KDM2A

General Information

Gene Name       : KDM2A
Gene ID             : ENSG00000173120.14
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: KDM2A)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878KDM2AENSG00000173120.1433.8844.6839.28ENCSR000AEF
HepG2KDM2AENSG00000173120.1423.8420.6522.24ENCSR985KAT
K562KDM2AENSG00000173120.1425.3425.3325.34ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for KDM2A is not avaliable on ENCORE database.



Proteins bound to RNA
  • KDM2A RNA is bound by 36 proteins.  







eCLIP assay for KDM2A is not avaliable on ENCORE database.





36 proteins are bound to KDM2A RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr116702283467022901+3'-UTR4.183843.61011HepG2AKAP1
chr116702275067022825+3'-UTR4.686505.64948HepG2UPF1
chr116702400567024079+3'-UTR4.1005612.30329HepG2PCBP2
chr116702458467024653+3'-UTR4.3860614.94065K562UPF1
chr116702369167023795+3'-UTR4.858678.52836K562AKAP1
chr116702331367023417+3'-UTR4.5160429.21733K562UPF1
chr116702309267023164+3'-UTR3.1402014.08659K562UPF1
chr116702031867020372+3'-UTR,CDS,intron-Proximal3.547135.43815HepG2PRPF8
chr116702386567023914+3'-UTR4.9833912.96016K562UPF1
chr116702483167024936+3'-UTR6.4440237.57444K562UPF1
chr116702369467023748+3'-UTR5.2415317.24848K562UPF1
chr116702429967024371+3'-UTR3.265373.90824K562YBX3
chr116702507567025134+3'-UTR,polyA_site5.0937917.53659K562PABPC4
chr116702339367023496+3'-UTR4.723375.35992HepG2UPF1
chr116702284267022888+3'-UTR4.218614.42909K562AKAP1
chr116702285867022912+3'-UTR3.837859.13151K562UPF1
chr116702402067024119+3'-UTR4.304324.80949K562HNRNPK
chr116702259067022701+3'-UTR4.249269.06961HepG2UPF1
chr116702402167024092+3'-UTR5.2976317.60288K562UPF1
chr116702294267023022+3'-UTR3.270865.45714HepG2UPF1
chr116702307067023154+3'-UTR4.4898912.68743HepG2PCBP2
chr116702404467024089+3'-UTR4.530965.53799K562FAM120A
chr116702470367024787+3'-UTR3.678164.98444HepG2GRSF1
chr116702308367023158+3'-UTR4.680598.80787K562AKAP1
chr116702032567020379+3'-UTR,CDS,intron-Proximal5.234827.63570K562AQR
chr116702485067024926+3'-UTR4.774373.92796K562AKAP1
chr116702341767023481+3'-UTR5.1004621.09426K562UPF1
chr116702277967022827+3'-UTR3.844803.19379HepG2AKAP1
chr116702337867023444+3'-UTR3.124496.31194K562FAM120A
chr116702261267022701+3'-UTR3.371928.80601K562RBM15
chr116702471267024777+3'-UTR3.180708.78952K562UPF1
chr116702017767020224+3'-UTR,CDS3.442173.90826K562ZNF622
chr116702320467023254+3'-UTR4.078939.04309K562UPF1
chr116702246367022536+3'-UTR,CDS3.077804.96088HepG2GRWD1
chr116702375667023813+3'-UTR5.3700416.18694K562UPF1
chr116702235467022432+3'-UTR,CDS3.291043.00343HepG2GRWD1
chr116688674866886828+5'-UTR3.509334.02244HepG2NCBP2
chr116688736966887422+5'-UTR3.263164.98411K562RBM15
chr116701046167010515+5'-UTR,CDS,intron-Distal,intron-Proximal4.603314.65563K562AQR
chr116688870366888717+5'-UTR,intron-Proximal3.398433.90826K562ZNF622
chr116688748166887526+5'-UTR,intron-Proximal3.660684.96634HepG2PPIG
