DNASE2

General Information

Gene Name       : DNASE2
Gene ID             : ENSG00000105612.8
Essential Gene : No

Functions

Localization

Domains (AlphaFold: DNASE2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878DNASE2ENSG00000105612.810.0414.1812.11ENCSR000AEF
HepG2DNASE2ENSG00000105612.88.405.406.90ENCSR985KAT
K562DNASE2ENSG00000105612.822.5713.6818.12ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for DNASE2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • DNASE2 RNA is bound by 5 proteins.  







eCLIP assay for DNASE2 is not avaliable on ENCORE database.





5 proteins are bound to DNASE2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr191298661512986652-3'-UTR,intron-Distal,intron-Proximal3.578933.42164K562UPF1
chr191298646712986532-3'-UTR,intron-Distal4.134145.99105K562UPF1
chr191298668712986733-3'-UTR,intron-Distal,intron-Proximal3.406953.07801K562UPF1
chr191298645612986526-3'-UTR,intron-Distal5.449167.68318K562DDX6
chr191298626212986307-3'-UTR,intron-Distal3.257173.07801K562UPF1
chr191298712012987175-CDS,intron-Distal5.8901611.47560K562SND1
chr191298960412989639-CDS,intron-Distal4.6349211.67493K562SND1
chr191299183712991886-CDS,intron-Distal5.294448.62697K562SND1
chr191298921212989259-CDS,intron-Distal4.343436.75747K562SND1
chr191298919512989203-CDS,intron-Distal,intron-Proximal4.465994.13314K562SND1
chr191298954412989604-CDS,intron-Distal,intron-Proximal3.387807.87628K562SND1
chr191298686412986922-CDS,intron-Distal4.109933.91218HepG2SND1
chr191298700812987059-CDS,intron-Distal,intron-Proximal3.422705.03659K562SND1
chr191298928512989338-CDS,intron-Distal3.617449.70336K562SND1
chr191299161512991664-CDS,intron-Distal,intron-Proximal3.636803.48584HepG2SND1
chr191298963912989648-CDS,intron-Distal4.906208.87572K562SND1
chr191299180912991850-CDS,intron-Distal3.664817.18470K562YBX3
chr191298948312989503-CDS,intron-Distal,intron-Proximal3.809874.99078K562SND1
chr191298962712989649-CDS,intron-Distal,intron-Proximal4.433923.31432HepG2SND1
chr191298950012989637-CDS,intron-Distal,intron-Proximal3.254883.74671K562IGF2BP2
chr191299161512991658-CDS,intron-Distal,intron-Proximal5.3285514.43845K562SND1
chr191298936912989393-CDS,intron-Distal,intron-Proximal3.943085.28221K562SND1
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for DNASE2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for DNASE2 is not available on ENCORE database.

  • 93 RBPs can affect the levels of DNASE2.  








The Knockdown/knockout RNA-Seq assay for DNASE2 is not available on ENCORE database.





