HMGXB4

General Information

Gene Name       : HMGXB4
Gene ID             : ENSG00000100281.13
Essential Gene : No

Functions

Localization

Domains (AlphaFold: HMGXB4)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878HMGXB4ENSG00000100281.1324.9122.4223.66ENCSR000AEF
HepG2HMGXB4ENSG00000100281.138.7713.6611.21ENCSR985KAT
K562HMGXB4ENSG00000100281.1317.0917.8617.48ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for HMGXB4 is not avaliable on ENCORE database.



Proteins bound to RNA
  • HMGXB4 RNA is bound by 15 proteins.  







eCLIP assay for HMGXB4 is not avaliable on ENCORE database.





15 proteins are bound to HMGXB4 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr223567996035680037+3'-UTR,CDS,intron-Proximal5.018067.60619K562UCHL5
chr223566064135660701+3'-UTR,5'-UTR,CDS3.772786.15459HepG2GRWD1
chr223567989635680011+3'-UTR,CDS,intron-Proximal4.338965.94114HepG2BUD13
chr223565979435659860+3'-UTR,5'-UTR,CDS4.844365.03746HepG2BCLAF1
chr223565915535659219+3'-UTR,5'-UTR,CDS3.973956.46803K562UCHL5
chr223569171135691746+3'-UTR5.643995.76336K562PUM2
chr223565986035659923+3'-UTR,5'-UTR,CDS,intron-Proximal4.986074.86944K562AQR
chr223565915535659208+3'-UTR,5'-UTR,CDS3.957764.04622HepG2GRWD1
chr223569110535691214+3'-UTR4.374364.12025K562YBX3
chr223565916035659215+3'-UTR,5'-UTR,CDS3.422593.57857HepG2BCLAF1
chr223569077435690856+3'-UTR4.3649110.51380K562PCBP1
chr223568980635689861+3'-UTR5.8515111.85849K562PUM2
chr223569160035691668+3'-UTR5.5377817.95513K562PUM2
chr223569077435690881+3'-UTR6.6100230.52366HepG2PCBP2
chr223566069435660777+3'-UTR,5'-UTR,CDS3.359826.74947HepG2BCLAF1
chr223569155635691597+3'-UTR4.509037.91848K562PUM2
chr223566070135660774+3'-UTR,5'-UTR,CDS3.117964.09398HepG2GRWD1
chr223569079135690888+3'-UTR3.8791213.22424K562ILF3
chr223569078635690872+3'-UTR3.269585.37771HepG2PTBP1
chr223566004035660063+3'-UTR,5'-UTR,intron-Distal4.040583.36385K562UCHL5
chr223565907035659130+3'-UTR,5'-UTR,CDS,intron-Proximal3.098875.66840K562ZNF622
chr223568198735682044+3'-UTR,CDS,intron-Proximal3.872203.28461K562BUD13
chr223566070535660776+3'-UTR,5'-UTR,CDS3.360018.15127K562ZNF622
chr223566070735660773+3'-UTR,5'-UTR,CDS4.255787.16955K562UCHL5
chr223566141135661493+5'-UTR,CDS3.197127.36807K562UCHL5
chr223566097935661069+5'-UTR,CDS3.220374.02291HepG2GRWD1
chr223566132835661411+5'-UTR,CDS3.331784.30396K562UCHL5
chr223565352535653594+5'-UTR,intron-Proximal3.648513.71591HepG2PRPF8
chr223566139335661466+5'-UTR,CDS3.788664.51739HepG2BCLAF1
chr223566133735661453+5'-UTR,CDS4.083854.02380K562TRA2A
chr223565374835653912+intron-Distal4.110413.70701HepG2PRPF4
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for HMGXB4 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for HMGXB4 is not available on ENCORE database.

  • 73 RBPs can affect the levels of HMGXB4.  








The Knockdown/knockout RNA-Seq assay for HMGXB4 is not available on ENCORE database.





