COMMD6

General Information

Gene Name       : COMMD6
Gene ID             : ENSG00000188243.12
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: COMMD6)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878COMMD6ENSG00000188243.12100.0398.4999.26ENCSR000AEF
HepG2COMMD6ENSG00000188243.1257.6272.7565.19ENCSR985KAT
K562COMMD6ENSG00000188243.1232.1832.6332.41ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for COMMD6 is not avaliable on ENCORE database.



Proteins bound to RNA
  • COMMD6 RNA is bound by 7 proteins.  







eCLIP assay for COMMD6 is not avaliable on ENCORE database.





7 proteins are bound to COMMD6 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr137610064976100757-3'-UTR,CDS,intron-Distal3.771965.75263HepG2LARP4
chr137610424876104351-3'-UTR,CDS,intron-Distal,intron-Proximal6.0574712.44248HepG2SUB1
chr137611189976111979-5'-UTR,CDS,intron-Distal,intron-Proximal4.326104.54534K562IGF2BP2
chr137611189976111979-5'-UTR,CDS,intron-Distal,intron-Proximal4.197424.69091K562DDX3X
chr137610435176104403-CDS,intron-Distal,intron-Proximal5.9862412.79385K562PUM2
chr137610195576102011-CDS,intron-Distal,intron-Proximal4.434624.80665HepG2QKI
chr137610952376109637-intron-Distal3.176094.67779HepG2SUGP2
chr137610939576109464-intron-Distal3.123653.46325HepG2SUGP2
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for COMMD6 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for COMMD6 is not available on ENCORE database.

  • 90 RBPs can affect the levels of COMMD6.  








The Knockdown/knockout RNA-Seq assay for COMMD6 is not available on ENCORE database.