93 RBPs can affect the gene expression of DNASE2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
DNASE2ENSG00000105612.4424.25750224.847500.9159010.833709.79520HepG2ACO1
DNASE2ENSG00000105612.41467.16660359.645102.0283040.6780038.97920HepG2AKAP1
DNASE2ENSG00000105612.4359.47120225.878400.670205.485904.44060HepG2AKAP8L
DNASE2ENSG00000105612.4124.14500183.16180-0.561102.050001.52930HepG2BOP1
DNASE2ENSG00000105612.4529.79600304.960200.796705.337103.96490HepG2CCAR1
DNASE2ENSG00000105612.469.17080131.39890-0.925703.458102.26910HepG2CSTF2
DNASE2ENSG00000105612.4443.56690339.602900.385202.856402.10400HepG2DAZAP1
DNASE2ENSG00000105612.4300.45970210.995500.509902.503401.85590HepG2DDX21
DNASE2ENSG00000105612.4945.86850344.523701.4569022.5980020.99050HepG2DDX3X
DNASE2ENSG00000105612.4851.18700295.927201.5241015.3140014.02130HepG2DDX6
DNASE2ENSG00000105612.4121.14640215.11020-0.828304.791403.94440HepG2DKC1
DNASE2ENSG00000105612.4216.58670163.416400.406301.856001.30270HepG2DNAJC2
DNASE2ENSG00000105612.4500.95910284.507600.816106.365805.48660HepG2EIF2S1
DNASE2ENSG00000105612.4306.93320206.530600.571502.847401.66010HepG2EIF2S2
DNASE2ENSG00000105612.4119.20830199.24830-0.741103.682102.45740HepG2EIF3G
DNASE2ENSG00000105612.4219.13880314.42670-0.520902.271701.69010HepG2EIF4A3
DNASE2ENSG00000105612.476.13170306.11490-2.0075015.9735014.40770HepG2EIF4B
DNASE2ENSG00000105612.4141.38920335.04930-1.2447012.8564011.31450HepG2EIF4G1
DNASE2ENSG00000105612.4208.53580138.053100.595002.812901.63360HepG2FAM120A
DNASE2ENSG00000105612.4513.19600274.996700.900006.048804.95350HepG2FIP1L1
DNASE2ENSG00000105612.4340.97270208.600900.708803.611902.33700HepG2FUS
DNASE2ENSG00000105612.4176.15640312.38460-0.826505.049603.83540HepG2G3BP2
DNASE2ENSG00000105612.4500.45920154.569101.6949017.2667014.59860HepG2GRSF1
DNASE2ENSG00000105612.4368.20550214.646400.778407.503105.99100HepG2HDGF
DNASE2ENSG00000105612.4477.76620309.348700.627006.647405.64680HepG2HNRNPL
DNASE2ENSG00000105612.4390.81520236.483600.724604.094302.58690HepG2HSPD1
DNASE2ENSG00000105612.4287.25980187.863600.612604.673903.74220HepG2ILF2
DNASE2ENSG00000105612.4195.22050322.19720-0.722803.495502.56150HepG2LARP4
DNASE2ENSG00000105612.4204.66570317.31650-0.632703.226502.51880HepG2MAGOH
DNASE2ENSG00000105612.4512.38710319.098600.683104.362603.58650HepG2MATR3
DNASE2ENSG00000105612.4637.85800326.620100.965509.201508.08660HepG2NCBP2
DNASE2ENSG00000105612.4524.14580336.750200.638206.079604.94980HepG2NOL12
DNASE2ENSG00000105612.4101.94490161.29260-0.661902.165501.50150HepG2NSUN2
DNASE2ENSG00000105612.4411.11090290.899200.498902.674001.96340HepG2PABPC4
DNASE2ENSG00000105612.4254.50600182.041900.483302.471201.66630HepG2PARN
DNASE2ENSG00000105612.4170.12100233.03600-0.454002.077801.39910HepG2PRPF4
DNASE2ENSG00000105612.4188.65340299.75560-0.668004.578703.91400HepG2PTBP1
DNASE2ENSG00000105612.4461.82880340.997000.437502.835402.15720HepG2PUM2
DNASE2ENSG00000105612.4156.41140229.01730-0.550102.952302.32130HepG2PUS1