73 RBPs can affect the gene expression of HMGXB4 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
HMGXB4ENSG00000100281.9535.21690397.550600.428902.549001.51720HepG2AATF
HMGXB4ENSG00000100281.9916.98080631.609100.537803.541902.94960HepG2AKAP1
HMGXB4ENSG00000100281.9383.94280522.59190-0.444802.423001.68270HepG2ASCC1
HMGXB4ENSG00000100281.9687.44690904.29240-0.395504.457803.62280HepG2AUH
HMGXB4ENSG00000100281.9310.53250506.50960-0.705804.379403.19790HepG2BCCIP
HMGXB4ENSG00000100281.9308.90880440.12040-0.510702.685101.79820HepG2BCLAF1
HMGXB4ENSG00000100281.9318.62950697.36510-1.1300014.8016013.56880HepG2BOP1
HMGXB4ENSG00000100281.9345.50610506.14260-0.550805.556704.67390HepG2CKAP4
HMGXB4ENSG00000100281.9352.86810458.80790-0.378802.374101.43510HepG2YBX3
HMGXB4ENSG00000100281.9370.95560468.21620-0.335902.492801.69780HepG2DDX19B
HMGXB4ENSG00000100281.9363.54590498.00250-0.454002.119801.43400HepG2DDX55
HMGXB4ENSG00000100281.9446.54620593.88950-0.411402.492001.52820HepG2DDX5
HMGXB4ENSG00000100281.9369.97670484.35420-0.388602.705702.03500HepG2DKC1
HMGXB4ENSG00000100281.9603.37150740.85010-0.296102.234601.46800HepG2EIF4G1
HMGXB4ENSG00000100281.9485.56520709.67910-0.547504.253603.25820HepG2EIF4G2
HMGXB4ENSG00000100281.9809.320101038.29620-0.359403.741003.05930HepG2ETF1
HMGXB4ENSG00000100281.9377.36700725.79830-0.943608.995907.88540HepG2GPKOW
HMGXB4ENSG00000100281.9344.99780454.82080-0.398702.114201.54130HepG2HNRNPA1
HMGXB4ENSG00000100281.9462.07190609.37440-0.399203.336202.55460HepG2HNRNPF
HMGXB4ENSG00000100281.9440.28280692.63890-0.653705.235004.39890HepG2HNRNPLL
HMGXB4ENSG00000100281.9474.81870600.06100-0.337702.206601.55550HepG2IGF2BP1
HMGXB4ENSG00000100281.9316.33290525.27800-0.731605.656704.72380HepG2IGF2BP2
HMGXB4ENSG00000100281.9404.86600513.35160-0.342502.747302.01700HepG2ILF2
HMGXB4ENSG00000100281.9520.07030738.60130-0.506102.930702.07520HepG2LARP4
HMGXB4ENSG00000100281.9347.58310560.43420-0.689204.639703.83960HepG2MATR3
HMGXB4ENSG00000100281.9348.97330509.56690-0.546202.715401.68580HepG2PCBP2
HMGXB4ENSG00000100281.9495.98930636.30270-0.359403.017002.21430HepG2PRPF4
HMGXB4ENSG00000100281.9651.35150506.166700.363702.981402.41720HepG2PTBP1
HMGXB4ENSG00000100281.9399.64990710.79120-0.830709.431308.42040HepG2PUF60
HMGXB4ENSG00000100281.9783.03930548.141300.514405.123604.31380HepG2QKI
HMGXB4ENSG00000100281.9718.42420491.823600.546602.378601.72170HepG2RAVER1
HMGXB4ENSG00000100281.9554.50830867.81360-0.646208.443207.65310HepG2RBM22
HMGXB4ENSG00000100281.9437.29200656.42780-0.586003.461302.71060HepG2RPLP0
HMGXB4ENSG00000100281.9398.29470571.42520-0.520703.401002.51500HepG2RPS2
HMGXB4ENSG00000100281.9317.36140511.00350-0.687204.157103.17620HepG2RPS3A
HMGXB4ENSG00000100281.9534.86710685.60010-0.358202.100701.48010HepG2SF3B1
HMGXB4ENSG00000100281.9550.39020681.57190-0.308402.378101.72100HepG2SLBP
HMGXB4ENSG00000100281.9425.56960521.91690-0.294402.073601.50470HepG2SMN1
HMGXB4ENSG00000100281.9386.77500762.84160-0.979905.387504.28710HepG2SNRNP70
HMGXB4ENSG00000100281.9744.04960550.031500.435804.288003.73080HepG2SRSF1
HMGXB4ENSG00000100281.9487.63820701.82260-0.525305.624404.77810HepG2SRSF5
HMGXB4ENSG00000100281.9452.89060598.68610-0.402603.440802.67670HepG2SRSF7
HMGXB4ENSG00000100281.9486.17560850.96820-0.8076014.5452013.55660HepG2SSB
HMGXB4ENSG00000100281.9264.36800495.75670-0.907106.670405.69200HepG2SUPV3L1
HMGXB4ENSG00000100281.9637.35450494.437200.366202.840302.27260HepG2TAF15
HMGXB4ENSG00000100281.9481.45220674.99590-0.487503.427102.63020HepG2TARDBP
HMGXB4ENSG00000100281.9592.62360454.270100.383502.784701.94660HepG2TIA1
HMGXB4ENSG00000100281.9239.23570488.31610-1.0294012.4865011.55650HepG2TIAL1
HMGXB4ENSG00000100281.9277.13290492.70130-0.8301010.563209.56720HepG2TRIM56
HMGXB4ENSG00000100281.9538.92080694.43990-0.365802.389701.58180HepG2TUFM
HMGXB4ENSG00000100281.9185.15800292.86070-0.661503.592302.73010HepG2UCHL5
HMGXB4ENSG00000100281.9415.49050518.25530-0.318802.264601.62230HepG2UPF1
HMGXB4ENSG00000100281.9393.77200532.70150-0.436003.483902.32290HepG2UTP18
HMGXB4ENSG00000100281.9287.16350488.01800-0.765105.376204.37580HepG2XRN2
HMGXB4ENSG00000100281.9455.90690627.96660-0.461904.817203.97240HepG2ZC3H8
HMGXB4ENSG00000100281.9443.09880569.98300-0.363303.149202.57800HepG2ZNF622
HMGXB4ENSG00000100281.9804.11620960.85500-0.256901.917601.42890K562AGGF1
HMGXB4ENSG00000100281.9748.31630999.79540-0.418003.528702.78750K562AKAP8L
HMGXB4ENSG00000100281.9975.995701200.42070-0.298603.125702.43900K562DDX47
HMGXB4ENSG00000100281.9795.46630569.611900.481703.981402.99990K562EIF4A3
HMGXB4ENSG00000100281.9871.38120668.851900.381501.941901.36140K562G3BP2
HMGXB4ENSG00000100281.9847.028401158.15870-0.451404.189703.26220K562GRSF1
HMGXB4ENSG00000100281.9676.40840843.85530-0.319102.990202.15070K562MTPAP
HMGXB4ENSG00000100281.9680.48840892.97670-0.392102.466501.68260K562PCBP3
HMGXB4ENSG00000100281.9515.98130684.92600-0.408603.278702.40190K562POLR2G
HMGXB4ENSG00000100281.92046.608801621.357100.335903.714302.46280K562PUM1
HMGXB4ENSG00000100281.9694.84820991.64990-0.513104.601003.92360K562PUS1
HMGXB4ENSG00000100281.9762.49180966.10800-0.341503.071302.45220K562RBM15
HMGXB4ENSG00000100281.9604.04780787.74980-0.383102.715801.88320K562RBM22
HMGXB4ENSG00000100281.9597.47980828.99830-0.472503.663302.38380K562NELFE
HMGXB4ENSG00000100281.9427.67700581.17640-0.442502.281001.54230K562RPS19
HMGXB4ENSG00000100281.9533.17230695.62020-0.383702.967302.08060K562SF3B4
HMGXB4ENSG00000100281.9867.81230687.023000.336902.653801.85230K562SYNCRIP
HMGXB4ENSG00000100281.9931.27690669.693400.475604.904403.83620K562U2AF2
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for HMGXB4 is not available on ENCORE database.





