MEN1

General Information

Gene Name       : MEN1
Gene ID             : ENSG00000133895.14
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: MEN1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878MEN1ENSG00000133895.148.2015.2711.73ENCSR000AEF
HepG2MEN1ENSG00000133895.1433.6620.0226.84ENCSR985KAT
K562MEN1ENSG00000133895.1434.9028.7531.82ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for MEN1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • MEN1 RNA is bound by 14 proteins.  







eCLIP assay for MEN1 is not avaliable on ENCORE database.





14 proteins are bound to MEN1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr116457113664571211-3'-UTR,intron-Distal4.765276.07551HepG2LARP4
chr116457759064577665-3'-UTR,5'-UTR,intron-Distal,intron-Proximal5.079445.70555K562PRPF8
chr116457757364577632-3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal3.312115.81258K562AQR
chr116457756564577606-3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal4.795686.05264HepG2DDX3X
chr116457148764571535-3'-UTR,intron-Distal3.953683.02541K562IGF2BP2
chr116457112264571252-3'-UTR,intron-Distal3.891943.10464K562IGF2BP2
chr116457154464571595-3'-UTR,intron-Distal3.411355.50025HepG2IGF2BP1
chr116457142664571460-3'-UTR,intron-Distal5.154298.49217K562YBX3
chr116457146064571468-3'-UTR,intron-Distal4.873946.97425K562YBX3
chr116457758264577637-3'-UTR,5'-UTR,intron-Distal,intron-Proximal4.183716.23016HepG2PRPF8
chr116457153764571606-3'-UTR,intron-Distal3.439334.15940K562IGF2BP1
chr116457757364577623-3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal3.618724.57180HepG2AQR
chr116457159564571662-3'-UTR,intron-Distal4.614383.83024HepG2IGF2BP1
chr116457149364571552-3'-UTR,intron-Distal3.980563.02250K562YBX3
chr116457101164571073-3'-UTR,intron-Distal5.1598417.98612K562PUM2
chr116457168064571745-3'-UTR,intron-Distal,intron-Proximal3.519753.70321K562IGF2BP2
chr116457762364577691-5'-UTR,intron-Distal,intron-Proximal5.326249.24583HepG2AQR
chr116457787564577946-5'-UTR,intron-Distal5.7348210.44569K562AQR
chr116457796164578037-5'-UTR,intron-Distal,intron-Proximal4.060994.26442K562DDX3X
chr116457794664577995-5'-UTR,intron-Distal,intron-Proximal4.153074.98250K562AQR
chr116457792164577991-5'-UTR,intron-Distal,intron-Proximal3.572516.65114HepG2PRPF8
chr116457780464577841-5'-UTR,intron-Distal3.941833.15006K562RBM15
chr116457763764577686-5'-UTR,intron-Distal,intron-Proximal3.481514.51097HepG2PRPF8
chr116457789164577954-5'-UTR,intron-Distal3.407393.99908K562BUD13
chr116457791464577973-5'-UTR,intron-Distal,intron-Proximal3.766236.30673HepG2DDX3X
chr116457539564575493-CDS,intron-Distal,intron-Proximal3.376694.17944K562BUD13
chr116457497964575026-CDS,intron-Distal,intron-Proximal5.116075.26064K562AQR
chr116457501764575077-CDS,intron-Distal,intron-Proximal3.698993.32039HepG2PPIG
chr116457382764573930-CDS,intron-Distal,intron-Proximal4.624755.68078HepG2AQR
chr116457743864577479-CDS,intron-Distal4.032893.48187K562RBM15
chr116457498264575026-CDS,intron-Distal,intron-Proximal3.910295.93840HepG2PRPF8
chr116457363464573698-intron-Distal,intron-Proximal5.035845.26064K562AQR
chr116457353464573672-intron-Distal,intron-Proximal5.8511215.94630HepG2HNRNPK
chr116457353764573658-intron-Distal,intron-Proximal4.195666.57521HepG2DDX59
chr116457353064573603-intron-Distal,intron-Proximal4.079873.91009K562HNRNPK
chr116457385864573949-intron-Distal,intron-Proximal4.040483.25678HepG2SF3B4
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for MEN1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for MEN1 is not available on ENCORE database.

  • 80 RBPs can affect the levels of MEN1.  








The Knockdown/knockout RNA-Seq assay for MEN1 is not available on ENCORE database.





