LMAN2L

General Information

Gene Name       : LMAN2L
Gene ID             : ENSG00000114988.11
Essential Gene : No

Functions

Localization

Domains (AlphaFold: LMAN2L)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878LMAN2LENSG00000114988.114.976.165.56ENCSR000AEF
HepG2LMAN2LENSG00000114988.1138.4345.9342.18ENCSR985KAT
K562LMAN2LENSG00000114988.117.388.387.88ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for LMAN2L is not avaliable on ENCORE database.



Proteins bound to RNA
  • LMAN2L RNA is bound by 15 proteins.  







eCLIP assay for LMAN2L is not avaliable on ENCORE database.





15 proteins are bound to LMAN2L RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr29737180197371895-3'-UTR,intron-Distal3.593855.72266HepG2AKAP1
chr29737288197372974-3'-UTR,intron-Distal,intron-Proximal5.015858.34384HepG2AKAP1
chr29737240897372491-3'-UTR,intron-Distal3.276634.48159HepG2LARP4
chr29737226597372332-3'-UTR,intron-Distal3.834915.85347HepG2UPF1
chr29737764997377711-3'-UTR,CDS,intron-Distal,intron-Proximal5.296217.93299HepG2SND1
chr29737173397371810-3'-UTR,intron-Distal4.744626.20043HepG2UPF1
chr29737270997372802-3'-UTR,intron-Distal,intron-Proximal4.135956.42285HepG2AKAP1
chr29737313397373193-3'-UTR,CDS,intron-Distal3.835783.05889HepG2SF3B4
chr29737266897372856-3'-UTR,intron-Distal,intron-Proximal5.1686214.58493HepG2UPF1
chr29737235997372473-3'-UTR,intron-Distal4.7031910.52454HepG2AKAP1
chr29737740297377472-3'-UTR,CDS,intron-Distal,intron-Proximal4.785288.26344HepG2RPS3
chr29737734297377401-3'-UTR,CDS,intron-Distal,intron-Proximal4.119063.86479HepG2PRPF8
chr29737739297377488-3'-UTR,CDS,intron-Distal,intron-Proximal4.653668.33615HepG2SND1
chr29737189597371946-3'-UTR,intron-Distal4.591324.13758HepG2AKAP1
chr29737181097371941-3'-UTR,intron-Distal5.4034110.35090HepG2UPF1
chr29737226897372340-3'-UTR,intron-Distal4.814104.92727HepG2AKAP1
chr29737262697372676-3'-UTR,intron-Distal4.259844.13758HepG2AKAP1
chr29737291697372965-3'-UTR,intron-Distal,intron-Proximal4.302724.68979HepG2UPF1
chr29737237197372493-3'-UTR,intron-Distal5.8841816.41729HepG2UPF1
chr29737349597373536-3'-UTR,CDS,intron-Distal3.080724.24433HepG2SND1
chr29737756397377620-3'-UTR,CDS,intron-Distal,intron-Proximal3.327993.67792HepG2PRPF8
chr29740021597400261-5'-UTR,CDS,intron-Distal3.313733.32039HepG2PPIG
chr29740568197405791-5'-UTR,CDS,intron-Distal,intron-Proximal4.0834610.60272HepG2NCBP2
chr29739931497399338-5'-UTR,CDS,intron-Distal4.056483.19000HepG2SND1
chr29740293197402974-5'-UTR,CDS,intron-Distal,intron-Proximal4.454635.58061HepG2SUGP2
chr29740564197405688-5'-UTR,CDS,intron-Distal3.406853.73238HepG2LIN28B
chr29740561897405682-5'-UTR,CDS,intron-Distal4.5466418.55654K562TIA1
chr29740014497400195-5'-UTR,CDS,intron-Distal,intron-Proximal3.981635.79199HepG2SND1
chr29739926997399311-5'-UTR,CDS,intron-Distal4.376184.65414HepG2SND1
chr29740547297405552-intron-Distal3.866603.29554HepG2GTF2F1
chr29740204997402103-intron-Distal3.622907.27760HepG2SUGP2
chr29740221997402300-intron-Distal3.413408.75882HepG2SUGP2
chr29737684297376945-intron-Distal3.748847.06840HepG2QKI
chr29740062197400709-intron-Distal3.952465.28137HepG2MATR3
chr29737675297376825-intron-Distal4.566965.04993HepG2QKI
chr29740170797401756-intron-Distal3.990777.80398HepG2SUGP2
chr29740078497400917-intron-Distal5.6338113.16112HepG2SUGP2
chr29737697597377062-intron-Distal4.906005.85495HepG2QKI
chr29740079797400862-intron-Distal4.563245.70028HepG2MATR3
chr29740237997402439-intron-Distal3.894456.51675HepG2SUGP2
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for LMAN2L is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for LMAN2L is not available on ENCORE database.

