DENR

General Information

Gene Name       : DENR
Gene ID             : ENSG00000139726.10
Essential Gene : No

Functions

Localization

Domains (AlphaFold: DENR)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878DENRENSG00000139726.1047.1246.1446.63ENCSR000AEF
HepG2DENRENSG00000139726.1021.5547.2034.38ENCSR985KAT
K562DENRENSG00000139726.1053.0652.0952.58ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  
  GeneName    Cell_Line    Method    Exp_ID    Control_ID    Sample_reps    Control_reps    KD%    Status    Project    Note  
DENRK562CRISPRBGKcLV37-17,BGKcLV37-18BGKcLV37-1,BGKcLV37-20.0,0.0NotSatisfiedENCORE2
DENRK562CRISPRBGKcLV44-17,BGKcLV44-18BGKcLV44-1,BGKcLV44-20.0,0.0NotSatisfiedENCORE2
DENRK562CRISPRBGKcLV46-13,BGKcLV46-14BGKcLV46-1,BGKcLV46-240.9,38.0ExperimentedENCORE2
DENRK562CRISPRBGKcLV46-15,BGKcLV46-16BGKcLV46-1,BGKcLV46-250.8,51.8ExperimentedENCORE2
DENRHepG2CRISPRBGHcLV41-5,BGHcLV41-6BGHcLV41-1,BGHcLV41-20.0,0.0NotSatisfiedENCORE2
DENRHepG2CRISPRBGHcLV45-21,BGHcLV45-22BGHcLV45-1,BGHcLV45-20.0,0.0NotSatisfiedENCORE2


  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for DENR is not avaliable on ENCORE database.



Proteins bound to RNA
  • DENR RNA is bound by 17 proteins.  







eCLIP assay for DENR is not avaliable on ENCORE database.





17 proteins are bound to DENR RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr12123253891123253930+3'-UTR,intron-Distal4.3340311.65401K562UPF1
chr12123254467123254628+3'-UTR3.7541129.33267K562FAM120A
chr12123254431123254449+3'-UTR4.286456.14808K562UPF1
chr12123254404123254415+3'-UTR4.8542118.29285K562UPF1
chr12123254609123254655+3'-UTR4.3357014.24877K562UPF1
chr12123255189123255235+3'-UTR3.748579.72135K562FAM120A
chr12123255050123255123+3'-UTR4.2313313.80116K562FAM120A
chr12123254464123254531+3'-UTR4.788266.81418HepG2UPF1
chr12123254399123254403+3'-UTR5.1265115.12816K562UPF1
chr12123254468123254609+3'-UTR3.9534239.64969K562UPF1
chr12123254415123254431+3'-UTR4.8665418.29285K562UPF1
chr12123254908123255019+3'-UTR3.2711316.58429K562FAM120A
chr12123254067123254115+3'-UTR,intron-Distal,intron-Proximal3.153078.54752K562FAM120A
chr12123255178123255213+3'-UTR3.088485.00311K562UPF1
chr12123255245123255267+3'-UTR3.002644.79181K562FAM120A
chr12123254736123254744+3'-UTR4.180705.99105K562UPF1
chr12123254830123254870+3'-UTR3.211668.47743K562UPF1
chr12123254538123254600+3'-UTR3.7584214.04573HepG2SUB1
chr12123255418123255536+3'-UTR4.7456210.78284K562TARDBP
chr12123254385123254399+3'-UTR4.9486413.37062K562UPF1
chr12123254063123254117+3'-UTR,intron-Distal,intron-Proximal3.921245.87389HepG2UPF1
chr12123237374123237451+5'-UTR4.886536.15796HepG2DDX3X
chr12123237392123237500+5'-UTR,intron-Proximal4.0857117.28467K562DDX3X
chr12123237451123237498+5'-UTR,intron-Proximal4.127464.38588HepG2DDX3X
chr12123238238123238314+5'-UTR,CDS,intron-Proximal3.8232219.41525K562DDX3X
chr12123238343123238459+CDS,intron-Distal,intron-Proximal3.007034.81794K562KHSRP
chr12123252052123252148+CDS5.602549.32793HepG2BCLAF1
chr12123252032123252134+CDS,intron-Proximal3.089214.83973K562ZNF622
chr12123249844123249901+CDS,intron-Proximal4.700713.39588K562SF3B4
chr12123249878123249935+CDS,intron-Proximal3.165074.86973K562UCHL5
chr12123246719123246768+CDS,intron-Proximal3.162934.43994HepG2U2AF2
chr12123249851123249974+CDS,intron-Proximal3.013144.61019K562GPKOW
chr12123238324123238392+CDS,intron-Proximal5.607706.35567HepG2PRPF8
chr12123249852123249935+CDS,intron-Proximal3.149096.50801HepG2BCLAF1
chr12123249871123249935+CDS,intron-Proximal4.372623.77023K562ZNF622
chr12123246667123246742+CDS,intron-Proximal3.504974.57435K562SF3B4
chr12123247343123247537+CDS,intron-Proximal3.408235.37841K562SF3B4
chr12123251730123251811+intron-Distal3.077093.31830K562KHSRP
chr12123252704123252730+intron-Distal3.644175.29248K562TROVE2
chr12123251246123251322+intron-Distal4.3748211.16945K562PTBP1
chr12123243205123243264+intron-Distal3.711883.38675HepG2ILF3
chr12123252730123252754+intron-Distal3.451534.87403K562TROVE2
chr12123243407123243462+intron-Distal3.517605.11500HepG2ILF3
chr12123238662123238723+intron-Distal4.200453.43967HepG2TAF15
chr12123251261123251322+intron-Distal5.246328.13723HepG2PTBP1
chr12123251564123251647+intron-Distal3.697433.89405HepG2PTBP1
chr12123249798123249844+intron-Proximal4.776724.40745K562SF3B4
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for DENR is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for DENR is not available on ENCORE database.

