SPATS2

General Information

Gene Name : SPATS2
Gene ID : ENSG00000123352.17
Essential Gene : No

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: SPATS2)

Not Available

Antibody Validation

Bethyl Labs: A304-970A

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	SPATS2	ENSG00000123352.17	25.12	24.47	24.80	ENCSR000AEF
HepG2	SPATS2	ENSG00000123352.17	19.42	26.84	23.13	ENCSR985KAT
K562	SPATS2	ENSG00000123352.17	16.36	16.99	16.67	ENCSR000AEO

Assays

2 Released experiments are available on ENCORE database.

Assay Type	Exp_Name	ENCODE ID	Target label	Biosample	Status	Linked Antibody	Controls	Method	Note
knockdown followed by RNA-seq	SPATS2-BGKcLV33-K562		SPATS2	K562	Released			CRISPR	KD% = no band on the position,
knockdown followed by RNA-seq	SPATS2-BGKcLV33-K562	ENCSR535TPQ	SPATS2	K562	Released		ENCSR271ZAB	CRISPR	KD% = 53.3,50.8

eCLIP

No eCLIP experiment available

Antibody Validation

GeneName	Antibody_DCC_ID	Product_ID	Lot_ID	Phosphate	HepG2 Primary Validation	K562 Primary Validation	HepG2 Secondary Validation	K562 Secondary Validation
SPATS2	ENCAB243SMV	A304-970A	1					BGKcLV33-69, Released, ENCODE4

KD RNA-Seq

GeneName	Cell_Line	Method	Exp_ID	Control_ID	Sample_reps	Control_reps	KD%	Status	Project
SPATS2	K562	CRISPR			BGKcLV33-65,BGKcLV33-66	BGKcLV33-1,BGKcLV33-2	no band on the position,	Released	ENCODE4
SPATS2	K562	CRISPR	ENCSR535TPQ	ENCSR271ZAB	SPATS2-BGKcLV33-69,SPATS2-BGKcLV33-70	NT-BGKcLV33-1,NT-BGKcLV33-2	53.3,50.8	Released	ENCODE4
SPATS2	HepG2	CRISPR			BGHcLV31-65,BGHcLV31-66	BGHcLV31-1,BGHcLV31-2	0.0,0.0	NotSatisfied	ENCODE4
SPATS2	HepG2	CRISPR			BGHcLV34-57,BGHcLV34-58	BGHcLV34-1,BGHcLV34-2	NO CLEAR BAND ON THE POSITION,	NotSatisfied	ENCORE2

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela
SPATS2	Product_ID: A304-970A Lot_ID: 1 Source: Bethyl Labs Target Name: SPATS2-human

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for SPATS2 is not avaliable on ENCORE database.

Proteins bound to RNA

SPATS2 RNA is bound by 23 proteins.

eCLIP assay for SPATS2 is not avaliable on ENCORE database.

