TMEM222

General Information

Gene Name       : TMEM222
Gene ID             : ENSG00000186501.14
Essential Gene : No

Functions

Localization

Domains (AlphaFold: TMEM222)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878TMEM222ENSG00000186501.147.2122.4014.80ENCSR000AEF
HepG2TMEM222ENSG00000186501.1430.1414.8122.48ENCSR985KAT
K562TMEM222ENSG00000186501.1441.1532.2636.70ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for TMEM222 is not avaliable on ENCORE database.



Proteins bound to RNA
  • TMEM222 RNA is bound by 14 proteins.  







eCLIP assay for TMEM222 is not avaliable on ENCORE database.





14 proteins are bound to TMEM222 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr12766263027662749+3'-UTR5.1069312.41865HepG2AKAP1
chr12766221227662277+3'-UTR4.179753.15159HepG2LARP4
chr12766045027660499+3'-UTR,CDS4.100294.48692K562YBX3
chr12766257727662670+3'-UTR3.8923812.46167K562UPF1
chr12766261527662733+3'-UTR6.1443017.20564HepG2UPF1
chr12766244427662495+3'-UTR4.876146.20043HepG2UPF1
chr12766258227662693+3'-UTR4.040823.44763HepG2LSM11
chr12765857027658671+3'-UTR,CDS,intron-Proximal3.091954.21588K562PRPF8
chr12766212727662193+3'-UTR4.6680110.54173HepG2AKAP1
chr12766260927662750+3'-UTR4.298094.25576HepG2PABPN1
chr12766211527662183+3'-UTR5.6801713.55250HepG2UPF1
chr12766279527662853+3'-UTR3.743638.41991HepG2AKAP1
chr12766202927662106+3'-UTR4.421744.01795HepG2LARP4
chr12766220927662298+3'-UTR6.6890225.48081HepG2UPF1
chr12766279327662858+3'-UTR4.6711410.21308K562UPF1
chr12766243827662498+3'-UTR3.525057.91779K562UPF1
chr12766213027662208+3'-UTR5.4138517.95756K562UPF1
chr12766202927662107+3'-UTR4.6989215.52312K562UPF1
chr12766202727662115+3'-UTR6.4931322.61753HepG2UPF1
chr12766268727662735+3'-UTR4.711479.04751K562UPF1
chr12766220827662286+3'-UTR4.2292612.64844HepG2AKAP1
chr12766229227662377+3'-UTR6.6070623.84312K562UPF1
chr12766230927662368+3'-UTR5.7868014.89968HepG2UPF1
chr12766230927662367+3'-UTR4.503367.98114HepG2AKAP1
chr12765858427658655+3'-UTR,CDS,intron-Proximal3.610149.22568K562AQR
chr12766202927662103+3'-UTR5.9854411.85767HepG2AKAP1
chr12766220827662292+3'-UTR5.5763619.73459K562UPF1
chr12765853427658642+3'-UTR,CDS,intron-Proximal4.782514.28193HepG2AQR
chr12764872227648850+5'-UTR,CDS4.7583910.10446K562DDX3X
chr12765725627657365+CDS,intron-Proximal6.0064611.46503HepG2PRPF8
chr12765721027657293+CDS,intron-Proximal3.179685.58482K562YBX3
chr12765726227657362+CDS,intron-Proximal3.278986.09777K562PRPF8
chr12765129127651354+intron-Distal3.831783.01428K562UCHL5
chr12765771427657814+intron-Distal,intron-Proximal3.781204.58287K562PRPF8
chr12765173427651789+intron-Distal5.138875.97591K562QKI
chr12765178527651816+intron-Distal6.6114920.36044K562SMNDC1
chr12765178727651824+intron-Distal4.935265.50038K562RBM22
chr12765183427651863+intron-Distal4.494914.82934K562RBM15
chr12765176827651807+intron-Distal4.652459.27995K562PRPF8
chr12765729527657382+intron-Proximal3.623634.41130K562AQR
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for TMEM222 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for TMEM222 is not available on ENCORE database.

  • 78 RBPs can affect the levels of TMEM222.  








The Knockdown/knockout RNA-Seq assay for TMEM222 is not available on ENCORE database.





