FBXO6

General Information

Gene Name       : FBXO6
Gene ID             : ENSG00000116663.10
Essential Gene : No

Functions

Localization

Domains (AlphaFold: FBXO6)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878FBXO6ENSG00000116663.106.6312.499.56ENCSR000AEF
HepG2FBXO6ENSG00000116663.104.243.373.81ENCSR985KAT
K562FBXO6ENSG00000116663.1024.6523.3123.98ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for FBXO6 is not avaliable on ENCORE database.



Proteins bound to RNA
  • FBXO6 RNA is bound by 3 proteins.  







eCLIP assay for FBXO6 is not avaliable on ENCORE database.





3 proteins are bound to FBXO6 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr11173406911734115+3'-UTR,polyA_site4.671145.24231K562UPF1
chr11173333511733432+CDS4.5617813.47097K562YBX3
chr11172871911728770+CDS4.714956.47760K562YBX3
chr11173368311733709+CDS4.672896.69007K562YBX3
chr11172890511729001+CDS3.471834.22563K562UCHL5
chr11173370911733737+CDS6.1365022.88828K562YBX3
chr11173373711733775+CDS5.9746319.53667K562YBX3
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for FBXO6 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for FBXO6 is not available on ENCORE database.

  • 88 RBPs can affect the levels of FBXO6.  








The Knockdown/knockout RNA-Seq assay for FBXO6 is not available on ENCORE database.