23 proteins are bound to SPATS2 RNA:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr12	49908313	49908387	+	3'-UTR,CDS,intron-Proximal	4.29902	5.52578	K562	U2AF2
chr12	49883271	49883358	+	3'-UTR,CDS,intron-Proximal	4.18948	6.81381	K562	DDX24
chr12	49912875	49912959	+	3'-UTR,CDS,intron-Distal	3.53178	3.32039	HepG2	PPIG
chr12	49908332	49908384	+	3'-UTR,CDS,intron-Proximal	4.33362	3.87582	K562	ZNF622
chr12	49888672	49888783	+	3'-UTR,CDS	3.23935	5.04943	K562	ZNF622
chr12	49883335	49883357	+	3'-UTR,CDS,intron-Proximal	4.07061	6.22576	HepG2	BCLAF1
chr12	49888566	49888668	+	3'-UTR,CDS	3.81421	5.56491	HepG2	BCLAF1
chr12	49908334	49908402	+	3'-UTR,CDS,intron-Proximal	4.20518	5.52342	HepG2	PPIG
chr12	49883277	49883335	+	3'-UTR,CDS	4.56241	8.85766	HepG2	BCLAF1
chr12	49908308	49908380	+	3'-UTR,CDS,intron-Proximal	3.94786	6.17334	HepG2	U2AF2
chr12	49883282	49883357	+	3'-UTR,CDS,intron-Proximal	3.45357	6.54511	K562	UCHL5
chr12	49908335	49908398	+	3'-UTR,CDS,intron-Proximal	3.07309	6.09950	HepG2	BCLAF1
chr12	49883246	49883277	+	3'-UTR,CDS,intron-Proximal	4.93056	5.68196	HepG2	BCLAF1
chr12	49883305	49883357	+	3'-UTR,CDS,intron-Proximal	5.09459	6.64300	K562	ZNF622
chr12	49884463	49884515	+	3'-UTR,CDS,intron-Proximal	4.28382	6.65960	HepG2	BCLAF1
chr12	49884463	49884515	+	3'-UTR,CDS,intron-Proximal	3.09840	4.44630	K562	ZNF622
chr12	49761190	49761299	+	5'-UTR,intron-Distal,intron-Proximal	3.29018	4.85044	HepG2	GTF2F1
chr12	49761205	49761288	+	5'-UTR,intron-Distal,intron-Proximal	3.44968	3.87702	HepG2	NCBP2
chr12	49761184	49761264	+	5'-UTR,intron-Distal,intron-Proximal	3.20156	4.79299	HepG2	PRPF4
chr12	49761290	49761349	+	5'-UTR,intron-Distal,intron-Proximal	3.44217	3.90826	K562	ZNF622
chr12	49878378	49878450	+	CDS	3.81005	11.95754	HepG2	BCLAF1
chr12	49878375	49878452	+	CDS	3.37833	5.17903	K562	UCHL5
chr12	49890678	49890721	+	CDS	4.30535	3.45943	HepG2	BCLAF1
chr12	49893927	49893992	+	CDS,intron-Proximal	3.27832	3.12941	K562	UCHL5
chr12	49878370	49878453	+	CDS,intron-Proximal	3.70117	9.56042	K562	ZNF622
chr12	49762505	49762632	+	intron-Distal	4.31662	4.31512	K562	KHSRP
chr12	49761521	49761589	+	intron-Distal	3.14987	4.27427	HepG2	CSTF2T
chr12	49905604	49905732	+	intron-Distal	3.37045	3.42396	HepG2	U2AF2