chr116688695066887005+5'-UTR4.128235.47493HepG2BUD13
chr116688746766887521+5'-UTR,intron-Proximal4.427553.82000HepG2GRWD1
chr116701046067010537+5'-UTR,CDS,intron-Distal,intron-Proximal3.174115.67580HepG2U2AF2
chr116701045767010533+5'-UTR,CDS,intron-Distal,intron-Proximal3.598626.44666K562U2AF2
chr116688876766888834+5'-UTR,CDS,intron-Proximal3.574993.96535HepG2AQR
chr116701048667010559+5'-UTR,CDS,intron-Distal4.485233.79199HepG2PPIG
chr116701268167012900+5'-UTR,CDS5.8975918.67300HepG2GRWD1
chr116701042567010547+5'-UTR,CDS,intron-Distal,intron-Proximal5.0906710.03191K562SF3B4
chr116698333566983381+CDS5.134606.37937HepG2BCLAF1
chr116694768066947729+CDS,intron-Proximal4.283795.13243HepG2GRWD1
chr116699938266999471+CDS,intron-Proximal3.633944.83899HepG2PRPF8
chr116701777967017823+CDS,intron-Proximal4.653925.51215K562RBM15
chr116699922366999280+CDS3.975663.56019HepG2GRWD1
chr116698279766982851+CDS,intron-Proximal3.538674.41130K562AQR
chr116699907366999151+CDS3.282015.17903K562UCHL5
chr116701794567018003+CDS,intron-Distal3.411866.11449HepG2RBM15
chr116701755967017646+CDS4.101586.46803K562UCHL5
chr116694935666949397+CDS,intron-Proximal4.889943.70131HepG2PRPF8
chr116701344767013501+CDS,intron-Proximal3.950115.65086HepG2BCLAF1
chr116701341667013591+CDS,intron-Proximal3.407826.15340HepG2AQR
chr116694880966948875+CDS,intron-Proximal3.299455.30777HepG2PPIG
chr116699942166999478+CDS,intron-Proximal4.515953.85435K562PRPF8
chr116694929766949366+CDS,intron-Proximal3.404887.42773K562BUD13
chr116701292867013003+CDS,intron-Proximal4.092934.98250K562AQR
chr116694930866949395+CDS,intron-Proximal4.004596.35873K562PRPF8
chr116701812167018185+CDS,intron-Distal3.283825.91405HepG2BCLAF1
chr116701809067018176+CDS,intron-Distal4.005123.91585HepG2PRPF4
chr116701755167017628+CDS,intron-Proximal3.440956.64170K562BUD13
chr116694757966947662+CDS3.821415.15776HepG2BCLAF1
chr116701812467018181+CDS,intron-Distal4.002813.31335K562MTPAP
chr116701579067015850+CDS,intron-Proximal3.022023.95975HepG2BUD13
chr116694767466947722+CDS,intron-Proximal4.202926.75344HepG2EFTUD2
chr116697511066975162+CDS,intron-Proximal3.430563.28366HepG2BCLAF1
chr116701343667013518+CDS,intron-Proximal4.145826.98523HepG2U2AF2
chr116701578967015848+CDS,intron-Proximal3.188335.07297K562BUD13
chr116701579067015842+CDS,intron-Proximal4.359827.53358HepG2BCLAF1
chr116698338166983409+CDS4.377103.71570HepG2BCLAF1
chr116701353367013588+CDS,intron-Proximal3.072045.31654HepG2PPIG
chr116701288367012929+CDS3.217413.34848HepG2PPIG
chr116701577767015844+CDS,intron-Proximal3.395313.70975K562UCHL5
chr116698532266985353+CDS3.395613.61259K562ZNF622
chr116699920566999254+CDS3.367283.93112K562RBM15
chr116694881066948856+CDS3.003953.21309HepG2GRWD1
chr116701811767018181+CDS,intron-Distal4.411015.17013K562RBM15
chr116701796167017996+CDS,intron-Distal3.730326.49817K562RBM15
chr116694767966947753+CDS,intron-Proximal3.199637.13900K562AQR
chr116701811667018189+CDS,intron-Distal3.878153.35081HepG2G3BP1
chr116702009067020166+CDS,intron-Proximal4.376004.27476HepG2AQR
