UNC5B

General Information

Gene Name       : UNC5B
Gene ID             : ENSG00000107731.12
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: UNC5B)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878UNC5BENSG00000107731.120.000.000.00ENCSR000AEF
HepG2UNC5BENSG00000107731.120.110.040.07ENCSR985KAT
K562UNC5BENSG00000107731.125.203.624.41ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for UNC5B is not avaliable on ENCORE database.



Proteins bound to RNA
  • UNC5B RNA is bound by 8 proteins.  







eCLIP assay for UNC5B is not avaliable on ENCORE database.





8 proteins are bound to UNC5B RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr107305979673059860+3'-UTR3.344823.66454K562IGF2BP1
chr107306202673062077+3'-UTR5.239304.66266K562TARDBP
chr107305981173059878+3'-UTR5.9414813.38240K562EIF4G2
chr107306206273062079+3'-UTR5.2238016.27966K562EIF4G2
chr107306213373062195+3'-UTR3.121375.09741K562UPF1
chr107305979273059877+3'-UTR4.937578.74918K562TARDBP
chr107305973973059799+3'-UTR3.845176.81502K562EIF4G2
chr107306212273062170+3'-UTR4.347163.60944K562TARDBP
chr107305942873059499+3'-UTR4.9621911.42369K562TIA1
chr107306214173062243+3'-UTR4.554294.46951K562FAM120A
chr107306202673062091+3'-UTR5.108386.99975K562UPF1
chr107306207973062166+3'-UTR5.1594310.97759K562EIF4G2
chr107306202173062062+3'-UTR4.8518813.53984K562EIF4G2
chr107305988773059956+3'-UTR5.461218.40676K562UPF1
chr107305979173059887+3'-UTR5.3440929.07999K562UPF1
chr107306216673062217+3'-UTR4.670448.13013K562EIF4G2
chr107297432672974403+intron-Distal4.704256.09301K562CSTF2T
chr107298192472982040+intron-Distal5.120684.67055K562EIF4G2
chr107298194972982000+intron-Distal3.261573.74491K562CSTF2T
chr107297385572973886+intron-Distal3.932093.59342K562CSTF2T
chr107297610472976175+intron-Distal4.144347.56606K562CSTF2T
chr107297351272973564+intron-Distal3.190567.10530K562CSTF2T
chr107298743972987524+intron-Distal4.385674.46313K562HNRNPL
chr107298753272987612+intron-Distal4.656624.66841K562HNRNPL
chr107297411072974156+intron-Distal4.609325.01722K562CSTF2T
chr107297795472978012+intron-Distal3.882156.67564K562CSTF2T
chr107297758572977639+intron-Distal3.733213.56210K562EIF4G2
chr107297348772973565+intron-Distal5.3941712.89962K562EIF4G2
chr107297803072978104+intron-Distal5.359778.39137K562CSTF2T
chr107297284672972882+intron-Proximal3.165253.25653K562CSTF2T
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for UNC5B is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for UNC5B is not available on ENCORE database.

  • 92 RBPs can affect the levels of UNC5B.  








The Knockdown/knockout RNA-Seq assay for UNC5B is not available on ENCORE database.





