HEPH

General Information

Gene Name       : HEPH
Gene ID             : ENSG00000089472.16
Essential Gene : No

Functions

Localization

Domains (AlphaFold: HEPH)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878HEPHENSG00000089472.160.600.210.40ENCSR000AEF
HepG2HEPHENSG00000089472.160.000.010.01ENCSR985KAT
K562HEPHENSG00000089472.1628.5730.0329.30ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for HEPH is not avaliable on ENCORE database.



Proteins bound to RNA
  • HEPH RNA is bound by 28 proteins.  







eCLIP assay for HEPH is not avaliable on ENCORE database.





28 proteins are bound to HEPH RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chrX6548652965486564+3'-UTR4.1712513.84651K562YBX3
chrX6548699865487099+3'-UTR5.494718.02915HepG2SUB1
chrX6548670965486775+3'-UTR3.365308.82673K562TIA1
chrX6539214265392214+3'-UTR,5'-UTR,CDS,intron-Proximal3.914789.48554K562SF3B4
chrX6548713265487212+3'-UTR4.118638.74435HepG2SUB1
chrX6548657065486602+3'-UTR3.686538.91050K562YBX3
chrX6538271665382814+5'-UTR,CDS,intron-Proximal3.9959512.56301K562AQR
chrX6538976565389847+5'-UTR,intron-Distal3.8844720.15775K562KHSRP
chrX6539359865393640+5'-UTR,CDS3.211916.10587K562SND1
chrX6538984865389872+5'-UTR,intron-Distal3.869577.69621K562KHSRP
chrX6540826665408393+5'-UTR,CDS,intron-Proximal3.364596.19253K562GRWD1
chrX6539342665393494+5'-UTR,CDS,intron-Proximal3.564918.16546K562BUD13
chrX6540826165408322+5'-UTR,CDS4.559255.23082K562DDX24
chrX6539231265392377+5'-UTR,CDS3.378339.46864K562UCHL5
chrX6539236265392425+5'-UTR,CDS3.5929811.24658K562YBX3
chrX6538255965382647+5'-UTR,CDS3.243924.32969K562DDX3X
chrX6538248965382559+5'-UTR3.587244.84203K562DDX3X
chrX6538257765382637+5'-UTR,CDS3.497344.51666K562RBM15
chrX6539343265393479+5'-UTR,CDS3.367555.77413K562DDX24
chrX6540832465408384+5'-UTR,CDS,intron-Proximal4.319439.70241K562ZNF622
chrX6538250965382554+5'-UTR3.560113.77784K562RBM15
chrX6539350965393570+5'-UTR,CDS3.229546.62505K562UCHL5
chrX6542321165423260+CDS4.562699.84629K562SND1
chrX6542039065420488+CDS,intron-Distal3.660278.59884K562SND1
chrX6542048865420561+CDS,intron-Distal4.1225710.76840K562SND1
chrX6542795665428019+CDS,intron-Proximal3.189484.85261K562DDX24
chrX6541491165414965+CDS,intron-Proximal3.138504.83230K562AQR
chrX6547487665474893+CDS,intron-Proximal5.002945.54797K562SND1
chrX6541868465418722+CDS,intron-Distal,intron-Proximal4.623634.09264K562AQR
chrX6541197165412047+CDS,intron-Proximal4.2586220.95691K562SND1
chrX6548638965486414+CDS3.936716.46034K562SND1
chrX6541208365412103+CDS4.517395.22159K562SND1
chrX6547496165474982+CDS4.643165.22159K562SND1
chrX6540953265409596+CDS4.077969.54710K562SND1
chrX6541886865418914+CDS,intron-Distal,intron-Proximal4.874885.69951K562AQR
chrX6541345065413479+CDS3.376694.17944K562BUD13
chrX6542326965423317+CDS4.492635.82137K562YBX3
chrX6541874865418791+CDS,intron-Distal4.130226.77664K562SND1
chrX6541768365417723+CDS,intron-Distal3.603354.74268K562UCHL5
chrX6540952665409585+CDS3.434856.11414K562BUD13
chrX6540838265408428+CDS,intron-Proximal3.784594.52312K562AQR