  • 86 RBPs can affect the levels of DENR.  








The Knockdown/knockout RNA-Seq assay for DENR is not available on ENCORE database.





86 RBPs can affect the gene expression of DENR :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
DENRENSG00000139726.61042.947802023.42500-0.9561012.2055010.64800HepG2ASCC1
DENRENSG00000139726.61116.777601525.37330-0.449802.601301.69450HepG2BCCIP
DENRENSG00000139726.61512.846602007.64530-0.408203.937703.23670HepG2BOP1
DENRENSG00000139726.61463.724102180.57220-0.575103.146402.10250HepG2CCAR1
DENRENSG00000139726.61325.462801595.19480-0.267202.468601.83330HepG2CKAP4
DENRENSG00000139726.61405.57730998.825900.492802.179701.50550HepG2CNOT7
DENRENSG00000139726.61257.358501843.14240-0.551806.022805.04370HepG2CPSF6
DENRENSG00000139726.61865.203302130.74520-0.192002.548301.83140HepG2DAZAP1
DENRENSG00000139726.6922.536101125.59980-0.287001.970301.38510HepG2DDX21
DENRENSG00000139726.61462.572402012.10670-0.460203.470402.78570HepG2DDX6
DENRENSG00000139726.6769.038401108.21490-0.527109.516608.39370HepG2DNAJC2
DENRENSG00000139726.61134.125401934.54680-0.770409.686108.61720HepG2EIF2S1
DENRENSG00000139726.61479.174702138.02740-0.531504.460903.65240HepG2EIF4A3
DENRENSG00000139726.61623.531402081.42980-0.358401.900201.32270HepG2EIF4B
DENRENSG00000139726.62509.218002101.963300.255403.060602.18830HepG2EIF4G1
DENRENSG00000139726.61690.487302156.79960-0.351502.582101.91420HepG2FXR1
DENRENSG00000139726.61422.228402000.94800-0.492504.151903.34640HepG2G3BP1
DENRENSG00000139726.6542.18690775.30510-0.516002.872801.95710HepG2GEMIN5
DENRENSG00000139726.61424.184802089.38550-0.552905.138704.28410HepG2GPKOW
DENRENSG00000139726.6793.544801255.66060-0.662107.965406.83530HepG2HNRNPC
DENRENSG00000139726.61326.261401722.59790-0.377204.009303.16200HepG2HNRNPF
DENRENSG00000139726.61637.976301940.99780-0.244903.674002.90510HepG2HNRNPL
DENRENSG00000139726.6770.198101993.93550-1.3723029.2952027.60140HepG2HNRNPLL
DENRENSG00000139726.6818.295001247.34930-0.608206.013204.67980HepG2HNRNPM
DENRENSG00000139726.61464.668302033.99110-0.473704.189403.37410HepG2IGF2BP2
DENRENSG00000139726.61095.111501274.14410-0.218502.276601.60340HepG2ILF2
DENRENSG00000139726.61230.534002045.71440-0.733306.745705.10530HepG2KHSRP
DENRENSG00000139726.61193.139801458.45780-0.289703.108802.03000HepG2KIF1C
DENRENSG00000139726.61461.030502157.55090-0.562405.606004.68300HepG2MAGOH
DENRENSG00000139726.61784.988802220.84690-0.315202.021001.47530HepG2NCBP2
DENRENSG00000139726.61654.022902112.83340-0.353204.452103.48610HepG2NOL12
DENRENSG00000139726.61365.040001978.04010-0.535105.041004.07730HepG2PABPC4
DENRENSG00000139726.61199.661601867.00590-0.6381014.8788013.65310HepG2PCBP1
DENRENSG00000139726.6909.567501112.55260-0.290602.643401.92130HepG2PPIL4
DENRENSG00000139726.61488.572201899.71650-0.351904.653503.98490HepG2PTBP1
DENRENSG00000139726.61444.664902016.83680-0.481405.953105.12210HepG2PUF60
DENRENSG00000139726.61568.951702139.37640-0.447406.268805.27350HepG2PUM2
DENRENSG00000139726.61277.192801624.96180-0.347404.293903.55750HepG2PUS1
DENRENSG00000139726.61604.838702057.50770-0.358504.426903.66300HepG2QKI
DENRENSG00000139726.61324.952101867.29480-0.495006.289605.31010HepG2RBM25
DENRENSG00000139726.61608.134502114.22850-0.394706.344905.58160HepG2NELFE
DENRENSG00000139726.61546.956801969.06860-0.348105.201204.39080HepG2RECQL
DENRENSG00000139726.6812.447601110.85030-0.451306.037705.14150HepG2SAFB2
DENRENSG00000139726.61682.414601977.90710-0.233402.623902.04520HepG2SF3B4
DENRENSG00000139726.61313.032801933.71750-0.5585014.2354012.86190HepG2SLBP
DENRENSG00000139726.6801.269601341.73960-0.743706.318704.82490HepG2SMNDC1
DENRENSG00000139726.62394.409702064.483500.213802.433601.98270HepG2SRSF1
DENRENSG00000139726.61554.064801991.26570-0.357605.672904.82300HepG2SRSF5
DENRENSG00000139726.61347.256501692.33600-0.329003.892803.08780HepG2SRSF7
