MRPL18

General Information

Gene Name       : MRPL18
Gene ID             : ENSG00000112110.9
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: MRPL18)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878MRPL18ENSG00000112110.950.4953.6052.05ENCSR000AEF
HepG2MRPL18ENSG00000112110.9111.91146.93129.42ENCSR985KAT
K562MRPL18ENSG00000112110.9126.09132.10129.09ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for MRPL18 is not avaliable on ENCORE database.



Proteins bound to RNA
  • MRPL18 RNA is bound by 10 proteins.  







eCLIP assay for MRPL18 is not avaliable on ENCORE database.





10 proteins are bound to MRPL18 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr6160219151160219160+3'-UTR,CDS4.919947.06926K562PABPC4
chr6160219185160219233+3'-UTR6.36419400.00000K562PUM2
chr6160219296160219440+3'-UTR4.0566013.93535K562IGF2BP1
chr6160219183160219240+3'-UTR3.671394.75336K562PUM1
chr6160219282160219354+3'-UTR3.800957.63427HepG2SUB1
chr6160219171160219184+3'-UTR5.351516.34419K562PUM2
chr6160219160160219228+3'-UTR3.244237.68020K562PABPC4
chr6160219152160219171+3'-UTR6.240317.00172K562PUM2
chr6160211523160211580+5'-UTR,intron-Distal4.3775911.81272K562DDX3X
chr6160212092160212103+CDS4.3093321.94366K562YBX3
chr6160212025160212033+CDS4.043576.36816K562YBX3
chr6160211882160211996+CDS,intron-Proximal4.880245.58015HepG2AQR
chr6160212123160212275+CDS,intron-Distal,intron-Proximal4.285027.26133HepG2PRPF8
chr6160219083160219091+CDS,intron-Proximal3.200144.14323K562YBX3
chr6160218500160218528+CDS3.8021314.83162K562YBX3
chr6160218431160218473+CDS3.907173.43895HepG2LARP4
chr6160218528160218549+CDS4.3456020.65031K562YBX3
chr6160211992160212000+CDS3.815859.47757K562YBX3
chr6160212000160212025+CDS4.4472410.66391K562YBX3
chr6160212128160212150+CDS4.2086317.97646K562YBX3
chr6160211970160211989+CDS,intron-Proximal3.017747.31049K562DDX3X
chr6160211027160211068+intron-Distal3.532328.73886K562DDX3X
chr6160211034160211079+intron-Distal4.436754.66990HepG2DDX3X
chr6160211068160211092+intron-Distal4.3633210.93922K562DDX3X
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for MRPL18 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for MRPL18 is not available on ENCORE database.

  • 80 RBPs can affect the levels of MRPL18.  








The Knockdown/knockout RNA-Seq assay for MRPL18 is not available on ENCORE database.





