ALG1

General Information

Gene Name       : ALG1
Gene ID             : ENSG00000033011.12
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: ALG1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878ALG1ENSG00000033011.1211.2814.5712.93ENCSR000AEF
HepG2ALG1ENSG00000033011.1261.0250.8055.91ENCSR985KAT
K562ALG1ENSG00000033011.1213.2412.8013.02ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for ALG1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • ALG1 RNA is bound by 10 proteins.  







eCLIP assay for ALG1 is not avaliable on ENCORE database.





10 proteins are bound to ALG1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr1651287565128878+3'-UTR,CDS,intron-Proximal4.6055413.56113HepG2SND1
chr1651351875135223+3'-UTR3.768755.80891HepG2LARP4
chr1651351005135229+3'-UTR3.8353911.59320HepG2AKAP1
chr1651231535123183+3'-UTR,5'-UTR,CDS,intron-Proximal4.073673.79199HepG2PPIG
chr1651349315134982+3'-UTR3.361594.48159HepG2LARP4
chr1651230035123083+3'-UTR,5'-UTR,CDS,intron-Proximal4.015198.47339HepG2PRPF8
chr1651337245133817+3'-UTR,CDS,intron-Proximal3.840548.78144HepG2PRPF8
chr1651229925123030+3'-UTR,5'-UTR,CDS,intron-Proximal3.622704.66892HepG2SND1
chr1651351155135187+3'-UTR3.701288.91984HepG2LARP4
chr1651288755128927+3'-UTR,CDS,intron-Proximal3.368626.29405HepG2PRPF8
chr1651351175135236+3'-UTR4.7523219.67301HepG2UPF1
chr1651352365135282+3'-UTR3.438055.69025HepG2UPF1
chr1651231535123181+3'-UTR,5'-UTR,CDS,intron-Proximal3.596944.39950HepG2SND1
chr1651287755128872+3'-UTR,CDS4.5689510.11508HepG2RPS3
chr1651279385128002+5'-UTR,CDS3.884769.53068HepG2SND1
chr1651220385122106+5'-UTR,CDS,intron-Distal,intron-Proximal4.173989.70941HepG2PRPF8
chr1651280035128018+5'-UTR,CDS3.542473.57831HepG2SND1
chr1651232055123232+5'-UTR,CDS3.694905.56131HepG2SND1
chr1651254735125535+5'-UTR,CDS3.083704.12519HepG2SND1
chr1651232455123257+5'-UTR,CDS3.8989710.58080HepG2SND1
chr1651253865125459+5'-UTR,CDS,intron-Proximal5.865519.89347HepG2RPS3
chr1651274975127536+5'-UTR,CDS,intron-Proximal3.935977.49297HepG2SND1
chr1651253875125456+5'-UTR,CDS,intron-Proximal4.7583918.63595HepG2SND1
chr1651232185123308+5'-UTR,CDS,intron-Proximal3.563557.92471HepG2PRPF8
chr1651219675122056+CDS,intron-Distal4.099659.65734HepG2RPS3
chr1651218625121986+CDS,intron-Distal4.1703348.20578HepG2DDX3X
chr1651218555121967+CDS,intron-Distal3.8160219.33496HepG2RPS3
chr1651360365136072+intron-Distal4.497244.19989HepG2UPF1
chr1651289885129014+intron-Proximal4.6708511.29890HepG2RBFOX2
chr1651289245129000+intron-Proximal5.619367.24749HepG2EFTUD2
chr1651289535128988+intron-Proximal4.0999010.67734HepG2RBFOX2
chr1651364615136519+intron-Proximal4.715348.81141HepG2UPF1
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for ALG1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for ALG1 is not available on ENCORE database.

  • 78 RBPs can affect the levels of ALG1.  








The Knockdown/knockout RNA-Seq assay for ALG1 is not available on ENCORE database.