88 RBPs can affect the gene expression of FBXO6 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
FBXO6ENSG00000116663.6189.6365097.026800.966703.803602.70830HepG2ABCF1
FBXO6ENSG00000116663.6128.7540068.385000.912802.462401.61500HepG2BCLAF1
FBXO6ENSG00000116663.6378.72530132.970501.5099015.1152013.47380HepG2CIRBP
FBXO6ENSG00000116663.6134.6251093.602300.524202.090001.43270HepG2DAZAP1
FBXO6ENSG00000116663.6158.9648055.055501.529608.698107.56510HepG2DDX21
FBXO6ENSG00000116663.6124.5681063.028500.982803.747802.58000HepG2DDX5
FBXO6ENSG00000116663.6243.4819077.601501.6496015.1737013.85500HepG2DKC1
FBXO6ENSG00000116663.688.9985049.569100.844202.765702.11430HepG2DNAJC2
FBXO6ENSG00000116663.6142.4800056.306001.339305.428304.17410HepG2EEF2
FBXO6ENSG00000116663.6100.0261052.073100.941703.146901.99930HepG2EIF3G
FBXO6ENSG00000116663.6302.58570147.876401.032906.710305.71220HepG2EIF4A3
FBXO6ENSG00000116663.646.26550143.97450-1.637806.915205.85870HepG2EIF4B
FBXO6ENSG00000116663.6139.6269084.055900.732102.429901.40450HepG2ESF1
FBXO6ENSG00000116663.652.57200138.40340-1.396506.505205.50840HepG2G3BP1
FBXO6ENSG00000116663.6224.79030146.928700.613402.547801.69530HepG2G3BP2
FBXO6ENSG00000116663.6217.2191063.132801.7826011.6247010.38940HepG2GPKOW
FBXO6ENSG00000116663.6195.9530050.499701.9561013.8314012.56120HepG2HNRNPA1
FBXO6ENSG00000116663.6157.6601056.168301.488907.458806.36510HepG2HNRNPC
FBXO6ENSG00000116663.641.62120140.13840-1.751508.586907.40900HepG2HNRNPK
FBXO6ENSG00000116663.6134.5348060.248101.158904.660703.86490HepG2HNRNPLL
FBXO6ENSG00000116663.695.8874055.797200.781002.388001.82160HepG2HNRNPU
FBXO6ENSG00000116663.6156.3719072.689101.105106.095005.06110HepG2IGF2BP1
FBXO6ENSG00000116663.647.98410132.02230-1.460203.447402.34930HepG2IGF2BP3
FBXO6ENSG00000116663.6152.3319089.790600.762502.261201.51800HepG2LARP4
FBXO6ENSG00000116663.6253.54420149.247000.764403.871003.09610HepG2MAGOH
FBXO6ENSG00000116663.690.29000150.08330-0.733102.318301.73740HepG2MATR3
FBXO6ENSG00000116663.6142.7709053.415501.418306.559805.43270HepG2NSUN2
FBXO6ENSG00000116663.675.26100175.08820-1.218107.489206.56920HepG2PCBP1
FBXO6ENSG00000116663.6404.5626088.610702.1907033.1859031.40510HepG2PUF60
FBXO6ENSG00000116663.6231.0771082.617401.4838013.6041012.41640HepG2PUS1
FBXO6ENSG00000116663.6118.43110192.97150-0.704303.330802.65470HepG2QKI
FBXO6ENSG00000116663.671.66010175.11780-1.289106.850205.82960HepG2RBM25
FBXO6ENSG00000116663.6118.8563052.207501.186803.658902.43860HepG2RCC2
FBXO6ENSG00000116663.6101.51020198.26790-0.965805.527804.80550HepG2NELFE
FBXO6ENSG00000116663.6100.40850184.62920-0.878704.695203.92120HepG2RECQL
FBXO6ENSG00000116663.6135.8253079.501200.772602.857602.16470HepG2RPLP0
FBXO6ENSG00000116663.6161.5797059.291601.446207.147405.90270HepG2RPS2
FBXO6ENSG00000116663.674.1330030.310301.290203.413202.52390HepG2RPS3A
FBXO6ENSG00000116663.698.6310049.691800.988903.530702.81870HepG2SAFB2
FBXO6ENSG00000116663.6101.9811059.638500.773902.167801.53820HepG2SF3B1
FBXO6ENSG00000116663.6124.40390185.50140-0.576402.470601.90740HepG2SF3B4
FBXO6ENSG00000116663.6139.7362084.983800.717303.160602.41830HepG2SLBP
FBXO6ENSG00000116663.667.24900157.49820-1.227807.517706.68930HepG2SRSF9
FBXO6ENSG00000116663.6436.6991090.433902.2716042.6084041.17620HepG2SSB
FBXO6ENSG00000116663.6156.7308077.043901.024403.135902.42020HepG2SUPV3L1
FBXO6ENSG00000116663.659.66750173.98200-1.5439010.392209.41590HepG2TAF15
FBXO6ENSG00000116663.6108.1400058.701300.881302.719802.00090HepG2TARDBP
FBXO6ENSG00000116663.6158.1713060.343501.390103.078801.95620HepG2TBRG4
FBXO6ENSG00000116663.673.32560159.90920-1.124905.594104.41870HepG2TIA1
FBXO6ENSG00000116663.6185.1873054.229801.7717013.2539012.29830HepG2TIAL1
FBXO6ENSG00000116663.616.3747045.50300-1.474503.241402.42080HepG2UCHL5
FBXO6ENSG00000116663.6121.0001080.388200.589901.901501.30420HepG2UPF1
FBXO6ENSG00000116663.6190.2468075.841701.326705.867904.82410HepG2XRN2
FBXO6ENSG00000116663.6156.5806088.412600.824504.095003.46530HepG2ZNF622