92 RBPs can affect the gene expression of UNC5B :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
UNC5BENSG00000107731.851.3816010.392102.305706.233605.12520HepG2AKAP8L
UNC5BENSG00000107731.831.178105.533802.494103.985403.28130HepG2BOP1
UNC5BENSG00000107731.822.238305.080402.129902.502101.84260HepG2CPSF6
UNC5BENSG00000107731.873.059708.083003.176009.294908.07300HepG2EIF4B
UNC5BENSG00000107731.8219.3787010.721404.3548044.8100042.94300HepG2ETF1
UNC5BENSG00000107731.825.105209.134001.458602.315401.65500HepG2HNRNPF
UNC5BENSG00000107731.831.534408.995201.809602.919102.17680HepG2IGF2BP1
UNC5BENSG00000107731.879.396908.429903.2354010.758909.57420HepG2MATR3
UNC5BENSG00000107731.822.899104.117602.475302.829002.01050HepG2PRPF8
UNC5BENSG00000107731.833.167404.154002.997103.137502.50900HepG2PUF60
UNC5BENSG00000107731.8187.329804.407305.4095048.0358045.55300HepG2PUM2
UNC5BENSG00000107731.825.334608.962401.499101.920001.46750HepG2RBM22
UNC5BENSG00000107731.838.619909.826901.974404.192203.37860HepG2RPLP0
UNC5BENSG00000107731.812.260000.451704.762302.467601.70860HepG2RPS2
UNC5BENSG00000107731.820.345205.275301.947302.027701.34300HepG2RPS3A
UNC5BENSG00000107731.827.148205.440402.319003.169102.41630HepG2SF3B1
UNC5BENSG00000107731.823.924004.524802.402402.818202.22210HepG2SF3B4
UNC5BENSG00000107731.845.774308.970902.351106.879905.86390HepG2SRSF7
UNC5BENSG00000107731.829.862607.107302.070903.052401.70600HepG2SSRP1
UNC5BENSG00000107731.854.339406.980202.960606.408804.86050HepG2TBRG4
UNC5BENSG00000107731.81089.066301625.19280-0.577505.818205.04370K562AGGF1
UNC5BENSG00000107731.8487.243401691.07720-1.7952051.9150048.51690K562AKAP8L
UNC5BENSG00000107731.8577.520701774.32900-1.6193061.0729056.97670K562ATP5C1
UNC5BENSG00000107731.8130.8446043.249001.597003.688502.57370K562BCLAF1
UNC5BENSG00000107731.8282.63860133.614501.080807.126705.70600K562BOP1
UNC5BENSG00000107731.8204.02210103.458400.979605.024203.02670K562BUD13
UNC5BENSG00000107731.81066.655901942.22580-0.864603.958302.51500K562CCDC124
UNC5BENSG00000107731.8247.40240163.191300.600203.223501.58570K562CEBPZ
UNC5BENSG00000107731.8375.02510229.761200.706804.251702.39560K562CKAP4
UNC5BENSG00000107731.8371.4441093.041501.9971016.4497013.93920K562CNOT7
UNC5BENSG00000107731.8477.70650142.059201.7495025.6088023.18690K562CPSF6
UNC5BENSG00000107731.8945.105901906.79530-1.0126018.7318015.33080K562DDX19B
UNC5BENSG00000107731.8359.20260187.565900.937303.178501.87410K562DDX21
UNC5BENSG00000107731.839.14580106.74140-1.447205.554804.67890K562DDX47
UNC5BENSG00000107731.8277.03410118.604501.2238011.641908.79700K562DDX6
UNC5BENSG00000107731.81917.31470136.816903.80870229.97310226.35630K562EIF2S2
UNC5BENSG00000107731.826.3593066.48560-1.334702.643101.66550K562EIF3A
UNC5BENSG00000107731.821.3265054.72110-1.359503.275502.41230K562EIF3G
UNC5BENSG00000107731.8252.33990113.545401.152006.619504.03640K562ESF1
UNC5BENSG00000107731.8407.95870144.563901.4966016.0639013.93130K562FMR1
UNC5BENSG00000107731.8381.47690122.540601.6382017.3668014.89640K562FTO
UNC5BENSG00000107731.821.29180127.10280-2.5776015.8910014.55140K562FXR1
UNC5BENSG00000107731.8260.00220102.282101.345906.416403.24800K562FXR2
UNC5BENSG00000107731.8107.0648037.068101.530105.609903.56400K562GEMIN5
UNC5BENSG00000107731.8192.17080117.447500.710303.487102.20750K562GLRX3
UNC5BENSG00000107731.8501.52010135.622401.8866027.8621025.15080K562GPKOW
UNC5BENSG00000107731.8400.15780182.263401.134403.105202.30680K562GRSF1
UNC5BENSG00000107731.8159.9923069.207701.208902.888701.79270K562HNRNPA1
UNC5BENSG00000107731.8182.2207039.702002.1983015.2035013.88770K562HNRNPC
UNC5BENSG00000107731.8124.2533076.633400.697102.399801.56700K562HNRNPU
UNC5BENSG00000107731.82618.38210144.749604.17690200.87370196.47580K562HSPD1
UNC5BENSG00000107731.8158.4191078.900701.005502.937801.87180K562IGF2BP2