90 RBPs can affect the gene expression of COMMD6 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
COMMD6ENSG00000188243.8229.80840354.40740-0.625004.694603.71640HepG2AKAP8L
COMMD6ENSG00000188243.8459.69830315.687200.542103.977503.07660HepG2CALR
COMMD6ENSG00000188243.8721.75870533.768800.435202.218501.35410HepG2CCAR1
COMMD6ENSG00000188243.81252.52940919.621400.445603.572702.70230HepG2CIRBP
COMMD6ENSG00000188243.8484.77460352.658200.458903.959903.19140HepG2CKAP4
COMMD6ENSG00000188243.8361.65070534.61800-0.563902.590201.85130HepG2CNOT7
COMMD6ENSG00000188243.8326.03070201.274200.695702.311001.67480HepG2CPSF6
COMMD6ENSG00000188243.8421.19300258.090200.706505.280403.86010HepG2CSTF2
COMMD6ENSG00000188243.8796.42370603.428300.400303.890803.15150HepG2CELF1
COMMD6ENSG00000188243.8431.28600326.270400.402502.936502.07920HepG2DDX19B
COMMD6ENSG00000188243.8205.80070284.90160-0.469202.413301.33270HepG2DDX1
COMMD6ENSG00000188243.8593.75820358.701500.727006.669305.66590HepG2DDX21
COMMD6ENSG00000188243.8519.89080351.083900.566304.398503.23630HepG2DDX24
COMMD6ENSG00000188243.8712.109601120.65580-0.654206.093805.20030HepG2DDX3X
COMMD6ENSG00000188243.8639.93990962.56320-0.588904.393903.62960HepG2DDX6
COMMD6ENSG00000188243.8563.49950337.533500.739308.500707.44330HepG2DKC1
COMMD6ENSG00000188243.8496.99940925.43790-0.896909.947508.86460HepG2EIF2S1
COMMD6ENSG00000188243.8511.601101022.76720-0.9994011.3764010.10910HepG2EIF4A3
COMMD6ENSG00000188243.8782.41780640.114000.289502.301901.52650HepG2EIF4G1
COMMD6ENSG00000188243.8597.95390841.95680-0.493705.617504.81080HepG2ETF1
COMMD6ENSG00000188243.8322.79050453.72800-0.491203.003702.18760HepG2FUBP3
COMMD6ENSG00000188243.8634.457701031.77930-0.701506.848305.79090HepG2FXR1
COMMD6ENSG00000188243.8578.39080957.20540-0.726806.773505.75240HepG2G3BP1
COMMD6ENSG00000188243.8451.26410282.042300.678004.957804.12660HepG2HNRNPA1
COMMD6ENSG00000188243.8818.73430596.296200.457304.920203.73220HepG2HNRNPA2B1
COMMD6ENSG00000188243.8664.53330969.07310-0.544304.705903.81640HepG2HNRNPK
COMMD6ENSG00000188243.8737.30100591.036300.318902.889802.20370HepG2HNRNPL
COMMD6ENSG00000188243.8328.76970217.743700.594303.072602.41350HepG2HNRNPLL
COMMD6ENSG00000188243.8750.22340973.00650-0.375102.345401.71820HepG2IGF2BP2
COMMD6ENSG00000188243.8432.17190318.331200.441003.451802.63980HepG2ILF2
COMMD6ENSG00000188243.8536.590401032.13880-0.9437011.3456010.04880HepG2MAGOH
COMMD6ENSG00000188243.8784.711301037.93990-0.403502.419101.82660HepG2MATR3
COMMD6ENSG00000188243.8410.41310311.601500.397302.067501.36330HepG2MSI2
COMMD6ENSG00000188243.8537.196401062.40910-0.9838011.8357010.56740HepG2NCBP2
COMMD6ENSG00000188243.8782.17620643.380900.281701.982801.33430HepG2NOL12
COMMD6ENSG00000188243.8112.18370377.17840-1.7494011.041608.79510HepG2NONO
COMMD6ENSG00000188243.8253.93460610.35450-1.265204.196901.89490HepG2NUFIP2
COMMD6ENSG00000188243.8592.27740946.23570-0.675906.118505.05710HepG2PABPC4
COMMD6ENSG00000188243.8395.55040308.478000.358602.125101.37490HepG2PARN
COMMD6ENSG00000188243.8656.77710979.63980-0.576805.978705.13990HepG2PCBP1
COMMD6ENSG00000188243.8505.96580316.916600.674804.686803.66570HepG2PRPF8
COMMD6ENSG00000188243.8461.67160996.88710-1.1106023.0203021.73320HepG2PTBP1
COMMD6ENSG00000188243.8604.116401079.51050-0.8375013.6680012.43120HepG2QKI
COMMD6ENSG00000188243.8997.83590703.717500.503705.949705.26190HepG2RBM22
COMMD6ENSG00000188243.8529.30430979.77920-0.8884012.9369011.53930HepG2RBM25
COMMD6ENSG00000188243.8590.77100454.193100.379202.198801.32440HepG2RBM27
COMMD6ENSG00000188243.8658.313201109.38400-0.7529011.6686010.70540HepG2NELFE
COMMD6ENSG00000188243.8616.098801033.34140-0.7461011.5888010.45770HepG2RECQL
COMMD6ENSG00000188243.8352.90880537.07470-0.605803.424502.53400HepG2RPS3A
COMMD6ENSG00000188243.8294.18720593.95920-1.013602.918701.51990HepG2SF1
COMMD6ENSG00000188243.8657.238801037.76800-0.6590010.272309.24090HepG2SF3B4
COMMD6ENSG00000188243.8215.13170530.24060-1.301404.671602.86660HepG2SNRNP200
COMMD6ENSG00000188243.8672.66810794.81840-0.240701.778001.34920HepG2SRFBP1
COMMD6ENSG00000188243.8625.885501083.25410-0.7914014.8082013.89970HepG2SRSF1
COMMD6ENSG00000188243.8646.42360881.32720-0.447205.301204.58150HepG2SRSF9
COMMD6ENSG00000188243.8657.93250973.80720-0.565703.610302.98530HepG2TAF15
COMMD6ENSG00000188243.8362.98560212.213100.774305.228004.27610HepG2TARDBP
COMMD6ENSG00000188243.8591.62040894.65170-0.596706.620505.33140HepG2TIA1
COMMD6ENSG00000188243.8393.03510305.522200.363302.227701.71070HepG2TRIM56
COMMD6ENSG00000188243.8282.45100617.56890-1.128603.484402.37360HepG2U2AF2
COMMD6ENSG00000188243.8342.19280241.577900.502202.647501.90610HepG2UCHL5
COMMD6ENSG00000188243.8575.49260374.484600.619803.460002.33030HepG2UPF2
COMMD6ENSG00000188243.8661.37120402.553800.716205.759004.72510HepG2XRN2
COMMD6ENSG00000188243.8372.32300265.197800.489402.585801.41160K562ABCF1
COMMD6ENSG00000188243.8512.39450331.067300.630006.251605.45160K562AGGF1
COMMD6ENSG00000188243.8515.84290363.807300.503703.660402.49290K562AKAP8
COMMD6ENSG00000188243.8449.33530344.494100.383202.183501.60040K562AKAP8L
COMMD6ENSG00000188243.8646.44310513.753600.331301.917701.41230K562AQR
COMMD6ENSG00000188243.8528.81100361.463900.548805.068103.78980K562ATP5C1
COMMD6ENSG00000188243.8270.02490170.235700.665503.198702.25990K562BOP1
COMMD6ENSG00000188243.8593.80670383.358900.631205.330503.56670K562CIRBP
COMMD6ENSG00000188243.8283.34340180.988300.646603.620802.72480K562CPSF6
COMMD6ENSG00000188243.8905.78070632.452900.518103.876002.70990K562CELF1
COMMD6ENSG00000188243.8466.38840370.678100.331302.130901.37380K562DKC1
COMMD6ENSG00000188243.8177.43170246.95510-0.477002.354201.61710K562EIF3G
COMMD6ENSG00000188243.8236.42500333.70190-0.497202.652001.84920K562EIF4A3
COMMD6ENSG00000188243.8301.75930190.659000.662303.962102.93570K562FIP1L1
COMMD6ENSG00000188243.8287.39690181.720800.661203.375702.11290K562FKBP4
COMMD6ENSG00000188243.8259.59620347.03820-0.418802.247701.69200K562FXR1
COMMD6ENSG00000188243.8275.59600172.782400.673503.590402.69040K562GPKOW
COMMD6ENSG00000188243.8710.22330380.896900.898809.955908.49720K562GRSF1
COMMD6ENSG00000188243.8430.41530325.391100.403502.370001.37980K562HNRNPA1
COMMD6ENSG00000188243.8248.67930156.833900.664903.091102.10300K562HNRNPM
COMMD6ENSG00000188243.8500.96840258.473400.954609.025207.60270K562HSPD1
COMMD6ENSG00000188243.8496.02670357.518500.472302.389501.45620K562IGF2BP2
COMMD6ENSG00000188243.8586.48640365.581900.681806.324104.96010K562KIF1C
COMMD6ENSG00000188243.8295.34430147.578801.000805.578904.19490K562KRR1
COMMD6ENSG00000188243.8545.51570409.545800.413502.836401.91310K562MBNL1
COMMD6ENSG00000188243.8313.49140227.780100.460702.518201.74550K562MTPAP
COMMD6ENSG00000188243.8468.11280287.063000.705404.141603.00240K562NAA15
COMMD6ENSG00000188243.8794.80430562.536400.498603.379001.70740K562NOL12
COMMD6ENSG00000188243.8140.14010227.06890-0.696303.162701.75700K562NONO
COMMD6ENSG00000188243.8345.70290253.116500.449602.765002.01890K562NSUN2
COMMD6ENSG00000188243.8359.80430216.456000.733005.131103.95840K562PPIG
COMMD6ENSG00000188243.8239.81170365.20970-0.606802.522601.88460K562PTBP1
COMMD6ENSG00000188243.8890.40230596.910000.576805.461003.91900K562PUM1
COMMD6ENSG00000188243.8792.15480584.677000.438003.374602.31340K562PUM2
COMMD6ENSG00000188243.8687.02030341.618301.0079011.7357010.66570K562PUS1
COMMD6ENSG00000188243.8491.86460332.876500.563204.719503.96500K562RBM15
COMMD6ENSG00000188243.8175.26640300.85910-0.779503.378201.61310K562RPS3A
COMMD6ENSG00000188243.8343.30730228.768400.585503.135001.79180K562STAU1
COMMD6ENSG00000188243.8329.05520222.955000.561502.996101.54290K562TRIP6
COMMD6ENSG00000188243.8315.50760202.920100.636703.294201.97830K562UTP3
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for COMMD6 is not available on ENCORE database.