chrX6547615565476230+CDS,intron-Proximal4.919626.15361K562PRPF8
chrX6542712865427164+CDS4.870764.17466K562DDX24
chrX6541769465417726+CDS,intron-Distal4.594594.90367K562ZNF622
chrX6542335265423415+CDS3.325198.46648K562DDX24
chrX6542703565427082+CDS,intron-Proximal3.785805.20093K562DDX24
chrX6540970165409751+CDS3.348123.13141K562RBM15
chrX6547866865478745+CDS,intron-Proximal3.391814.86522K562U2AF2
chrX6542711665427173+CDS4.549588.55362K562SND1
chrX6542326865423315+CDS3.432434.50206K562SND1
chrX6542711665427185+CDS,intron-Proximal3.156063.23249K562SRSF1
chrX6541488165414983+CDS,intron-Proximal3.7144910.24099K562SF3B4
chrX6542332965423419+CDS3.529154.56136K562GRWD1
chrX6542335865423414+CDS3.255785.71803K562UCHL5
chrX6541768465417724+CDS,intron-Distal5.189729.18911K562SND1
chrX6547594865475992+CDS4.365559.16010K562SND1
chrX6541493065414977+CDS,intron-Proximal3.433406.69476K562BUD13
chrX6541773565417745+CDS,intron-Distal,intron-Proximal4.221836.48405K562AQR
chrX6542796765428042+CDS4.660183.66349K562LIN28B
chrX6548352965483620+CDS,intron-Proximal6.0069813.28065K562AQR
chrX6542799865428089+CDS,intron-Proximal6.4124320.35631K562SND1
chrX6541205865412140+CDS5.9956813.70562K562LIN28B
chrX6540961865409682+CDS3.718448.65309K562SND1
chrX6542712965427177+CDS,intron-Proximal3.425847.21479K562UCHL5
chrX6540976665409779+CDS3.028753.68647K562SND1
chrX6540968265409747+CDS3.369297.35442K562SND1
chrX6542796465428050+CDS3.180724.24058K562GRWD1
chrX6544472865444855+intron-Distal6.1978660.48105K562PTBP1
chrX6539601565396096+intron-Distal3.299503.43875K562EXOSC5
chrX6541782365417953+intron-Distal,intron-Proximal3.351265.34873K562KHSRP
chrX6547126665471346+intron-Distal4.042233.25538K562KHSRP
chrX6545735965457506+intron-Distal7.1917839.56674K562EXOSC5
chrX6543559665435652+intron-Distal4.486334.48994K562RBM15
chrX6543542665435557+intron-Distal4.0379812.01684K562SAFB2
chrX6539059165390662+intron-Distal,intron-Proximal5.3539410.90574K562EFTUD2
chrX6543539065435476+intron-Distal3.695093.08967K562KHDRBS1
chrX6545532565455388+intron-Distal4.254727.61465K562EXOSC5
chrX6545507165455098+intron-Distal4.904957.38693K562EXOSC5
chrX6544468165444728+intron-Distal4.3823211.65716K562PTBP1
chrX6543497265435035+intron-Distal3.258856.67026K562KHSRP
chrX6539453565394578+intron-Distal4.214543.89085K562EXOSC5
chrX6538917565389211+intron-Distal3.067729.07932K562TARDBP
chrX6539136365391442+intron-Distal3.738155.79195K562CSTF2T
chrX6541844465418516+intron-Distal3.176603.26015K562PTBP1
chrX6541799865418076+intron-Distal3.246994.50771K562PTBP1
chrX6546160265461698+intron-Distal4.507435.62266K562SAFB2
chrX6545650565456583+intron-Distal5.0149922.52837K562EXOSC5
chrX6543465565434721+intron-Distal3.345624.72639K562KHSRP
chrX6539563365395697+intron-Distal4.486703.59909K562EXOSC5
chrX6538484965384947+intron-Distal3.458344.49507K562ILF3
chrX6545615665456199+intron-Distal4.097306.10949K562EXOSC5
chrX6539057965390642+intron-Distal,intron-Proximal5.342337.28294K562AQR
chrX6545783165457910+intron-Distal6.5047621.00970K562EXOSC5
