TMEM14C

General Information

Gene Name       : TMEM14C
Gene ID             : ENSG00000111843.13
Essential Gene : No

Functions

Localization

Domains (AlphaFold: TMEM14C)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878TMEM14CENSG00000111843.1362.0659.3560.70ENCSR000AEF
HepG2TMEM14CENSG00000111843.1378.49136.13107.31ENCSR985KAT
K562TMEM14CENSG00000111843.13150.87177.12164.00ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for TMEM14C is not avaliable on ENCORE database.



Proteins bound to RNA
  • TMEM14C RNA is bound by 18 proteins.  







eCLIP assay for TMEM14C is not avaliable on ENCORE database.





18 proteins are bound to TMEM14C RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr61073114010731238+3'-UTR3.079775.30319HepG2UPF1
chr61073092710730988+3'-UTR3.850596.96561K562IGF2BP1
chr61073117710731200+3'-UTR3.1281222.20801K562PUM2
chr61073115410731242+3'-UTR3.6313426.28286K562PABPC4
chr61073114210731239+3'-UTR3.6002316.47594HepG2LARP4
chr61073114810731248+3'-UTR3.9006627.13060K562UPF1
chr61073092810730948+3'-UTR4.359289.57155K562YBX3
chr61073112410731231+3'-UTR4.8795212.77284HepG2SUB1
chr61073108310731126+3'-UTR6.25616400.00000K562PUM2
chr61073087710730927+3'-UTR,CDS3.722265.73713K562IGF2BP1
chr61073107010731130+3'-UTR3.7366619.31390K562YBX3
chr61073112910731147+3'-UTR6.51742400.00000K562PUM2
chr61073119710731249+3'-UTR3.689717.95235K562IGF2BP1
chr61073114710731177+3'-UTR5.02567400.00000K562PUM2
chr61073087710730942+3'-UTR,CDS3.355284.40956HepG2SUB1
chr61073096410731029+3'-UTR3.9034810.78852HepG2LARP4
chr61073101510731088+3'-UTR3.177333.62686HepG2LSM11
chr61073113010731145+3'-UTR3.7102812.65277K562YBX3
chr61072345510723475+5'-UTR,intron-Proximal4.175656.49041HepG2RPS3
chr61072474110724820+5'-UTR,intron-Distal,intron-Proximal4.308214.57682HepG2SF3B4
chr61072344010723475+5'-UTR,intron-Proximal5.0567411.47218K562GEMIN5
chr61072480110724820+5'-UTR,intron-Distal,intron-Proximal4.7317949.45986K562DDX3X
chr61072480110724865+5'-UTR,CDS,intron-Distal,intron-Proximal4.161737.33270K562DROSHA
chr61072342110723475+5'-UTR,intron-Proximal4.9513231.94504HepG2DDX3X
chr61072475910724856+5'-UTR,CDS,intron-Distal,intron-Proximal3.801575.56912HepG2AQR
chr61072346310723470+5'-UTR3.177877.43928K562YBX3
chr61072482010724850+5'-UTR,CDS,intron-Distal4.5392841.51079K562DDX3X
chr61072345910723475+5'-UTR,intron-Proximal4.8235210.22224K562RPS3
chr61072341310723443+5'-UTR3.0053811.00854K562YBX3
chr61072342310723474+5'-UTR4.159403.24327K562EIF3G
chr61072480510724847+5'-UTR,intron-Distal3.843196.32861K562GEMIN5
chr61072347110723474+5'-UTR4.4455133.29545K562DDX3X
chr61072340210723440+5'-UTR5.6477736.54748K562DDX3X
chr61072480110724832+5'-UTR,intron-Distal,intron-Proximal4.072277.86535K562RPS3
chr61072347010723474+5'-UTR3.408187.65762K562YBX3
chr61072346210723471+5'-UTR4.6502844.28775K562DDX3X
chr61072336110723402+5'-UTR4.1585510.43313HepG2DDX3X
chr61072479910724843+5'-UTR,intron-Distal,intron-Proximal3.9803433.47459HepG2DDX3X
chr61072344010723462+5'-UTR4.7418943.49370K562DDX3X
chr61072480210724821+5'-UTR,intron-Distal,intron-Proximal5.760627.96752HepG2RPS3
chr61072887810728909+CDS4.958789.52210K562SND1
chr61072521510725256+CDS,intron-Distal3.538485.73494K562GEMIN5
chr61072522110725247+CDS,intron-Distal4.227207.56262K562RPS3
chr61072521310725264+CDS,intron-Distal3.856855.60176HepG2SUB1
chr61072887210728886+CDS,intron-Proximal6.157245.98137K562RPS3
chr61072525710725271+CDS,intron-Distal,intron-Proximal3.810655.18795HepG2RPS3
chr61072486510724913+CDS,intron-Distal,intron-Proximal4.078858.79285K562AQR
chr61072891810728960+CDS4.020598.65614K562SND1
chr61072616210726211+CDS3.8039615.24935HepG2RPS3
chr61072484710724907+CDS,intron-Distal,intron-Proximal3.049093.13980HepG2PRPF8
chr61072613910726162+CDS,intron-Proximal3.971278.63182HepG2RPS3
chr61072519510725248+CDS,intron-Distal3.1360217.78270K562DDX3X
chr61072447410724555+intron-Distal4.172843.05187HepG2QKI
chr61072624110726283+intron-Proximal4.681374.48002K562AQR
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for TMEM14C is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for TMEM14C is not available on ENCORE database.