  • 80 RBPs can affect the levels of LMAN2L.  








The Knockdown/knockout RNA-Seq assay for LMAN2L is not available on ENCORE database.





80 RBPs can affect the gene expression of LMAN2L :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
LMAN2LENSG00000114988.7392.09420971.16660-1.3085037.6686036.05340HepG2ACO1
LMAN2LENSG00000114988.71293.514501030.673400.327602.261101.35950HepG2ADAR
LMAN2LENSG00000114988.71583.901701359.412800.220402.201501.57650HepG2AUH
LMAN2LENSG00000114988.7798.55150523.182200.610005.553504.74110HepG2BOP1
LMAN2LENSG00000114988.7605.98600813.20000-0.424303.322502.48710HepG2CALR
LMAN2LENSG00000114988.71489.288801123.768800.406202.386301.48800HepG2CCAR1
LMAN2LENSG00000114988.7598.66140970.92160-0.6976013.5454012.30420HepG2CKAP4
LMAN2LENSG00000114988.7669.67040898.17440-0.423505.590904.45730HepG2DDX19B
LMAN2LENSG00000114988.71326.31940984.380700.430003.750202.67550HepG2DDX24
LMAN2LENSG00000114988.7750.078701074.01280-0.517903.116301.75310HepG2DDX27
LMAN2LENSG00000114988.7748.227801147.78210-0.617304.675003.69740HepG2DDX55
LMAN2LENSG00000114988.7810.166901028.66510-0.344504.314303.53300HepG2DNAJC2
LMAN2LENSG00000114988.7750.060801343.82130-0.8413010.229309.13200HepG2EIF2S1
LMAN2LENSG00000114988.7999.565701445.98040-0.532703.434502.67080HepG2EIF4B
LMAN2LENSG00000114988.71138.769801529.67160-0.425705.787804.65450HepG2EIF4G1
LMAN2LENSG00000114988.7711.24870955.39070-0.425702.578501.34870HepG2FKBP4
LMAN2LENSG00000114988.7271.40970818.10970-1.5918031.1683028.70430HepG2FUBP3
LMAN2LENSG00000114988.71301.19690975.125900.416102.613001.62520HepG2GNB2L1
LMAN2LENSG00000114988.7798.72580544.390400.553003.814303.07310HepG2GPKOW
LMAN2LENSG00000114988.7788.429701047.78750-0.410303.397602.69060HepG2HNRNPA1
LMAN2LENSG00000114988.7825.487701165.46480-0.497604.684903.79840HepG2HNRNPC
LMAN2LENSG00000114988.7879.186301064.18330-0.275502.738402.02450HepG2HNRNPF
LMAN2LENSG00000114988.71123.912201412.19920-0.329404.374803.54120HepG2HNRNPL
LMAN2LENSG00000114988.7543.502001157.75980-1.0910029.6262027.82510HepG2HNRNPU
LMAN2LENSG00000114988.7844.100801047.91150-0.312002.600001.89810HepG2IGF2BP1
LMAN2LENSG00000114988.7682.618001182.61420-0.7928020.7969019.00780HepG2ILF2
LMAN2LENSG00000114988.7927.111201421.14910-0.616204.628503.30150HepG2KHSRP
LMAN2LENSG00000114988.72155.127801507.372800.515604.388803.61070HepG2MATR3
LMAN2LENSG00000114988.71164.602201542.86020-0.405802.901802.25450HepG2NCBP2
LMAN2LENSG00000114988.71148.064701537.33650-0.421204.913903.90140HepG2NOL12
LMAN2LENSG00000114988.7655.808101053.82470-0.684303.436802.20850HepG2NONO
LMAN2LENSG00000114988.71044.702401374.64200-0.396005.413404.61090HepG2PCBP1