80 RBPs can affect the gene expression of MRPL18 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
MRPL18ENSG00000112110.51025.30360715.455700.519003.827202.72900HepG2ABCF1
MRPL18ENSG00000112110.5882.56410681.538100.372804.141603.42610HepG2ACO1
MRPL18ENSG00000112110.51396.64160873.249300.677406.028805.27810HepG2AKAP1
MRPL18ENSG00000112110.5922.49290733.567100.330502.183501.64670HepG2BOP1
MRPL18ENSG00000112110.5493.46660664.33500-0.429003.334602.49780HepG2CALR
MRPL18ENSG00000112110.5904.39490686.462900.397702.644801.88720HepG2CIRBP
MRPL18ENSG00000112110.5830.72920681.389200.285802.670202.01370HepG2CKAP4
MRPL18ENSG00000112110.5442.57520673.44940-0.605604.915304.02130HepG2CPSF6
MRPL18ENSG00000112110.5964.892501178.14940-0.288103.198702.41120HepG2DAZAP1
MRPL18ENSG00000112110.5943.63010576.427800.711007.986406.89540HepG2DDX21
MRPL18ENSG00000112110.5825.28980652.047100.339803.046102.33950HepG2DKC1
MRPL18ENSG00000112110.5781.26370539.016100.535402.595901.70000HepG2EEF2
MRPL18ENSG00000112110.5633.22570449.433600.494503.468002.22110HepG2EFTUD2
MRPL18ENSG00000112110.5461.70640690.78410-0.581304.167803.44830HepG2EIF2S1
MRPL18ENSG00000112110.51154.74100763.396500.597004.861204.01790HepG2EIF4A3
MRPL18ENSG00000112110.5859.24520665.983800.367502.818501.97590HepG2EWSR1
MRPL18ENSG00000112110.5241.08000549.10360-1.1876010.384008.41230HepG2FASTKD2
MRPL18ENSG00000112110.5774.073501114.52500-0.525907.561606.45370HepG2HNRNPF
MRPL18ENSG00000112110.5670.470401073.17900-0.6786013.3089011.93440HepG2HNRNPL
MRPL18ENSG00000112110.5405.21190728.52150-0.846308.437207.40210HepG2HNRNPLL
MRPL18ENSG00000112110.5806.486301097.49430-0.444504.292903.40760HepG2IGF2BP1
MRPL18ENSG00000112110.5909.16010726.280500.323901.889701.32180HepG2IGF2BP2
MRPL18ENSG00000112110.5470.27180623.01080-0.405803.992102.77220HepG2KIF1C
MRPL18ENSG00000112110.51727.17490774.819501.1564017.1995015.73310HepG2MATR3
MRPL18ENSG00000112110.5433.61150743.02810-0.777004.954303.63280HepG2MTPAP
MRPL18ENSG00000112110.5913.045801168.25490-0.355603.347902.51010HepG2NOL12
MRPL18ENSG00000112110.5481.70040645.98390-0.423402.518001.80300HepG2NSUN2
MRPL18ENSG00000112110.5501.84140706.27860-0.493003.268702.48640HepG2PABPC4
MRPL18ENSG00000112110.5460.67860667.22480-0.534402.807701.76050HepG2PCBP2
MRPL18ENSG00000112110.5391.32440579.61660-0.566703.513302.69240HepG2PPIL4
MRPL18ENSG00000112110.5981.28710701.414300.484302.520101.35360HepG2PRPF6
MRPL18ENSG00000112110.5639.12290806.40470-0.335402.548901.94550HepG2QKI
MRPL18ENSG00000112110.5957.79920643.873000.572802.789102.08190HepG2RAVER1
MRPL18ENSG00000112110.51358.910301019.839500.414005.329304.66880HepG2RBM22
MRPL18ENSG00000112110.51651.548501200.535700.460003.950303.15750HepG2RPLP0
MRPL18ENSG00000112110.5535.16240425.767600.329801.920301.40000HepG2RPS19
MRPL18ENSG00000112110.51307.99410736.734500.828004.285203.43570HepG2SF3A3
MRPL18ENSG00000112110.5683.130701069.38090-0.6465011.9045010.62300HepG2SLBP
MRPL18ENSG00000112110.51411.93800809.156700.8031018.6502017.65060HepG2SRSF1
MRPL18ENSG00000112110.5215.07040775.91230-1.8511025.8159022.70130HepG2SRSF3
MRPL18ENSG00000112110.5832.361001094.96530-0.395604.477403.62470HepG2SRSF7
MRPL18ENSG00000112110.5533.77680658.29560-0.302502.428901.90470HepG2SRSF9
MRPL18ENSG00000112110.51372.727201000.142600.456707.452006.68990HepG2SSB
MRPL18ENSG00000112110.5500.50990710.12030-0.504703.790102.95720HepG2TARDBP
MRPL18ENSG00000112110.5530.57330668.28950-0.332902.253301.49670HepG2TIA1
MRPL18ENSG00000112110.5953.80650618.038800.625905.656804.77490HepG2U2AF1
MRPL18ENSG00000112110.5645.65870495.431900.382002.511101.78810HepG2UCHL5
MRPL18ENSG00000112110.5823.50990630.805500.384503.825003.13860HepG2UTP3
MRPL18ENSG00000112110.51767.812201327.717500.412906.613105.79060K562AGGF1
MRPL18ENSG00000112110.51795.906701381.549400.378303.550502.80700K562AKAP8L
MRPL18ENSG00000112110.5458.48270721.95980-0.655105.993804.28580K562CCAR1
MRPL18ENSG00000112110.5822.395201107.09570-0.428904.067303.11690K562CPSF6
MRPL18ENSG00000112110.5921.463501107.78910-0.265702.254301.31960K562CSTF2
MRPL18ENSG00000112110.5836.589501255.95540-0.586205.165202.87240K562DDX51
MRPL18ENSG00000112110.51829.179601486.651900.299003.479002.48070K562DKC1
MRPL18ENSG00000112110.5976.169801216.62400-0.317702.522301.31740K562EXOSC5
MRPL18ENSG00000112110.5571.306701018.14890-0.8336011.525808.35840K562FASTKD2
MRPL18ENSG00000112110.5894.000101126.38300-0.333402.248001.47390K562FMR1
MRPL18ENSG00000112110.5753.59440954.68480-0.341202.105801.31480K562FTO
MRPL18ENSG00000112110.51817.576401108.580900.7132015.8494014.51180K562FXR1
MRPL18ENSG00000112110.51417.834901732.44450-0.289102.529401.50210K562HNRNPA1
MRPL18ENSG00000112110.51211.520801541.77840-0.347803.159302.52720K562HNRNPC
MRPL18ENSG00000112110.5922.275501376.97900-0.578206.903305.02090K562HNRNPF
MRPL18ENSG00000112110.51666.003001168.670800.511404.362503.17660K562HNRNPM
MRPL18ENSG00000112110.5654.70550902.50530-0.463102.602501.70130K562KRR1
MRPL18ENSG00000112110.51189.289301493.51710-0.328602.724301.34900K562LARP7
MRPL18ENSG00000112110.51143.788301564.07340-0.451503.726101.96600K562LIN28B
MRPL18ENSG00000112110.51072.202101375.16870-0.359003.167101.49940K562LSM11
MRPL18ENSG00000112110.5801.777501031.76770-0.363802.836101.94700K562METAP2
MRPL18ENSG00000112110.51206.338401547.54310-0.359302.473901.68800K562PCBP3
MRPL18ENSG00000112110.51151.794301505.38430-0.386203.649401.97730K562PHF6
MRPL18ENSG00000112110.52071.199301612.947200.360703.014702.15440K562PPIG
MRPL18ENSG00000112110.51662.972101131.775600.555106.002604.89720K562PRPF8
MRPL18ENSG00000112110.5941.488201382.41290-0.554206.375804.91340K562PSIP1
MRPL18ENSG00000112110.54642.514103122.095000.572308.402006.97340K562PUF60
MRPL18ENSG00000112110.51961.421901370.124600.517505.509404.77520K562PUS1
MRPL18ENSG00000112110.51853.945301334.974400.473707.030506.11390K562RBM15
MRPL18ENSG00000112110.5756.419101261.49900-0.7379011.191709.16970K562RCC2
MRPL18ENSG00000112110.51431.348601152.935800.312002.004401.31480K562RPS19
MRPL18ENSG00000112110.5783.258501195.84390-0.610506.787704.97560K562SRFBP1
MRPL18ENSG00000112110.51052.594901351.16800-0.360303.681401.91470K562SRSF9
MRPL18ENSG00000112110.51504.321701190.601400.337303.240302.35220K562SYNCRIP
MRPL18ENSG00000112110.5790.126001062.74880-0.427603.506201.69790K562TBRG4
MRPL18ENSG00000112110.5744.980201329.62250-0.8357010.335008.43030K562TIAL1
MRPL18ENSG00000112110.5994.934401412.80460-0.505905.237503.83470K562TRIM56
MRPL18ENSG00000112110.51828.426902602.42010-0.509305.544804.25380K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for MRPL18 is not available on ENCORE database.