chr12	49790567	49790617	+	intron-Distal	4.19005	4.03915	HepG2	SUGP2
chr12	49761464	49761598	+	intron-Distal,intron-Proximal	5.02335	7.68230	K562	CSTF2T
chr12	49769407	49769478	+	intron-Distal	3.45736	3.89652	HepG2	SFPQ
chr12	49769400	49769512	+	intron-Distal	4.08749	3.49011	K562	KHSRP
chr12	49761481	49761565	+	intron-Distal	4.12661	3.11728	K562	FAM120A
chr12	49906595	49906644	+	intron-Distal,intron-Proximal	4.02156	3.50006	HepG2	SF3B4
chr12	49790779	49790829	+	intron-Distal	4.09727	3.29248	HepG2	SUGP2
chr12	49761467	49761520	+	intron-Distal,intron-Proximal	4.11218	3.90256	HepG2	PRPF4
chr12	49777834	49777929	+	intron-Distal	3.99780	4.52298	HepG2	QKI
chr12	49766512	49766618	+	intron-Distal	4.44152	4.27402	K562	CSTF2T
chr12	49843671	49843842	+	intron-Distal	4.04634	4.54401	K562	KHSRP
chr12	49903330	49903398	+	intron-Distal	4.99606	6.75669	HepG2	ILF3
chr12	49901516	49901685	+	intron-Distal	3.11053	3.19528	HepG2	KHSRP
chr12	49906993	49907064	+	intron-Distal	4.74667	5.71021	K562	TARDBP
chr12	49778302	49778407	+	intron-Distal	4.74771	6.75032	K562	TARDBP
chr12	49761531	49761583	+	intron-Distal	3.67385	6.87013	HepG2	FAM120A
chr12	49901707	49901825	+	intron-Distal	4.25488	4.10688	K562	KHSRP
chr12	49768933	49769063	+	intron-Distal	3.75297	6.76965	K562	EIF4G2
chr12	49791561	49791616	+	intron-Distal	5.49901	6.34931	HepG2	XPO5
chr12	49800689	49800786	+	intron-Distal	3.49628	3.35377	HepG2	QKI
chr12	49776338	49776408	+	intron-Distal	3.99084	3.84727	K562	QKI
chr12	49776338	49776449	+	intron-Distal	4.52405	21.16194	HepG2	QKI
chr12	49766517	49766605	+	intron-Distal	3.88422	4.06464	HepG2	CSTF2
chr12	49766380	49766448	+	intron-Distal	3.37868	3.48890	K562	KHSRP
chr12	49835277	49835376	+	intron-Distal	4.31708	3.91475	K562	PTBP1
chr12	49761466	49761531	+	intron-Distal,intron-Proximal	4.48806	13.83304	HepG2	FAM120A
chr12	49901565	49901673	+	intron-Distal	3.89318	7.22994	K562	KHSRP
chr12	49772392	49772493	+	intron-Distal	3.24549	3.56061	HepG2	STAU2
chr12	49858852	49858963	+	intron-Distal	3.85503	3.42844	K562	KHSRP
chr12	49761473	49761535	+	intron-Distal	5.32290	4.95161	K562	GTF2F1
chr12	49790207	49790272	+	intron-Distal	4.91066	7.65425	HepG2	SUGP2
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

