REC8

General Information

Gene Name       : REC8
Gene ID             : ENSG00000100918.12
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: REC8)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878REC8ENSG00000100918.1212.4420.5916.52ENCSR000AEF
HepG2REC8ENSG00000100918.122.631.482.05ENCSR985KAT
K562REC8ENSG00000100918.120.610.570.59ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for REC8 is not avaliable on ENCORE database.



Proteins bound to RNA
  • REC8 RNA is bound by 7 proteins.  







eCLIP assay for REC8 is not avaliable on ENCORE database.





7 proteins are bound to REC8 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr142464160124641670+5'-UTR,intron-Proximal3.770098.05393HepG2U2AF2
chr142464161824641666+5'-UTR,intron-Proximal3.793193.43234HepG2U2AF1
chr142464655724646590+CDS,intron-Proximal4.176097.79455HepG2PPIG
chr142464665524646719+CDS,intron-Proximal3.459753.37120HepG2SF3B4
chr142464833024648339+CDS4.248083.05716HepG2PABPN1
chr142464801124648073+CDS4.348093.89860HepG2PABPN1
chr142464735124647421+CDS4.247107.79455HepG2PPIG
chr142464880024648848+CDS,intron-Proximal3.696334.78537HepG2PABPN1
chr142464605224646108+CDS3.103293.00343HepG2GRWD1
chr142464641824646429+CDS,intron-Proximal4.793566.16445HepG2PPIG
chr142464605824646111+CDS,intron-Proximal3.784874.77136HepG2PPIG
chr142464781224647873+CDS5.030805.56813HepG2PPIG
chr142464828924648336+CDS,intron-Proximal4.469376.36347HepG2PPIG
chr142464642524646475+CDS,intron-Proximal3.841466.86197HepG2PRPF8
chr142464860424648641+CDS3.551123.86355HepG2PPIG
chr142464828924648330+CDS,intron-Proximal3.297713.61282HepG2PABPN1
chr142464860124648664+CDS,intron-Proximal5.147525.90013HepG2PABPN1
chr142464667024646740+CDS,intron-Proximal3.832067.64107HepG2PPIG
chr142464634924646412+CDS,intron-Proximal3.802379.30518HepG2PPIG
chr142464661824646655+intron-Proximal5.031945.86025HepG2SF3B4
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for REC8 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for REC8 is not available on ENCORE database.

  • 90 RBPs can affect the levels of REC8.  








The Knockdown/knockout RNA-Seq assay for REC8 is not available on ENCORE database.