78 RBPs can affect the gene expression of TMEM222 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
TMEM222ENSG00000186501.10612.34720434.711400.494202.192901.35000HepG2ABCF1
TMEM222ENSG00000186501.10445.50070351.120900.343402.173401.48410HepG2AKAP8L
TMEM222ENSG00000186501.10395.56580243.920800.697404.859404.09470HepG2BOP1
TMEM222ENSG00000186501.10727.81490449.298200.695806.069904.95620HepG2CIRBP
TMEM222ENSG00000186501.10475.57730349.401600.444703.711002.96170HepG2CKAP4
TMEM222ENSG00000186501.10515.29090401.013600.361602.281701.68830HepG2CELF1
TMEM222ENSG00000186501.10539.34540431.259900.322602.122401.46030HepG2DAZAP1
TMEM222ENSG00000186501.10442.25890323.220600.452303.856702.89190HepG2DDX19B
TMEM222ENSG00000186501.10340.21660249.293800.448502.487801.39410HepG2DDX1
TMEM222ENSG00000186501.10472.74200334.361200.499502.253601.63200HepG2DKC1
TMEM222ENSG00000186501.10316.52640244.445200.372701.904901.31000HepG2DNAJC21
TMEM222ENSG00000186501.10909.98950499.554000.865108.510307.39120HepG2EIF4A3
TMEM222ENSG00000186501.10627.59680467.636800.424302.358301.74120HepG2G3BP1
TMEM222ENSG00000186501.10382.29750246.787200.631303.987003.23160HepG2HNRNPA1
TMEM222ENSG00000186501.10481.72450274.507500.811306.657705.62010HepG2HNRNPC
TMEM222ENSG00000186501.10357.33280473.75680-0.406902.115101.49890HepG2HNRNPK
TMEM222ENSG00000186501.10513.80890392.866500.387102.128001.52720HepG2HNRNPL
TMEM222ENSG00000186501.10531.79800405.547500.390902.350301.68110HepG2IGF2BP1
TMEM222ENSG00000186501.10630.78320475.307200.408202.344801.71760HepG2IGF2BP2
TMEM222ENSG00000186501.10352.51900278.545900.339702.155901.49980HepG2ILF2
TMEM222ENSG00000186501.10610.22470332.902200.874106.317605.05090HepG2LARP4
TMEM222ENSG00000186501.10700.34330504.395000.473402.224401.63400HepG2MAGOH
TMEM222ENSG00000186501.10541.70730427.632500.341002.008501.35580HepG2NOL12
TMEM222ENSG00000186501.10373.65470522.83110-0.484604.253503.60720HepG2PTBP1
TMEM222ENSG00000186501.10562.27030408.192800.461902.962302.34890HepG2PUF60
TMEM222ENSG00000186501.10650.54670433.291300.586207.285206.41750HepG2PUM1
TMEM222ENSG00000186501.10438.60340566.30870-0.368702.547701.94450HepG2QKI
TMEM222ENSG00000186501.10462.58090321.734400.523702.602001.64060HepG2RBM27
TMEM222ENSG00000186501.10431.59160261.263700.724103.925002.65900HepG2RCC2
TMEM222ENSG00000186501.10378.76960227.601300.734703.825603.11350HepG2RPS19
TMEM222ENSG00000186501.10412.39750296.702300.474902.158501.44640HepG2RPS2
TMEM222ENSG00000186501.10306.18830145.845101.069902.812501.44720HepG2SF1
TMEM222ENSG00000186501.10785.35220417.008000.913207.918406.73640HepG2SF3A3
TMEM222ENSG00000186501.10330.30290239.803400.461802.229801.59250HepG2SF3B1
TMEM222ENSG00000186501.10402.02660283.193900.505404.117203.35930HepG2SMN1
TMEM222ENSG00000186501.10720.40680558.256200.367803.351702.81670HepG2SRFBP1
TMEM222ENSG00000186501.10341.73140568.20480-0.733508.436007.71230HepG2SRSF1
TMEM222ENSG00000186501.10606.89190403.003000.590506.099205.22150HepG2SRSF5
TMEM222ENSG00000186501.10680.89400484.692800.490305.254904.59180HepG2SSB
TMEM222ENSG00000186501.10282.35590510.65820-0.854809.845608.89300HepG2TAF15
TMEM222ENSG00000186501.10359.46870469.29580-0.384602.439001.65180HepG2TIA1
TMEM222ENSG00000186501.10523.90750264.962700.9834011.9866011.07370HepG2TIAL1
TMEM222ENSG00000186501.10414.66610267.340900.633205.803505.04070HepG2TRIM56
TMEM222ENSG00000186501.10589.18050398.749000.563104.367003.23810HepG2TUFM
TMEM222ENSG00000186501.10305.66590151.594001.011602.517801.58040HepG2U2AF2