80 RBPs can affect the gene expression of MEN1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
MEN1ENSG00000133895.10829.341601018.90210-0.297002.855802.07780HepG2AKAP8L
MEN1ENSG00000133895.10410.47650625.96510-0.608804.538203.41180HepG2BCLAF1
MEN1ENSG00000133895.101236.103601602.49130-0.374503.223102.58330HepG2BOP1
MEN1ENSG00000133895.10831.622901142.38110-0.458003.924703.02930HepG2CALR
MEN1ENSG00000133895.10985.208201471.17190-0.578506.066605.08300HepG2CPSF6
MEN1ENSG00000133895.10570.271901049.34250-0.8798017.2489015.91730HepG2CELF1
MEN1ENSG00000133895.101195.34170937.915500.349804.824903.76390HepG2DDX19B
MEN1ENSG00000133895.10401.66780636.60480-0.664406.444205.05590HepG2DDX24
MEN1ENSG00000133895.10800.29980970.22630-0.277802.453101.80880HepG2DKC1
MEN1ENSG00000133895.10839.06670687.344100.287702.132001.54550HepG2DNAJC2
MEN1ENSG00000133895.10432.92630599.04560-0.468502.514201.46490HepG2AGO1
MEN1ENSG00000133895.10853.439101113.14070-0.383304.441303.42200HepG2EIF4G1
MEN1ENSG00000133895.10846.167801066.32080-0.333602.261001.51980HepG2EIF4G2
MEN1ENSG00000133895.101055.392601597.79510-0.5983012.5034011.37580HepG2ETF1
MEN1ENSG00000133895.101303.11890886.733900.555303.430802.66550HepG2FXR1
MEN1ENSG00000133895.101086.383701591.49970-0.550905.488504.63270HepG2HNRNPLL
MEN1ENSG00000133895.10934.29180773.499000.272402.070901.53710HepG2HNRNPU
MEN1ENSG00000133895.10965.69480790.096900.289402.422201.73110HepG2ILF2
MEN1ENSG00000133895.101330.07030891.905900.576403.759503.03400HepG2MATR3
MEN1ENSG00000133895.101004.41090650.832500.625902.511301.47490HepG2NONO
MEN1ENSG00000133895.101091.74420830.518500.394504.848804.08090HepG2PCBP1
MEN1ENSG00000133895.10943.16200689.892400.451005.105304.13250HepG2PPIL4
MEN1ENSG00000133895.10404.02770546.23410-0.435102.712301.91110HepG2PRPF8
MEN1ENSG00000133895.10827.540701068.02550-0.368002.966002.35240HepG2PUF60
MEN1ENSG00000133895.10863.355201032.92760-0.258702.484401.89270HepG2PUS1
MEN1ENSG00000133895.10274.77490616.15080-1.165006.549705.49040HepG2RAVER1
MEN1ENSG00000133895.10877.73420642.578000.449802.361201.38460HepG2RCC2
MEN1ENSG00000133895.101170.50350940.505100.315503.251302.67460HepG2NELFE
MEN1ENSG00000133895.101069.62920875.996800.288002.769202.15260HepG2RECQL
MEN1ENSG00000133895.10779.844501241.25430-0.670507.864506.80400HepG2RPLP0
MEN1ENSG00000133895.10880.96870693.857700.344402.425301.84550HepG2RPS19
MEN1ENSG00000133895.10392.19500540.30990-0.462202.820402.02710HepG2RRP9
MEN1ENSG00000133895.10369.76810670.95260-0.859603.788601.98760HepG2RTF1
MEN1ENSG00000133895.10990.58020688.811700.524104.143103.38240HepG2SAFB2
MEN1ENSG00000133895.101465.76140634.273101.208404.324602.54410HepG2SF1
MEN1ENSG00000133895.101043.20800879.819100.245602.145101.61440HepG2SF3B4
MEN1ENSG00000133895.101020.80600803.231400.345703.453602.74740HepG2SMN1
MEN1ENSG00000133895.101286.435501508.31060-0.229602.706602.20820HepG2SRFBP1
MEN1ENSG00000133895.101242.641401695.00300-0.447902.951401.91160HepG2SRSF3
MEN1ENSG00000133895.101241.968801054.511200.236002.143401.58400HepG2SRSF5
MEN1ENSG00000133895.10627.85600747.15490-0.251001.850901.38310HepG2SRSF9
MEN1ENSG00000133895.101019.796401309.52430-0.360804.830604.18950HepG2SSB
MEN1ENSG00000133895.101530.070601199.276900.351305.332504.51940HepG2SUCLG1
MEN1ENSG00000133895.10610.22900825.51910-0.436004.150303.48450HepG2TAF15
MEN1ENSG00000133895.101084.711601551.23700-0.516105.322004.36250HepG2TARDBP
MEN1ENSG00000133895.10990.66410751.449800.398603.173502.64370HepG2TIAL1
MEN1ENSG00000133895.101002.27040758.327200.402304.382003.70470HepG2TRIM56