DENRENSG00000139726.62041.520902325.96130-0.188202.142801.67680HepG2SSB
DENRENSG00000139726.61996.911002264.67490-0.181502.277001.70250HepG2SUCLG1
DENRENSG00000139726.6401.350201493.02770-1.8953030.8604029.05850HepG2SUPV3L1
DENRENSG00000139726.61290.849001943.36360-0.590207.137406.04840HepG2TARDBP
DENRENSG00000139726.61263.173001705.08800-0.432805.030803.91410HepG2TIA1
DENRENSG00000139726.6897.168401212.17060-0.434104.873004.24800HepG2TIAL1
DENRENSG00000139726.6961.116701222.87130-0.347504.328303.65430HepG2TRIM56
DENRENSG00000139726.61642.030301970.27300-0.262902.271801.48550HepG2TUFM
DENRENSG00000139726.62070.369501546.403700.420903.986303.23830HepG2U2AF1
DENRENSG00000139726.6346.80520882.05330-1.3467017.3769015.50470HepG2UCHL5
DENRENSG00000139726.61251.320501444.97400-0.207602.059701.52750HepG2UTP3
DENRENSG00000139726.61088.758301469.71860-0.432902.804602.07560HepG2XRN2
DENRENSG00000139726.61958.019801646.048300.250303.725903.11640HepG2ZNF622
DENRENSG00000139726.61956.241002443.31100-0.320802.349701.74640K562AKAP8L
DENRENSG00000139726.62751.891403589.62320-0.383404.004903.32410K562AQR
DENRENSG00000139726.61672.911101936.48030-0.211102.178501.32440K562BCLAF1
DENRENSG00000139726.62358.173702888.67750-0.292703.907802.58510K562CPEB4
DENRENSG00000139726.61604.996402251.95280-0.488605.817704.68820K562CPSF6
DENRENSG00000139726.64524.240802989.127100.5979018.0711016.53660K562DDX47
DENRENSG00000139726.61196.99520750.580800.673204.143002.88710K562EIF3A
DENRENSG00000139726.6907.193701459.62250-0.686109.348907.83690K562EIF4A3
DENRENSG00000139726.61018.137501314.43150-0.368504.051302.60490K562EIF4B
DENRENSG00000139726.6969.152801274.07670-0.394704.029402.42280K562EWSR1
DENRENSG00000139726.61790.132902291.19350-0.356003.042402.14250K562FMR1
DENRENSG00000139726.62091.886301517.939200.462607.672206.73200K562FXR1
DENRENSG00000139726.61606.833602150.10820-0.420204.473703.47000K562GPKOW
DENRENSG00000139726.6975.780301490.24580-0.610904.569603.82060K562HNRNPC
DENRENSG00000139726.64434.479203172.693200.483005.703604.57660K562HSPD1
DENRENSG00000139726.61687.844102171.24110-0.363302.341101.41970K562IGF2BP2
DENRENSG00000139726.61720.048502098.72550-0.287102.353501.54900K562METAP2
DENRENSG00000139726.61644.798802230.95260-0.439705.627203.63050K562PCBP1
DENRENSG00000139726.61932.087101543.415800.323902.636601.90430K562PRPF8
DENRENSG00000139726.6852.597501336.08040-0.648104.430203.24380K562PSIP1
DENRENSG00000139726.65396.010904562.195000.242102.514501.50030K562PUM1
DENRENSG00000139726.61913.961202361.01980-0.302802.228301.68670K562RBM15
DENRENSG00000139726.61652.108402126.98410-0.364502.552201.74870K562RBM22
DENRENSG00000139726.62418.174201572.356400.620906.731505.44550K562RPS19
DENRENSG00000139726.61571.288601142.749300.459303.938402.71620K562RPS3
DENRENSG00000139726.61330.631101676.84560-0.333602.190501.43080K562SF3B4
DENRENSG00000139726.6760.981801155.24980-0.602304.860303.38550K562SRFBP1
DENRENSG00000139726.61980.255802277.08170-0.201502.482601.59050K562SRPK2
DENRENSG00000139726.61580.603202052.97440-0.377203.433202.24190K562SRSF5
DENRENSG00000139726.61887.143403002.90160-0.670203.173201.41930K562STIP1
DENRENSG00000139726.6608.088401494.74210-1.2975014.7286012.37550K562SUPV3L1
DENRENSG00000139726.62060.221401533.998800.425405.468204.30630K562SYNCRIP
DENRENSG00000139726.61350.080802200.45070-0.704809.702308.24920K562TARDBP
DENRENSG00000139726.61578.642402122.53140-0.427105.220704.04590K562TIA1
DENRENSG00000139726.61571.085302082.36720-0.406504.019302.66250K562TRA2A
DENRENSG00000139726.6908.052301364.85200-0.587904.637903.34110K562TRIM56
DENRENSG00000139726.6751.015001581.80930-1.0747012.2317010.03760K562UCHL5
DENRENSG00000139726.61689.960202043.52800-0.274102.352401.54420K562WDR3
DENRENSG00000139726.62729.874302125.072500.361207.342706.02670K562WDR43
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for DENR is not available on ENCORE database.