TMEM222ENSG00000186501.10306.56400196.372900.642503.117702.31410HepG2UCHL5
TMEM222ENSG00000186501.10587.03520357.049400.717206.410205.56140HepG2UTP3
TMEM222ENSG00000186501.10546.98310327.290800.740804.507803.59040HepG2XRN2
TMEM222ENSG00000186501.10466.10960309.899100.588805.650804.74340HepG2ZC3H8
TMEM222ENSG00000186501.10981.63730818.683300.261802.258901.73790K562AGGF1
TMEM222ENSG00000186501.102547.59750905.045901.4930023.2493021.73390K562AQR
TMEM222ENSG00000186501.10499.01140651.61090-0.384903.451402.37440K562BCLAF1
TMEM222ENSG00000186501.10554.30480426.812200.377002.489501.50380K562DDX3X
TMEM222ENSG00000186501.101116.96820813.452600.457404.721803.90250K562DDX47
TMEM222ENSG00000186501.10865.01140492.053400.813808.678606.97860K562EFTUD2
TMEM222ENSG00000186501.10997.57790814.010700.293302.513401.82230K562EIF2S2
TMEM222ENSG00000186501.10571.38450284.743001.0047013.0185011.25480K562EIF3G
TMEM222ENSG00000186501.10784.54590445.917900.815009.861808.30070K562EIF4A3
TMEM222ENSG00000186501.10512.53030401.577600.351902.391701.34070K562EIF4B
TMEM222ENSG00000186501.10586.06330389.243800.590305.292903.39810K562EWSR1
TMEM222ENSG00000186501.10792.18800604.605500.389702.727801.88510K562FIP1L1
TMEM222ENSG00000186501.10771.20710463.736600.7337010.212509.13410K562FXR1
TMEM222ENSG00000186501.1073.64720205.60340-1.481209.105107.67070K562G3BP2
TMEM222ENSG00000186501.101322.489601084.690900.285902.059801.40130K562GRSF1
TMEM222ENSG00000186501.101002.07140559.054700.8418011.5988010.44960K562HNRNPC
TMEM222ENSG00000186501.10536.47650366.876800.548103.126702.01260K562IGF2BP2
TMEM222ENSG00000186501.10572.12300385.293600.570304.841203.72110K562MAGOH
TMEM222ENSG00000186501.10760.62820550.655000.465902.905901.42930K562NUSAP1
TMEM222ENSG00000186501.10574.84090376.755300.609404.863603.02940K562PCBP1
TMEM222ENSG00000186501.10498.01640342.764900.538903.753002.61470K562PCBP2
TMEM222ENSG00000186501.10744.51580545.917200.447503.109601.58490K562PHF6
TMEM222ENSG00000186501.10966.65080478.827001.0134013.0959011.45410K562PRPF8
TMEM222ENSG00000186501.10778.45060501.289500.634906.007304.59670K562PSIP1
TMEM222ENSG00000186501.10571.93030374.357800.611305.720204.79440K562PTBP1
TMEM222ENSG00000186501.101412.967101028.745800.457704.695502.61330K562RBM17
TMEM222ENSG00000186501.10616.04020358.811800.779703.985002.95880K562RBM22
TMEM222ENSG00000186501.10851.07200487.671400.803307.300305.95790K562RPS19
TMEM222ENSG00000186501.10547.00140335.333100.705802.931501.89780K562RPS3
TMEM222ENSG00000186501.10814.55740437.039900.898203.399702.02880K562SF1
TMEM222ENSG00000186501.10976.10040755.396700.369702.975002.13140K562SF3A3
TMEM222ENSG00000186501.10397.14110213.771900.893508.785307.21400K562SF3B4
TMEM222ENSG00000186501.10995.33580532.737000.901704.259702.50400K562SFPQ
TMEM222ENSG00000186501.10833.83280501.981100.732002.833201.58930K562SNRNP200
TMEM222ENSG00000186501.10602.45430433.723000.474003.186402.06700K562SRFBP1
TMEM222ENSG00000186501.10508.07760367.026800.469103.136702.38760K562SRSF1
TMEM222ENSG00000186501.10450.12790323.683200.475702.745601.70080K562SRSF4
TMEM222ENSG00000186501.10512.39800346.706800.563403.388102.20630K562SRSF5
TMEM222ENSG00000186501.10107.54860201.82240-0.908102.777401.31030K562TAF15
TMEM222ENSG00000186501.10773.58930371.387501.0585011.7396010.11780K562TARDBP
TMEM222ENSG00000186501.10621.91660358.262900.795608.819207.24280K562TIA1
TMEM222ENSG00000186501.10607.19490351.722500.787606.455904.61910K562TRA2A
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for TMEM222 is not available on ENCORE database.