78 RBPs can affect the gene expression of ALG1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
ALG1ENSG00000033011.71360.44120941.881000.530404.391803.22610HepG2ABCF1
ALG1ENSG00000033011.7619.66200973.57710-0.651805.921504.79480HepG2ASCC1
ALG1ENSG00000033011.71123.026301336.79070-0.251402.324801.68650HepG2AUH
ALG1ENSG00000033011.71075.36640815.050800.399803.172502.53630HepG2BOP1
ALG1ENSG00000033011.7799.503301063.91470-0.412202.287701.41010HepG2CCAR1
ALG1ENSG00000033011.71228.73530924.967400.409603.037702.22890HepG2CIRBP
ALG1ENSG00000033011.7715.65470399.489300.841005.424404.35010HepG2CNOT7
ALG1ENSG00000033011.71543.030701127.132900.453003.599902.89720HepG2DDX3X
ALG1ENSG00000033011.7667.63500889.21820-0.413502.560501.81250HepG2DDX55
ALG1ENSG00000033011.7547.06100849.70710-0.635303.095902.06340HepG2DDX59
ALG1ENSG00000033011.7738.68300968.26390-0.390402.132101.58250HepG2DDX6
ALG1ENSG00000033011.7920.37130593.611600.632605.474504.21400HepG2EEF2
ALG1ENSG00000033011.71892.251701028.607900.8793010.693809.46260HepG2EIF4A3
ALG1ENSG00000033011.7647.700001001.52480-0.628804.123403.29180HepG2EIF4B
ALG1ENSG00000033011.7923.648501143.31950-0.307802.914102.05890HepG2EIF4G1
ALG1ENSG00000033011.71314.818501534.86480-0.223202.360801.79760HepG2ETF1
ALG1ENSG00000033011.7549.95880700.30940-0.348702.191701.48490HepG2FUBP3
ALG1ENSG00000033011.7607.82850848.22060-0.480803.145702.46810HepG2GPKOW
ALG1ENSG00000033011.7578.93580369.774500.646703.657702.37530HepG2GRSF1
ALG1ENSG00000033011.7975.55400721.116000.435903.459802.69030HepG2HNRNPC
ALG1ENSG00000033011.7952.331101177.23140-0.305903.227202.45780HepG2HNRNPF
ALG1ENSG00000033011.71334.21990974.933100.452503.925603.10720HepG2HNRNPK
ALG1ENSG00000033011.7895.85250656.200700.449003.928302.81400HepG2HNRNPM
ALG1ENSG00000033011.71280.12930978.607100.387402.807102.12740HepG2IGF2BP2
ALG1ENSG00000033011.71527.927901123.786300.443102.877302.03070HepG2LARP4
ALG1ENSG00000033011.7952.18320693.751300.456703.298901.97390HepG2LIN28B
ALG1ENSG00000033011.71748.666101038.233400.752009.039407.86710HepG2MAGOH
ALG1ENSG00000033011.71920.203301044.036400.8790010.916309.72400HepG2MATR3
ALG1ENSG00000033011.71454.079301068.622800.444303.329502.63660HepG2NCBP2
ALG1ENSG00000033011.7409.56590717.74740-0.809407.880706.66340HepG2NSUN2
ALG1ENSG00000033011.7223.03100365.07230-0.710903.161702.20790HepG2PABPC1
ALG1ENSG00000033011.7853.61050709.073200.267502.159201.40360HepG2PARN
ALG1ENSG00000033011.71350.820501007.240100.423305.867205.03590HepG2PCBP1
ALG1ENSG00000033011.7647.09600808.58050-0.321402.716801.94890HepG2PRPF4
ALG1ENSG00000033011.7465.38050685.80810-0.559404.140303.17550HepG2PRPF8
ALG1ENSG00000033011.71368.993401096.903000.319602.709202.11850HepG2PUF60
ALG1ENSG00000033011.71555.478901164.454800.417608.367707.45270HepG2PUM1
ALG1ENSG00000033011.71162.37850905.557200.360104.587403.83200HepG2PUS1
ALG1ENSG00000033011.7602.585001110.04330-0.8814015.8966014.57730HepG2QKI
ALG1ENSG00000033011.7774.78570999.80180-0.367803.347202.41250HepG2RBM15
ALG1ENSG00000033011.7925.47080647.191500.515903.536402.33800HepG2RCC2
ALG1ENSG00000033011.7806.38760468.892700.782109.340208.29000HepG2RPS19
ALG1ENSG00000033011.7959.97020734.988500.385202.277001.54590HepG2RPS2
ALG1ENSG00000033011.7674.04620400.960800.749305.247904.14300HepG2RPS3A
ALG1ENSG00000033011.71021.34600750.312300.444802.934901.82660HepG2RPS5
ALG1ENSG00000033011.7494.18130678.39130-0.457102.769101.98200HepG2RRP9
ALG1ENSG00000033011.7653.92580470.559900.474603.061002.07030HepG2SERBP1