5 RBPs can affect the splicing of DENR :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEDENRENSG00000139726.6chr12+123246733123246753123238239123238354123247391123247476-0.116000.000000.00004excludedK562SF3B4
SEDENRENSG00000139726.6chr12+123253298123253468123252034123252151123253580123255611-0.087000.000400.00646excludedHepG2U2AF2
SEDENRENSG00000139726.6chr12+123246733123246753123238239123238354123247391123247476-0.415000.000000.00000excludedHepG2U2AF2
SEDENRENSG00000139726.6chr12+123246733123246753123238239123238354123247391123247476-0.061000.000000.00000excludedK562AQR
SEDENRENSG00000139726.6chr12+123253298123253468123252009123252151123253580123255611-0.066000.000000.00000excludedK562AQR
SEDENRENSG00000139726.6chr12+123253328123253468123252034123252151123253580123255611-0.103000.000000.00000excludedHepG2SRSF1
SEDENRENSG00000139726.6chr12+123246733123246753123238239123238354123247391123247476-0.055000.003370.05310excludedK562U2AF2
SEDENRENSG00000139726.6chr12+123246733123246753123238239123238354123247391123247476-0.087000.000000.00004excludedK562TARDBP
A5SSDENRENSG00000139726.6chr12+123238239123238427123238239123238354123247391123247476-0.459000.003760.05718shorterK562AQR
MXEDENRENSG00000139726.6chr12+1232520091232521511232533281232534681232498501232499341232535801232556110.058000.000000.000001includedK562AQR
MXEDENRENSG00000139726.6chr12+1232473911232474761232498501232499341232382391232383541232520341232521510.097000.000000.000001includedK562TARDBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for DENR is not avaliable on ENCORE database.