MEN1ENSG00000133895.101458.25250659.481601.144703.959702.76790HepG2U2AF2
MEN1ENSG00000133895.101157.088801345.20050-0.217302.148901.52080HepG2UPF1
MEN1ENSG00000133895.101553.258301298.739900.258102.942002.32740HepG2UTP3
MEN1ENSG00000133895.10927.05520694.179600.417202.091801.45340HepG2XRN2
MEN1ENSG00000133895.101222.706601479.46460-0.275003.735403.12510HepG2ZNF622
MEN1ENSG00000133895.10827.878201167.08850-0.495406.297105.49390K562AGGF1
MEN1ENSG00000133895.10951.994601214.37730-0.351202.939102.26510K562AKAP8L
MEN1ENSG00000133895.101149.435401628.26830-0.502404.820603.65790K562BOP1
MEN1ENSG00000133895.101399.25060962.450000.539805.552003.92930K562CCAR1
MEN1ENSG00000133895.101351.574901731.35380-0.357303.358302.49190K562CPSF6
MEN1ENSG00000133895.101548.519702407.00630-0.6364011.118909.23760K562CELF1
MEN1ENSG00000133895.101427.311501077.530500.405503.297501.83420K562DHX30
MEN1ENSG00000133895.10562.36190405.163400.472904.088003.13100K562EIF3G
MEN1ENSG00000133895.10837.14440617.528500.438903.270602.38170K562EIF4A3
MEN1ENSG00000133895.10722.38850954.73380-0.402302.637401.54180K562FKBP4
MEN1ENSG00000133895.101150.94930642.201300.8416016.3722015.00900K562FXR1
MEN1ENSG00000133895.1084.13360283.38350-1.7520014.4897012.58340K562G3BP2
MEN1ENSG00000133895.101544.663301958.41320-0.342403.038902.24860K562GRSF1
MEN1ENSG00000133895.10243.37420499.86110-1.038406.139804.23860K562HNRNPK
MEN1ENSG00000133895.101551.165102139.44280-0.463902.452901.69990K562HSPD1
MEN1ENSG00000133895.10978.390101288.86700-0.397602.793401.96340K562KIF1C
MEN1ENSG00000133895.10784.17760526.110800.575705.707004.48720K562MAGOH
MEN1ENSG00000133895.10820.65010524.979100.644405.200403.88470K562MATR3
MEN1ENSG00000133895.101464.497602086.90290-0.511005.605004.00060K562MSI2
MEN1ENSG00000133895.101117.091501681.31620-0.5898012.5160010.94240K562MTPAP
MEN1ENSG00000133895.10690.204501012.01860-0.552103.607402.56750K562NAA15
MEN1ENSG00000133895.101565.939901868.18850-0.254604.058503.17360K562NSUN2
MEN1ENSG00000133895.10728.44500511.181300.510903.647602.89630K562PTBP1
MEN1ENSG00000133895.10728.980601204.55180-0.724508.819707.89840K562PUS1
MEN1ENSG00000133895.10148.82320270.35890-0.861303.304501.72730K562RAVER1
MEN1ENSG00000133895.10920.940601173.46970-0.349603.604502.94130K562RBM15
MEN1ENSG00000133895.10812.64590489.930500.729908.136206.59070K562RBM22
MEN1ENSG00000133895.101123.09680899.605200.320002.477601.54380K562RCC2
MEN1ENSG00000133895.10869.74210454.191600.9372010.057008.02780K562RPS3
MEN1ENSG00000133895.101575.746801070.260800.558005.476003.95120K562SAFB
MEN1ENSG00000133895.10535.67330850.31800-0.666602.530001.40050K562SF1
MEN1ENSG00000133895.10403.74310294.563600.454802.932602.05100K562SF3B4
MEN1ENSG00000133895.101114.99770852.803100.386703.058701.96750K562SRFBP1
MEN1ENSG00000133895.10809.78260501.175600.692107.910506.72350K562SRSF1
MEN1ENSG00000133895.10822.32360438.432100.9073010.917608.70650K562SRSF4
MEN1ENSG00000133895.101807.597701204.636400.585408.161806.74500K562SYNCRIP
MEN1ENSG00000133895.10817.21370507.120000.688305.270604.27710K562TARDBP
MEN1ENSG00000133895.10743.72000489.201400.604204.777603.65730K562TIA1
MEN1ENSG00000133895.101704.755602160.57260-0.341802.505701.30410K562TROVE2
MEN1ENSG00000133895.10156.39170283.61210-0.858806.316605.11180K562U2AF2
MEN1ENSG00000133895.101293.456001694.98220-0.390003.400202.43240K562WDR3
MEN1ENSG00000133895.101151.565101584.27340-0.460202.559401.73530K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for MEN1 is not available on ENCORE database.





