MEF2C

General Information

Gene Name       : MEF2C
Gene ID             : ENSG00000081189.15
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: MEF2C)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878MEF2CENSG00000081189.15164.02142.05153.04ENCSR000AEF
HepG2MEF2CENSG00000081189.150.020.010.01ENCSR985KAT
K562MEF2CENSG00000081189.1545.0445.6245.33ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for MEF2C is not avaliable on ENCORE database.



Proteins bound to RNA
  • MEF2C RNA is bound by 8 proteins.  







eCLIP assay for MEF2C is not avaliable on ENCORE database.





8 proteins are bound to MEF2C RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr58811963588119730-3'-UTR,5'-UTR,intron-Distal,intron-Proximal3.220583.17151K562UCHL5
chr58801740888017442-3'-UTR,intron-Distal4.719995.45041K562PUM2
chr58801714388017196-3'-UTR,intron-Distal3.874056.89197K562PUM2
chr58801803388018114-3'-UTR,intron-Distal4.147796.89197K562PUM2
chr58802504688025077-CDS,intron-Distal4.880556.51828K562YBX3
chr58811954488119594-CDS,intron-Distal,intron-Proximal3.028924.30396K562UCHL5
chr58802432388024429-CDS,intron-Distal5.7124912.96622K562YBX3
chr58802507788025129-CDS,intron-Distal4.844096.97425K562YBX3
chr58802755288027638-CDS,intron-Distal,intron-Proximal4.292393.87582K562ZNF622
chr58810045888100620-CDS,intron-Distal,intron-Proximal3.096396.57854K562UCHL5
chr58810047488100618-CDS,intron-Distal,intron-Proximal4.510437.27704K562ZNF622
chr58816776288167870-intron-Distal3.410303.68839K562KHSRP
chr58816878188168885-intron-Distal4.085777.08696K562TARDBP
chr58807240188072495-intron-Distal4.761573.42734K562PTBP1
chr58807533588075399-intron-Distal4.166274.27660K562HNRNPL
chr58814645888146525-intron-Distal4.271364.92524K562TARDBP
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for MEF2C is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for MEF2C is not available on ENCORE database.

  • 103 RBPs can affect the levels of MEF2C.  








The Knockdown/knockout RNA-Seq assay for MEF2C is not available on ENCORE database.