  • 83 RBPs can affect the levels of TMEM14C.  








The Knockdown/knockout RNA-Seq assay for TMEM14C is not available on ENCORE database.





83 RBPs can affect the gene expression of TMEM14C :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
TMEM14CENSG00000111843.91612.057301225.918700.394906.474105.62390HepG2ACO1
TMEM14CENSG00000111843.9578.524401217.85100-1.0739013.5675011.40210HepG2BCCIP
TMEM14CENSG00000111843.9910.656001225.62720-0.428506.804005.84430HepG2CKAP4
TMEM14CENSG00000111843.92258.276601792.151400.333402.420401.81190HepG2CELF1
TMEM14CENSG00000111843.9745.68850983.20880-0.398902.619401.49390HepG2DDX1
TMEM14CENSG00000111843.91134.878101887.73150-0.734108.880707.85680HepG2EIF2S1
TMEM14CENSG00000111843.91544.264702086.12780-0.433903.214002.52600HepG2EIF4A3
TMEM14CENSG00000111843.91404.770102031.20960-0.532003.638702.85540HepG2EIF4B
TMEM14CENSG00000111843.91893.166402332.91910-0.301303.886803.19470HepG2ETF1
TMEM14CENSG00000111843.9864.882001115.19650-0.366702.893002.08960HepG2FUBP3
TMEM14CENSG00000111843.91090.423902104.92870-0.9489014.6756013.21430HepG2FXR1
TMEM14CENSG00000111843.91552.199001952.57050-0.331102.145001.55680HepG2G3BP1
TMEM14CENSG00000111843.91568.813102072.98170-0.402003.306002.32600HepG2G3BP2
TMEM14CENSG00000111843.91268.358501977.29360-0.640608.103206.95730HepG2HNRNPK
TMEM14CENSG00000111843.9732.074701075.47660-0.554903.524702.84880HepG2HNRNPU
TMEM14CENSG00000111843.91334.250201984.72400-0.572905.832704.88890HepG2IGF2BP2
TMEM14CENSG00000111843.9823.198501098.57320-0.416303.113902.34010HepG2ILF2
TMEM14CENSG00000111843.91093.747301996.33280-0.868109.168307.24360HepG2KHSRP
TMEM14CENSG00000111843.9570.922301247.04520-1.1271019.4643016.59800HepG2LIN28B
TMEM14CENSG00000111843.91449.317802105.66410-0.538905.165004.27580HepG2MAGOH
TMEM14CENSG00000111843.91682.810202117.43080-0.331402.082201.53000HepG2MATR3
TMEM14CENSG00000111843.91029.43430804.199600.356102.817402.00160HepG2MSI2
TMEM14CENSG00000111843.9424.97000637.41910-0.584902.871701.88340HepG2MTPAP
TMEM14CENSG00000111843.91690.219702167.29320-0.358702.552101.94200HepG2NCBP2
TMEM14CENSG00000111843.91597.271101910.86310-0.258602.507101.78370HepG2NOL12
TMEM14CENSG00000111843.91313.524701930.04710-0.555205.376404.38050HepG2PABPC4
TMEM14CENSG00000111843.91316.876301961.70040-0.575005.974105.13570HepG2PCBP1
TMEM14CENSG00000111843.9654.14960999.71580-0.611903.484401.77840HepG2PNPT1
TMEM14CENSG00000111843.9764.00880959.24880-0.328302.050001.40700HepG2PPIL4
TMEM14CENSG00000111843.91444.433301995.98010-0.466605.679804.95230HepG2PTBP1
TMEM14CENSG00000111843.91058.518101824.07090-0.7851013.4070012.22670HepG2PUF60
TMEM14CENSG00000111843.91607.979801934.91070-0.267002.493301.85610HepG2PUM2
TMEM14CENSG00000111843.91512.569302161.95870-0.515305.838804.97910HepG2QKI
TMEM14CENSG00000111843.92900.053401949.906900.5726012.3799011.44460HepG2RBM22
TMEM14CENSG00000111843.91612.924901962.01710-0.282702.598901.94240HepG2RBM25
TMEM14CENSG00000111843.91698.013902221.43670-0.387604.282203.63560HepG2NELFE
TMEM14CENSG00000111843.91304.448502068.78040-0.6653010.079709.01720HepG2RECQL
TMEM14CENSG00000111843.9537.51110676.34200-0.331502.167101.61610HepG2RPS19
TMEM14CENSG00000111843.9668.76720913.62250-0.450102.908902.10550HepG2RRP9
TMEM14CENSG00000111843.91495.653602078.29420-0.474605.630104.83700HepG2SF3B4
TMEM14CENSG00000111843.91932.070802202.38030-0.188901.935101.49360HepG2SRFBP1
TMEM14CENSG00000111843.91491.654702169.19880-0.540206.976206.30800HepG2SRSF1
TMEM14CENSG00000111843.91580.340401800.98290-0.188501.833101.30930HepG2SRSF5
TMEM14CENSG00000111843.9770.00400926.07520-0.266302.053501.44390HepG2SRSF7
TMEM14CENSG00000111843.91331.988201764.68100-0.405804.453103.78380HepG2SRSF9
TMEM14CENSG00000111843.91560.807302048.23200-0.392107.491206.54850HepG2SUCLG1
TMEM14CENSG00000111843.91591.366101191.982300.416802.789102.10980HepG2SUPV3L1
TMEM14CENSG00000111843.91398.444601791.59990-0.357403.565402.62120HepG2TIA1
