SRP19

General Information

Gene Name       : SRP19
Gene ID             : ENSG00000153037.14
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: SRP19)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878SRP19ENSG00000153037.14126.11106.58116.34ENCSR000AEF
HepG2SRP19ENSG00000153037.1487.71133.32110.51ENCSR985KAT
K562SRP19ENSG00000153037.1499.20107.26103.23ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for SRP19 is not avaliable on ENCORE database.



Proteins bound to RNA
  • SRP19 RNA is bound by 9 proteins.  







eCLIP assay for SRP19 is not avaliable on ENCORE database.





9 proteins are bound to SRP19 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr5112203294112203403+3'-UTR,intron-Distal5.519479.50640K562RBM15
chr5112203493112203559+3'-UTR,intron-Distal4.9212536.05793K562PABPC4
chr5112203053112203117+3'-UTR,CDS,intron-Distal,intron-Proximal4.566614.79708HepG2U2AF2
chr5112197017112197111+5'-UTR,CDS,intron-Distal5.161734.38825K562DROSHA
chr5112197054112197119+5'-UTR,CDS,intron-Distal,intron-Proximal5.048896.89039K562RBM15
chr5112197016112197064+5'-UTR,intron-Distal5.100246.15796HepG2DDX3X
chr5112197011112197073+5'-UTR,intron-Distal4.6520321.03966K562DDX3X
chr5112198246112198380+3'-UTR,CDS,intron-Distal,intron-Proximal4.796206.08664K562BUD13
chr5112197101112197174+CDS,intron-Distal,intron-Proximal5.093255.68502HepG2PRPF8
chr5112198232112198380+3'-UTR,CDS,intron-Distal,intron-Proximal3.746186.32052K562AQR
chr5112197073112197115+CDS,intron-Distal,intron-Proximal4.8739919.42045K562DDX3X
chr5112198215112198278+3'-UTR,CDS,intron-Distal3.005873.06971K562YBX3
chr5112198204112198269+3'-UTR,CDS,intron-Distal,intron-Proximal3.285207.35825K562DDX3X
chr5112198280112198337+intron-Distal,intron-Proximal3.879544.75655HepG2PRPF8
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for SRP19 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for SRP19 is not available on ENCORE database.

  • 79 RBPs can affect the levels of SRP19.  








The Knockdown/knockout RNA-Seq assay for SRP19 is not available on ENCORE database.