chrX6543700165437119+intron-Distal3.224195.74046K562SAFB2
chrX6538880265388841+intron-Distal5.1576320.12825K562TARDBP
chrX6546581965465989+intron-Distal5.219415.04680K562HNRNPM
chrX6545766765457713+intron-Distal5.063835.44433K562EXOSC5
chrX6547465665474749+intron-Distal3.012753.55860K562SAFB2
chrX6538967365389734+intron-Distal3.008957.89500K562KHSRP
chrX6539066265390700+intron-Distal,intron-Proximal4.211774.36481K562EFTUD2
chrX6543834265438409+intron-Distal3.946124.07784K562SAFB2
chrX6544776965447875+intron-Distal5.023589.67261K562SAFB2
chrX6545569265455751+intron-Distal6.0798616.98921K562EXOSC5
chrX6538886165388905+intron-Distal3.9848013.98902K562TARDBP
chrX6538561465385644+intron-Distal3.302084.41421K562PTBP1
chrX6545449365454539+intron-Distal4.651775.76685K562EXOSC5
chrX6538716865387260+intron-Distal3.2844510.35541K562KHSRP
chrX6539190265392003+intron-Distal4.287884.96658K562KHSRP
chrX6546595365466101+intron-Distal3.761503.43228K562SAFB2
chrX6539502565395083+intron-Distal3.581214.61337K562EXOSC5
chrX6538747965387605+intron-Distal5.218929.32163K562TARDBP
chrX6545599665456073+intron-Distal4.689963.53404K562HNRNPM
chrX6543508165435198+intron-Distal4.2645915.45584K562KHSRP
chrX6543627265436326+intron-Distal4.003413.10243K562SLTM
chrX6543133365431413+intron-Distal3.107334.41351K562PTBP1
chrX6538884165388861+intron-Distal5.7784115.37751K562TARDBP
chrX6538872365388766+intron-Distal6.2664219.88805K562TARDBP
chrX6546614565466249+intron-Distal4.385064.48623K562EXOSC5
chrX6541774565417780+intron-Distal,intron-Proximal4.331156.99120K562AQR
chrX6545897665459039+intron-Distal4.097303.01445K562EXOSC5
chrX6538566765385711+intron-Distal5.513249.66407K562PTBP1
chrX6542121165421313+intron-Distal5.2713218.09984K562PTBP1
chrX6541799465418106+intron-Distal4.718609.90978K562ILF3
chrX6538571665385772+intron-Distal4.7823324.69450K562PTBP1
chrX6538926165389340+intron-Distal3.7949713.58062K562TARDBP
chrX6545826965458307+intron-Distal3.743984.91094K562EXOSC5
chrX6545666565456711+intron-Distal6.0159816.98921K562EXOSC5
chrX6539058365390665+intron-Distal,intron-Proximal4.1836413.06913K562PRPF8
chrX6542859365428668+intron-Distal3.529357.09496K562ILF3
chrX6538921165389246+intron-Distal3.9140913.52621K562TARDBP
chrX6545511465455151+intron-Distal4.607845.12361K562EXOSC5
chrX6538876665388802+intron-Distal4.8052919.45130K562TARDBP
chrX6545694165456974+intron-Distal4.097306.10949K562EXOSC5
chrX6546015065460220+intron-Distal3.805243.43228K562SAFB2
chrX6545699265457037+intron-Distal4.360316.41051K562EXOSC5
chrX6548357465483661+intron-Distal,intron-Proximal3.692764.58287K562PRPF8
chrX6545658565456631+intron-Distal6.4937520.67406K562EXOSC5
chrX6539364965393729+intron-Proximal4.077075.63763K562AQR
chrX6542314165423186+intron-Proximal4.785683.91589K562SF3B4
chrX6541507865415133+intron-Proximal4.792564.86944K562AQR
chrX6541484765414908+intron-Proximal3.622804.22415K562PTBP1
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for HEPH is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for HEPH is not available on ENCORE database.