FBXO6ENSG00000116663.6272.54510429.18600-0.655104.542502.98660K562AARS
FBXO6ENSG00000116663.61055.97610613.066900.7844015.5004014.26970K562AGGF1
FBXO6ENSG00000116663.6934.94960673.735800.472602.244601.37080K562AKAP8
FBXO6ENSG00000116663.61063.19800637.940600.736804.132303.33150K562AKAP8L
FBXO6ENSG00000116663.6474.20170641.25600-0.435403.150101.82290K562APOBEC3C
FBXO6ENSG00000116663.6929.29050669.384900.473203.984802.87040K562ATP5C1
FBXO6ENSG00000116663.6514.58540361.884200.507804.259803.05120K562BCLAF1
FBXO6ENSG00000116663.6360.89250250.635300.525903.179102.33740K562CPSF6
FBXO6ENSG00000116663.6382.77030274.543100.479302.687501.64570K562CSTF2
FBXO6ENSG00000116663.6677.15660486.347000.477403.626502.41540K562DDX3X
FBXO6ENSG00000116663.6381.03750525.19430-0.462903.350702.64400K562DDX47
FBXO6ENSG00000116663.6826.85140686.365100.268602.111701.35790K562DKC1
FBXO6ENSG00000116663.6680.09610534.200600.348302.986701.72240K562EIF2S1
FBXO6ENSG00000116663.6226.96330356.03000-0.649502.760901.76000K562EIF3A
FBXO6ENSG00000116663.6603.93320443.525100.445303.247301.82610K562EWSR1
FBXO6ENSG00000116663.6293.56290407.87160-0.474402.467001.41230K562FKBP4
FBXO6ENSG00000116663.6287.75940528.41130-0.8768010.514709.42130K562FXR1
FBXO6ENSG00000116663.663.23530189.59700-1.584104.721603.74150K562G3BP2
FBXO6ENSG00000116663.6336.38540239.292500.491202.506101.74740K562GPKOW
FBXO6ENSG00000116663.6862.98950533.531400.693707.142905.91790K562GRSF1
FBXO6ENSG00000116663.6633.49840400.097700.662902.561501.40230K562HNRNPA2B1
FBXO6ENSG00000116663.6207.94450469.38000-1.1746013.0385011.81880K562HNRNPC
FBXO6ENSG00000116663.6645.82980336.505900.9404010.047608.56030K562HSPD1
FBXO6ENSG00000116663.6502.28450331.371000.600002.638101.64410K562IGF2BP2
FBXO6ENSG00000116663.6475.75820336.920600.497703.107301.82850K562IGF2BP3
FBXO6ENSG00000116663.6908.75090676.955900.424703.903102.90110K562KIF1C
FBXO6ENSG00000116663.6856.12890648.060900.401603.136101.97260K562MAK16
FBXO6ENSG00000116663.6477.27300303.000000.655404.183702.51390K562NONO
FBXO6ENSG00000116663.6702.98500349.955301.006205.252903.76670K562PABPN1
FBXO6ENSG00000116663.6534.98270281.778400.924809.490707.72270K562PPIG
FBXO6ENSG00000116663.6789.69710416.041200.924504.253302.30510K562PPP1R8
FBXO6ENSG00000116663.61022.74520632.542700.693105.128904.41800K562PUS1
FBXO6ENSG00000116663.61025.40340616.416500.734107.087506.16810K562RBM15
FBXO6ENSG00000116663.6615.31600387.962300.665303.460001.70760K562SBDS
FBXO6ENSG00000116663.6590.73010320.033200.884203.440502.06100K562SF1
FBXO6ENSG00000116663.6883.17000390.141901.178606.682104.30250K562SFPQ
FBXO6ENSG00000116663.6508.17820313.123800.698505.861104.22980K562SRSF5
FBXO6ENSG00000116663.6415.43720289.370900.521602.575401.59810K562SUPV3L1
FBXO6ENSG00000116663.6551.15290335.378400.716606.126105.04100K562TARDBP
FBXO6ENSG00000116663.6480.10250323.530600.569303.173702.28930K562TIA1
FBXO6ENSG00000116663.6449.21170317.661800.499802.520801.48780K562TRA2A
FBXO6ENSG00000116663.6574.68940430.199300.417702.647301.72650K562TRIM56
FBXO6ENSG00000116663.6586.63370435.467100.429803.094002.17070K562WDR3
FBXO6ENSG00000116663.6361.18510452.84880-0.326302.112501.36550K562WDR43
FBXO6ENSG00000116663.6456.59970312.031100.549102.437401.32700K562XRN2
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for FBXO6 is not available on ENCORE database.





3 RBPs can affect the splicing of FBXO6 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
MXEFBXO6ENSG00000116663.6chr1+1173132211731449117319841173208011728712117290011173333311733469-0.118000.007840.096492includedHepG2FTO
MXEFBXO6ENSG00000116663.6chr1+11731322117314491173198411732080117287121172900111733333117334690.077000.003270.041331includedK562DROSHA
MXEFBXO6ENSG00000116663.6chr1+1173132211731449117319841173208011728712117290011173333311733469-0.142000.000080.025472includedK562SDAD1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for FBXO6 is not avaliable on ENCORE database.