chr116701573867015790+CDS,intron-Proximal3.002164.81474HepG2BUD13
chr116701341167013481+CDS,intron-Proximal3.729085.83621K562AQR
chr116694766566947735+CDS,intron-Proximal5.0712617.64915K562GPKOW
chr116701344967013489+CDS,intron-Proximal4.186853.42472HepG2FXR2
chr116698286766982916+CDS3.357463.59112HepG2PPIG
chr116694766266947707+CDS,intron-Proximal3.450117.01246HepG2BCLAF1
chr116701826767018313+CDS,intron-Distal,intron-Proximal4.672064.86944K562AQR
chr116701794467017961+CDS,intron-Distal3.029414.86633K562RBM15
chr116701813167018219+CDS,intron-Distal3.442975.17903K562UCHL5
chr116701353867013586+CDS3.192203.13705K562BUD13
chr116701580467015879+CDS,intron-Proximal4.440998.44604HepG2PRPF8
chr116701574867015780+CDS,intron-Proximal3.049214.94718HepG2PPIG
chr116701816367018283+CDS,intron-Distal,intron-Proximal4.176057.77879K562TARDBP
chr116701755367017642+CDS,intron-Proximal4.781188.09084HepG2PPIG
chr116701577867015842+CDS,intron-Proximal4.835346.92104HepG2GRWD1
chr116694766666947734+CDS,intron-Proximal3.196057.53629K562BUD13
chr116698285466982917+CDS3.012845.39278K562ZNF622
chr116698528466985346+CDS3.198834.24070HepG2GRWD1
chr116697497566975011+CDS,intron-Proximal3.796205.29272K562BUD13
chr116701578767015845+CDS,intron-Proximal3.046143.75313HepG2FXR2
chr116701356967013626+CDS,intron-Proximal3.512475.34140HepG2PRPF8
chr116690741166907497+intron-Distal4.463135.37186HepG2ILF3
chr116700671767006844+intron-Distal5.096467.15660HepG2HNRNPM
chr116692607566926108+intron-Distal4.068453.59909K562EXOSC5
chr116697477466974884+intron-Distal,intron-Proximal3.233064.35650K562KHSRP
chr116692651566926559+intron-Distal4.375503.89085K562EXOSC5
chr116700813167008161+intron-Distal4.123094.66361K562XRN2
chr116694865366948732+intron-Distal,intron-Proximal3.546053.64762HepG2QKI
chr116692614466926206+intron-Distal4.583024.48560K562EXOSC5
chr116690920066909344+intron-Distal4.6784511.92269HepG2QKI
chr116699944066999611+intron-Distal,intron-Proximal3.437023.68839K562KHSRP
chr116690919166909243+intron-Distal4.359334.93238K562QKI
chr116700816167008179+intron-Distal4.101554.66361K562XRN2
chr116693599566936064+intron-Distal3.559445.63547HepG2HNRNPL
chr116700645567006546+intron-Distal4.616155.68226HepG2HNRNPM
chr116697823466978346+intron-Distal4.282714.58544K562ILF3
chr116700971067009817+intron-Distal3.620684.00200K562EIF4G2
chr116691578066915838+intron-Distal3.132583.19398HepG2XPO5
chr116693615166936214+intron-Distal4.427723.98095HepG2HNRNPL
chr116701042867010475+intron-Distal,intron-Proximal3.565463.57000HepG2BUD13
chr116701599867016092+intron-Distal,intron-Proximal3.731484.76004K562KHSRP
chr116702188967021935+intron-Proximal4.540078.52787K562AQR
chr116702108367021170+intron-Proximal3.646214.23459K562PRPF8
chr116702108267021171+intron-Proximal4.319795.63763K562AQR
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for KDM2A is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for KDM2A is not available on ENCORE database.