90 RBPs can affect the gene expression of REC8 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
REC8ENSG00000100918.874.04420161.77050-1.127504.523303.86480HepG2AKAP1
REC8ENSG00000100918.8321.91550138.363201.2181012.5810011.30380HepG2AUH
REC8ENSG00000100918.8204.3123077.923401.390507.130105.58700HepG2BCCIP
REC8ENSG00000100918.8132.5926067.711700.969403.422302.42570HepG2BCLAF1
REC8ENSG00000100918.8105.3414047.527701.148103.947803.24550HepG2BOP1
REC8ENSG00000100918.8277.74620106.016001.389409.347807.56090HepG2CCAR1
REC8ENSG00000100918.8108.28690267.63360-1.305406.831805.63020HepG2CNOT7
REC8ENSG00000100918.8206.18340110.119400.904804.407003.02850HepG2CPSF7
REC8ENSG00000100918.8148.7977085.796900.794302.906101.86240HepG2YBX3
REC8ENSG00000100918.8212.15050150.142500.498702.078901.50830HepG2CELF1
REC8ENSG00000100918.8297.41390161.480000.881007.314506.19260HepG2DAZAP1
REC8ENSG00000100918.8134.1748080.968000.728602.505001.85680HepG2DDX21
REC8ENSG00000100918.8255.59440154.961000.721903.438802.75080HepG2DDX3X
REC8ENSG00000100918.8218.8541076.613601.514208.503707.22870HepG2DDX55
REC8ENSG00000100918.8234.57370133.121600.817203.691202.98610HepG2DDX6
REC8ENSG00000100918.8145.2989084.248400.786203.362902.59280HepG2DNAJC21
REC8ENSG00000100918.8147.4175074.604700.982503.878802.55500HepG2AGO1
REC8ENSG00000100918.8419.70540127.966201.7135019.2014017.73870HepG2EIF2S1
REC8ENSG00000100918.8135.5273062.007601.128002.559201.68550HepG2EIF3D
REC8ENSG00000100918.8262.83880141.414400.894103.008202.34180HepG2EIF4A3
REC8ENSG00000100918.8340.38320152.581901.157502.023301.31940HepG2EIF4G2
REC8ENSG00000100918.8390.24170158.870701.2964015.2033013.97660HepG2ETF1
REC8ENSG00000100918.8133.9305077.187700.794902.968101.78630HepG2FASTKD2
REC8ENSG00000100918.8223.18600135.073100.724402.613101.86350HepG2FIP1L1
REC8ENSG00000100918.8106.7816043.710001.288502.986301.92990HepG2FTO
REC8ENSG00000100918.8174.2402090.073900.951803.809902.89590HepG2FUBP3
REC8ENSG00000100918.8267.41510132.361701.014506.339905.35400HepG2G3BP1
REC8ENSG00000100918.8200.09400112.359600.832503.675602.49570HepG2GNB2L1
REC8ENSG00000100918.8138.7172049.453301.487903.163502.48390HepG2GPKOW
REC8ENSG00000100918.8192.03760131.997500.540802.618501.66430HepG2HDGF
REC8ENSG00000100918.8237.24570148.385500.676903.574102.53140HepG2HNRNPA2B1
REC8ENSG00000100918.8186.4306094.607400.978504.534303.66210HepG2HNRNPC
REC8ENSG00000100918.8197.7688091.728201.108307.400306.29950HepG2HNRNPF
REC8ENSG00000100918.851.4567093.98200-0.869002.906102.28610HepG2HNRNPU
REC8ENSG00000100918.8189.3696090.325501.067906.209305.16770HepG2IGF2BP1
REC8ENSG00000100918.8524.58580134.540901.9630027.5447025.68140HepG2IGF2BP2
REC8ENSG00000100918.8167.1552095.999700.800004.435403.52690HepG2ILF2
REC8ENSG00000100918.8216.92810135.328700.680602.570401.60920HepG2KHSRP
REC8ENSG00000100918.8218.84990111.920300.967404.747203.65000HepG2LARP4
REC8ENSG00000100918.885.50700143.53830-0.747302.306801.72730HepG2MATR3
REC8ENSG00000100918.8171.49710109.274100.650102.248601.51550HepG2MSI2
REC8ENSG00000100918.8309.20300146.918101.073407.283606.27930HepG2NCBP2
REC8ENSG00000100918.8189.75520313.19390-0.722903.563001.92920HepG2NKRF
REC8ENSG00000100918.883.1405041.851300.990202.374301.67920HepG2NSUN2
REC8ENSG00000100918.8505.87590244.680101.047806.673005.25040HepG2PABPC1
REC8ENSG00000100918.8250.50220130.834100.937005.489804.48340HepG2PABPC4
REC8ENSG00000100918.8345.26400103.568501.7370024.5670023.05930HepG2PCBP1
REC8ENSG00000100918.8237.7015099.524301.255907.585605.95040HepG2PCBP2
REC8ENSG00000100918.8207.55660321.01340-0.629103.197901.31210HepG2PPIG
REC8ENSG00000100918.8247.1429059.108102.0638016.3918014.65310HepG2PRPF8
REC8ENSG00000100918.8257.95590152.838500.755004.067803.35990HepG2PUF60
REC8ENSG00000100918.8235.96700162.121400.541402.286001.67420HepG2PUM2
REC8ENSG00000100918.894.51530140.80890-0.575102.153401.59340HepG2PUS1