DNASE2ENSG00000105612.4201.62380324.68370-0.687404.657103.87800HepG2QKI
DNASE2ENSG00000105612.4418.62030259.123500.691905.832604.64490HepG2RBM15
DNASE2ENSG00000105612.4682.80870390.270100.8069010.525109.65800HepG2RBM22
DNASE2ENSG00000105612.4114.62700189.13500-0.722502.731801.67950HepG2RCC2
DNASE2ENSG00000105612.4226.95170333.61520-0.555803.567502.96920HepG2NELFE
DNASE2ENSG00000105612.482.54690159.60470-0.951203.561002.68420HepG2RRP9
DNASE2ENSG00000105612.4106.54080180.04090-0.756903.081702.33770HepG2SF3B1
DNASE2ENSG00000105612.4253.58590190.996700.408802.020301.45730HepG2SMN1
DNASE2ENSG00000105612.4285.22970194.619900.551402.412701.52220HepG2SMNDC1
DNASE2ENSG00000105612.4210.07970276.76740-0.397701.943701.34910HepG2SRSF7
DNASE2ENSG00000105612.4102.04230382.70290-1.9071029.9331028.65460HepG2SSB
DNASE2ENSG00000105612.4116.32400208.20670-0.839903.497802.74890HepG2SUPV3L1
DNASE2ENSG00000105612.4536.10920292.776000.8726010.266009.29480HepG2TAF15
DNASE2ENSG00000105612.4414.90280177.310701.2264012.1673010.81070HepG2TARDBP
DNASE2ENSG00000105612.4319.37540180.307000.824707.280106.44120HepG2TRIM56
DNASE2ENSG00000105612.4296.12790198.942200.573803.583002.40720HepG2UTP18
DNASE2ENSG00000105612.4125.62810186.86330-0.572802.168301.62460HepG2UTP3
DNASE2ENSG00000105612.4116.29220204.95660-0.817603.427002.62480HepG2XRN2
DNASE2ENSG00000105612.4117.57140229.96450-0.967906.904405.92150HepG2ZC3H8
DNASE2ENSG00000105612.41729.832501337.061600.371505.785305.01240K562AGGF1
DNASE2ENSG00000105612.4927.13440704.249800.396604.286402.36810K562AKAP1
DNASE2ENSG00000105612.42190.094901469.327900.575708.093706.16970K562AKAP8
DNASE2ENSG00000105612.41903.651001391.297700.452205.138304.23610K562AKAP8L
DNASE2ENSG00000105612.4504.87940743.42100-0.558202.649901.43780K562APOBEC3C
DNASE2ENSG00000105612.4596.74600275.717201.1138012.0799010.21530K562BOP1
DNASE2ENSG00000105612.4651.49020293.151501.1520016.4058014.46410K562CPSF6
DNASE2ENSG00000105612.4430.80860291.027700.565804.237502.89180K562CSTF2
DNASE2ENSG00000105612.4711.09220551.704400.366003.175201.87150K562DDX21
DNASE2ENSG00000105612.4910.92410713.599300.352102.838701.78260K562DDX3X
DNASE2ENSG00000105612.4420.08640644.28040-0.617007.177806.19680K562DDX47
DNASE2ENSG00000105612.41034.96620723.500000.516405.350003.31090K562DDX6
DNASE2ENSG00000105612.41164.49700389.465301.5800047.6275045.39990K562EIF2S2
DNASE2ENSG00000105612.4133.78140303.99790-1.184205.989104.47570K562EIF3A
DNASE2ENSG00000105612.4229.61500455.49050-0.988209.733208.23870K562EIF3G
DNASE2ENSG00000105612.4533.73300298.303800.839207.454406.01610K562FMR1
DNASE2ENSG00000105612.4400.48220252.852000.663304.288703.12800K562FTO
DNASE2ENSG00000105612.4281.48620775.33420-1.4618032.2566030.32210K562FXR1
DNASE2ENSG00000105612.4329.51410473.16510-0.522002.685801.99170K562G3BP2
DNASE2ENSG00000105612.4587.68560279.875501.0702012.5470010.83930K562GPKOW
DNASE2ENSG00000105612.41004.87500518.878100.953409.828608.37950K562GRSF1
DNASE2ENSG00000105612.4836.65350409.478201.0307013.6125011.89760K562HSPD1