  • 78 RBPs can affect the levels of KDM2A.  








The Knockdown/knockout RNA-Seq assay for KDM2A is not available on ENCORE database.





78 RBPs can affect the gene expression of KDM2A :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
KDM2AENSG00000173120.101760.446702295.06980-0.382602.587202.07170HepG2AKAP1
KDM2AENSG00000173120.101537.463601898.90990-0.304602.036801.35900HepG2ASCC1
KDM2AENSG00000173120.101711.719401952.18780-0.189602.235501.62820HepG2CKAP4
KDM2AENSG00000173120.10586.54390871.40730-0.571105.051603.65740HepG2CSTF2
KDM2AENSG00000173120.102313.686702015.383300.199002.589301.86770HepG2DAZAP1
KDM2AENSG00000173120.103007.194102198.358100.451904.064703.31820HepG2DDX3X
KDM2AENSG00000173120.101689.722101420.394700.250403.333402.62990HepG2DNAJC2
KDM2AENSG00000173120.102433.206601815.387800.422503.540202.87350HepG2EIF2S1
KDM2AENSG00000173120.102408.629801904.697500.338602.906502.07290HepG2EIF4G2
KDM2AENSG00000173120.101953.281901409.369700.470805.283904.20750HepG2FUBP3
KDM2AENSG00000173120.10850.496201120.30080-0.397502.922401.99950HepG2GEMIN5
KDM2AENSG00000173120.102100.486901770.631200.246402.589701.89500HepG2HNRNPF
KDM2AENSG00000173120.101462.403301769.00150-0.274602.401301.51360HepG2HNRNPM
KDM2AENSG00000173120.101177.261801598.63880-0.441407.560906.59780HepG2HNRNPU
KDM2AENSG00000173120.102161.435701743.552600.309902.690301.97610HepG2IGF2BP1
KDM2AENSG00000173120.102669.708701908.627100.484004.713103.85240HepG2IGF2BP2
KDM2AENSG00000173120.101991.180302629.16810-0.401002.643501.83190HepG2LARP4
KDM2AENSG00000173120.101205.280102036.48290-0.756708.513407.45720HepG2MATR3
KDM2AENSG00000173120.102573.160602084.387900.303801.999501.45680HepG2NCBP2
KDM2AENSG00000173120.101206.365101582.38150-0.391405.643304.49350HepG2PARN
KDM2AENSG00000173120.102594.107102108.431600.299003.844303.26000HepG2RBM22
KDM2AENSG00000173120.101129.009301703.74100-0.593606.372204.86010HepG2RBM27
KDM2AENSG00000173120.101638.824202211.82590-0.432607.257606.45340HepG2NELFE
KDM2AENSG00000173120.101242.026301423.65980-0.196901.932001.37700HepG2SAFB2
KDM2AENSG00000173120.102917.757302007.365100.539506.860205.79040HepG2SF3B1
KDM2AENSG00000173120.102172.569301829.231900.248103.734702.93970HepG2SLBP
KDM2AENSG00000173120.101363.488201660.23010-0.284104.163603.40290HepG2SMN1
KDM2AENSG00000173120.101628.018502233.54700-0.456202.528201.78250HepG2SNRNP70
KDM2AENSG00000173120.103669.988502381.401000.6239021.2458020.19810HepG2SRFBP1
KDM2AENSG00000173120.101821.109702159.73600-0.246002.908802.42760HepG2SRSF1
KDM2AENSG00000173120.101494.773401883.60730-0.333604.571603.80170HepG2SRSF5
KDM2AENSG00000173120.102014.635101739.633700.211601.959701.36310HepG2SRSF7
KDM2AENSG00000173120.101389.283601941.48800-0.482807.143006.31490HepG2TAF15
KDM2AENSG00000173120.101053.113501567.26180-0.5736011.5523010.51680HepG2TRIM56
KDM2AENSG00000173120.102830.251102193.357200.367703.062402.40300HepG2U2AF1
KDM2AENSG00000173120.10594.06430815.66520-0.457403.149802.34090HepG2UCHL5
KDM2AENSG00000173120.101780.868102445.36780-0.4575010.174908.98320HepG2UPF1
KDM2AENSG00000173120.102116.330002513.48180-0.248103.004701.91870HepG2UTP18
KDM2AENSG00000173120.101983.931901677.383500.242003.271202.55160HepG2ZC3H8
KDM2AENSG00000173120.107000.892302447.948501.5159052.8912050.62890K562AQR
KDM2AENSG00000173120.101459.272401176.734900.310402.285701.34410K562CCAR1
KDM2AENSG00000173120.103901.579702831.086300.462602.305201.35240K562CNOT7
KDM2AENSG00000173120.101673.625301265.376100.403303.645302.09010K562DNAJC21
KDM2AENSG00000173120.101758.043101449.393800.278403.299401.96700K562EIF2S1
KDM2AENSG00000173120.102545.076201600.327300.669206.940605.20080K562EIF3D
KDM2AENSG00000173120.101546.270201076.876100.521807.839906.50550K562EIF3G
KDM2AENSG00000173120.102101.484401378.542400.608208.415006.98280K562EIF4A3
KDM2AENSG00000173120.101536.053401241.479700.307103.266101.98940K562EIF4B