REC8ENSG00000100918.8125.7156062.179701.015503.336401.44100HepG2RBM14
REC8ENSG00000100918.8188.69930132.784100.506901.812301.36980HepG2RBM22
REC8ENSG00000100918.8273.99030103.580301.403309.333108.15070HepG2RBM25
REC8ENSG00000100918.8204.70030117.290900.803302.263501.76410HepG2NELFE
REC8ENSG00000100918.8206.03300109.281800.914704.554303.78970HepG2RECQL
REC8ENSG00000100918.8196.4503098.821800.991204.736803.87500HepG2RPLP0
REC8ENSG00000100918.8197.9079094.361301.068505.057703.80230HepG2RPS10
REC8ENSG00000100918.8185.59740122.404600.600402.244901.51990HepG2RPS2
REC8ENSG00000100918.8235.38380109.698601.101407.415106.52340HepG2SF3B4
REC8ENSG00000100918.8218.45590146.521600.576102.752402.05270HepG2SLBP
REC8ENSG00000100918.8116.8146051.974501.168203.539902.65150HepG2SNRNP70
REC8ENSG00000100918.8449.15110149.970701.5824024.1207023.02040HepG2SRFBP1
REC8ENSG00000100918.842.85400114.52170-1.418102.342501.89790HepG2SRSF1
REC8ENSG00000100918.8224.45340150.890200.572802.652302.03640HepG2SRSF5
REC8ENSG00000100918.8178.2788090.121800.984105.586904.65490HepG2SRSF7
REC8ENSG00000100918.8423.6494093.186702.1846043.2721041.60650HepG2SRSF9
REC8ENSG00000100918.8462.05110234.012400.981407.925305.97400HepG2STIP1
REC8ENSG00000100918.8214.7771076.269701.493607.446706.42420HepG2SUPV3L1
REC8ENSG00000100918.8102.2566046.015401.151903.394002.60070HepG2TARDBP
REC8ENSG00000100918.8232.8436094.576701.299708.320506.87700HepG2TIA1
REC8ENSG00000100918.8308.5165091.325101.7562012.6767011.74100HepG2TIAL1
REC8ENSG00000100918.8174.9773092.137100.925205.444204.70450HepG2TRIM56
REC8ENSG00000100918.8269.92200149.295500.854305.152403.91950HepG2TUFM
REC8ENSG00000100918.8266.45940158.013000.753803.041102.16560HepG2UBE2L3
REC8ENSG00000100918.8107.5824045.056201.255505.070404.03600HepG2UCHL5
REC8ENSG00000100918.8200.82990140.129000.519102.368901.71460HepG2UPF1
REC8ENSG00000100918.8160.2087069.844901.197604.523203.22070HepG2UPF2
REC8ENSG00000100918.884.50290135.28860-0.679002.354501.79210HepG2UTP3
REC8ENSG00000100918.8402.47200240.899000.740404.441103.04110HepG2XPO5
REC8ENSG00000100918.8253.5553075.079101.7557012.4407010.92730HepG2XRN2
REC8ENSG00000100918.8137.5729082.330300.740602.937702.24880HepG2ZC3H8
REC8ENSG00000100918.8242.40290154.114600.653304.136403.50450HepG2ZNF622
REC8ENSG00000100918.875.7536025.425101.575004.676903.47480K562EFTUD2
REC8ENSG00000100918.883.4654027.212201.616804.965803.53190K562EIF3D
REC8ENSG00000100918.858.9589027.895101.079602.140801.60730K562HNRNPC
REC8ENSG00000100918.816.1178040.61460-1.333302.472101.62780K562HNRNPU
REC8ENSG00000100918.861.0877029.591301.045602.693201.52290K562IGF2BP3
REC8ENSG00000100918.870.1252029.887001.230303.600502.05530K562PCBP1
REC8ENSG00000100918.859.0300027.202001.117602.483301.55900K562PCBP2
REC8ENSG00000100918.86.8812029.70410-2.109903.635102.88550K562PTBP1
REC8ENSG00000100918.8132.7159059.172001.165303.018101.39600K562RBM39
REC8ENSG00000100918.819.3039045.05080-1.222702.375001.61440K562SYNCRIP
REC8ENSG00000100918.879.5232029.470801.432004.769303.83200K562TARDBP
REC8ENSG00000100918.861.6931024.058001.358503.188502.17900K562TIAL1
REC8ENSG00000100918.8127.0714071.068700.838303.217602.27860K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for REC8 is not available on ENCORE database.





3 RBPs can affect the splicing of REC8 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
RIREC8ENSG00000100918.8chr14+2464781124648122246478112464787824647982246481220.417000.000440.00354includedK562PUS1
RIREC8ENSG00000100918.8chr14+2464781124648122246478112464787824647982246481220.430000.000030.00053includedK562AKAP8L
RIREC8ENSG00000100918.8chr14+2464781124648122246478112464787824647982246481220.363000.008110.07565includedK562UTP18

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for REC8 is not avaliable on ENCORE database.