103 RBPs can affect the gene expression of MEF2C :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
MEF2CENSG00000081189.91973.848201344.366500.554007.237705.27550K562AARS
MEF2CENSG00000081189.9473.69530976.16180-1.043204.356402.16790K562ADAR
MEF2CENSG00000081189.9852.329601725.80000-1.0178031.1852029.36730K562AGGF1
MEF2CENSG00000081189.91149.108701896.29780-0.7227011.146908.82070K562AKAP8
MEF2CENSG00000081189.91011.107001795.74960-0.8287013.8698012.23510K562AKAP8L
MEF2CENSG00000081189.9359.333802291.00230-2.6726098.9460095.98760K562AQR
MEF2CENSG00000081189.9861.772001206.56240-0.485506.150604.06860K562BCCIP
MEF2CENSG00000081189.9921.945801165.88950-0.338703.712902.59270K562BCLAF1
MEF2CENSG00000081189.91061.417001913.93510-0.850605.248904.03570K562BOP1
MEF2CENSG00000081189.9744.958501072.09480-0.525206.049803.81520K562CEBPZ
MEF2CENSG00000081189.91918.169102714.81210-0.501104.491602.57870K562CKAP4
MEF2CENSG00000081189.91185.332402845.92680-1.2636013.5546011.24780K562CNOT7
MEF2CENSG00000081189.91206.650402035.18260-0.754205.146904.08360K562CPSF6
MEF2CENSG00000081189.9642.863701021.77320-0.668503.458001.30650K562CPSF7
MEF2CENSG00000081189.9676.82730884.50070-0.386102.652501.61940K562CSTF2
MEF2CENSG00000081189.91799.310703700.11880-1.0401018.8654016.55170K562CELF1
MEF2CENSG00000081189.9725.782501232.20650-0.7636014.2408011.53460K562DDX21
MEF2CENSG00000081189.9690.47350941.07860-0.446702.771201.46370K562DDX6
MEF2CENSG00000081189.9659.129901069.94250-0.698903.615702.06580K562DHX30
MEF2CENSG00000081189.9708.984701089.54200-0.619903.250301.33830K562DNAJC2
MEF2CENSG00000081189.9779.132001035.56290-0.410502.233601.41360K562EFTUD2
MEF2CENSG00000081189.92507.084001658.501100.5960013.0723011.68760K562EIF2S2
MEF2CENSG00000081189.9670.03160969.72360-0.533304.722603.65080K562EIF4A3
MEF2CENSG00000081189.92023.890903009.79950-0.572509.324307.63550K562EIF4G2
MEF2CENSG00000081189.91408.778402189.80100-0.636403.657801.74020K562ESF1
MEF2CENSG00000081189.91014.299001383.96260-0.448304.937703.19730K562EXOSC5
MEF2CENSG00000081189.9893.065402059.68300-1.2056013.6627011.62050K562FIP1L1
MEF2CENSG00000081189.91743.878601276.698800.449803.832702.47580K562FKBP4
MEF2CENSG00000081189.91267.802002070.51690-0.707704.794903.66680K562FMR1
MEF2CENSG00000081189.9881.421701754.84860-0.993407.524405.93880K562FTO
MEF2CENSG00000081189.9738.56410407.295600.858504.548001.79450K562FXR2
MEF2CENSG00000081189.91089.919601584.76610-0.540006.708304.35160K562G3BP1
MEF2CENSG00000081189.91073.950702006.91360-0.9021023.3848020.70820K562GLRX3
MEF2CENSG00000081189.9803.651201943.19490-1.2738010.168808.63060K562GPKOW
MEF2CENSG00000081189.9808.359902210.13100-1.4511043.2264040.13890K562GRSF1
MEF2CENSG00000081189.9650.128501647.01780-1.3411035.8157032.91990K562HNRNPA1
MEF2CENSG00000081189.9940.337701755.18930-0.900405.175703.33340K562HNRNPA2B1
MEF2CENSG00000081189.91630.022902663.27960-0.708305.381203.18960K562HNRNPAB
MEF2CENSG00000081189.9738.967801471.60000-0.9938010.471509.36980K562HNRNPC
MEF2CENSG00000081189.9829.589301313.87940-0.663405.964804.20590K562HNRNPF
MEF2CENSG00000081189.92288.698301655.446500.467204.350502.76540K562HNRNPK
MEF2CENSG00000081189.91130.405101693.99360-0.583604.815803.55080K562HNRNPM
MEF2CENSG00000081189.9821.057401823.97790-1.1515034.5282031.76690K562HNRNPU
MEF2CENSG00000081189.91576.681202792.66820-0.824807.967906.63370K562HSPD1
MEF2CENSG00000081189.9876.518301232.69620-0.492003.705601.53560K562IGF2BP1
MEF2CENSG00000081189.91527.130902597.57440-0.766305.080203.11180K562ILF2
MEF2CENSG00000081189.9642.27760998.52430-0.636605.962903.78200K562ILF3
MEF2CENSG00000081189.9688.69160965.19900-0.487003.957502.17860K562KHDRBS1
MEF2CENSG00000081189.91289.782801905.82160-0.563307.168505.68970K562KIF1C
MEF2CENSG00000081189.9805.323301658.99360-1.042707.663206.02150K562KRR1
MEF2CENSG00000081189.91909.147501424.277000.422604.454102.63340K562LARP7
MEF2CENSG00000081189.91367.292801742.05990-0.349503.193302.28720K562MAGOH
MEF2CENSG00000081189.91359.913001824.27340-0.423804.340902.90480K562MAK16
MEF2CENSG00000081189.9979.873701738.48030-0.8272015.5107013.23620K562MATR3
MEF2CENSG00000081189.9806.083401896.73440-1.234509.248907.57890K562METAP2
MEF2CENSG00000081189.9863.467102110.00920-1.2890055.8312053.13330K562MTPAP
MEF2CENSG00000081189.9966.801802344.40220-1.2779076.4604073.51480K562NSUN2
MEF2CENSG00000081189.91200.176102734.10180-1.1878012.331509.78240K562PABPC1
MEF2CENSG00000081189.9749.485501535.60040-1.034806.532004.81140K562PABPN1
MEF2CENSG00000081189.91390.417601702.99960-0.292602.630601.31650K562PCBP1
MEF2CENSG00000081189.9614.222301760.39380-1.5191031.7598029.20020K562PCBP3
MEF2CENSG00000081189.91825.725303092.62380-0.760407.785505.59930K562PNPT1
MEF2CENSG00000081189.9583.003401350.27170-1.2117027.8862025.58060K562POLR2G
MEF2CENSG00000081189.91469.110202337.96730-0.670306.437105.09580K562PPIG
MEF2CENSG00000081189.9676.042001007.71610-0.575904.038303.13170K562PRPF8
MEF2CENSG00000081189.91361.850501692.54260-0.313602.910302.23180K562PTBP1
MEF2CENSG00000081189.92412.590103284.00430-0.444902.498501.72380K562PUF60
MEF2CENSG00000081189.92663.609703492.44530-0.390905.011403.54150K562PUM1
MEF2CENSG00000081189.92557.611303422.52610-0.420305.378804.02060K562PUM2
MEF2CENSG00000081189.9556.047201781.05930-1.6795042.4748040.28500K562PUS1
MEF2CENSG00000081189.9946.617801735.23440-0.8743020.0375018.40180K562RBM15
MEF2CENSG00000081189.91278.539101622.78290-0.344002.848101.99340K562RBM22
MEF2CENSG00000081189.9824.693101203.40480-0.545204.548303.27490K562RCC2
MEF2CENSG00000081189.91158.31980569.459301.0243013.6133011.27740K562RPS3
MEF2CENSG00000081189.91347.963902235.41160-0.729803.845301.68250K562SAFB2
MEF2CENSG00000081189.91455.764302592.28890-0.832406.671904.21440K562SBDS
MEF2CENSG00000081189.91390.773002313.33790-0.7341018.9507016.97190K562SF3A3
MEF2CENSG00000081189.9910.386201847.69640-1.021207.054305.45670K562SF3B1
MEF2CENSG00000081189.9343.003701712.52700-2.3198024.6295020.54660K562SFPQ
MEF2CENSG00000081189.9518.192701052.88900-1.022809.220607.01820K562SLBP
MEF2CENSG00000081189.91944.417002370.06560-0.285604.688903.51000K562SRPK2
MEF2CENSG00000081189.9900.882401659.28960-0.8812016.9108015.17280K562SRSF1
MEF2CENSG00000081189.91201.224201567.15720-0.383603.309602.14250K562SRSF5
MEF2CENSG00000081189.9671.705901099.56320-0.7110012.130709.64150K562SRSF7
MEF2CENSG00000081189.9693.874801170.55190-0.754403.485902.01830K562SSB
MEF2CENSG00000081189.92012.892502702.61900-0.425103.096701.64810K562SSRP1
MEF2CENSG00000081189.91415.250402472.01270-0.804605.640403.77530K562STAU1
MEF2CENSG00000081189.91518.744902537.04740-0.740303.863601.92530K562STIP1
MEF2CENSG00000081189.9937.071901929.26910-1.041806.062203.72490K562SUPT6H
MEF2CENSG00000081189.9574.06770975.98370-0.765605.056503.64800K562SUPV3L1
MEF2CENSG00000081189.91695.376101354.372100.323902.501101.72250K562SYNCRIP
MEF2CENSG00000081189.91193.564801679.23700-0.492504.823303.87700K562TARDBP
MEF2CENSG00000081189.91341.366601001.907900.420902.954501.30820K562TBRG4
MEF2CENSG00000081189.9685.051901269.05660-0.889508.666306.94050K562TIAL1
MEF2CENSG00000081189.9502.991701347.81770-1.4220015.2571012.64730K562TRIM56
MEF2CENSG00000081189.91772.119902410.09610-0.443603.079401.60120K562TRIP6
MEF2CENSG00000081189.91335.272001032.810100.370502.935001.88000K562UCHL5
MEF2CENSG00000081189.91519.537502485.82000-0.7101021.5099019.74070K562UPF1
MEF2CENSG00000081189.91047.250801805.63820-0.785904.802202.93590K562UTP18
MEF2CENSG00000081189.91797.191502698.32420-0.586306.024804.27280K562UTP3
MEF2CENSG00000081189.91179.703802127.03670-0.8504017.1783015.00150K562WDR3
MEF2CENSG00000081189.92041.850102714.62770-0.410904.820703.11280K562WRN
MEF2CENSG00000081189.91137.437602580.78580-1.1820029.3132026.43890K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for MEF2C is not available on ENCORE database.