6 RBPs can affect the splicing of COMMD6 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SECOMMD6ENSG00000188243.8chr13-761042497610432376100571761007757610444676104541-0.161000.000000.00010excludedHepG2RBM22
SECOMMD6ENSG00000188243.8chr13-761042497610432376100571761007757610444676104541-0.230000.000240.00567excludedK562HNRNPC
MXECOMMD6ENSG00000188243.8chr13-76104249761044027610444676104544761005717610077576111799761118110.054000.000400.017681includedK562PTBP1
MXECOMMD6ENSG00000188243.8chr13-76104249761044027610444676104544761005717610077576111799761118110.100000.001120.055091includedK562SF3B1
MXECOMMD6ENSG00000188243.8chr13-76104249761044027610444676104541761005717610077576111799761118110.055000.001020.043981includedK562FXR1
MXECOMMD6ENSG00000188243.8chr13-76104249761044027610444676104541761005717610077576111799761118110.131000.000000.000201includedK562HNRNPC
MXECOMMD6ENSG00000188243.8chr13-76104249761044027610444676104544761005717610077576111799761118110.092000.000020.000871includedK562HNRNPC
MXECOMMD6ENSG00000188243.8chr13-76104249761044027610444676104541761005717610077576111799761118110.063000.000010.009131includedK562APOBEC3C

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for COMMD6 is not avaliable on ENCORE database.