79 RBPs can affect the gene expression of SRP19 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
SRP19ENSG00000153037.81039.00990737.998800.493403.268902.69730HepG2AKAP1
SRP19ENSG00000153037.8595.53330931.56940-0.6455010.122408.94610HepG2AUH
SRP19ENSG00000153037.8374.80520529.03700-0.497202.706101.81550HepG2BCLAF1
SRP19ENSG00000153037.8590.729201205.44190-1.029004.043602.85250HepG2CCAR1
SRP19ENSG00000153037.8743.18880580.161300.357202.089501.41120HepG2CIRBP
SRP19ENSG00000153037.8725.537001202.10980-0.728408.575207.42210HepG2CPSF6
SRP19ENSG00000153037.81118.32660707.011400.661404.398203.62370HepG2DDX3X
SRP19ENSG00000153037.81012.22310735.950500.459702.366501.43060HepG2DDX5
SRP19ENSG00000153037.8566.69200417.293400.441402.694401.59670HepG2EFTUD2
SRP19ENSG00000153037.8557.69810406.334500.456702.858701.94290HepG2EIF3D
SRP19ENSG00000153037.8979.57690805.879200.281502.419901.62850HepG2EIF4G1
SRP19ENSG00000153037.8602.10120407.212000.564104.512503.10120HepG2FASTKD2
SRP19ENSG00000153037.8807.10170521.027300.631303.177901.68520HepG2HLTF
SRP19ENSG00000153037.8668.759801072.02450-0.680802.649001.94630HepG2HNRNPF
SRP19ENSG00000153037.8959.476801300.42650-0.438703.451402.75730HepG2HNRNPLL
SRP19ENSG00000153037.8626.973201055.66480-0.751702.813402.08310HepG2IGF2BP1
SRP19ENSG00000153037.8636.11240489.089700.379103.573902.75020HepG2ILF2
SRP19ENSG00000153037.8370.70830516.01800-0.477104.545903.24950HepG2KIF1C
SRP19ENSG00000153037.81004.04320674.257500.574303.846902.36440HepG2KRR1
SRP19ENSG00000153037.8579.04460411.806500.491603.331702.08690HepG2LARP7
SRP19ENSG00000153037.8618.10310413.106300.581204.037301.99650HepG2LSM11
SRP19ENSG00000153037.8939.31350651.085600.528703.395702.66840HepG2MAGOH
SRP19ENSG00000153037.8916.20090654.765500.484603.197302.52370HepG2MATR3
SRP19ENSG00000153037.8991.60540662.321400.582106.830305.61550HepG2MSI2
SRP19ENSG00000153037.8866.10000670.218000.369802.186201.62110HepG2NCBP2
SRP19ENSG00000153037.8731.05390473.924400.625202.089501.34540HepG2PARN
SRP19ENSG00000153037.8709.34120584.593700.278902.194101.69610HepG2PTBP1
SRP19ENSG00000153037.8581.48680773.22700-0.411102.815502.21440HepG2PUF60
SRP19ENSG00000153037.8881.19940497.399400.825004.944304.01640HepG2RAVER1
SRP19ENSG00000153037.81138.23370893.962300.348403.236702.68820HepG2RBM22
SRP19ENSG00000153037.8507.07750650.58370-0.359502.629002.09930HepG2NELFE
SRP19ENSG00000153037.8597.64260395.366300.596005.022404.22220HepG2RPS19
SRP19ENSG00000153037.8687.27750457.967800.585504.413203.41490HepG2RPS2
SRP19ENSG00000153037.8623.83080426.395700.548902.865802.21240HepG2SAFB2
SRP19ENSG00000153037.8599.39480396.835500.594904.353303.18550HepG2SERBP1
SRP19ENSG00000153037.8611.99300853.94060-0.480602.254001.64430HepG2SF3A3
SRP19ENSG00000153037.81048.385001287.15940-0.296002.090001.47070HepG2SF3B1
SRP19ENSG00000153037.8443.26750608.60960-0.457303.842303.16350HepG2SF3B4
SRP19ENSG00000153037.8600.03090741.38060-0.305202.724202.02720HepG2SLBP
SRP19ENSG00000153037.8713.53180497.234200.521006.509905.58940HepG2SMN1
SRP19ENSG00000153037.81262.187901009.695900.321904.031603.46040HepG2SRFBP1
SRP19ENSG00000153037.8966.48870635.268000.605308.925108.18380HepG2SRSF1
SRP19ENSG00000153037.8770.789901385.00500-0.845508.581006.73550HepG2SRSF3
SRP19ENSG00000153037.8711.634501053.13660-0.565501.917601.32700HepG2SRSF7
SRP19ENSG00000153037.8366.46640516.83420-0.496003.328402.73450HepG2SRSF9
SRP19ENSG00000153037.81048.11560876.652300.257602.413601.92770HepG2SSB
SRP19ENSG00000153037.8683.30550465.199300.554605.326004.67850HepG2TIAL1
SRP19ENSG00000153037.81378.04790699.883700.977307.433706.41060HepG2U2AF1
SRP19ENSG00000153037.8183.13900352.02660-0.942707.179705.94950HepG2UCHL5
SRP19ENSG00000153037.8993.66070731.157100.442505.257704.47680HepG2UTP3
SRP19ENSG00000153037.8898.97120546.864500.717005.057703.65250HepG2XRCC6
SRP19ENSG00000153037.81181.39830832.900900.504209.156108.30860HepG2ZNF622
SRP19ENSG00000153037.8848.48610624.789400.441403.534802.18430K562AARS
SRP19ENSG00000153037.81583.214901223.669000.371503.112201.79300K562APOBEC3C
SRP19ENSG00000153037.8964.852701246.68510-0.369702.761802.17420K562AQR
SRP19ENSG00000153037.8482.39150608.21430-0.334402.493301.58470K562BCLAF1
SRP19ENSG00000153037.81547.557502145.29210-0.471202.392301.41660K562CNOT7
SRP19ENSG00000153037.8855.734701191.63060-0.477703.948803.01290K562CPSF6
SRP19ENSG00000153037.8323.98250461.42120-0.510203.231302.07900K562CSTF2
SRP19ENSG00000153037.82221.315801705.255200.381304.478403.22840K562CELF1
SRP19ENSG00000153037.82440.005101334.756300.870205.884804.98530K562DDX47
SRP19ENSG00000153037.81495.709801191.903300.327503.908602.84370K562DKC1
SRP19ENSG00000153037.8886.43570592.032500.582206.873005.63100K562EIF3G
SRP19ENSG00000153037.8905.82190648.167800.482802.869902.14730K562G3BP2
SRP19ENSG00000153037.8480.46420683.79770-0.509104.007003.30490K562HNRNPC
SRP19ENSG00000153037.8460.01730610.56500-0.408502.672601.55380K562HNRNPF
SRP19ENSG00000153037.81475.23300817.801600.851002.269301.43060K562HNRNPM
SRP19ENSG00000153037.81900.004501348.387500.494702.293601.56430K562HSPD1
SRP19ENSG00000153037.81427.362701175.515700.280002.653701.84760K562KIF1C
SRP19ENSG00000153037.8727.33300971.42580-0.417502.222701.39670K562KRR1
SRP19ENSG00000153037.8878.733301110.54830-0.337802.575501.73500K562METAP2
SRP19ENSG00000153037.81347.40210923.040900.545603.926102.82430K562NAA15
SRP19ENSG00000153037.82086.044301516.953300.459504.725702.74520K562NOL12
SRP19ENSG00000153037.8849.113901061.50170-0.322103.872703.00680K562NSUN2
SRP19ENSG00000153037.8559.70570756.72640-0.435102.763901.93350K562PCBP3
SRP19ENSG00000153037.81848.926901424.979200.375603.806102.13120K562PNPT1
SRP19ENSG00000153037.8700.88860485.901900.528403.892203.00450K562PRPF8
SRP19ENSG00000153037.8927.36070723.342000.358402.971202.28510K562PTBP1
SRP19ENSG00000153037.81722.631901098.463000.649007.694406.83600K562PUS1
SRP19ENSG00000153037.81279.211601070.352000.257102.282601.73490K562RBM15
SRP19ENSG00000153037.8958.71180494.993200.953608.103806.68890K562RPS19
SRP19ENSG00000153037.8667.620701047.50360-0.649909.612208.16140K562SF3A3
SRP19ENSG00000153037.8317.35530530.17640-0.740406.105704.41700K562SRFBP1
SRP19ENSG00000153037.8492.99940686.03190-0.476703.604202.38040K562SRSF4
SRP19ENSG00000153037.8765.98760582.191100.395703.195302.31230K562SYNCRIP
SRP19ENSG00000153037.8434.38880589.68900-0.441002.197701.37290K562TIAL1
SRP19ENSG00000153037.8433.97240626.36770-0.529404.147702.94190K562TRIM56
SRP19ENSG00000153037.8894.46480628.320500.509403.317202.09690K562U2AF1
SRP19ENSG00000153037.8962.92750648.906800.569306.754105.50710K562U2AF2
SRP19ENSG00000153037.8321.95800497.96920-0.629204.219602.93530K562UCHL5
SRP19ENSG00000153037.81176.132501001.534500.231702.353501.56820K562WDR43
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for SRP19 is not available on ENCORE database.