ALG1ENSG00000033011.71734.790001050.366600.723806.562205.49760HepG2SF3A3
ALG1ENSG00000033011.7896.824301067.09120-0.250802.286601.74230HepG2SF3B4
ALG1ENSG00000033011.7978.83290743.960300.395704.190303.42790HepG2SMN1
ALG1ENSG00000033011.71081.252301448.91620-0.422306.625105.94210HepG2SRFBP1
ALG1ENSG00000033011.71631.670601083.084400.5911012.4593011.26080HepG2SRSF5
ALG1ENSG00000033011.7462.44640885.15890-0.9367010.076808.92040HepG2SUPV3L1
ALG1ENSG00000033011.7505.069801001.01890-0.9869020.0013018.69200HepG2TAF15
ALG1ENSG00000033011.71287.15730633.906201.021704.871403.48520HepG2TBRG4
ALG1ENSG00000033011.7796.87410593.264200.425602.555701.59300HepG2TFIP11
ALG1ENSG00000033011.7657.26770919.89530-0.485004.964203.85360HepG2TIA1
ALG1ENSG00000033011.7867.47410696.097900.317402.390401.91960HepG2TIAL1
ALG1ENSG00000033011.7853.14470702.287300.280602.398801.86620HepG2TRIM56
ALG1ENSG00000033011.71055.96890899.342900.231501.988601.46330HepG2UTP3
ALG1ENSG00000033011.7672.06960871.34320-0.374602.471201.78290HepG2XRN2
ALG1ENSG00000033011.7676.02560797.96200-0.239201.914401.34140HepG2ZC3H8
ALG1ENSG00000033011.71517.863701024.488900.5670013.2234012.25240HepG2ZNF622
ALG1ENSG00000033011.7568.53270377.612400.590205.008703.25780K562APOBEC3C
ALG1ENSG00000033011.7194.26440139.856700.474002.039001.34760K562EIF3G
ALG1ENSG00000033011.7224.75780114.483000.973105.883304.69470K562EIF4A3
ALG1ENSG00000033011.7324.88830119.055001.4482012.1178010.94450K562FXR1
ALG1ENSG00000033011.7200.22100129.536400.628102.496301.32870K562HNRNPK
ALG1ENSG00000033011.793.57860162.27410-0.794202.657501.74540K562KRR1
ALG1ENSG00000033011.7248.66270136.305600.867203.195502.28860K562MAGOH
ALG1ENSG00000033011.7205.54600136.029800.595402.790301.86370K562MATR3
ALG1ENSG00000033011.7234.67720305.40060-0.380002.043001.39030K562NSUN2
ALG1ENSG00000033011.7285.99980132.429001.110709.847008.64960K562PTBP1
ALG1ENSG00000033011.7235.39080126.986300.890305.605804.35940K562RBM22
ALG1ENSG00000033011.7143.1993065.660601.124803.849702.64480K562RPS3
ALG1ENSG00000033011.7328.74630208.630900.655904.023102.70750K562SAFB
ALG1ENSG00000033011.7116.80860180.74440-0.629802.168801.31830K562SF3B1
ALG1ENSG00000033011.7239.98420129.824100.886305.416404.43380K562SRSF1
ALG1ENSG00000033011.7240.22760359.87380-0.583103.186401.82710K562STAU1
ALG1ENSG00000033011.7375.92000234.866700.678505.075803.95520K562SYNCRIP
ALG1ENSG00000033011.7231.29870131.391600.815804.549903.63820K562TARDBP
ALG1ENSG00000033011.7161.94890277.08600-0.774805.071603.86920K562WDR3
ALG1ENSG00000033011.7219.19740288.12020-0.394402.155601.40130K562WDR43
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for ALG1 is not available on ENCORE database.





4 RBPs can affect the splicing of ALG1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEALG1ENSG00000033011.7chr16+512906451291035128757512887951297485129808-0.128000.000000.00004excludedHepG2U2AF1
SEALG1ENSG00000033011.7chr16+513368251337585132559513267451347505135019-0.355000.000000.00000excludedHepG2U2AF1
SEALG1ENSG00000033011.7chr16+513368251337585132559513267451347505135019-0.303000.000000.00004excludedHepG2U2AF2
SEALG1ENSG00000033011.7chr16+513368251337585132559513267451347505135019-0.087000.000820.02161excludedHepG2SRSF1
MXEALG1ENSG00000033011.7chr16+51290645129103512974851298085128757512887951309465131057-0.121000.000760.030112includedHepG2SF3A3

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for ALG1 is not avaliable on ENCORE database.