KDM2AENSG00000173120.104317.725603199.682100.432209.069107.40650K562EIF4G2
KDM2AENSG00000173120.102041.065802460.55790-0.269702.147001.39730K562FIP1L1
KDM2AENSG00000173120.102958.575102390.028600.307802.247501.47360K562FMR1
KDM2AENSG00000173120.102195.937401433.631000.6151013.3408012.11240K562FXR1
KDM2AENSG00000173120.102671.805902116.356100.336104.400302.96530K562GLRX3
KDM2AENSG00000173120.102757.831202242.327900.298402.626801.85070K562GPKOW
KDM2AENSG00000173120.101998.595301451.139200.461705.595904.77680K562HNRNPC
KDM2AENSG00000173120.101591.081701295.790600.296102.416601.36330K562HNRNPF
KDM2AENSG00000173120.103020.171902527.341100.256902.249801.30650K562HNRNPL
KDM2AENSG00000173120.101548.301102023.78040-0.386402.869001.91890K562HNRNPM
KDM2AENSG00000173120.102191.373103336.08330-0.606308.628407.24130K562HSPD1
KDM2AENSG00000173120.103836.424102585.533400.569203.124801.60170K562ILF2
KDM2AENSG00000173120.101909.383101405.007700.442404.767402.87300K562LARP7
KDM2AENSG00000173120.101839.718701501.097700.293402.509401.70720K562MAGOH
KDM2AENSG00000173120.104422.684703410.613100.374804.107002.73040K562MSI2
KDM2AENSG00000173120.102661.270902225.051400.258202.589901.80600K562MTPAP
KDM2AENSG00000173120.102028.045601376.518200.559008.814006.65510K562NCBP2
KDM2AENSG00000173120.104493.273103499.749000.360404.055102.23390K562NOL12
KDM2AENSG00000173120.101647.631001335.555100.302902.438401.52330K562PCBP2
KDM2AENSG00000173120.101810.308901416.702000.353603.223601.66700K562PHF6
KDM2AENSG00000173120.102195.717602793.12830-0.347203.080102.20800K562PPIG
KDM2AENSG00000173120.103554.585202519.407100.496503.266301.31680K562PPIL4
KDM2AENSG00000173120.101850.236001454.667200.346902.621201.89070K562PRPF8
KDM2AENSG00000173120.101896.478901458.430900.378804.126203.33110K562PTBP1
KDM2AENSG00000173120.105046.268303491.151400.531408.191906.78600K562PUF60
KDM2AENSG00000173120.104447.434203712.985000.260302.823301.74350K562PUM1
KDM2AENSG00000173120.101793.105401398.311200.358703.119102.22210K562RBM22
KDM2AENSG00000173120.101451.996701186.958500.290702.481401.54680K562RCC2
KDM2AENSG00000173120.102495.364101967.533500.342803.428102.21770K562SAFB
KDM2AENSG00000173120.102794.274402132.942500.389502.436401.52890K562SF3B1
KDM2AENSG00000173120.101673.878801136.717200.558208.262706.74520K562SF3B4
KDM2AENSG00000173120.102916.960801904.845200.614702.533601.38020K562SNRNP200
KDM2AENSG00000173120.101517.832301125.215800.431704.098702.77740K562SRFBP1
KDM2AENSG00000173120.103158.967102499.205000.337907.010705.59540K562SRPK2
KDM2AENSG00000173120.101785.216201429.779300.320202.945002.21860K562SRSF1
KDM2AENSG00000173120.101858.912301408.166200.400502.917901.87180K562SUPV3L1
KDM2AENSG00000173120.102005.204401446.963600.470604.645303.72130K562TARDBP
KDM2AENSG00000173120.101333.415401094.484900.284802.365601.62320K562U2AF2
KDM2AENSG00000173120.103542.874202900.372200.288602.802201.50090K562WRN
KDM2AENSG00000173120.103688.657302757.693200.419504.851503.66050K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for KDM2A is not available on ENCORE database.





3 RBPs can affect the splicing of KDM2A :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEKDM2AENSG00000173120.10chr11+6689942266899544668887046688882966947549669479240.207000.000000.00065includedK562HNRNPM
SEKDM2AENSG00000173120.10chr11+6689942266899544668887046688882966947549669479240.066000.000160.04817includedHepG2CDC40
A3SSKDM2AENSG00000173120.10chr11+6701342367013587670134556701358767012659670129290.065000.000080.00067longerK562AQR
A3SSKDM2AENSG00000173120.10chr11+6702013867020328670201646702032867017556670182690.066000.000170.00141longerK562AQR
A5SSKDM2AENSG00000173120.10chr11+6701575167015972670157516701584167017556670182690.084000.000070.00185longerK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for KDM2A is not avaliable on ENCORE database.