28 RBPs can affect the splicing of MEN1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEMEN1ENSG00000133895.10chr11-645733596457348564573106645732426457370364573840-0.111000.000450.01997excludedK562PRPF8
SEMEN1ENSG00000133895.10chr11-645733596457348564573106645732426457370364573840-0.052000.001390.07630excludedHepG2RBM22
SEMEN1ENSG00000133895.10chr11-645733596457348564573106645732426457370364573840-0.175000.000000.00255excludedK562PCBP1
SEMEN1ENSG00000133895.10chr11-645733596457348564573106645732426457370364573840-0.125000.002690.08227excludedK562FXR1
SEMEN1ENSG00000133895.10chr11-6457335964573485645731066457324264573703645738400.087000.000200.04750includedK562HNRNPA1
SEMEN1ENSG00000133895.10chr11-6457335964573485645731066457324264573703645738400.228000.001430.02292includedK562PUS1
SEMEN1ENSG00000133895.10chr11-645733596457348564573106645732426457370364573840-0.056000.000310.01714excludedHepG2MATR3
SEMEN1ENSG00000133895.10chr11-6457370364573840645731066457324264574482645745700.062000.000960.08459includedHepG2LARP4
SEMEN1ENSG00000133895.10chr11-6457335964573485645731066457324264573703645738400.185000.000150.05164includedK562PPIL4
SEMEN1ENSG00000133895.10chr11-6457335964573485645731066457324264573703645738400.125000.000750.02017includedHepG2SRSF1
SEMEN1ENSG00000133895.10chr11-6457335964573485645731066457324264573703645738400.224000.000010.00222includedK562HNRNPUL1
SEMEN1ENSG00000133895.10chr11-645733596457348564573106645732426457370364573840-0.082000.000200.02518excludedHepG2SUPV3L1
SEMEN1ENSG00000133895.10chr11-6457335964573485645731066457324264573703645738400.069000.001550.05234includedK562HNRNPU
SEMEN1ENSG00000133895.10chr11-6457335964573480645731066457324264573703645738400.104000.000540.08229includedK562NPM1
A3SSMEN1ENSG00000133895.10chr11-6457502364575250645750236457515264575362645755710.207000.000040.00643longerHepG2HNRNPK
A3SSMEN1ENSG00000133895.10chr11-6457502364575250645750236457515264575362645755710.350000.000000.00000longerHepG2TAF15
A3SSMEN1ENSG00000133895.10chr11-6457502364575250645750236457515264575362645756020.270000.000000.00000longerK562AQR
A3SSMEN1ENSG00000133895.10chr11-6457502364575250645750236457515264575362645755710.454000.000000.00083longerK562HNRNPK
A3SSMEN1ENSG00000133895.10chr11-6457502364575250645750236457515264575362645755710.125000.000320.02841longerHepG2SF3B4
RIMEN1ENSG00000133895.10chr11-6457310664573840645731066457324264573703645738400.268000.000900.04508includedHepG2SFPQ
RIMEN1ENSG00000133895.10chr11-6457310664573840645731066457324264573703645738400.490000.000000.00007includedHepG2U2AF2
RIMEN1ENSG00000133895.10chr11-6457310664573840645731066457324264573703645738400.218000.004160.06790includedHepG2IGF2BP3
RIMEN1ENSG00000133895.10chr11-6457310664573840645731066457324264573703645738400.327000.000770.02242includedHepG2FTO
RIMEN1ENSG00000133895.10chr11-6457310664573840645731066457324264573703645738400.111000.008970.07885includedHepG2QKI
RIMEN1ENSG00000133895.10chr11-6457310664573840645731066457324264573703645738400.210000.000030.00059includedHepG2TAF15
RIMEN1ENSG00000133895.10chr11-6457310664573840645731066457324264573703645738400.248000.000000.00011includedHepG2U2AF1
RIMEN1ENSG00000133895.10chr11-6457310664573840645731066457324264573703645738400.111000.001740.03079includedHepG2G3BP1
RIMEN1ENSG00000133895.10chr11-6457310664573840645731066457324264573703645738400.154000.000000.00013includedHepG2NCBP2
RIMEN1ENSG00000133895.10chr11-6457310664573840645731066457324264573703645738400.161000.000380.00417includedHepG2SF3B4
RIMEN1ENSG00000133895.10chr11-6457455164574750645745516457457064574650645747500.084000.005720.07235includedHepG2SRSF9
RIMEN1ENSG00000133895.10chr11-6457310664573840645731066457324264573703645738400.415000.000000.00000includedHepG2HNRNPK
RIMEN1ENSG00000133895.10chr11-6457310664573840645731066457324264573703645738400.202000.000580.00804includedK562EFTUD2
RIMEN1ENSG00000133895.10chr11-6457310664573840645731066457324264573703645738400.336000.000000.00000includedK562AQR
RIMEN1ENSG00000133895.10chr11-6457455164574750645745516457457064574650645747500.067000.002140.01340includedK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for MEN1 is not avaliable on ENCORE database.