LMAN2LENSG00000114988.7382.88210534.87140-0.482303.759202.32180HepG2PKM
LMAN2LENSG00000114988.7826.403501032.63010-0.321402.997702.23390HepG2PPIL4
LMAN2LENSG00000114988.7796.345401118.58510-0.490202.616901.42760HepG2PRPF6
LMAN2LENSG00000114988.7836.499001398.76780-0.7417016.0003014.89330HepG2PTBP1
LMAN2LENSG00000114988.72576.927301467.571500.8121012.5916011.44330HepG2PUF60
LMAN2LENSG00000114988.7753.74750989.19120-0.392204.867104.09150HepG2PUS1
LMAN2LENSG00000114988.7670.704601514.86140-1.1754030.4222028.70100HepG2QKI
LMAN2LENSG00000114988.7571.759101026.78900-0.844705.300304.34190HepG2RAVER1
LMAN2LENSG00000114988.7756.08900933.43990-0.304002.607801.77300HepG2RBM15
LMAN2LENSG00000114988.7977.767101374.84870-0.491705.482504.56280HepG2RBM25
LMAN2LENSG00000114988.7634.57960935.71420-0.560304.771703.37070HepG2RCC2
LMAN2LENSG00000114988.71001.820401556.67920-0.6358012.4456011.45260HepG2NELFE
LMAN2LENSG00000114988.7920.587601449.86240-0.6553012.9951011.80580HepG2RECQL
LMAN2LENSG00000114988.7434.29960629.39960-0.535304.495603.73220HepG2RPS19
LMAN2LENSG00000114988.7815.394001062.64830-0.382103.087902.24120HepG2RPS2
LMAN2LENSG00000114988.7520.31730755.77720-0.538603.159702.30580HepG2RPS3A
LMAN2LENSG00000114988.7377.91100876.02750-1.2129014.6521013.09700HepG2RRP9
LMAN2LENSG00000114988.7514.303301031.03930-1.0034024.9249023.25890HepG2SAFB2
LMAN2LENSG00000114988.71703.51240940.618100.856708.758807.50370HepG2SF3A3
LMAN2LENSG00000114988.7351.93840514.19700-0.547003.678102.87470HepG2SF3B1
LMAN2LENSG00000114988.71046.269401456.26530-0.477007.324706.43650HepG2SF3B4
LMAN2LENSG00000114988.71110.614501407.29050-0.341604.562803.69700HepG2SLBP
LMAN2LENSG00000114988.71002.252901202.37110-0.262602.953502.29170HepG2SMN1
LMAN2LENSG00000114988.7659.62870999.56810-0.599704.174602.18200HepG2SND1
LMAN2LENSG00000114988.7955.957601473.41610-0.6241012.8049011.93680HepG2SRFBP1
LMAN2LENSG00000114988.7864.999201520.03890-0.8133020.2172019.18640HepG2SRSF1
LMAN2LENSG00000114988.7313.37310553.36850-0.820403.340302.23030HepG2SRSF3
LMAN2LENSG00000114988.7842.080201045.54320-0.312203.435602.67200HepG2SRSF7
LMAN2LENSG00000114988.71609.095601279.278300.330804.552103.92730HepG2SSB
LMAN2LENSG00000114988.7465.83230657.45110-0.497102.881601.75560HepG2STIP1
LMAN2LENSG00000114988.71298.247401647.94640-0.344104.036603.31080HepG2SUCLG1
LMAN2LENSG00000114988.7912.367001366.30710-0.582609.383208.44880HepG2TAF15
LMAN2LENSG00000114988.71130.58010707.528700.676102.916501.81940HepG2TBRG4
LMAN2LENSG00000114988.7975.542501255.41100-0.363903.388502.46760HepG2TIA1
LMAN2LENSG00000114988.7464.318401124.99890-1.2767029.6407028.32320HepG2TIAL1