eCLIP assay for SPATS2 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for SPATS2 is not available on ENCORE database.
66 RBPs can affect the levels of SPATS2.

The Knockdown/knockout RNA-Seq assay for SPATS2 is not available on ENCORE database.

66 RBPs can affect the gene expression of SPATS2 :

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
SPATS2	ENSG00000123352.13	817.47410	639.58840	0.35390	2.09080	1.40340	HepG2	ASCC1
SPATS2	ENSG00000123352.13	414.70570	566.58890	-0.45020	2.14000	1.31940	HepG2	BCCIP
SPATS2	ENSG00000123352.13	344.13640	492.33370	-0.51670	2.62870	1.75000	HepG2	BCLAF1
SPATS2	ENSG00000123352.13	746.54400	587.94490	0.34440	2.15370	1.62060	HepG2	BOP1
SPATS2	ENSG00000123352.13	1025.09710	607.64370	0.75440	6.54190	5.38870	HepG2	CIRBP
SPATS2	ENSG00000123352.13	580.89220	740.49920	-0.35020	1.82090	1.30210	HepG2	DDX3X
SPATS2	ENSG00000123352.13	882.14700	635.95810	0.47200	2.97690	2.33830	HepG2	DDX6
SPATS2	ENSG00000123352.13	447.10040	619.77570	-0.47110	4.27760	3.42000	HepG2	DNAJC21
SPATS2	ENSG00000123352.13	488.02230	614.29000	-0.33200	2.94410	2.27430	HepG2	DNAJC2
SPATS2	ENSG00000123352.13	631.91140	474.91790	0.41190	2.44560	1.59080	HepG2	EIF3D
SPATS2	ENSG00000123352.13	1096.34770	657.90790	0.73660	5.60250	4.64650	HepG2	EIF4B
SPATS2	ENSG00000123352.13	651.61720	387.11570	0.75120	7.54930	6.28950	HepG2	FUBP3
SPATS2	ENSG00000123352.13	886.50630	671.32100	0.40100	2.65530	1.78440	HepG2	G3BP2
SPATS2	ENSG00000123352.13	464.13370	611.87550	-0.39870	2.03990	1.48490	HepG2	GPKOW
SPATS2	ENSG00000123352.13	810.29970	640.19060	0.33990	2.06680	1.45730	HepG2	HNRNPK
SPATS2	ENSG00000123352.13	493.51560	691.38490	-0.48640	5.38870	4.56440	HepG2	HNRNPU
SPATS2	ENSG00000123352.13	764.13950	1139.25590	-0.57620	4.10720	3.09150	HepG2	LARP4
SPATS2	ENSG00000123352.13	400.02810	640.05470	-0.67810	5.73790	4.00690	HepG2	LIN28B
SPATS2	ENSG00000123352.13	562.04380	711.09820	-0.33940	2.14850	1.43070	HepG2	MSI2
SPATS2	ENSG00000123352.13	495.86370	701.96980	-0.50150	3.15210	2.47840	HepG2	NCBP2
SPATS2	ENSG00000123352.13	884.40570	1065.77380	-0.26910	2.13000	1.45890	HepG2	NOL12
SPATS2	ENSG00000123352.13	427.32330	684.35800	-0.67940	8.81910	7.44750	HepG2	PARN
SPATS2	ENSG00000123352.13	927.36270	643.98580	0.52600	7.13470	6.23450	HepG2	PCBP1
SPATS2	ENSG00000123352.13	751.15440	614.92050	0.28860	2.32890	1.61250	HepG2	PRPF4
SPATS2	ENSG00000123352.13	708.79550	1017.37040	-0.52140	5.20840	4.42280	HepG2	PUF60
SPATS2	ENSG00000123352.13	835.17500	1079.97910	-0.37090	5.03300	4.28130	HepG2	PUM1
SPATS2	ENSG00000123352.13	824.13990	1079.19310	-0.38900	3.66010	2.89400	HepG2	PUM2
SPATS2	ENSG00000123352.13	811.38900	644.08120	0.33310	2.16590	1.56400	HepG2	RBM25
SPATS2	ENSG00000123352.13	558.94870	734.93980	-0.39490	2.24380	1.35960	HepG2	RBM27
SPATS2	ENSG00000123352.13	934.03660	679.24130	0.45950	5.43960	4.61190	HepG2	RECQL
SPATS2	ENSG00000123352.13	614.21110	890.44370	-0.53580	4.69590	3.83710	HepG2	RPLP0
SPATS2	ENSG00000123352.13	343.67630	462.15830	-0.42730	2.59020	1.99430	HepG2	RPS19
SPATS2	ENSG00000123352.13	515.42620	677.82920	-0.39520	2.24280	1.51810	HepG2	RPS2
SPATS2	ENSG00000123352.13	642.52400	425.13340	0.59570	3.99960	3.07600	HepG2	RRP9
