC
USP5ENSG00000111667.91897.384602209.78700-0.219902.088401.31350K562HNRNPU
USP5ENSG00000111667.9460.36820790.46280-0.779906.054804.61320K562KRR1
USP5ENSG00000111667.92376.207403014.35260-0.343202.676201.56640K562MSI2
USP5ENSG00000111667.91453.718901752.37040-0.269603.282502.40520K562MTPAP
USP5ENSG00000111667.9966.804101947.08450-1.0100044.6344042.25980K562NSUN2
USP5ENSG00000111667.91053.876302118.26740-1.0072015.8981013.95540K562PCBP3
USP5ENSG00000111667.9937.995801624.77540-0.7926014.4955012.72490K562POLR2G
USP5ENSG00000111667.92646.566403281.33880-0.310202.584201.55360K562PUM1
USP5ENSG00000111667.91134.927801625.03880-0.517904.991304.28940K562PUS1
USP5ENSG00000111667.91055.23100738.442100.514902.432401.50060K562RPS3
USP5ENSG00000111667.91833.675101447.739000.340803.163602.00600K562SAFB
USP5ENSG00000111667.9606.41990880.41050-0.537903.815402.66320K562SF3B1
USP5ENSG00000111667.9828.486601076.28630-0.377502.844701.56470K562SLBP
USP5ENSG00000111667.9894.467901769.75220-0.984404.952702.77060K562STIP1
USP5ENSG00000111667.92026.286301629.703000.314103.274202.38160K562SYNCRIP
USP5ENSG00000111667.91627.728001103.363000.560906.024704.95230K562TARDBP
USP5ENSG00000111667.91401.984301064.359800.397403.907602.91210K562TIA1
USP5ENSG00000111667.91370.999901044.828700.391902.640501.57780K562TRA2A
USP5ENSG00000111667.92128.901802579.35780-0.276903.386701.97270K562TROVE2
USP5ENSG00000111667.9287.61300580.19780-1.012403.490102.23060K562U2AF1
USP5ENSG00000111667.9236.92420599.47530-1.339306.530505.30310K562U2AF2
USP5ENSG00000111667.9893.746601292.22330-0.531905.026603.60960K562UCHL5
USP5ENSG00000111667.91694.992002064.53150-0.284504.014703.16380K562UPF1
USP5ENSG00000111667.91343.596001766.56000-0.394804.224703.13450K562WDR3
USP5ENSG00000111667.91862.889902517.04330-0.434204.896703.69710K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for USP5 is not available on ENCORE database.





11 RBPs can affect the splicing of USP5 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEUSP5ENSG00000111667.9chr12+697060669707816970116697027069723496972541-0.249000.000010.00035excludedHepG2U2AF1
SEUSP5ENSG00000111667.9chr12+697060669707816970116697027069723496972541-0.421000.000000.00000excludedHepG2U2AF2
SEUSP5ENSG00000111667.9chr12+696546869657006965180696531469658706966055-0.060000.002150.02333excludedK562AQR
SEUSP5ENSG00000111667.9chr12+697161469717226970580697078169723496972541-0.077000.000580.00769excludedK562AQR
A3SSUSP5ENSG00000111667.9chr12+6975111697526869751476975268697432769744120.109000.000000.00000longerK562AQR
A3SSUSP5ENSG00000111667.9chr12+6970088697027069701166970270696952969696550.051000.000440.00336longerK562AQR
A3SSUSP5ENSG00000111667.9chr12+6972308697254169723496972541697161469717220.087000.000040.00036longerK562AQR
A5SSUSP5ENSG00000111667.9chr12+6972349697254169723496972472697299369731370.139000.000000.00063longerHepG2SRSF1
A5SSUSP5ENSG00000111667.9chr12+6972349697254169723496972472697299369731370.330000.000000.00000longerK562PTBP1
A5SSUSP5ENSG00000111667.9chr12+6972349697254169723496972472697299369731370.120000.000020.00814longerK562HNRNPU
A5SSUSP5ENSG00000111667.9chr12+6972349697254169723496972472697299369731370.201000.000760.04484longerK562SRSF1
A5SSUSP5ENSG00000111667.9chr12+6972349697254169723496972472697299369731370.256000.000000.00000longerHepG2PTBP1
RIUSP5ENSG00000111667.9chr12+6972993697335969729936973137697321369733590.068000.001140.01625includedK562PRPF8
RIUSP5ENSG00000111667.9chr12+6972993697335969729936973137697321369733590.051000.000580.00766includedHepG2TAF15
RIUSP5ENSG00000111667.9chr12+6972993697335969729936973137697321369733590.084000.000150.00255includedHepG2RBM22
RIUSP5ENSG00000111667.9chr12+6972993697335969729936973137697321369733590.069000.000020.00102includedHepG2SRSF9
RIUSP5ENSG00000111667.9chr12+6972993697335969729936973137697321369733590.051000.000740.02020includedHepG2PTBP1
RIUSP5ENSG00000111667.9chr12+6972993697335969729936973137697321369733590.081000.000130.00220includedK562EFTUD2
RIUSP5ENSG00000111667.9chr12+6972993697335969729936973137697321369733590.243000.000010.00006includedK562AQR
MXEUSP5ENSG00000111667.9chr12+69706066970781697163369717226970116697027069723086972541-0.092000.000020.000312includedK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for USP5 is not avaliable on ENCORE database.