  • 53 RBPs can affect the levels of HEPH.  








The Knockdown/knockout RNA-Seq assay for HEPH is not available on ENCORE database.





53 RBPs can affect the gene expression of HEPH :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
HEPHENSG00000089472.1211.864400.0000099999.999902.890601.96970HepG2BCLAF1
HEPHENSG00000089472.124627.869303259.484300.505606.439304.58110K562ABCF1
HEPHENSG00000089472.122925.550802284.075400.357005.563303.35330K562AKAP1
HEPHENSG00000089472.121834.910704231.70070-1.2055030.2642028.52410K562AQR
HEPHENSG00000089472.123366.006401643.013301.0346020.7807018.41640K562BOP1
HEPHENSG00000089472.127694.528805752.532700.419506.693904.84350K562CCDC124
HEPHENSG00000089472.123107.032401746.901500.8306019.0892017.02060K562CPSF6
HEPHENSG00000089472.124340.553606365.49800-0.5524011.931609.98240K562CELF1
HEPHENSG00000089472.123031.754102452.287400.305904.331702.06520K562DDX24
HEPHENSG00000089472.124191.546003657.981600.196302.418101.80360K562DDX47
HEPHENSG00000089472.123058.674305389.90490-0.8174028.7093025.54220K562DKC1
HEPHENSG00000089472.121495.839402216.37880-0.567206.564405.11070K562EFTUD2
HEPHENSG00000089472.123029.714502542.198800.253003.437102.07500K562EIF2S1
HEPHENSG00000089472.124228.569002879.223500.5544013.3755011.97610K562EIF2S2
HEPHENSG00000089472.121696.141202417.97880-0.511506.276705.04820K562EIF4A3
HEPHENSG00000089472.123138.674302102.960800.577606.472404.61500K562FKBP4
HEPHENSG00000089472.122555.041601777.611000.523306.127004.84160K562FMR1
HEPHENSG00000089472.122313.488701506.763900.618507.016105.48980K562FTO
HEPHENSG00000089472.121943.373802514.59910-0.371805.588004.76970K562FXR1
HEPHENSG00000089472.122233.128002775.34320-0.313603.957902.60030K562GLRX3
HEPHENSG00000089472.123107.818703836.70050-0.304003.276202.45620K562GRSF1
HEPHENSG00000089472.122505.230603157.55660-0.333903.675402.43530K562HNRNPA1
HEPHENSG00000089472.122153.118603496.66720-0.6996017.6788015.54180K562HNRNPU
HEPHENSG00000089472.121949.612101424.276900.452902.969001.99720K562KRR1
HEPHENSG00000089472.122215.684603388.47320-0.612909.869208.21820K562MAGOH
HEPHENSG00000089472.124228.680105088.16010-0.266902.301401.35020K562MAK16
HEPHENSG00000089472.122714.779003381.54220-0.316803.392502.35630K562MATR3
HEPHENSG00000089472.122120.736801627.977200.381403.789802.75320K562METAP2
HEPHENSG00000089472.124192.838905662.50890-0.433505.526903.36790K562NOL12
HEPHENSG00000089472.123603.943803241.997800.152602.421501.71880K562NSUN2
HEPHENSG00000089472.122569.883803312.39910-0.366204.483302.72710K562PCBP1
HEPHENSG00000089472.121830.774103014.83380-0.7196012.4792010.31780K562PCBP2
HEPHENSG00000089472.122257.503503036.40310-0.427603.759602.78920K562PCBP3
HEPHENSG00000089472.121893.467902329.10540-0.298702.986302.15380K562POLR2G
HEPHENSG00000089472.121015.671202156.79270-1.0865020.7833018.72340K562PRPF8
HEPHENSG00000089472.121389.704102171.56500-0.644009.166607.32330K562PSIP1
HEPHENSG00000089472.122222.280603292.14180-0.567009.549808.36960K562PTBP1
HEPHENSG00000089472.122039.722105647.99180-1.4694049.3805045.95140K562PUF60
HEPHENSG00000089472.121568.919802299.15950-0.551303.372201.77500K562RAVER1
HEPHENSG00000089472.123551.432504839.80580-0.446508.415507.40740K562RBM15
HEPHENSG00000089472.122730.568203638.70620-0.414205.423903.19190K562RBM17
HEPHENSG00000089472.122318.980803156.56670-0.444905.024303.85230K562RBM22
HEPHENSG00000089472.121595.273802196.90990-0.461703.513102.58960K562RPS19
HEPHENSG00000089472.121586.174602075.03590-0.387604.020902.70570K562SAFB
HEPHENSG00000089472.121924.780802505.00470-0.380104.933003.77710K562SF3B4
HEPHENSG00000089472.122120.609003544.83250-0.741203.449802.02370K562SNRNP200
HEPHENSG00000089472.122251.024403227.43860-0.519808.070306.87220K562SRSF1
HEPHENSG00000089472.121943.379602336.04190-0.265502.513801.73290K562SYNCRIP
HEPHENSG00000089472.122119.072203266.28800-0.624208.405807.08690K562TARDBP
HEPHENSG00000089472.121532.964102088.67050-0.446303.836102.72750K562TIAL1
HEPHENSG00000089472.123919.707602411.870300.7005015.7089013.76660K562U2AF2
HEPHENSG00000089472.122908.385702210.120300.396003.617002.44080K562UCHL5
HEPHENSG00000089472.124744.798203437.565300.4649012.7732011.36720K562UPF1
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for HEPH is not available on ENCORE database.