LMAN2LENSG00000114988.7518.37790803.43750-0.632205.986805.07830HepG2U2AF1
LMAN2LENSG00000114988.7736.703001517.76870-1.0428013.3384011.45400HepG2UBE2L3
LMAN2LENSG00000114988.7501.54740675.02390-0.428602.556301.82740HepG2UCHL5
LMAN2LENSG00000114988.7961.40930805.371400.255402.282001.72660HepG2UTP3
LMAN2LENSG00000114988.7773.11000654.792300.239501.881901.31330HepG2ZC3H8
LMAN2LENSG00000114988.71281.38510917.442700.481908.940208.10070HepG2ZNF622
LMAN2LENSG00000114988.7752.681001025.97020-0.446902.550601.31070HepG2ZRANB2
LMAN2LENSG00000114988.7205.34030311.70290-0.602203.876703.22520K562AGGF1
LMAN2LENSG00000114988.7320.61850189.804600.756205.130404.01140K562EIF4A3
LMAN2LENSG00000114988.7212.82400145.409700.549402.232801.51870K562GPKOW
LMAN2LENSG00000114988.7648.69830508.717000.350602.154001.48190K562GRSF1
LMAN2LENSG00000114988.7400.24040217.050300.882707.080406.16790K562HNRNPC
LMAN2LENSG00000114988.7527.35630360.936300.546903.734102.81460K562HSPD1
LMAN2LENSG00000114988.7172.78760265.86210-0.621703.624802.55600K562MATR3
LMAN2LENSG00000114988.7879.98910559.923300.652206.268105.04340K562PUF60
LMAN2LENSG00000114988.7156.62290321.70670-1.038507.554006.70280K562PUS1
LMAN2LENSG00000114988.7163.01970248.18980-0.606403.137102.23650K562RBM22
LMAN2LENSG00000114988.7347.84140240.029700.535102.630901.83730K562RPS19
LMAN2LENSG00000114988.7362.39370259.765400.480203.089202.22780K562SF3A3
LMAN2LENSG00000114988.7167.53990253.73080-0.598802.958602.23010K562SRSF1
LMAN2LENSG00000114988.7522.23540279.129500.9037011.7549010.40220K562UPF1
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for LMAN2L is not available on ENCORE database.





7 RBPs can affect the splicing of LMAN2L :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SELMAN2LENSG00000114988.7chr2-9740287397402954974001459740026397403685974038040.326000.006660.09504includedK562SRSF1
SELMAN2LENSG00000114988.7chr2-9737884397378876973776009737776297399255973993380.114000.000130.00242includedHepG2U2AF2
SELMAN2LENSG00000114988.7chr2-973992559739933897377600973777629740014597400263-0.111000.000740.09798excludedHepG2TIA1
SELMAN2LENSG00000114988.7chr2-9739925597399338973776009737776297400145974002630.052000.001630.06024includedHepG2MATR3
SELMAN2LENSG00000114988.7chr2-9740287397402954974001459740026397403685974038040.429000.000240.08882includedK562NCBP2
SELMAN2LENSG00000114988.7chr2-9740287397402954974001459740026397403685974038040.431000.001770.03072includedK562HNRNPC
A3SSLMAN2LENSG00000114988.7chr2-9737345097373604973734509737357097377392973775070.213000.011810.06092longerK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for LMAN2L is not avaliable on ENCORE database.