8 RBPs can affect the splicing of MRPL18 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEMRPL18ENSG00000112110.5chr6+160211455160211671160210917160211092160211971160212158-0.151000.001610.05300excludedK562PRPF8
SEMRPL18ENSG00000112110.5chr6+160211455160211671160210917160211092160211971160212158-0.149000.000000.00003excludedK562AQR
SEMRPL18ENSG00000112110.5chr6+160211455160211671160210917160211092160211971160212158-0.255000.000000.00000excludedK562SUPV3L1
SEMRPL18ENSG00000112110.5chr6+160211455160211671160210917160211092160211971160212158-0.157000.000350.02326excludedK562EFTUD2
SEMRPL18ENSG00000112110.5chr6+1602116991602118191602109171602110921602119711602121580.221000.000610.01712includedHepG2SRSF1
SEMRPL18ENSG00000112110.5chr6+160218318160218401160211944160212158160219083160219468-0.074000.000110.00681excludedK562TARDBP
SEMRPL18ENSG00000112110.5chr6+160211699160211819160210917160211092160211971160212158-0.251000.000690.02878excludedHepG2HNRNPC
A5SSMRPL18ENSG00000112110.5chr6+160218318160218550160218318160218401160219083160219468-0.072000.000000.00027shorterK562RBM22
MXEMRPL18ENSG00000112110.5chr6+160211971160212158160218241160218401160210843160210920160219083160219468-0.208000.002600.020762includedK562AQR
MXEMRPL18ENSG00000112110.5chr6+1602119711602121421602183181602185501602114971602116711602190831602194680.188000.000000.000001includedK562TARDBP
MXEMRPL18ENSG00000112110.5chr6+1602119711602121581602183181602185501602114971602116711602190831602194680.198000.000000.000001includedK562TARDBP
MXEMRPL18ENSG00000112110.5chr6+1602119711602121581602183181602185501602114971602116711602190831602194680.090000.004180.066131includedK562PRPF8
MXEMRPL18ENSG00000112110.5chr6+1602119711602121581602183181602184011602109171602110921602190831602194680.127000.002140.041171includedK562PRPF8
MXEMRPL18ENSG00000112110.5chr6+160211455160211671160211699160211819160210917160211092160211971160212158-0.056000.000570.015282includedK562PRPF8

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for MRPL18 is not avaliable on ENCORE database.