10 RBPs can affect the splicing of MEF2C :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEMEF2CENSG00000081189.9chr5-8815862388158779881195518811974788178771881789640.071000.000530.09316includedK562WDR3
SEMEF2CENSG00000081189.9chr5-880448868804493488027545880277188804767388047860-0.099000.009840.08022excludedK562AQR
SEMEF2CENSG00000081189.9chr5-8815862388158779881195518811974788178771881790500.097000.003260.04477includedK562PUS1
SEMEF2CENSG00000081189.9chr5-881787718817881688119551881197478818030588180385-0.274000.000120.03201excludedK562APOBEC3C
SEMEF2CENSG00000081189.9chr5-881787718817881688119551881197478818030588180385-0.274000.000100.06407excludedK562PUM2
A3SSMEF2CENSG00000081189.9chr5-8802766888027755880276688802771888044886880449980.054000.011870.06118longerK562AQR
MXEMEF2CENSG00000081189.9chr5-8805680488056942880570018805714588047673880478608810041488100618-0.075000.004030.093032includedK562PTBP1
MXEMEF2CENSG00000081189.9chr5-8805680488056942880570018805714588047673880478608810041488100618-0.189000.000000.000002includedK562SRSF1
MXEMEF2CENSG00000081189.9chr5-8805680488056942880570018805714588047673880478608810041488100618-0.115000.000250.011362includedK562EFTUD2
MXEMEF2CENSG00000081189.9chr5-8805680488056942880570018805714588047673880478608810041488100618-0.156000.000020.007552includedK562EIF3G
MXEMEF2CENSG00000081189.9chr5-8805680488056942880570018805718588047673880478608810041488100618-0.266000.000050.011602includedK562EIF3G
MXEMEF2CENSG00000081189.9chr5-8805680488056942880570018805714588047673880478608810041488100618-0.119000.000480.013432includedK562PRPF8

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for MEF2C is not avaliable on ENCORE database.