16 RBPs can affect the splicing of HMGXB4 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEHMGXB4ENSG00000100281.9chr22+356599743566008935659788356598673566064035661596-0.321000.000090.00279excludedK562SF3B4
SEHMGXB4ENSG00000100281.9chr22+356889843568910735684230356844003568959935689762-0.272000.000000.00001excludedK562SF3B4
SEHMGXB4ENSG00000100281.9chr22+3565831535658414356534793565355035659070356592190.295000.006550.09350includedHepG2U2AF1
SEHMGXB4ENSG00000100281.9chr22+356583153565841435653479356535503565907035659219-0.273000.000300.01195excludedK562AKAP8L
SEHMGXB4ENSG00000100281.9chr22+3565831535658414356534793565355035659070356592190.483000.000430.05644includedHepG2HNRNPM
SEHMGXB4ENSG00000100281.9chr22+3565831535658414356534793565355035659070356592190.321000.000000.00086includedHepG2AKAP1
SEHMGXB4ENSG00000100281.9chr22+3565831535658414356534793565355035659070356592190.227000.001620.09527includedHepG2DDX3X
SEHMGXB4ENSG00000100281.9chr22+3565997435660089356597883565986735660640356615960.279000.000380.03576includedK562SUPV3L1
SEHMGXB4ENSG00000100281.9chr22+356583153565841435653479356535503565907035659219-0.294000.000900.01564excludedK562PUS1
SEHMGXB4ENSG00000100281.9chr22+3565831535658414356534793565355035659070356592190.279000.000800.03650includedHepG2MATR3
SEHMGXB4ENSG00000100281.9chr22+356599743566008935659788356598673566064035661596-0.206000.004120.07019excludedK562U2AF1
SEHMGXB4ENSG00000100281.9chr22+356599743566008935659788356598673566064035661596-0.399000.000000.00002excludedHepG2SF3A3
SEHMGXB4ENSG00000100281.9chr22+356599743566008935659788356598673566064035661596-0.353000.000000.00001excludedK562U2AF2
SEHMGXB4ENSG00000100281.9chr22+356583153565841435653479356535503565907035659219-0.252000.001740.04244excludedK562AGGF1
SEHMGXB4ENSG00000100281.9chr22+356599743566008935659788356598673566064035661596-0.596000.000000.00001excludedHepG2HNRNPU
SEHMGXB4ENSG00000100281.9chr22+356599743566008935659788356598673566064035661596-0.474000.000050.00362excludedHepG2HNRNPC
SEHMGXB4ENSG00000100281.9chr22+3565831535658414356534793565355035659070356592190.281000.000350.05227includedHepG2KHSRP
MXEHMGXB4ENSG00000100281.9chr22+3568423035684400356889843568910735683339356834453568959935691757-0.121000.002470.034332includedK562DROSHA

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for HMGXB4 is not avaliable on ENCORE database.