TMEM14CENSG00000111843.9731.944401045.23440-0.514003.592703.03850HepG2TIAL1
TMEM14CENSG00000111843.9766.848001054.35480-0.459303.669203.03900HepG2TRIM56
TMEM14CENSG00000111843.9369.50940849.99110-1.2018017.0618015.44820HepG2U2AF1
TMEM14CENSG00000111843.9168.20490617.11350-1.875307.898806.14650HepG2U2AF2
TMEM14CENSG00000111843.91480.714601886.21140-0.349202.236101.48770HepG2UBE2L3
TMEM14CENSG00000111843.9970.61520704.118400.463003.403802.56650HepG2UCHL5
TMEM14CENSG00000111843.91050.019001417.97340-0.433404.313802.80260K562AARS
TMEM14CENSG00000111843.92711.692902024.595800.421507.806506.92210K562AGGF1
TMEM14CENSG00000111843.92796.898402224.544000.330202.876901.86990K562AKAP8
TMEM14CENSG00000111843.92662.854702106.639200.337902.965902.28890K562AKAP8L
TMEM14CENSG00000111843.92685.398103993.64020-0.572608.437407.50290K562AQR
TMEM14CENSG00000111843.91471.756702379.19650-0.6929016.6809013.60660K562BCCIP
TMEM14CENSG00000111843.9566.92490787.32700-0.473803.784802.51380K562CCAR1
TMEM14CENSG00000111843.96224.868104806.470200.373005.381804.01730K562CELF1
TMEM14CENSG00000111843.91851.957802117.93590-0.193601.891101.33370K562DDX47
TMEM14CENSG00000111843.92669.530702267.173600.235602.351701.55350K562DKC1
TMEM14CENSG00000111843.92253.751801729.173100.382102.548701.32620K562EEF2
TMEM14CENSG00000111843.91293.381401670.69570-0.369303.027302.07090K562EFTUD2
TMEM14CENSG00000111843.92173.425102524.00730-0.215702.203201.55090K562EIF2S2
TMEM14CENSG00000111843.91293.888901788.76660-0.467303.576702.38420K562EIF3D
TMEM14CENSG00000111843.91614.859701950.38220-0.272302.075301.36030K562EIF4A3
TMEM14CENSG00000111843.92460.970501642.514200.583207.861206.35570K562FIP1L1
TMEM14CENSG00000111843.91538.350902028.31560-0.398905.846205.01460K562FXR1
TMEM14CENSG00000111843.91000.455001550.82510-0.632408.858907.84120K562HNRNPC
TMEM14CENSG00000111843.9777.688401385.20710-0.8328013.3764010.87450K562HNRNPF
TMEM14CENSG00000111843.92913.423202226.750000.387703.895402.95500K562HSPD1
TMEM14CENSG00000111843.92913.304802235.826700.381702.266101.52880K562KIF1C
TMEM14CENSG00000111843.9964.395801573.56640-0.706307.879705.22400K562LIN28B
TMEM14CENSG00000111843.91028.911101383.57910-0.427303.972902.05330K562LSM11
TMEM14CENSG00000111843.92075.230302514.19000-0.276802.390401.60640K562MAGOH
TMEM14CENSG00000111843.92282.246501755.577800.378402.202701.43610K562NAA15
TMEM14CENSG00000111843.92272.294401646.282900.464804.192302.51900K562NONO
TMEM14CENSG00000111843.92225.468801485.292100.583302.480501.55660K562PABPN1
TMEM14CENSG00000111843.91474.404402237.12450-0.601508.377906.63950K562PCBP2
TMEM14CENSG00000111843.92461.736101864.733200.400603.844202.85370K562PPIG
TMEM14CENSG00000111843.91048.566001390.56580-0.407303.773002.69390K562PSIP1
TMEM14CENSG00000111843.91617.419702442.64470-0.594709.737408.54620K562PTBP1
TMEM14CENSG00000111843.93369.759004264.83940-0.339803.348402.45180K562PUF60
TMEM14CENSG00000111843.93886.770304444.69260-0.193502.174001.32180K562PUM2
TMEM14CENSG00000111843.93533.866302089.526400.7580011.9475010.86710K562PUS1
TMEM14CENSG00000111843.92903.929302035.664900.512408.965007.92310K562RBM15
TMEM14CENSG00000111843.91794.822202283.27660-0.347302.765401.38940K562RBM34
TMEM14CENSG00000111843.92550.404201662.259400.617505.183603.35830K562RRP9
TMEM14CENSG00000111843.9837.059901101.95580-0.396702.448801.53810K562SF3B1
TMEM14CENSG00000111843.91585.845401983.08010-0.322503.404402.45290K562SF3B4
TMEM14CENSG00000111843.91835.883802261.27710-0.300702.399901.43220K562SRSF5
TMEM14CENSG00000111843.92032.054701700.843500.256603.104101.73280K562SSB
TMEM14CENSG00000111843.91896.499802337.77610-0.301803.003902.14500K562TIA1
TMEM14CENSG00000111843.91094.514001421.33310-0.377003.191302.15910K562TRIM56
TMEM14CENSG00000111843.91350.049901909.32860-0.500107.156905.87300K562U2AF2
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for TMEM14C is not available on ENCORE database.