UNC5BENSG00000107731.8678.831101794.68920-1.402608.718907.04380K562KIF1C
UNC5BENSG00000107731.81207.266102010.50050-0.7358013.8838011.61150K562MBNL1
UNC5BENSG00000107731.8489.35000132.386501.8860028.3625025.60750K562METAP2
UNC5BENSG00000107731.8337.87850123.477301.4522015.7209014.00020K562MTPAP
UNC5BENSG00000107731.8404.105101409.21230-1.8021011.754409.43960K562NAA15
UNC5BENSG00000107731.876.4899036.484101.067902.546901.32080K562NONO
UNC5BENSG00000107731.8493.91970137.213701.8478035.8780033.70050K562NSUN2
UNC5BENSG00000107731.872.00580164.37630-1.190805.668804.47180K562PCBP3
UNC5BENSG00000107731.842.24790126.08000-1.577407.859306.53290K562POLR2G
UNC5BENSG00000107731.8259.85450121.223301.099907.890906.34830K562PPIG
UNC5BENSG00000107731.8164.0027035.608302.2033014.2736011.88610K562PSIP1
UNC5BENSG00000107731.825.4950080.59820-1.660506.393805.41940K562PTBP1
UNC5BENSG00000107731.8267.90730149.535900.841104.597103.35000K562PUM2
UNC5BENSG00000107731.8127.737501677.15330-3.71480138.93480135.01150K562PUS1
UNC5BENSG00000107731.8197.0529069.751601.498203.653101.41820K562RBFOX2
UNC5BENSG00000107731.8243.845201634.07630-2.74440124.63730120.71820K562RBM15
UNC5BENSG00000107731.81074.14160516.915501.055104.297202.26200K562RBM39
UNC5BENSG00000107731.836.4164081.34650-1.159503.621802.34990K562NELFE
UNC5BENSG00000107731.864.05240112.34730-0.810602.518801.48680K562SAFB
UNC5BENSG00000107731.848.03600116.15090-1.273805.200603.21610K562SDAD1
UNC5BENSG00000107731.8388.03950135.366101.5192020.0959018.06740K562SF3A3
UNC5BENSG00000107731.8204.87120129.015000.667102.585201.64720K562SF3B1
UNC5BENSG00000107731.8105.4582052.755900.999203.843402.83010K562SF3B4
UNC5BENSG00000107731.81036.96810468.993801.144607.353204.83840K562SFPQ
UNC5BENSG00000107731.8126.2829071.976500.811002.633701.40340K562SLBP
UNC5BENSG00000107731.898.0009035.947801.446805.112102.81970K562SRP68
UNC5BENSG00000107731.863.02540138.68290-1.137805.598404.32620K562SRPK2
UNC5BENSG00000107731.823.8825079.00880-1.726105.751704.74020K562SRSF1
UNC5BENSG00000107731.8847.42580353.672401.260607.118505.30760K562SRSF4
UNC5BENSG00000107731.8175.0325074.607101.230107.360005.54500K562SRSF5
UNC5BENSG00000107731.8258.55980167.380100.627303.751602.37960K562SRSF7
UNC5BENSG00000107731.887.16440143.50690-0.719302.988801.40440K562SRSF9
UNC5BENSG00000107731.8300.3436056.443502.411602.885701.57740K562SSB
UNC5BENSG00000107731.8226.72870128.112600.823504.136102.54910K562STAU1
UNC5BENSG00000107731.8172.4390082.987301.055003.428401.59550K562STIP1
UNC5BENSG00000107731.831.69370126.46460-1.9965011.243309.59700K562SYNCRIP
UNC5BENSG00000107731.8186.7305077.139001.275304.274003.22360K562TIA1
UNC5BENSG00000107731.8168.9605034.242602.3027015.3787013.05780K562TIAL1
UNC5BENSG00000107731.8234.52950124.851800.909505.257303.21090K562TRIP6
UNC5BENSG00000107731.8130.4503036.851001.823608.575106.70970K562UCHL5
UNC5BENSG00000107731.8420.76460145.489101.5320021.8395020.06020K562UPF1
UNC5BENSG00000107731.8225.7724091.763801.298808.741206.71950K562UTP3
UNC5BENSG00000107731.8286.36630124.492901.2017010.354208.62100K562WDR3
UNC5BENSG00000107731.867.93120129.44100-0.930104.291103.25370K562WDR43
UNC5BENSG00000107731.820.93610130.03540-2.634803.443501.62800K562XRCC6
UNC5BENSG00000107731.8133.8332037.547901.833503.494802.07740K562XRN2
UNC5BENSG00000107731.8375.93020140.954101.4151011.415609.52480K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for UNC5B is not available on ENCORE database.





1 RBPs can affect the splicing of UNC5B :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
A3SSUNC5BENSG00000107731.8chr10+730531617305333073053172730533307305222373052311-0.084000.000540.02911shorterK562PUS1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for UNC5B is not avaliable on ENCORE database.