6 RBPs can affect the splicing of SRP19 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SESRP19ENSG00000153037.8chr5+112200317112200429112200153112200225112203100112203421-0.139000.000000.00016excludedK562PRPF8
SESRP19ENSG00000153037.8chr5+112200317112200429112200153112200225112203100112203421-0.091000.000030.00490excludedHepG2PRPF8
SESRP19ENSG00000153037.8chr5+112200317112200429112200130112200225112203100112203421-0.066000.000000.00005excludedK562AQR
SESRP19ENSG00000153037.8chr5+112200317112200429112200153112200225112203100112203421-0.127000.000000.00000excludedHepG2SF3A3
A5SSSRP19ENSG00000153037.8chr5+1122003171122005091122003171122004291122031001122034210.085000.000000.00004longerK562AQR
A5SSSRP19ENSG00000153037.8chr5+1122003171122005091122003171122004291122031001122034210.082000.000000.00000longerHepG2SF3A3
MXESRP19ENSG00000153037.8chr5+112200153112200225112200317112200429112198204112198280112203068112203632-0.157000.002000.083432includedK562UTP18
MXESRP19ENSG00000153037.8chr5+112200153112200225112200317112200429112198058112198280112203100112203421-0.114000.000290.005912includedK562U2AF2
MXESRP19ENSG00000153037.8chr5+112200153112200225112200317112200429112198204112198280112203068112203632-0.339000.000220.050472includedHepG2CDC40
MXESRP19ENSG00000153037.8chr5+1122001531122002251122003171122004291121982041121982801122030681122036320.196000.000470.013271includedK562PRPF8

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for SRP19 is not avaliable on ENCORE database.