DNASE2ENSG00000105612.41030.77830757.425500.444502.818801.78180K562IGF2BP2
DNASE2ENSG00000105612.4968.77460770.212500.330802.387101.30330K562IGF2BP3
DNASE2ENSG00000105612.41823.917501476.429000.304803.191602.30020K562KIF1C
DNASE2ENSG00000105612.4402.47660239.010300.751704.059202.90980K562KRR1
DNASE2ENSG00000105612.4556.14240795.54980-0.516503.745202.75800K562MAGOH
DNASE2ENSG00000105612.41880.881901413.375200.412203.999702.63310K562MAK16
DNASE2ENSG00000105612.4539.39880793.86370-0.557504.953703.67850K562MATR3
DNASE2ENSG00000105612.42299.892601653.985300.475504.303803.12440K562MBNL1
DNASE2ENSG00000105612.4384.95380273.194800.494702.721201.85340K562METAP2
DNASE2ENSG00000105612.4663.30550535.686100.308202.395301.64210K562MTPAP
DNASE2ENSG00000105612.4931.76690744.458900.323702.541701.36600K562NCBP2
DNASE2ENSG00000105612.4559.89170338.332100.726605.369003.41940K562NONO
DNASE2ENSG00000105612.4827.15190595.163600.474806.358905.29000K562NSUN2
DNASE2ENSG00000105612.4781.63220499.871100.644805.255202.77060K562PABPC4
DNASE2ENSG00000105612.4481.64050707.75570-0.555304.664103.38700K562PCBP2
DNASE2ENSG00000105612.4482.73450342.873300.493503.092402.21700K562PPIG
DNASE2ENSG00000105612.4505.35110772.96190-0.613105.434504.53120K562PTBP1
DNASE2ENSG00000105612.41845.416101379.611000.419604.147003.50180K562PUS1
DNASE2ENSG00000105612.41820.920201344.367700.437605.476104.66660K562RBM15
DNASE2ENSG00000105612.4531.01080740.91890-0.480603.861902.85750K562RBM22
DNASE2ENSG00000105612.4585.92060779.75920-0.412302.326001.34260K562NELFE
DNASE2ENSG00000105612.4496.30640825.03200-0.733204.378003.08000K562RPS3
DNASE2ENSG00000105612.4278.45510377.13270-0.437602.299501.31730K562SAFB
DNASE2ENSG00000105612.4272.89200389.88030-0.514702.921901.43130K562SDAD1
DNASE2ENSG00000105612.41338.18690808.724100.726502.850601.62240K562SF1
DNASE2ENSG00000105612.4941.05110587.321800.6800010.413608.90650K562SF3A3
DNASE2ENSG00000105612.4481.31010601.72810-0.322102.375701.50030K562SRPK2
DNASE2ENSG00000105612.41093.38380715.829800.611006.584404.85320K562SRSF5
DNASE2ENSG00000105612.4634.11730492.278600.365203.139001.88550K562SRSF7
DNASE2ENSG00000105612.4769.43630469.831300.711608.768506.39400K562SSB
DNASE2ENSG00000105612.4245.65200424.49050-0.789107.094305.76310K562SYNCRIP
DNASE2ENSG00000105612.41056.18340739.735900.513702.945202.09730K562TIA1
DNASE2ENSG00000105612.4361.24550473.49960-0.390402.522101.75540K562U2AF2
DNASE2ENSG00000105612.4491.17980342.012200.522102.976401.91220K562UCHL5
DNASE2ENSG00000105612.41009.75690631.067100.678007.870906.73280K562UPF1
DNASE2ENSG00000105612.4633.98120450.975800.491303.219001.91760K562UTP3
DNASE2ENSG00000105612.4793.64150539.980100.555505.531704.27340K562WDR3
DNASE2ENSG00000105612.4380.05690561.54480-0.563206.041604.84150K562WDR43
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for DNASE2 is not available on ENCORE database.






No RBPs affect the alternative splcing events of DNASE2 on ENCORE database.





The Knockdown/knockout RNA-Seq assay for DNASE2 is not avaliable on ENCORE database.