15 RBPs can affect the splicing of TMEM222 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SETMEM222ENSG00000186501.10chr1+276574752765762827657210276572952765856027658592-0.258000.000210.00592excludedK562SRSF1
SETMEM222ENSG00000186501.10chr1+276574752765762827657210276572952765856027658592-0.231000.000600.08408excludedK562MATR3
SETMEM222ENSG00000186501.10chr1+276574752765762827657210276572952765856027658592-0.274000.000030.01128excludedK562PCBP1
SETMEM222ENSG00000186501.10chr1+2765747527657628276572102765729527658560276585920.699000.000000.00000includedHepG2HNRNPK
SETMEM222ENSG00000186501.10chr1+2766115727661245276606412766077227661869276621390.083000.001010.05138includedK562EFTUD2
SETMEM222ENSG00000186501.10chr1+2765747527657628276572102765729527658560276585920.264000.000100.01417includedHepG2DDX6
SETMEM222ENSG00000186501.10chr1+276611572766124527660641276607722766186927662139-0.058000.000340.03797excludedHepG2SUPV3L1
SETMEM222ENSG00000186501.10chr1+276574752765762827657210276572952765856027658592-0.135000.000420.02447excludedHepG2PCBP1
SETMEM222ENSG00000186501.10chr1+276611572766124527660641276607722766186927662139-0.056000.000770.09190excludedK562ZC3H8
SETMEM222ENSG00000186501.10chr1+276574752765762827657210276572952765856027658592-0.179000.000110.02254excludedK562ZC3H8
SETMEM222ENSG00000186501.10chr1+2766115727661245276606412766077227661869276621390.195000.000170.01159includedK562HNRNPK
SETMEM222ENSG00000186501.10chr1+2765747527657628276572102765729527658560276585920.444000.000160.01093includedK562HNRNPK
A3SSTMEM222ENSG00000186501.10chr1+2765744127657628276574752765762827657169276572950.159000.006470.03625longerK562AQR
A3SSTMEM222ENSG00000186501.10chr1+2765713827657295276572102765729527648737276488820.108000.000000.00000longerK562AQR
A3SSTMEM222ENSG00000186501.10chr1+2766042927660545276604482766054527658401276585920.167000.003760.02249longerK562AQR
RITMEM222ENSG00000186501.10chr1+276606412766289027660641276607722766186927662890-0.129000.000010.00280excludedK562MATR3
RITMEM222ENSG00000186501.10chr1+2766064127662890276606412766077227661869276628900.073000.006930.06526includedHepG2QKI
RITMEM222ENSG00000186501.10chr1+276606412766289027660641276607722766186927662890-0.059000.000620.00854excludedK562RBM15
RITMEM222ENSG00000186501.10chr1+2766064127662890276606412766077227661869276628900.057000.006400.07878includedHepG2G3BP1
RITMEM222ENSG00000186501.10chr1+276606412766289027660641276607722766186927662890-0.085000.000000.00014excludedK562XRCC6
RITMEM222ENSG00000186501.10chr1+2766064127662890276606412766077227661869276628900.051000.007850.06350includedHepG2RBM22
RITMEM222ENSG00000186501.10chr1+2766064127662890276606412766077227661869276628900.133000.000010.00022includedHepG2HNRNPK
RITMEM222ENSG00000186501.10chr1+2766064127662890276606412766077227661869276628900.142000.000010.00016includedK562EFTUD2
RITMEM222ENSG00000186501.10chr1+2766064127662890276606412766077227661869276628900.210000.000000.00000includedK562AQR
RITMEM222ENSG00000186501.10chr1+276606412766289027660641276607722766186927662890-0.110000.000700.01660excludedK562PTBP1
MXETMEM222ENSG00000186501.10chr1+2765721027657295276574752765762827648744276488822765856027658592-0.102000.003580.027202includedK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for TMEM222 is not avaliable on ENCORE database.