12 RBPs can affect the splicing of HEPH :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEHEPHENSG00000089472.12chrX+653903996539057965382390653827186539219665392441-0.055000.001770.03321excludedK562SRSF1
SEHEPHENSG00000089472.12chrX+654759466547617265474876654749836547868165478821-0.168000.000000.00007excludedK562SRSF1
SEHEPHENSG00000089472.12chrX+654759466547617265474876654749836547868165478821-0.068000.004880.07273excludedK562SF3B4
SEHEPHENSG00000089472.12chrX+654759466547617265427956654280886547868165478821-0.230000.002240.06747excludedK562PRPF8
SEHEPHENSG00000089472.12chrX+654786816547882165427956654280886547994165480104-0.068000.000050.00086excludedK562AQR
SEHEPHENSG00000089472.12chrX+654748766547498365427956654280886547868165478892-0.210000.002800.03962excludedK562PUS1
SEHEPHENSG00000089472.12chrX+654119716541214065409525654097806541334365413480-0.153000.000010.00102excludedK562EFTUD2
SEHEPHENSG00000089472.12chrX+654759466547617265474876654749836547868165478821-0.117000.001060.05321excludedK562EFTUD2
SEHEPHENSG00000089472.12chrX+6538419465384312653824326538271865390399653905790.224000.000680.01643includedK562U2AF1
SEHEPHENSG00000089472.12chrX+6538419465384312653824326538271865390399653905790.168000.001180.02306includedK562U2AF2
SEHEPHENSG00000089472.12chrX+654119716541214065409525654097806541334365413480-0.066000.002150.06698excludedK562TARDBP
SEHEPHENSG00000089472.12chrX+654748766547498365427956654280886547868165478892-0.277000.000700.02072excludedK562RBM15
SEHEPHENSG00000089472.12chrX+654204156542059465418719654188706542320565423419-0.054000.002870.06038excludedK562RBM15
SEHEPHENSG00000089472.12chrX+6548200565482183654799416548010465483485654835300.096000.000000.00001includedK562SF3B1
A3SSHEPHENSG00000089472.12chrX+6541752465417736654176536541773665414939654150710.070000.000210.02524longerK562AGGF1
A3SSHEPHENSG00000089472.12chrX+654203816542059465420415654205946541871965418870-0.259000.000010.00323shorterK562EFTUD2
A3SSHEPHENSG00000089472.12chrX+654203816542059465420415654205946541871965418870-0.117000.016740.08206shorterK562AQR
A3SSHEPHENSG00000089472.12chrX+654175246541773665417653654177366541493965415071-0.251000.000000.00009shorterK562SRSF1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for HEPH is not avaliable on ENCORE database.