SPATS2	ENSG00000123352.13	451.37650	577.97260	-0.35670	1.91720	1.32310	HepG2	SF3B1
SPATS2	ENSG00000123352.13	793.29730	975.49030	-0.29830	3.10310	2.36650	HepG2	SLBP
SPATS2	ENSG00000123352.13	430.25110	643.09450	-0.57990	2.87660	2.07940	HepG2	SNRNP70
SPATS2	ENSG00000123352.13	1363.63520	1048.96390	0.37840	5.09180	4.47040	HepG2	SRFBP1
SPATS2	ENSG00000123352.13	1051.76540	712.10010	0.56260	8.22080	7.50480	HepG2	SRSF1
SPATS2	ENSG00000123352.13	630.74850	1004.49960	-0.67130	11.15760	10.01390	HepG2	SRSF5
SPATS2	ENSG00000123352.13	569.54080	812.13950	-0.51190	6.01090	5.04800	HepG2	SRSF7
SPATS2	ENSG00000123352.13	953.23600	1142.39750	-0.26120	2.64260	2.03130	HepG2	SUCLG1
SPATS2	ENSG00000123352.13	405.48720	554.56310	-0.45170	2.16590	1.55740	HepG2	SUPV3L1
SPATS2	ENSG00000123352.13	669.70160	993.92040	-0.56960	6.16620	4.78840	HepG2	TUFM
SPATS2	ENSG00000123352.13	440.05600	751.58710	-0.77230	7.31630	6.30160	HepG2	U2AF1
SPATS2	ENSG00000123352.13	722.02600	1052.04420	-0.54310	4.13850	3.10460	HepG2	UBE2L3
SPATS2	ENSG00000123352.13	220.18630	327.60450	-0.57320	2.99450	2.20750	HepG2	UCHL5
SPATS2	ENSG00000123352.13	657.85490	838.65650	-0.35030	3.88010	3.26170	HepG2	ZNF622
SPATS2	ENSG00000123352.13	782.76990	927.36550	-0.24450	1.89350	1.40690	K562	AGGF1
SPATS2	ENSG00000123352.13	1295.79930	1019.02570	0.34660	2.78590	1.79920	K562	AKAP8
SPATS2	ENSG00000123352.13	1416.68560	1108.25960	0.35410	3.47920	2.13700	K562	CCDC124
SPATS2	ENSG00000123352.13	1071.88890	710.97110	0.59220	3.14520	2.00270	K562	CNOT7
SPATS2	ENSG00000123352.13	1198.74950	893.05100	0.42460	5.53980	4.66460	K562	DDX47
SPATS2	ENSG00000123352.13	765.37150	478.77110	0.67670	5.05780	3.60790	K562	EIF3D
SPATS2	ENSG00000123352.13	832.06340	612.18200	0.44260	3.63980	2.70180	K562	EIF4A3
SPATS2	ENSG00000123352.13	599.87610	443.40050	0.43600	2.56480	1.48690	K562	FKBP4
SPATS2	ENSG00000123352.13	946.49210	577.23300	0.71330	2.60280	1.43100	K562	HNRNPA2B1
SPATS2	ENSG00000123352.13	624.23200	474.50930	0.39550	2.11960	1.31150	K562	HNRNPM
SPATS2	ENSG00000123352.13	858.81100	692.52340	0.31040	2.56000	1.69930	K562	HNRNPU
SPATS2	ENSG00000123352.13	1245.60970	1024.07520	0.28240	2.23140	1.50010	K562	KIF1C
SPATS2	ENSG00000123352.13	1207.14040	980.28580	0.30020	2.28550	1.33790	K562	MAK16
SPATS2	ENSG00000123352.13	1651.07820	1147.22180	0.52520	6.41680	4.92240	K562	MBNL1
SPATS2	ENSG00000123352.13	1611.26960	1252.43430	0.36340	2.83060	2.00490	K562	PUF60
SPATS2	ENSG00000123352.13	603.33260	802.04340	-0.41070	2.83920	1.73150	K562	NELFE
SPATS2	ENSG00000123352.13	605.86670	443.25050	0.45080	2.49860	1.72370	K562	RPS19
SPATS2	ENSG00000123352.13	488.38770	650.73150	-0.41400	3.35790	2.41430	K562	SF3B4
SPATS2	ENSG00000123352.13	940.28690	743.63620	0.33840	3.60360	2.55110	K562	SRPK2
SPATS2	ENSG00000123352.13	1003.52850	779.28990	0.36470	3.04530	2.30580	K562	SRSF1
SPATS2	ENSG00000123352.13	684.31780	421.28020	0.69980	5.49890	4.02900	K562	SUPV3L1
SPATS2	ENSG00000123352.13	1072.37960	779.99140	0.45920	3.77980	2.95270	K562	UPF1
SPATS2	ENSG00000123352.13	1517.36470	1175.69970	0.36790	3.38520	1.94930	K562	WRN
SPATS2	ENSG00000123352.13	1138.98660	623.68380	0.86880	3.95360	1.89540	K562	YTHDC2
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for SPATS2 is not available on ENCORE database.