11 RBPs can affect the splicing of TMEM14C :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SETMEM14CENSG00000111843.9chr6+107261391072624110723341107234741072887210728960-0.065000.000810.01750excludedK562SRSF1
SETMEM14CENSG00000111843.9chr6+107247881072486610723147107234741072519310725270-0.063000.000420.00981excludedHepG2U2AF1
SETMEM14CENSG00000111843.9chr6+107251931072527010723357107234741072613910726241-0.161000.000010.00059excludedHepG2HNRNPK
SETMEM14CENSG00000111843.9chr6+107251931072527010723357107234741072613910726241-0.143000.000750.05382excludedHepG2IGF2BP3
MXETMEM14CENSG00000111843.9chr6+1072613910726241107288721072896010725193107252701073084710731362-0.073000.002550.033412includedK562U2AF2
MXETMEM14CENSG00000111843.9chr6+1072613910726241107288721072896010723341107234741073084710730996-0.075000.005570.051882includedHepG2SFPQ
MXETMEM14CENSG00000111843.9chr6+1072613910726241107288721072896010725193107252701073084710731352-0.101000.002840.056862includedHepG2DDX55
MXETMEM14CENSG00000111843.9chr6+1072613910726241107288721072896010725193107252701073084710731362-0.097000.000060.013562includedK562AARS
MXETMEM14CENSG00000111843.9chr6+1072613910726241107288721072896010723341107234741073084710730996-0.079000.007660.083502includedHepG2HNRNPUL1
MXETMEM14CENSG00000111843.9chr6+1072613910726241107288721072896010725193107252701073084710731362-0.094000.000020.002472includedK562TAF15
MXETMEM14CENSG00000111843.9chr6+1072613910726241107288721072896010725193107252701073084710731362-0.051000.005740.093972includedK562PPIL4
MXETMEM14CENSG00000111843.9chr6+1072613910726241107288721072896010725193107252701073084710731362-0.091000.000120.007702includedK562DDX55

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for TMEM14C is not avaliable on ENCORE database.