12 RBPs can affect the splicing of SPATS2 :

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	2ndExonStart	2ndExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP
SE	SPATS2	ENSG00000123352.13	chr12	+	49877518	49877634			49854552	49854820	49878372	49878452	0.05800	0.00012	0.00333	included	HepG2	U2AF1
SE	SPATS2	ENSG00000123352.13	chr12	+	49765010	49765073			49761302	49761370	49854552	49854820	0.49300	0.00045	0.04207	included	HepG2	QKI
SE	SPATS2	ENSG00000123352.13	chr12	+	49906644	49906688			49893852	49893988	49908337	49908396	0.33600	0.00083	0.01210	included	HepG2	U2AF2
SE	SPATS2	ENSG00000123352.13	chr12	+	49765010	49765073			49761302	49761370	49854552	49855012	-0.37000	0.00001	0.00016	excluded	K562	AQR
SE	SPATS2	ENSG00000123352.13	chr12	+	49912855	49912965			49908337	49908396	49916533	49916636	-0.12500	0.00007	0.00120	excluded	K562	AQR
SE	SPATS2	ENSG00000123352.13	chr12	+	49765010	49765073			49761302	49761370	49854552	49854820	-0.26300	0.00514	0.06350	excluded	K562	PUS1
SE	SPATS2	ENSG00000123352.13	chr12	+	49765010	49765073			49761302	49761370	49854552	49854820	-0.43100	0.00012	0.01238	excluded	HepG2	NCBP2
SE	SPATS2	ENSG00000123352.13	chr12	+	49765010	49765073			49761302	49761370	49854552	49854820	0.54700	0.00000	0.00057	included	HepG2	PTBP1
SE	SPATS2	ENSG00000123352.13	chr12	+	49765010	49765073			49761302	49761370	49854552	49854820	0.27900	0.00035	0.06755	included	K562	APOBEC3C
SE	SPATS2	ENSG00000123352.13	chr12	+	49765010	49765073			49761302	49761370	49854552	49854820	-0.32800	0.00101	0.07613	excluded	HepG2	DDX6
SE	SPATS2	ENSG00000123352.13	chr12	+	49848007	49848168			49761278	49761370	49854552	49854820	0.38700	0.00011	0.01218	included	K562	HNRNPL
SE	SPATS2	ENSG00000123352.13	chr12	+	49765010	49765073			49761302	49761370	49854552	49854820	0.32000	0.00098	0.02497	included	HepG2	SRSF1
SE	SPATS2	ENSG00000123352.13	chr12	+	49765010	49765073			49761302	49761370	49854552	49854820	0.34800	0.00184	0.07381	included	HepG2	SF3B4
A3SS	SPATS2	ENSG00000123352.13	chr12	+	49890593	49890672			49890615	49890672	49888523	49888785	0.10500	0.00099	0.00687	longer	K562	AQR
MXE	SPATS2	ENSG00000123352.13	chr12	+	49890593	49890792	49893852	49893988	49888523	49888785	49908337	49908396	0.08600	0.00035	0.00363	1included	K562	AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

SPATS2

General Information

Functions

Localization

Domains (AlphaFold: SPATS2)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for SPATS2 is not avaliable on ENCORE database.

23 proteins are bound to SPATS2 RNA:

eCLIP assay for SPATS2 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for SPATS2 is not available on ENCORE database.

66 RBPs can affect the gene expression of SPATS2 :

The Knockdown/knockout RNA-Seq assay for SPATS2 is not available on ENCORE database.

12 RBPs can affect the splicing of SPATS2 :

The Knockdown/knockout RNA-Seq assay for SPATS2 is not avaliable on ENCORE database.